Dietary inflammatory index after liver transplantion: associated effects and long-term outcomes
We examined the dietary inflammatory potential in patients who underwent liver transplantation (LTx), associated factors and its relationship with clinical outcomes ten years after the initial evaluation. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - April 8, 2024 Category: Nutrition Authors: Cristina de Almeida Hott, B árbara Chaves Santos, James R. Hebert, Longgang Zhao, Michael D. Wirth, Eduardo Garcia Vilela, Lucilene Rezende Anastácio Source Type: research
Nephronophthisis 13 caused by WDR19 variants with pancytopenia: case report
We present a case of nephronophthisis 13 that resulted fromWDR19 variants. The patient, a nine-year-old Japanese boy, had detection of mild proteinuria during a school urine screening. Urinalysis revealed mild proteinuria without hematuria. Blood tests indicated pancytopenia, mild elevation of liver enzymes, and kidney dysfunction. Ultrasound examination disclosed hepatosplenomegaly. Abdominal computed tomography and bone marrow assessments ruled out malignant tumors. Subsequent kidney and liver biopsies suggested nephronophthisis and congenital hepatic fibrosis. Furthermore, comprehensive genetic analysis through next-gen...
Source: CEN Case Reports - April 8, 2024 Category: Urology & Nephrology Source Type: research
Evolution of transplant oncology indications: a single-institution experience over 40 years
AbstractLiver transplantation (LT) for uncommon tumoral indications has changed across the decades, with impaired results reported in the first historical series mainly for non-tumoral-related causes. Recently, renewed interest in liver transplant oncology has been reported. The study aims to analyze a mono-center experience exploring the evolution and the impact on patient survival of LT in uncommon tumoral indications. A retrospective analysis of 851 LT performed during 1982 –2023 was investigated. 33/851 (3.9%) uncommon tumoral indications were reported: hepatocellular carcinoma (HCC) on non-cirrhotic liver (n = 1...
Source: Updates in Surgery - April 8, 2024 Category: Surgery Source Type: research
Clinical outcomes of liver transplantation in human immunodeficiency virus/hepatitis B virus coinfected patients in China
Highly active antiretroviral therapy (HAART) has been able to improve the immune system function and survival of human immunodeficiency virus (HIV) patients. However, Patients coinfected with HIV and hepatitis... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 8, 2024 Category: Infectious Diseases Authors: Jianxin Tang, Ruihui Weng, Taishi Fang, Kangjun Zhang, Xu Yan, Xin Jin, Linjie Xie and Dong Zhao Tags: Research Source Type: research
Cancers, Vol. 16, Pages 1422: The Current and Prospective Adjuvant Therapies for Hepatocellular Carcinoma
Wang
Hepatocellular carcinoma (HCC) stands as the most prevalent form of primary liver cancer and is highly invasive and easily recurs. For HCC, chemotherapy shows limited effect. The gold standard for HCC treatment includes curative surgical resection or liver transplantation. However, the recurrence rate at 5 years after liver resection is estimated at approximately 70% and even at 5 years after liver transplantation, it is 20%. Therefore, improving survival outcomes after curative surgical resection of liver cancer is crucial. This review highlights the importance of identifying risk factors for HCC recurrence foll...
Source: Cancers - April 6, 2024 Category: Cancer & Oncology Authors: Jeng-Shiun Du Shih-Hsien Hsu Shen-Nien Wang Tags: Review Source Type: research
Therapeutic endoscopy: Recent updates and future directions
The landscape of therapeutic endoscopy has undergone a remarkable evolution over the past few decades, carving out a niche that merges innovative technology with advanced clinical practice. As we venture further into the 21st century, the horizon of this field continues to expand, driven by rapid advancements in technology and a deeper understanding of gastrointestinal pathology. This review article aims to shed light on the recent advances and future trajectories of therapeutic endoscopy, focusing on pivotal areas such as third space endoscopy, endoscopic resection techniques, artificial endoscopy, endoscopic ultrasound (...
Source: Digestive and Liver Disease - April 6, 2024 Category: Gastroenterology Authors: Zaheer Nabi, D. Nageshwar Reddy Tags: Review Article Source Type: research
The Current Status of Organ Recovery Surgeon Remuneration in the United States
AbstractPurpose of ReviewRemuneration for surgeons who procure organs for transplantation from deceased donors is highly variable throughout the country and not standardized by the Centers for Medicare& Medicaid Services (CMS). CMS does not grant formal relative value units (RVUs) for organ recoveries but some transplant centers award “non-standardized” RVUs in an ad hoc fashion.Recent FindingsA REDCap survey was sent out by the Business Practice Committee of the American Society of Transplant Surgeons to understand the practices of individual transplant centers regarding payment for transplant-related procedures. ...
