Optimizing Palliative Medicine Support for Liver Transplant Candidates
1. Participants will be able to identify how a quality approach can be successfully used to improve access to palliative medicine for liver transplant candidates.2. Participants will be able to define methods which can be employed to improve collaboration between teams and alleviate quality gaps among unique patient populations. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Richard Guthrie, Rolland Dickson, David M H Chascsa, Matthew Martin, Beth Perry, Sue Weinhold, Kathleen Minner Source Type: research

Deep learning-based optimization of field geometry for total marrow irradiation delivered with volumetric modulated arc therapy
CONCLUSIONS: The generated field geometries were clinically acceptable and adequate, even for an MP with high level of expertise in TMI/TMLI. Incorporating the knowledge of the MPs into the development cycle was crucial for optimizing the models, especially in this scenario with limited data.PMID:38634859 | DOI:10.1002/mp.17089 (Source: Health Physics)
Source: Health Physics - April 18, 2024 Category: Physics Authors: Nicola Lambri Giorgio Longari Daniele Loiacono Ricardo Coimbra Brioso Leonardo Crespi Carmela Galdieri Francesca Lobefalo Giacomo Reggiori Roberto Rusconi Stefano Tomatis Luisa Bellu Stefania Bramanti Elena Clerici Chiara De Philippis Damiano Dei Pierina Source Type: research

Deep learning-based optimization of field geometry for total marrow irradiation delivered with volumetric modulated arc therapy
CONCLUSIONS: The generated field geometries were clinically acceptable and adequate, even for an MP with high level of expertise in TMI/TMLI. Incorporating the knowledge of the MPs into the development cycle was crucial for optimizing the models, especially in this scenario with limited data.PMID:38634859 | DOI:10.1002/mp.17089 (Source: Health Physics)
Source: Health Physics - April 18, 2024 Category: Physics Authors: Nicola Lambri Giorgio Longari Daniele Loiacono Ricardo Coimbra Brioso Leonardo Crespi Carmela Galdieri Francesca Lobefalo Giacomo Reggiori Roberto Rusconi Stefano Tomatis Luisa Bellu Stefania Bramanti Elena Clerici Chiara De Philippis Damiano Dei Pierina Source Type: research

Impact of donor characteristics on hepatocellular carcinoma recurrence after liver transplantation
Br J Surg. 2024 Apr 3;111(4):znae080. doi: 10.1093/bjs/znae080.NO ABSTRACTPMID:38630794 | DOI:10.1093/bjs/znae080 (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - April 17, 2024 Category: Surgery Authors: Miho Akabane Yuki Bekki Yuki Imaoka Yosuke Inaba Carlos O Esquivel Marc L Melcher Allison Kwong Kazunari Sasaki Source Type: research

Liver transplantation for hepatitis B virus-related cirrhosis with acute-on-chronic liver failure and grade 3-4 hepatic encephalopathy: Survival and quality of life
Chin Med J (Engl). 2024 Apr 17. doi: 10.1097/CM9.0000000000003037. Online ahead of print.NO ABSTRACTPMID:38630917 | DOI:10.1097/CM9.0000000000003037 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 17, 2024 Category: General Medicine Authors: Shaohua Shi Minghui Zhang Xuliang Chen Zhuoyi Wang Songming Ding Zhitao Chen Yu Yang Shusen Zheng Source Type: research

Impact of donor characteristics on hepatocellular carcinoma recurrence after liver transplantation
Br J Surg. 2024 Apr 3;111(4):znae080. doi: 10.1093/bjs/znae080.NO ABSTRACTPMID:38630794 | DOI:10.1093/bjs/znae080 (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - April 17, 2024 Category: Surgery Authors: Miho Akabane Yuki Bekki Yuki Imaoka Yosuke Inaba Carlos O Esquivel Marc L Melcher Allison Kwong Kazunari Sasaki Source Type: research

Prediction of type II diabetes mellitus based on demographic features by the use of machine learning classification algorithms — a study across Assam, India
ConclusionsThe study underscores lifestyle modifications for T2DM prevention, highlighting AI ’s potential in diagnosis and the impact of unhealthy habits on T2DM susceptibility. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 17, 2024 Category: Endocrinology Source Type: research

Analysis of donor morbidity in 177 donor hepatectomies for living donor liver transplant: Experience from a high-volume centre in western India
ConclusionDonor safety (outcome) is determined by meticulous donor surgery and good-quality remnant.Graphical abstract (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 17, 2024 Category: Gastroenterology Source Type: research

