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Effect of Direct-Acting Antivirals on future occurrence of hepatocellular carcinoma in compensated cirrhotic patients
The achievement of high rates of sustained virological response (SVR) with direct-acting antivirals (DAAs) in hepatitis C virus (HCV) infected patients will reduce decompensating terminal events. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 18, 2017 Category: Gastroenterology Authors: Alessandro Cucchetti, Gennaro D ’Amico, Franco Trevisani, Maria Cristina Morelli, Alessandro Vitale, Antonio Daniele Pinna, Matteo Cescon, from the Special Interest Group onHepatocellular carcinoma and new anti HCV therapie of the Italian Association fo Tags: Liver, Pancreas and Biliary Tract Source Type: research

Post-polypectomy bleeding after colonoscopy on uninterrupted aspirin/non steroideal antiflammatory drugs: systematic review and meta-analysis
The aim of this systematic review and meta-analysis was to assess the risk of post-polypectomy bleeding (PPB) in patients that underwent colorectal polypectomy and exposed to ASA/NSAIDs. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 18, 2017 Category: Gastroenterology Authors: Flavia Pig ò, Helga Bertani, Giuseppe Grande, Abate Federica, Sara Vavassori, Rita Luisa Conigliaro Tags: Review Article Source Type: research

Quadruple, sequential, and concomitant first-line therapies for H. pylori eradication: a prospective, randomized study.
Current Italian guidelines recommend 10-day bismuth-based or bismuth-free (sequential and concomitant) regimens for first-line H. pylori eradication. However, comparison among these regimens is lacking in our country. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 18, 2017 Category: Gastroenterology Authors: Vincenzo De Francesco, Stefano Pontone, Annamaria Bellesia, Gaetano Serviddio, Cristina Panetta, Rossella Palma, Angelo Zullo Tags: Alimentary Tract Source Type: research

Unsuspected schwannomas of the gallbladder
Schwannomas are neurogenic tumors that originate from the nerve sheaths of the peripheral nerves. Schwannomas arising from the gallbladder are extremely rare. In the present case, we report a 70-year-old man, who was admitted the hospital because of epigastric pain and jaundice. Based on the evidence of blood tests, ultrasonography and magnetic resonance imaging, a diagnosis of cholecystitis and cholangitis caused by stone was considered preoperatively. He underwent laparoscopic cholecystectomy and laparoscopic common bile duct exploration. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 17, 2017 Category: Gastroenterology Authors: Yi-Xin Lin, Zi-Ming Liu, Yi-Yun Fu, Qian-Bin Jia Tags: Image of the Month Source Type: research

Editorial Board
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 16, 2017 Category: Gastroenterology Source Type: research

Tenofovir, entecavir, and lamivudine in patients with severe acute exacerbation and hepatic decompensation of chronic hepatitis B
To compare the efficacy of and mortality after lamivudine (LAM), tenofovir (TDF), and entecavir (ETV) treatment in patients with severe acute chronic hepatitis B (CHB) exacerbation. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 15, 2017 Category: Gastroenterology Authors: Jung Gil Park, Yu Rim Lee, Soo Young Park, Heon Ju Lee, Won Young Tak, Young Oh Kweon, Se Young Jang, Jae Min Chun, Young Seok Han, Keun Hur, Hye Won Lee, Min Kyu Kang Tags: Liver, Pancreas and Biliary Tract Source Type: research

Transmural healing in crohn ́s disease: beyond mural findings
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 13, 2017 Category: Gastroenterology Authors: S. Lopes, P. Andrade, R. Cunha, F. Magro Tags: Letter to the Editor Source Type: research

ERC vs. direct cholangioscopy: dawn of a new reference standard
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 13, 2017 Category: Gastroenterology Authors: Vincent Zimmer Tags: Image of the Month Source Type: research

Transglutaminase 6 antibodies are not yet mainstream in Neuro- Coeliac Disease
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 13, 2017 Category: Gastroenterology Authors: C.J.J. Mulder, M.D. Rouvroye, A-M. van Dam Tags: Commentary Source Type: research

Depression and anxiety in caregivers of patients with celiac disease
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 11, 2017 Category: Gastroenterology Authors: Tomoyuki Kawada Tags: Correspondence Source Type: research

Role of diuretics in the harmful effects of beta blockers in patients with ascites. Author ’s reply
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 11, 2017 Category: Gastroenterology Authors: Mattias Mandorfer, Thomas Reiberger Tags: Correspondence Source Type: research

Transmural healing in crohn ’s disease: beyond mural findings − authors’ reply
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 11, 2017 Category: Gastroenterology Authors: Fabiana Castiglione, Anna Testa, Nicola Imperatore, Antonio Rispo Tags: Correspondence Source Type: research

Donor diabetes and prolonged cold ischemia time increase the risk of graft failure after liver transplant: should we need a redefinition of the donor risk index?
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 10, 2017 Category: Gastroenterology Authors: Davide GHINOLFI, LAI Quirino, Paolo DE SIMONE Tags: Correspondence Source Type: research

