Psychosocial Issues Related to Donor's Decision-Making in Living Donor Liver Transplantation.
Abstract BACKGROUND The aim of this study was to investigate the detailed motives, concerns, and psychological defensiveness of living liver donor candidates in a Korean population. MATERIAL AND METHODS We analyzed data of 102 donor candidates obtained from routine psychosocial evaluation for living donor liver transplantation (LDLT) using descriptive methods. Donor candidates completed 2 questionnaires regarding their motivations and concerns, as well as a validity scale, the K scale from the Minnesota Multiphasic Personality Inventory-2. RESULTS Donor candidates were more likely to cite family-related issues (77...
Source: Annals of Transplantation - October 18, 2019 Category: Transplant Surgery Authors: Ryu S, Yoon SC, Hong KE, Kim JM Tags: Ann Transplant Source Type: research

Effects of a Structured Physical Activity Program on Serum Adipokines and Markers of Inflammation and Volume Overload in Kidney Transplant Recipients.
Abstract BACKGROUND Kidney transplantation (KTx) reverses most abnormalities related to chronic kidney disease (CKD), but sedentary lifestyle persists in most kidney graft recipients. Physical inactivity has been associated with altered adipokine profile and inflammation in CKD. We postulated that increased physical activity achieved through an individually-tailored program can reverse these changes. MATERIAL AND METHODS We included 25 clinically stable KTx recipients at least 12 months after transplantation and with eGFR>30 mL/min and 15 age-matched non-dialysis patients with CKD stage 3. Body composition, pat...
Source: Annals of Transplantation - October 8, 2019 Category: Transplant Surgery Authors: Muras-Szwedziak K, Masajtis-Zagajewska A, Pawłowicz E, Nowicki M Tags: Ann Transplant Source Type: research

Single Nucleotide Polymorphisms of Ubiquitin-Related Genes were Associated with Allograft Fibrosis of Renal Transplant Fibrosis.
CONCLUSIONS We are the first to reveal that mutations of rs644731 in the PIAS2 gene were significantly correlated with the progression of IF/TA in kidney transplant recipients. PMID: 31582715 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - October 4, 2019 Category: Transplant Surgery Authors: Gui Z, Li W, Fei S, Guo M, Chen H, Sun L, Han Z, Tao J, Ju X, Yang H, Wei JF, Tan R, Gu M Tags: Ann Transplant Source Type: research

Pulmonary Infection Within 100 Days After Transplantation Impaired Platelet Recovery in Patients with Hematologic Malignancies: A Propensity-Score-Matched Analysis.
Abstract BACKGROUND Pulmonary infection is one of the life-threatening complications occurring during allogeneic hematopoietic stem cell transplantation (alloHSCT), even when prophylactic measures have been employed. Few studies have investigated whether pulmonary infection affects platelet recovery during alloHSCT. MATERIAL AND METHODS We retrospectively reviewed 253 consecutive patients with hematologic diseases who received alloHSCT in our institute. Among them, 62 patients (25%) had pulmonary infection within 100 days after alloHSCT. Using the one-to-two propensity-score matching logistic model, 50 patients wi...
Source: Annals of Transplantation - September 27, 2019 Category: Transplant Surgery Authors: Wang R, Huang A, Chen Q, Wang L, Gao L, Qiu H, Ni X, Zhang W, Yang J, Wang J, Hu X Tags: Ann Transplant Source Type: research

Allogenic Tendon-Autologous Cartilage Cells Transplantation Enhances Adhesive/Growth Ability and Promotes Chondrogenesis in a Rabbit Model of Glenoid Labrum Damage.
CONCLUSIONS This study establishes the allogenic tendon-autologous cartilage cells reconstruction and transplantation approach and illustrated higher adhesive ability and growth ability, and better chondrogenesis in a rabbit model of glenoid labrum damage. PMID: 31527567 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - September 17, 2019 Category: Transplant Surgery Authors: Chen G, Chen P, You T, Jiang X, Li W, Jiang C Tags: Ann Transplant Source Type: research

Hepatitis B Vaccination in Patients with Liver Cirrhosis Evaluated for Liver Transplantation - A Simple Intervention Ensures High Adherence.
CONCLUSIONS Initiation of HBV vaccination during hospitalization and detailed recommendations on subsequent vaccinations in the discharge letter improve previously inadequate vaccination rates in the outpatient setting. Similar measures should be implemented at earlier time points of chronic liver diseases to achieve higher immune response rates. PMID: 31515466 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - September 13, 2019 Category: Transplant Surgery Authors: Herta T, Petroff D, Engelmann C, Herber A, Aehling N, Scheuermann U, Bartels M, Seehofer D, Berg T, Wiegand J Tags: Ann Transplant Source Type: research