Source: Current Transplantation Reports - April 6, 2024 Category: Transplant Surgery Source Type: research
From liver to hormones: The endocrine consequences of cirrhosis
This article provides a comprehensive review of the epidemiology, pathophysiology, diagnosis, and treatment of endocrine disturbances in liver cirrhosis. The review was conducted using the PubMed/Medline, EMBASE, and Scielo databases, encompassing 172 articles. Liver cirrhosis is associated with endocrine disturbances, including diabetes, hypoglycemia, sarcopenia, thyroid dysfunction, hypogonadotropic hypogonadism, bone disease, adrenal insufficiency, growth hormone dysfunction, and secondary hyperaldosteronism. The optimal tools for diagnosing diabetes and detecting hypoglycemia are the oral glucose tolerance test and con...
Source: World Journal of Gastroenterology : WJG - April 5, 2024 Category: Gastroenterology Authors: Juan Eduardo Quiroz-Aldave Elman Rolando Gamarra-Osorio Mar ía Del Carmen Durand-Vásquez Luciana Del Pilar Rafael-Robles Jhean Gabriel Gonz áles-Yovera Mar ía Alejandra Quispe-Flores Luis Alberto Concepci ón-Urteaga Alejandro Rom án-González Jos é Source Type: research
National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma
World J Gastroenterol. 2024 Mar 7;30(9):1018-1042. doi: 10.3748/wjg.v30.i9.1018.ABSTRACTA consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26, 2023, at the Pakistan Kidney and Liver Institute & Research Centre (PKLI & RC) after initial consultations with the experts. The Pakistan Society for the Study of Liver Diseases (PSSLD) and PKLI & RC jointly organised this meeting. This effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma (hCCA). The consensus was that hCCA is a comple...
Source: World Journal of Gastroenterology : WJG - April 5, 2024 Category: Gastroenterology Authors: Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Source Type: research
Role of albumin-bilirubin score in non-malignant liver disease
This article presents a review of the application of ALBI scores in various non-malignant liver diseases.PMID:38577181 | PMC:PMC10989493 | DOI:10.3748/wjg.v30.i9.999 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 5, 2024 Category: Gastroenterology Authors: Shi-Xue Xu Fan Yang Nan Ge Jin-Tao Guo Si-Yu Sun Source Type: research
From liver to hormones: The endocrine consequences of cirrhosis
This article provides a comprehensive review of the epidemiology, pathophysiology, diagnosis, and treatment of endocrine disturbances in liver cirrhosis. The review was conducted using the PubMed/Medline, EMBASE, and Scielo databases, encompassing 172 articles. Liver cirrhosis is associated with endocrine disturbances, including diabetes, hypoglycemia, sarcopenia, thyroid dysfunction, hypogonadotropic hypogonadism, bone disease, adrenal insufficiency, growth hormone dysfunction, and secondary hyperaldosteronism. The optimal tools for diagnosing diabetes and detecting hypoglycemia are the oral glucose tolerance test and con...
Source: World Journal of Gastroenterology - April 5, 2024 Category: Gastroenterology Authors: Juan Eduardo Quiroz-Aldave Elman Rolando Gamarra-Osorio Mar ía Del Carmen Durand-Vásquez Luciana Del Pilar Rafael-Robles Jhean Gabriel Gonz áles-Yovera Mar ía Alejandra Quispe-Flores Luis Alberto Concepci ón-Urteaga Alejandro Rom án-González Jos é Source Type: research
National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma
World J Gastroenterol. 2024 Mar 7;30(9):1018-1042. doi: 10.3748/wjg.v30.i9.1018.ABSTRACTA consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26, 2023, at the Pakistan Kidney and Liver Institute & Research Centre (PKLI & RC) after initial consultations with the experts. The Pakistan Society for the Study of Liver Diseases (PSSLD) and PKLI & RC jointly organised this meeting. This effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma (hCCA). The consensus was that hCCA is a comple...
Source: World Journal of Gastroenterology - April 5, 2024 Category: Gastroenterology Authors: Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Source Type: research
Role of albumin-bilirubin score in non-malignant liver disease
This article presents a review of the application of ALBI scores in various non-malignant liver diseases.PMID:38577181 | PMC:PMC10989493 | DOI:10.3748/wjg.v30.i9.999 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 5, 2024 Category: Gastroenterology Authors: Shi-Xue Xu Fan Yang Nan Ge Jin-Tao Guo Si-Yu Sun Source Type: research
