Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation
Ann Transplant. 2023 Aug 15;28:e939750. doi: 10.12659/AOT.939750.ABSTRACTA number types of extracellular DNA (eg, cell-free, cfDNA) circulate in human blood, including mitochondrial, transcriptome, and regulatory DNA, usually at low concentrations. Larger amounts of cfDNA appear in any inflammatory condition, including organ damage due to a variety of reasons. The role of cfDNA in solid organ transplantation is discussed in this review as a valuable additional tool in the standard of care of transplant patients. Post-transplant monitoring requires the use of high-quality biomarkers for early detection of graft damage or re...
Source: Annals of Transplantation - August 15, 2023 Category: Transplant Surgery Authors: Joanna Raszeja-Wyszomirska Micha ł Macech Monika Kolanowska Marek Krawczyk S ławomir Nazarewski Anna W ójcicka Jolanta Ma łyszko Source Type: research

Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation
Ann Transplant. 2023 Aug 15;28:e939750. doi: 10.12659/AOT.939750.ABSTRACTA number types of extracellular DNA (eg, cell-free, cfDNA) circulate in human blood, including mitochondrial, transcriptome, and regulatory DNA, usually at low concentrations. Larger amounts of cfDNA appear in any inflammatory condition, including organ damage due to a variety of reasons. The role of cfDNA in solid organ transplantation is discussed in this review as a valuable additional tool in the standard of care of transplant patients. Post-transplant monitoring requires the use of high-quality biomarkers for early detection of graft damage or re...
Source: Annals of Transplantation - August 15, 2023 Category: Transplant Surgery Authors: Joanna Raszeja-Wyszomirska Micha ł Macech Monika Kolanowska Marek Krawczyk S ławomir Nazarewski Anna W ójcicka Jolanta Ma łyszko Source Type: research

Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation
Ann Transplant. 2023 Aug 15;28:e939750. doi: 10.12659/AOT.939750.ABSTRACTA number types of extracellular DNA (eg, cell-free, cfDNA) circulate in human blood, including mitochondrial, transcriptome, and regulatory DNA, usually at low concentrations. Larger amounts of cfDNA appear in any inflammatory condition, including organ damage due to a variety of reasons. The role of cfDNA in solid organ transplantation is discussed in this review as a valuable additional tool in the standard of care of transplant patients. Post-transplant monitoring requires the use of high-quality biomarkers for early detection of graft damage or re...
Source: Annals of Transplantation - August 15, 2023 Category: Transplant Surgery Authors: Joanna Raszeja-Wyszomirska Micha ł Macech Monika Kolanowska Marek Krawczyk S ławomir Nazarewski Anna W ójcicka Jolanta Ma łyszko Source Type: research

Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation
Ann Transplant. 2023 Aug 15;28:e939750. doi: 10.12659/AOT.939750.ABSTRACTA number types of extracellular DNA (eg, cell-free, cfDNA) circulate in human blood, including mitochondrial, transcriptome, and regulatory DNA, usually at low concentrations. Larger amounts of cfDNA appear in any inflammatory condition, including organ damage due to a variety of reasons. The role of cfDNA in solid organ transplantation is discussed in this review as a valuable additional tool in the standard of care of transplant patients. Post-transplant monitoring requires the use of high-quality biomarkers for early detection of graft damage or re...
Source: Annals of Transplantation - August 15, 2023 Category: Transplant Surgery Authors: Joanna Raszeja-Wyszomirska Micha ł Macech Monika Kolanowska Marek Krawczyk S ławomir Nazarewski Anna W ójcicka Jolanta Ma łyszko Source Type: research

Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation
Ann Transplant. 2023 Aug 15;28:e939750. doi: 10.12659/AOT.939750.ABSTRACTA number types of extracellular DNA (eg, cell-free, cfDNA) circulate in human blood, including mitochondrial, transcriptome, and regulatory DNA, usually at low concentrations. Larger amounts of cfDNA appear in any inflammatory condition, including organ damage due to a variety of reasons. The role of cfDNA in solid organ transplantation is discussed in this review as a valuable additional tool in the standard of care of transplant patients. Post-transplant monitoring requires the use of high-quality biomarkers for early detection of graft damage or re...
Source: Annals of Transplantation - August 15, 2023 Category: Transplant Surgery Authors: Joanna Raszeja-Wyszomirska Micha ł Macech Monika Kolanowska Marek Krawczyk S ławomir Nazarewski Anna W ójcicka Jolanta Ma łyszko Source Type: research

Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation
Ann Transplant. 2023 Aug 15;28:e939750. doi: 10.12659/AOT.939750.ABSTRACTA number types of extracellular DNA (eg, cell-free, cfDNA) circulate in human blood, including mitochondrial, transcriptome, and regulatory DNA, usually at low concentrations. Larger amounts of cfDNA appear in any inflammatory condition, including organ damage due to a variety of reasons. The role of cfDNA in solid organ transplantation is discussed in this review as a valuable additional tool in the standard of care of transplant patients. Post-transplant monitoring requires the use of high-quality biomarkers for early detection of graft damage or re...
Source: Annals of Transplantation - August 15, 2023 Category: Transplant Surgery Authors: Joanna Raszeja-Wyszomirska Micha ł Macech Monika Kolanowska Marek Krawczyk S ławomir Nazarewski Anna W ójcicka Jolanta Ma łyszko Source Type: research

Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation
Ann Transplant. 2023 Aug 15;28:e939750. doi: 10.12659/AOT.939750.ABSTRACTA number types of extracellular DNA (eg, cell-free, cfDNA) circulate in human blood, including mitochondrial, transcriptome, and regulatory DNA, usually at low concentrations. Larger amounts of cfDNA appear in any inflammatory condition, including organ damage due to a variety of reasons. The role of cfDNA in solid organ transplantation is discussed in this review as a valuable additional tool in the standard of care of transplant patients. Post-transplant monitoring requires the use of high-quality biomarkers for early detection of graft damage or re...
Source: Annals of Transplantation - August 15, 2023 Category: Transplant Surgery Authors: Joanna Raszeja-Wyszomirska Micha ł Macech Monika Kolanowska Marek Krawczyk S ławomir Nazarewski Anna W ójcicka Jolanta Ma łyszko Source Type: research

Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation
Ann Transplant. 2023 Aug 15;28:e939750. doi: 10.12659/AOT.939750.ABSTRACTA number types of extracellular DNA (eg, cell-free, cfDNA) circulate in human blood, including mitochondrial, transcriptome, and regulatory DNA, usually at low concentrations. Larger amounts of cfDNA appear in any inflammatory condition, including organ damage due to a variety of reasons. The role of cfDNA in solid organ transplantation is discussed in this review as a valuable additional tool in the standard of care of transplant patients. Post-transplant monitoring requires the use of high-quality biomarkers for early detection of graft damage or re...
Source: Annals of Transplantation - August 15, 2023 Category: Transplant Surgery Authors: Joanna Raszeja-Wyszomirska Micha ł Macech Monika Kolanowska Marek Krawczyk S ławomir Nazarewski Anna W ójcicka Jolanta Ma łyszko Source Type: research

Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation
Ann Transplant. 2023 Aug 15;28:e939750. doi: 10.12659/AOT.939750.ABSTRACTA number types of extracellular DNA (eg, cell-free, cfDNA) circulate in human blood, including mitochondrial, transcriptome, and regulatory DNA, usually at low concentrations. Larger amounts of cfDNA appear in any inflammatory condition, including organ damage due to a variety of reasons. The role of cfDNA in solid organ transplantation is discussed in this review as a valuable additional tool in the standard of care of transplant patients. Post-transplant monitoring requires the use of high-quality biomarkers for early detection of graft damage or re...
Source: Annals of Transplantation - August 15, 2023 Category: Transplant Surgery Authors: Joanna Raszeja-Wyszomirska Micha ł Macech Monika Kolanowska Marek Krawczyk S ławomir Nazarewski Anna W ójcicka Jolanta Ma łyszko Source Type: research

Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation
Ann Transplant. 2023 Aug 15;28:e939750. doi: 10.12659/AOT.939750.ABSTRACTA number types of extracellular DNA (eg, cell-free, cfDNA) circulate in human blood, including mitochondrial, transcriptome, and regulatory DNA, usually at low concentrations. Larger amounts of cfDNA appear in any inflammatory condition, including organ damage due to a variety of reasons. The role of cfDNA in solid organ transplantation is discussed in this review as a valuable additional tool in the standard of care of transplant patients. Post-transplant monitoring requires the use of high-quality biomarkers for early detection of graft damage or re...
Source: Annals of Transplantation - August 15, 2023 Category: Transplant Surgery Authors: Joanna Raszeja-Wyszomirska Micha ł Macech Monika Kolanowska Marek Krawczyk S ławomir Nazarewski Anna W ójcicka Jolanta Ma łyszko Source Type: research

Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation
Ann Transplant. 2023 Aug 15;28:e939750. doi: 10.12659/AOT.939750.ABSTRACTA number types of extracellular DNA (eg, cell-free, cfDNA) circulate in human blood, including mitochondrial, transcriptome, and regulatory DNA, usually at low concentrations. Larger amounts of cfDNA appear in any inflammatory condition, including organ damage due to a variety of reasons. The role of cfDNA in solid organ transplantation is discussed in this review as a valuable additional tool in the standard of care of transplant patients. Post-transplant monitoring requires the use of high-quality biomarkers for early detection of graft damage or re...
Source: Annals of Transplantation - August 15, 2023 Category: Transplant Surgery Authors: Joanna Raszeja-Wyszomirska Micha ł Macech Monika Kolanowska Marek Krawczyk S ławomir Nazarewski Anna W ójcicka Jolanta Ma łyszko Source Type: research

Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation
Ann Transplant. 2023 Aug 15;28:e939750. doi: 10.12659/AOT.939750.ABSTRACTA number types of extracellular DNA (eg, cell-free, cfDNA) circulate in human blood, including mitochondrial, transcriptome, and regulatory DNA, usually at low concentrations. Larger amounts of cfDNA appear in any inflammatory condition, including organ damage due to a variety of reasons. The role of cfDNA in solid organ transplantation is discussed in this review as a valuable additional tool in the standard of care of transplant patients. Post-transplant monitoring requires the use of high-quality biomarkers for early detection of graft damage or re...
Source: Annals of Transplantation - August 15, 2023 Category: Transplant Surgery Authors: Joanna Raszeja-Wyszomirska Micha ł Macech Monika Kolanowska Marek Krawczyk S ławomir Nazarewski Anna W ójcicka Jolanta Ma łyszko Source Type: research

Graft and Patient Survival in Kidney Transplant with Deceased Donor Using KDRI (Kidney Donor Risk Index), KDPI (Kidney Donor Profile Index), and EPTS (Estimated Post-Transplant Survival) in Colombia
CONCLUSIONS Our study represents the initial evaluation of the usefulness of these indices in Colombia. Our results suggest that KDRI, KDPI, and EPTS may serve as valuable tools for kidney allocation in our setting. Further research with larger sample sizes is necessary to validate these indices in our population.PMID:37525450 | PMC:PMC10403991 | DOI:10.12659/AOT.940522 (Source: Annals of Transplantation)
Source: Annals of Transplantation - August 1, 2023 Category: Transplant Surgery Authors: Anabel Vanin A Luis Alfonso Valderrama Cometa Carlos Fernando Acu ña Roldan Norman A Alhajj Carlos Juli án Devia Santacruz Source Type: research

Graft and Patient Survival in Kidney Transplant with Deceased Donor Using KDRI (Kidney Donor Risk Index), KDPI (Kidney Donor Profile Index), and EPTS (Estimated Post-Transplant Survival) in Colombia
CONCLUSIONS Our study represents the initial evaluation of the usefulness of these indices in Colombia. Our results suggest that KDRI, KDPI, and EPTS may serve as valuable tools for kidney allocation in our setting. Further research with larger sample sizes is necessary to validate these indices in our population.PMID:37525450 | PMC:PMC10403991 | DOI:10.12659/AOT.940522 (Source: Annals of Transplantation)
Source: Annals of Transplantation - August 1, 2023 Category: Transplant Surgery Authors: Anabel Vanin A Luis Alfonso Valderrama Cometa Carlos Fernando Acu ña Roldan Norman A Alhajj Carlos Juli án Devia Santacruz Source Type: research

Graft and Patient Survival in Kidney Transplant with Deceased Donor Using KDRI (Kidney Donor Risk Index), KDPI (Kidney Donor Profile Index), and EPTS (Estimated Post-Transplant Survival) in Colombia
CONCLUSIONS Our study represents the initial evaluation of the usefulness of these indices in Colombia. Our results suggest that KDRI, KDPI, and EPTS may serve as valuable tools for kidney allocation in our setting. Further research with larger sample sizes is necessary to validate these indices in our population.PMID:37525450 | PMC:PMC10403991 | DOI:10.12659/AOT.940522 (Source: Annals of Transplantation)
Source: Annals of Transplantation - August 1, 2023 Category: Transplant Surgery Authors: Anabel Vanin A Luis Alfonso Valderrama Cometa Carlos Fernando Acu ña Roldan Norman A Alhajj Carlos Juli án Devia Santacruz Source Type: research