A Prospective, Observational Study of Conversion From Immediate- to Prolonged-Release Tacrolimus in Renal Transplant Recipients in France: The OPALE Study.
CONCLUSIONS Favorable clinical outcomes and safety profiles were observed with conversion from immediate- to prolonged-release tacrolimus over 1 year following renal transplantation, with no marked differences between the early and late conversion groups. PMID: 31477681 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - September 3, 2019 Category: Transplant Surgery Authors: Moal V, Grimbert P, Beauvais A, Dubel L, Le Meur Y Tags: Ann Transplant Source Type: research

A Multicenter, Prospective, Observational Study of Conversion from Twice-Daily Immediate-Release to Once-Daily Prolonged-Release Tacrolimus in Liver Transplant Recipients in France: The COBALT Study.
CONCLUSIONS Conversion of liver transplant recipients from immediate-release to prolonged-release tacrolimus within three to 12 months of transplantation was easy to manage and associated with favorable clinical outcomes and safety profiles. PMID: 31451681 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - August 27, 2019 Category: Transplant Surgery Authors: Dumortier J, Duvoux C, Dubel L, Bazin F, Houssel-Debry P Tags: Ann Transplant Source Type: research

Recurrence of Hepatocellular Carcinoma After Liver Transplantation: A Single-Center Experience.
CONCLUSIONS Adherence to strictly defined selection criteria for LT in HCC patients guarantees the success of LT in HCC treatment. PMID: 31439828 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - August 23, 2019 Category: Transplant Surgery Authors: Zeair S, Rajchert J, Stasiuk R, Cyprys S, Miętkiewski J, Zasada-Cedro K, Karpińska E, Duczkowska M, Parczewski M, Wawrzynowicz-Syczewska M Tags: Ann Transplant Source Type: research

Prediction of Early Recurrence of Hepatocellular Carcinoma in Patients with Cirrhosis Who Had Received Deceased Donor Liver Transplantation: A Multicenter Study.
Abstract BACKGROUND Early recurrence after liver transplantation (LT) is still a clinical problem. This multicenter study evaluated the Milan, Hangzhou, and AFP model-based criteria for prediction of early recurrence of HCC in patients with cirrhosis who had undergone LT. MATERIAL AND METHODS From the China Liver Transplant Registry (CLTR) database, we analyzed data of 589 HCC patients who had undergone LT between Jan 2015 and Jan 2019. Imaging data and AFP levels were evaluated immediately before LT. Recurrence and overall survival rates at 2 years were tested using the Kaplan-Meier estimate. The Milan criteria, ...
Source: Annals of Transplantation - August 20, 2019 Category: Transplant Surgery Authors: Al-Ameri AAM, Wei X, Liu P, Lin L, Shao Z, Xie H, Zhou L, Zheng S, Xu X Tags: Ann Transplant Source Type: research

Analysis of Data from the Oxygen Persufflation in Liver Transplantation (OPAL) Study to Determine the Role of Factors Affecting the Hepatic Microcirculation and Early Allograft Dysfunction.
CONCLUSIONS Non-invasive investigations of the liver microcirculation and hemoglobin oxygenation were shown to be predictive factors for EAD following liver transplantation. PMID: 31417074 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - August 16, 2019 Category: Transplant Surgery Authors: Benkö T, Belker J, Gallinat A, Treckmann JW, Paul A, Minor T, Hoyer DP Tags: Ann Transplant Source Type: research

Alloresponses of Mixed Lymphocyte Hepatocyte Culture to Immunosuppressive Drugs as an In-Vitro Model of Hepatocyte Transplantation.
CONCLUSIONS Cyclosporine, Everolimus, and Belatacept suppressed the alloresponse of primary human hepatocytes in an MLHC without significant cytotoxicity or functional cell impairment. PMID: 31406101 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - August 13, 2019 Category: Transplant Surgery Authors: Oldhafer F, Wittauer EM, Falk CS, DeTemple DE, Beetz O, Timrott K, Kleine M, Vondran FWR Tags: Ann Transplant Source Type: research

Aplastic Anemia Preconditioned with Fludarabine, Cyclophosphamide, and Anti-Thymocyte Globulin.
CONCLUSIONS The FCA regimen for PBSCT in adult SAA patients compared favorably to the CA regimen. It can improve EFS and reduce graft rejection, especially for unrelated donor PBSCT. PMID: 31395850 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - August 9, 2019 Category: Transplant Surgery Authors: Yang D, Yang J, Hu X, Chen J, Gao L, Cheng H, Tang G, Luo Y, Zhang W, Wang J Tags: Ann Transplant Source Type: research