Treatment of Cavernous Transformation of Portal Vein Caused by Hepatic Cystic Echinococcosis Using Ex Vivo Liver Resection and Autotransplantation
CONCLUSIONS Through this paper, we aim to detail the treatment process, showcasing the feasibility and advantages of ELRA. Additionally, we propose a novel approach for the treatment of this disease, while emphasizing the importance of radical resection surgery to prevent long-term complications.PMID:38622855 | DOI:10.12659/AOT.942358 (Source: Annals of Transplantation)
Source: Annals of Transplantation - April 16, 2024 Category: Transplant Surgery Authors: Ayidu Reyimu Jiang Tiemin Shao Yingmei Zhu Xuepeng Guo Wenjiang Du Yuhao Dilixiati Halimulati Wusiman Ababokeli Aji Tuerganaili Wen Hao Source Type: research

Treatment of Cavernous Transformation of Portal Vein Caused by Hepatic Cystic Echinococcosis Using Ex Vivo Liver Resection and Autotransplantation
CONCLUSIONS Through this paper, we aim to detail the treatment process, showcasing the feasibility and advantages of ELRA. Additionally, we propose a novel approach for the treatment of this disease, while emphasizing the importance of radical resection surgery to prevent long-term complications.PMID:38622855 | DOI:10.12659/AOT.942358 (Source: Annals of Transplantation)
Source: Annals of Transplantation - April 16, 2024 Category: Transplant Surgery Authors: Ayidu Reyimu Jiang Tiemin Shao Yingmei Zhu Xuepeng Guo Wenjiang Du Yuhao Dilixiati Halimulati Wusiman Ababokeli Aji Tuerganaili Wen Hao Source Type: research

Treatment of Cavernous Transformation of Portal Vein Caused by Hepatic Cystic Echinococcosis Using Ex Vivo Liver Resection and Autotransplantation
CONCLUSIONS Through this paper, we aim to detail the treatment process, showcasing the feasibility and advantages of ELRA. Additionally, we propose a novel approach for the treatment of this disease, while emphasizing the importance of radical resection surgery to prevent long-term complications.PMID:38622855 | PMC:PMC11032082 | DOI:10.12659/AOT.942358 (Source: Annals of Transplantation)
Source: Annals of Transplantation - April 16, 2024 Category: Transplant Surgery Authors: Ayidu Reyimu Jiang Tiemin Shao Yingmei Zhu Xuepeng Guo Wenjiang Du Yuhao Dilixiati Halimulati Wusiman Ababokeli Aji Tuerganaili Wen Hao Source Type: research

Loss of SREBP-1c ameliorates iron-induced liver fibrosis by decreasing lipocalin-2
Experimental & Molecular Medicine, Published online: 16 April 2024; doi:10.1038/s12276-024-01213-2Sterol regulatory element-binding protein (SREBP)-1c plays a role in liver fat regulation and is elevated in nonalcoholic steatohepatitis (NASH). Researchers investigated role of SREBP-1c in NASH using mice models and patient samples, focusing on lipocalin-2 (LCN2) regulation. In NASH mice, LCN2 expression was increased, driven by SREBP-1c. LCN2 treatment increased iron accumulation and fibrosis-related gene expression in hepatic stellate cells, dependent on SREBP-1c. LCN2 expression correlated with inflammation and fibros...
Source: Experimental and Molecular Medicine - April 16, 2024 Category: Molecular Biology Authors: Eun-Ho Lee Jae-Ho Lee Do-Young Kim Young-Seung Lee Yunju Jo Tam Dao Kyung Eun Kim Dae-Kyu Song Ji Hae Seo Young-Kyo Seo Je Kyung Seong Changjong Moon Eugene Han Mi Kyung Kim Seungwan Ryu Minsang Shin Gu Seob Roh Hye Ra Jung Timothy F. Osborne Dongryeol Ry Source Type: research

Artificial intelligence in liver cancer — new tools for research and patient management
Nature Reviews Gastroenterology & Hepatology, Published online: 16 April 2024; doi:10.1038/s41575-024-00919-yArtificial intelligence (AI) is advancing rapidly and is already starting to transform cancer research and care. Here, the authors outline how AI could be incorporated into liver cancer management, highlighting areas with academic, commercial and clinical potential, as well as ongoing progress and pitfalls. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - April 16, 2024 Category: Gastroenterology Authors: Julien Calderaro Laura Žigutytė Daniel Truhn Ariel Jaffe Jakob Nikolas Kather Source Type: research