Development of Human Leukocyte Antigen (HLA) Antibodies Against Vascular Homograft Donor in Pediatric Heart Transplant Recipients.
CONCLUSIONS Our results suggest that the prevalence of DSAs against homograft donor prior to HTx is relatively rare. However, almost half of the patients developed DSAs against homograft post-HTx. The clinical importance of these antibodies warrants further studies. PMID: 31383839 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - August 6, 2019 Category: Transplant Surgery Authors: Jahnukainen T, Lauronen J, Raissadati A, Pihkala JI, Ylinen E, Puntila JT, Salminen JT, Pätilä T, Mattila IP, Jalanko HJ Tags: Ann Transplant Source Type: research

The Effect of Pediatric Living Donor Liver Transplantation on Neurocognitive Outcomes in Children.
CONCLUSIONS Liver transplantation clearly improves children's neurocognitive function. The postoperative neurocognition is closely related to pre-operation nutritional development. PMID: 31371696 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - August 2, 2019 Category: Transplant Surgery Authors: Sun Y, Jia L, Yu H, Zhu M, Sheng M, Yu W Tags: Ann Transplant Source Type: research

The Role of Pre-Procurement Pancreas Suitability Score (P-PASS) and Pancreas Donor Risk Index (PDRI) in the Outcome of Simultaneous Pancreas and Kidney or Pancreas After Kidney Transplantation.
, Mehrabi A Abstract BACKGROUND The pre-procurement pancreas suitability score (P-PASS) and the pancreas donor risk index (pDRI) are established predictive scores for graft survival and patient outcome following pancreatic transplantation. This retrospective study aimed to evaluate the predictive value of P-PASS and pDRI following simultaneous pancreas and kidney (SPK) transplantation, or pancreas after kidney (PAK) transplantation, and the clinical impact of donor-specific factors on the postoperative graft and recipient outcome at a single transplant center. MATERIAL AND METHODS The study included 105 patients w...
Source: Annals of Transplantation - July 26, 2019 Category: Transplant Surgery Authors: Franz C, Görtz M, Wührl M, Kulu Y, Hoffmann K, Hackert T, Morath C, Zeier M, Büchler MW, Mehrabi A Tags: Ann Transplant Source Type: research

Implantation Warm Ischemia Time in Kidney Transplant Recipients: Defining Its Limits and Impact on Early Graft Function.
Abstract BACKGROUND Prolonged cold ischemia is an established risk factor for poor early graft function (EGF). However, warm ischemia incurring during graft implantation has received little attention regarding its possible detrimental effect on EGF. The aim of our study was to examine the impact of recipient warm ischemia time on EGF. MATERIAL AND METHODS The data of 102 consecutive kidney transplants were analyzed to determine the association between duration of graft implantation time (IT) and EGF. Recipient IT groups were (GI) up to 45 min, (GII) 45-60 min, and (GIII)>60 min. EGF was categorized as immediate...
Source: Annals of Transplantation - July 23, 2019 Category: Transplant Surgery Authors: Khan TFT, Ahmad N, Serageldeen AS, Fourtounas K Tags: Ann Transplant Source Type: research

Effect of Pretransplant Dialysis Modality on Outcomes After Simultaneous Pancreas-Kidney Transplantation.
CONCLUSIONS Peritoneal dialysis is not a risk factor for postoperative complications after SPKT. PMID: 31320604 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - July 19, 2019 Category: Transplant Surgery Authors: Räihä J, Helanterä I, Ekstrand A, Nordin A, Sallinen V, Lempinen M Tags: Ann Transplant Source Type: research

Prognostic Impact of Peritransplant Serum Sodium Concentrations in Liver Transplantation.
CONCLUSIONS Rapid change in the sodium level might be caused by large amounts of blood transfusion products. This leads to a diminished short-term survival, as well as a higher rate of neurological complications. PMID: 31308357 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - July 16, 2019 Category: Transplant Surgery Authors: Mihaylov P, Nagai S, Ekser B, Mangus R, Fridell J, Kubal C Tags: Ann Transplant Source Type: research

Infectious Complications of Induction Therapies in Kidney Transplantation.
CONCLUSIONS This study demonstrated that a higher dosage of ATG in high-risk patients is associated with an increased risk of CMV disease and patient death, also, reducing the dosage may be a rational strategy for increasing graft and patient's survival. PMID: 31296835 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - July 12, 2019 Category: Transplant Surgery Authors: Bayraktar A, Catma Y, Akyildiz A, Demir E, Bakkaloglu H, Ucar AR, Dirim AB, Usta Akgul S, Temurhan S, Gok AFK, Ozluk Y, Kilicaslan I, Oguz FS, Sever MS, Aydin AE, Turkmen A Tags: Ann Transplant Source Type: research

Patient Knowledge, Attitudes, and Behaviors Associated with Organ Donation.
CONCLUSIONS Positive attitude towards organ transplantation and donation does not necessarily reflect positive behavior these 2 groups. PMID: 31285415 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - July 9, 2019 Category: Transplant Surgery Authors: Uyar M, Demir LS, Durduran Y, Evci R, Diker Ardıç Z, Şahin TK Tags: Ann Transplant Source Type: research

Effect of Portal Venous Pressure on Liver Function of Donors in Living Donor Liver Transplantation.
Abstract BACKGROUND We assessed the alterations in portal hemodynamics associated with donor right hepatectomy and its effects on functional regeneration of the remnant liver. MATERIAL AND METHODS This prospective study included 30 adult living donors who underwent right hepatectomy in the Liver Transplantation Unit, Faculty of Medicine, Cairo University from June 2015 to October 2016. During donor surgery, portal venous pressure (PVP) was measured using an antithrombotic catheter inserted into the main portal vein, and was measured before and after clamping of the right portal vein. Postoperatively, liver functio...
Source: Annals of Transplantation - July 5, 2019 Category: Transplant Surgery Authors: Khalil AH, Khattab M, Hosny KA, Elshazly M, Salah Eldin A, Hosny A Tags: Ann Transplant Source Type: research

Association of Clinical Factors with the Costs of Kidney Transplantation in the Current Era.
oniemi H Abstract BACKGROUND Kidney transplantation is reported to save costs compared to maintenance dialysis. We analyzed the current actual costs of kidney transplantation compared to dialysis, and analyzed risk factors for higher costs after transplantation. MATERIAL AND METHODS Altogether, 338 kidney transplant recipients between 2009 and 2014 were included in this study. All individual-level cost data from specialized health care and data from all reimbursed medication and travel costs were acquired from official records. Cost data were compared before and after transplantation within the same patients start...
Source: Annals of Transplantation - July 2, 2019 Category: Transplant Surgery Authors: Helanterä I, Isola T, Lehtonen TK, Åberg F, Lempinen M, Isoniemi H Tags: Ann Transplant Source Type: research

Effect of Calculated Panel Reactive Antibody Value on Waitlist Outcomes for Lung Transplant Candidates.
CONCLUSIONS CPRA values of greater than 50% are associated with significantly lower rates of transplantation and higher waitlist mortality. PMID: 31249284 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - June 28, 2019 Category: Transplant Surgery Authors: Aversa M, Benvenuto L, Kim H, Shah L, Robbins H, Stanifer BP, D'Ovidio F, Vasilescu ER, Sonett J, Arcasoy SM Tags: Ann Transplant Source Type: research

Risk Factors for Transplant Outcomes in Children and Adolescents with Non-Malignant Diseases Following Allogeneic Hematopoietic Stem Cell Transplantation.
The objective of this study was the analysis of transplant outcomes and survival in children treated with allogeneic hematopoietic cell transplantation (alloHCT) for non-malignant disorders, with a focus on risk factor analysis of transplant-related mortality (TRM). MATERIAL AND METHODS The treatment outcome was analyzed retrospectively in 10 consecutive years in 4 pediatric transplant centers in Poland. To compare the outcomes, patient data were analyzed according to the diagnosis, age at transplant, donor type, stem cell source, conditioning regimens, transplanted CD34+ cells dose, and pediatric TRM score. RESULTS From 1...
Source: Annals of Transplantation - June 25, 2019 Category: Transplant Surgery Authors: Zaucha-Prażmo A, Sadurska E, Pieczonka A, Goździk J, Dębski R, Drabko K, Zawitkowska J, Lejman M, Wachowiak J, Styczyński J, Kowalczyk JR Tags: Ann Transplant Source Type: research

Haploidentical, Unmanipulated Granulocyte Colony-Stimulating Factor (G-CSF)-Primed Peripheral Blood Stem Cell Transplants for Acute Myeloid Leukemia (AML) in Remission: A Single Center Experience.
CONCLUSIONS Our results showed that unmanipulated haploidentical transplantation with G-CSF primed PBSC alone as a graft source could be an acceptable alternative post-remission treatment for high-risk or intermediate-risk AML patients in CR1 lacking a matched donor. PMID: 31221952 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - June 21, 2019 Category: Transplant Surgery Authors: Luo L, Fang S, Zhao S, Li F, Zhou Y, Guan L, Yang N, Gu Z, Lin T, Wang F, Zhu C, Huang W, Liu D, Gao C Tags: Ann Transplant Source Type: research

Alcohol Use Relapse Following Liver Transplantation for Alcoholic Liver Disease.
Abstract BACKGROUND Alcohol use disorders affect 10% of the European population. Alcohol-related liver disease (ALD) is the most common indication for liver transplantation in Slovakia. The aim of this study was to determine the proportion of patients with ALD who received a liver transplant who had alcohol relapsed, and the risk factors for alcohol relapse, as well as to compare clinical outcomes according to relapse. MATERIAL AND METHODS A retrospective study of consecutive patients with ALD, who underwent liver transplantation in a single transplant center between May 2008 and December 2017. We included adult p...
Source: Annals of Transplantation - June 18, 2019 Category: Transplant Surgery Authors: Skladany L, Adamcova Selcanova S, Koller T Tags: Ann Transplant Source Type: research

ABO Blood Type Incompatibility Is Not a Risk Factor of Outcomes for Acute Myeloid Leukemia (AML) Patients After Unmanipulated Haplo-identical Peripheral Blood Hematopoietic Stem Cell Transplantation.
CONCLUSIONS This study demonstrated ABO incompatibility is not an independent risk factor of outcomes for AML patients who received unmanipulated haplo-identical peripheral blood HSCT. ABO compatibility might have limited value in haplo-identical donor selection. PMID: 31197126 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - June 14, 2019 Category: Transplant Surgery Authors: Yang N, Guan L, Liu Z, Ding Y, Zhu C, Luo L, Wang F, Fang S, Gao Z, Gu Z, Gao C Tags: Ann Transplant Source Type: research

Metabolomic Characterization of Human Model of Liver Rejection Identifies Aberrancies Linked to Cyclooxygenase (COX) and Nitric Oxide Synthase (NOS).
CONCLUSIONS Hepatic metabolic aberrancies associated with cyclooxygenase and nitric oxide synthase function occur contemporaneous with ALR. Additional studies are required to better characterize the role of these metabolic pathways to enhance utility of the metabolomics approach in diagnosis and outcomes of ALR. PMID: 31182705 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - June 11, 2019 Category: Transplant Surgery Authors: Skill NJ, Elliott CM, Ceballos B, Saxena R, Pepin R, Bettcher L, Ellensberg M, Raftery D, Malucio MA, Ekser B, Mangus RS, Kubal CA Tags: Ann Transplant Source Type: research

Outcome and Prognostic Factors of High-Risk Acute Myeloid Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation.
This study retrospectively analyzed 126 patients with HR-AML after allogeneic hematopoietic stem cell transplantation (allo-HCST). RESULTS The disease-free survival (DFS) rates of 1 year and 3 years were 58.83% (95%CI: 50.75-68.20%) and 53.09% (95%CI: 44.59-63.22%) respectively. The cumulative relapse rates of 1 year and 3 years were 21.1% (95%CI: 14.4-28.8%) and 25.9% (95%CI: 18.1-34.5%) respectively. The cumulative incidences of III to IV acute graft-versus-host disease (aGVHD) for 100 days was 8.70% (95%CI: 4.6-14.5%). The cumulative rate of extensive chronic graft-versus-host disease (cGVHD) for 1-year was 4.1% (95%CI:...
Source: Annals of Transplantation - June 7, 2019 Category: Transplant Surgery Authors: Zhu CY, Chen GF, Zhou W, Hou C, Wang XK, Wang FY, Yang N, Wang L, Fang S, Luo L, Guan LX, Zhang R, Liu YC, Dou LP, Gao CJ Tags: Ann Transplant Source Type: research

The Effect of Donor Age and Recipient Characteristics on Renal Outcomes in Patients Receiving Prolonged-Release Tacrolimus After Liver Transplantation: Post-Hoc Analyses of the DIAMOND Study.
CONCLUSIONS Pre-transplantation factors, such as renal function and donor age, could guide the choice of prolonged-release tacrolimus regimen following liver transplantation. PMID: 31160549 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - June 4, 2019 Category: Transplant Surgery Authors: Trunečka P, Klempnauer J, Bechstein WO, Pirenne J, Bennet W, Zhao A, Isoniemi H, Rostaing L, Settmacher U, Mönch C, Brown M, Undre N, Kazeem G, Tisone G Tags: Ann Transplant Source Type: research

Evolution of Indications for Liver Transplantation (LTx) in the Years 2001-2017 in Poland.
CONCLUSIONS The analyzed data suggest that HCV infections are a significant public health problem in Poland, as is also reflected by the growing number of LTx performed due to HCC. To limit the numbers of HCV and HCC cases, immediate implementation of a Polish National Program against HCV should be considered. PMID: 31147531 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - May 31, 2019 Category: Transplant Surgery Authors: Koczkodaj P, Straś W, Czerwiński J, Małkowski P, Panczyk M, Gotlib J Tags: Ann Transplant Source Type: research

Reduced Clostridioides difficile Tests Among Solid Organ Transplant Recipients Through a Diagnostic Stewardship Bundled Intervention.
CONCLUSIONS CCDS may be a helpful and safe adjunctive strategy to reduce unnecessary testing in accordance with guideline recommendations among solid organ transplant recipients. PMID: 31133632 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - May 28, 2019 Category: Transplant Surgery Authors: Madden GR, Sifri CD Tags: Ann Transplant Source Type: research

Comparison of Ipsilateral and Contralateral Simultaneous Pancreas and Kidney Transplantation: A Single-Center Analysis with 5-Year Outcome.
CONCLUSIONS There were no significant differences in overall outcomes. iSPK is a safe procedure, which proves similar patient and graft survival as with cSPK. Both procedures have comparable surgical complication rates. iSPK is a safe and quicker procedure that allows for preservation of the contralateral side for potential subsequent transplants. PMID: 31123244 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - May 24, 2019 Category: Transplant Surgery Authors: Papachristos S, Tavakoli A, Dhanda R, Pararajasingam R, Campbell T, Forgacs B Tags: Ann Transplant Source Type: research

Urinary and Serum Biomarkers for Prediction of Acute Kidney Injury in Patients Undergoing Liver Transplantation.
Abstract Acute kidney injury (AKI) is a frequent and serious complication of orthotopic liver transplantation (OLT), with a significant impact on mortality, graft survival, and chronic kidney disease. Currently, the diagnosis of AKI is based on changes in serum creatinine, which is a late marker, usually rising when there is already significant damage to the renal parenchyma. During the last 2 decades, various biomarkers have been studied in many clinical situations, mostly after cardiac surgery, in drug-induced AKI, or in sepsis. The present article summarizes the data on those biomarkers that have been evaluated...
Source: Annals of Transplantation - May 21, 2019 Category: Transplant Surgery Authors: Lewandowska L, Małyszko J, Joanna Matuszkiewicz-Rowińska J Tags: Ann Transplant Source Type: research

Prediction of Three-Year Mortality After Deceased Donor Kidney Transplantation in Adults with Pre-Transplant Donor and Recipient Variables.
CONCLUSIONS Older, highly immunized or high urgency transplant candidates with anticipated longer cold ischemic times, who were transplanted with the indication of diabetic nephropathy should receive donor organs with no HLA DR mismatches to improve their mortality risk. PMID: 31097680 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - May 17, 2019 Category: Transplant Surgery Authors: Schwager Y, Littbarski SA, Nolte A, Kaltenborn A, Emmanouilidis N, Kleine-Döpke D, Klempnauer J, Schrem H Tags: Ann Transplant Source Type: research

Pharmacokinetic Profile of Prolonged-Release Tacrolimus When Administered via Nasogastric Tube in De Novo Liver Transplantation: A Sub-Study of the DIAMOND Trial.
CONCLUSIONS In contrast to previously reported findings in healthy volunteers, nasogastric administration of prolonged--release tacrolimus suspension in liver transplant patients did not substantially affect the PK profile of tacrolimus vs. intact capsules. Nasogastric administration is thus a feasible option to ensure appropriate early tacrolimus exposure in de novo liver transplant recipients. PMID: 31086126 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - May 14, 2019 Category: Transplant Surgery Authors: Undre N, Baccarani U, Britz R, Popescu I Tags: Ann Transplant Source Type: research

Prediction of Nonadherence and Renal Prognosis by Pre-Transplantation Serum Phosphate Levels.
Abstract BACKGROUND Identifying characteristics of patients at high risk of poor adherence before transplantation would be advantageous. However, the optimal approach for characterizing such patients remains unknown. We aimed to evaluate the association between factors for hemodialysis nonadherence and post-transplant renal prognosis. We hypothesized that these factors would influence post-transplantation adherence and worsen renal prognosis. MATERIAL AND METHODS We reviewed patients on hemodialysis who underwent kidney transplantation at our hospital between 2000 and 2017 to identify risk factors associated with ...
Source: Annals of Transplantation - May 10, 2019 Category: Transplant Surgery Authors: Kitamura M, Mochizuki Y, Kitamura S, Mukae Y, Nakanishi H, Ota Y, Muta K, Yamashita H, Obata Y, Iwata T, Nishikido M, Kawanami S, Takashima M, Sasaki H, Sakai H, Mukae H, Nishino T Tags: Ann Transplant Source Type: research

Costs of Long-Term Post-Transplantation Care in Kidney Transplant Recipients.
CONCLUSIONS From the perspective of a transplant center, costs of long-term post-kidney transplantation care did not increase in the late period, even as long as 25 years after transplantation. Our results confirmed that kidney transplantation is a modality of renal replacement therapy that can be associated with economic benefits even when considering long-term post-transplantation care. PMID: 31061380 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - May 7, 2019 Category: Transplant Surgery Authors: Łabuś A, Niemczyk M, Czyżewski Ł, Fliszkiewicz M, Kulesza A, Mucha K, Pączek L Tags: Ann Transplant Source Type: research

Risk Factors for High Mortality on the Liver Transplant Waiting List in Times of Organ Shortage: A Single-Center Analysis.
Abstract BACKGROUND Germany has the highest rate of patients dying or becoming unfit for transplant while waitlisted within the Eurotransplant region. Therefore, the aim of the current study was to analyze mortality as well as risk factors for mortality of candidates listed for liver transplantation at our center. MATERIAL AND METHODS Between 01/2011 and 12/2013, 481 adult patients were listed for primary liver transplantation (LT) at a single German center. Clinical and laboratory parameters were prospectively collected and retrospectively analyzed by univariable and multivariable logistic regression and Cox prop...
Source: Annals of Transplantation - May 3, 2019 Category: Transplant Surgery Authors: Husen P, Hornung J, Benko T, Klein C, Willuweit K, Buechter M, Saner FH, Paul A, Treckmann JW, Hoyer DP Tags: Ann Transplant Source Type: research

Living Anonymous Renal Donors Do Not Regret: Intermediate and Long-Term Follow-Up with a Focus on Motives and Psychosocial Outcomes.
CONCLUSIONS Swedish LADs are very satisfied and medical outcomes are acceptable. We propose that the transplant community and the National Board of Health and Welfare take a more active approach to informing the general public about LAD. PMID: 31023996 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - April 26, 2019 Category: Transplant Surgery Authors: Wadström J, von Zur-Mühlen B, Lennerling A, Westman K, Wennberg L, Fehrman Ekholm I Tags: Ann Transplant Source Type: research

Role of Allelic Imbalance in Predicting Hepatocellular Carcinoma (HCC) Recurrence Risk After Liver Transplant.
CONCLUSIONS AI analysis could have prognostic value in risk management of HCC recurrence after LT, especially for early recurrence. PMID: 31015392 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - April 24, 2019 Category: Transplant Surgery Authors: Pagano D, Barbera F, Conaldi PG, Seidita A, Di Francesco F, Di Carlo D, Bàrbara M, Tuzzolino F, Luca A, Gruttadauria S Tags: Ann Transplant Source Type: research

Study of Hepatic Vascular Dynamics Based on Symmetrical Pulsating Perfusion.
CONCLUSIONS The SPF perfusion can clean the vascular wall more thoroughly with less injury. PMID: 31000689 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - April 19, 2019 Category: Transplant Surgery Authors: Liu J, Tian L, Wang S, Luo Z Tags: Ann Transplant Source Type: research

Clinical Efficacy of Pretransplant Vaccination for Preventing Herpes Zoster After Living Donor Liver Transplantation in Recipients Age 50 Years and Older.
Abstract BACKGROUND There have been no reports concerning the efficacy of pretransplant herpes zoster (HZ) vaccination following living donor liver transplantation (LDLT). MATERIAL AND METHODS From January 2013 to May 2016, 24 patients age 50 years and older received vaccination of HZ prior to transplantation and underwent LDLT at a single institution. We compared this to the 1-year HZ incidence of unvaccinated recipients (N=180) who underwent LDLT in the same time period. RESULTS For general characteristics, the MELD scores (p
Source: Annals of Transplantation - April 17, 2019 Category: Transplant Surgery Authors: Cho CW, Kim JM, Choi GS, Joh JW Tags: Ann Transplant Source Type: research

Endovascular Interventions in Vascular Complications After Simultaneous Pancreas and Kidney Transplantations: A Single-Center Experience.
CONCLUSIONS Intravenous interventions in patients with a transplanted or retransplanted pancreas are safe and feasible. It is a technically demanding procedure, but the risk of kidney graft function deterioration, as well as of bleeding due to the high dose of heparin used, is lower than with open vascular surgery. PMID: 30975974 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - April 12, 2019 Category: Transplant Surgery Authors: Surowiecka-Pastewka A, Matejak-Górska M, Frączek M, Sklinda K, Walecki J, Durlik M Tags: Ann Transplant Source Type: research

Donor-Dependent Factors Influencing Contamination Rates of Conjunctival Swabs of Human Donor Eyes.
CONCLUSIONS Donors with the diagnosis of a carcinoma or metastases seemed to be predisposed to increased conjunctival swab contamination risk. PMID: 30967524 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - April 10, 2019 Category: Transplant Surgery Authors: Röck T, Blumenstock G, Bartz-Schmidt KU, Bramkamp M, Landenberger J, Röck D Tags: Ann Transplant Source Type: research

Cystic Fibrosis: From Qualification to Lung Transplantation, a Single Center Experience.
CONCLUSIONS Lung transplantation improves respiratory capacity of CF patients and prolongs their life. PMID: 30948702 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - April 5, 2019 Category: Transplant Surgery Authors: Ochman M, Latos M, Urlik M, Stącel T, Nęcki M, Tatoj Z, Zawadzki F, Wajda-Pokrontka M, Przybyłowski P, Zembala M Tags: Ann Transplant Source Type: research

Outcome of Rituximab-Based Treatment for Post-Transplant Lymphoproliferative Disorder After Allogeneic Hematopoietic Stem Cell Transplantation: A Single-Center Experience.
Abstract BACKGROUND Post-transplant lymphoproliferative disorder (PTLD) is a rare complication following solid organ transplantation and allogeneic hematopoietic stem cell transplantation (Allo-HSCT), which gives rise to high mortality rates. MATERIAL AND METHODS This was a single-center retrospective analysis based on 27 patients who were diagnosed with PTLD following Allo-HSCT between January 1, 2007 and June 2018 at the Chinese PLA General Hospital. The purpose of this analysis was to investigate responses and prognostic factors of rituximab-based treatment. RESULTS Twenty-seven patients were treated with ritux...
Source: Annals of Transplantation - April 3, 2019 Category: Transplant Surgery Authors: Zhu CY, Zhao SS, Wang XK, Wang L, Wang FY, Fang S, Liu ZX, Guan LX, Liu YC, Ding Y, Dou LP, Wang LL, Gao CJ Tags: Ann Transplant Source Type: research

Re: Association Between Renal Dysfunction and Major Adverse Cardiac Events After Liver Transplantation: Evidence From an International Randomized Trial of Everolimus-Based Immunosuppression.
Abstract Ann Transplant. 2018 Oct 26;23:751-757. doi: 10.12659/AOT.911030. PMID: 30361470, PMCID: PMC6248043 In the paper, the sentence on page 754, first column, lines 4, 5, and 6 has been incorrectly written:  At the month 24 study visit, mean (SD) eGFR was 74.7 (26.1), 67.8 (21.0), and 77.5 (26.2) mL/min/1.73 m2 in the EVR/rTAC, TAC Elimination, and TAC Control groups, respectively (p=0.007). The corrected sentence should read:  At the 24-month study visit, mean (SD) eGFR was 74.7 (26.1), 67.8 (21.0), and 77.5 (26.2) mL/min/1.73 m2 in the EVR/rTAC, TAC Control, and TAC Elimination groups, respectively...
Source: Annals of Transplantation - March 29, 2019 Category: Transplant Surgery Authors: Saliba F, Fischer L, de Simone P, Bernhardt P, Bader G, Fung J Tags: Ann Transplant Source Type: research

Clinical Characteristics of Acute Appendicitis in Kidney Transplant Recipients.
Abstract BACKGROUND Clinical characteristics of acute appendicitis in kidney transplant recipients may be different from those in the general population due to kidney transplant recipient's immunosuppressive state and position change of appendix caused by graft. MATERIAL AND METHODS Clinical characteristics of 10 cases of acute appendicitis among 2880 cases of kidney transplantation were evaluated, including diagnostic rate, location of appendix and complication in kidney transplant recipients. RESULTS Acute appendicitis was suspected in 9 of 10 patients (90%) with acute appendicitis based on clinical and laborato...
Source: Annals of Transplantation - March 26, 2019 Category: Transplant Surgery Authors: Kwon SH, Park SH, Lee HY, Ko EJ, Ban TH, Chung BH, Yang CW Tags: Ann Transplant Source Type: research