Quality of care indicators in inflammatory bowel disease in a tertiary referral center with open access and objective assessment policies
In the management of inflammatory bowel diseases, there is considerable variation in quality of care. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 9, 2017 Category: Gastroenterology Authors: Lorant Gonczi, Zsuzsanna Kurti, Petra Anna Golovics, Barbara Dorottya Lovasz, Orsolya Menyhart, Anna Seres, Liza Dalma Sumegi, Alexander Gal, Akos Ilias, Papp Janos, Krisztina Barbara Gecse, Talat Bessisow, Waqqas Afif, Alain Bitton, Vegh Zsuzsanna, Peter Tags: Alimentary Tract Source Type: research

Spleen stiffness is positively correlated with HVPG and decreases significantly after TIPS implantation
Transjugular intrahepatic portosystemic shunt (TIPS) is indicated in patients with decompensated portal hypertension (PH). Hepatic venous pressure gradient (HVPG) is considered gold standard for assessment of PH. Because HVPG measurement is invasive, non-invasive methods for evaluating severity of PH are warranted. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 9, 2017 Category: Gastroenterology Authors: Matthias Buechter, Paul Manka, Jens M. Theysohn, Marcus Reinboldt, Ali Canbay, Alisan Kahraman Tags: Liver, Pancreas and Biliary Tract Source Type: research

Transient elastography to assess liver stiffness in patients with inflammatory bowel disease
Liver injury during inflammatory bowel disease (IBD) is primarily diagnosed by liver biopsy, which has a small but serious risk of severe complications. The aim of this study was to assess liver stiffness, and subsequently the prevalence and associations of liver fibrosis in IBD patients with thiopurine therapy and other clinical factors, by using transient elastography (TE). (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 6, 2017 Category: Gastroenterology Authors: Berrie Meijer, Charlotte K. van Everdingen, Dewkoemar Ramsoekh, Catherine Stedman, Christopher M.A. Frampton, Chris J.J. Mulder, Gerd Bouma, Nanne K.H. de Boer, Richard B. Gearry Tags: Liver, Pancreas and Biliary Tract Source Type: research

Gastric Preparation for Magnetically Controlled Capsule Endoscopy: A Prospective, Randomized Single-Blinded Controlled Trial
Magnetically Controlled Capsule Endoscopy (MCE) is a novel technique for which there is no agreed gastric preparation. We aimed to determine an optimal standardized gastric preparation regimen. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 6, 2017 Category: Gastroenterology Authors: Shu-Guang Zhu, Yang-Yang Qian, Xin-Ying Tang, Qian-Qian Zhu, Wei Zhou, Han Du, Wei An, Xiao-Ju Su, An-Jing Zhao, Hey-Long Ching, Mark Edward McAlindon, Zhao-Shen Li, Zhuan Liao Tags: Digestive Endoscopy Source Type: research

Is histologic remission in ulcerative colitis ready for prime time?
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 6, 2017 Category: Gastroenterology Authors: Jordi Guardiola, Claudia Arajol, Alessandro Armuzzi Tags: Commentary Source Type: research

Small bowel adenocarcinoma: French Intergroup Clinical Practice Guidelines for diagnosis, treatments and follow-up (SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO)
This document is a summary of the French Intergroup guidelines regarding the management of small bowel adenocarcinoma published in October 2016. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 6, 2017 Category: Gastroenterology Authors: Christophe Locher, Blaise Batumona, Pauline Afchain, Nicolas Carr ère, Emmanuelle Samalin, Christophe Cellier, Thomas Aparicio, Yves Becouarn, Laurent Bedenne, Pierre Michel, Yann Parc, Marc Pocard, Benoit Chibaudel, Olivier Bouché, on behalf of the Th Tags: Review Article Source Type: research

Immediate Postoperative Fibrosis-4 Predicts Postoperative Liver Failure for Patients with Hepatocellular Carcinoma Undergoing Curative Surgery
Postoperative liver failure remains the main complication and predominant cause of hepatectomy-related mortality for patients undergoing liver resection. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 5, 2017 Category: Gastroenterology Authors: Haiqing Wang, Lei Li, Wentao Bo, Aixiang Liu, Xielin Feng, Yong Hu, Lang Tian, Hui Zhang, Xiaoli Tang, Lixia Zhang, Mingyi Zhang Tags: Liver, Pancreas and Biliary Tract Source Type: research

Celiac disease or positive tissue transglutaminase antibodies in patients undergoing renal biopsies
An association between celiac disease and renal diseases has been suggested, but the results are controversial. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 5, 2017 Category: Gastroenterology Authors: Rakel Nurmi, Martti Metso, Ilkka P örsti, Onni Niemelä, Heini Huhtala, Jukka Mustonen, Katri Kaukinen, Satu Mäkelä Tags: Alimentary Tract Source Type: research

The mycobiome: Role in health and disease, and as a potential probiotic target in gastrointestinal disease
The human gastrointestinal (GI) tract is home to trillions of microorganisms, some beneficial and others potentially harmful. Recent advances in science have allowed us to identify the multitude of organisms inhabiting the GI tract and parse out those that play a role in inflammatory bowel disease (IBD). Unfortunately, most research has focused on studying only the bacteria while ,overlooking a key player, fungus. In order to address this issue, we have focused our efforts on studying the fungal community in the GI tract known as the mycobiome. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 4, 2017 Category: Gastroenterology Authors: Christopher L. Hager, Mahmoud A. Ghannoum Tags: Review Article Source Type: research

Pancreatic duct cytology, an underused diagnostic tool
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - October 3, 2017 Category: Gastroenterology Authors: Pedro Pereira, Armando Peixoto, Eduardo Rodrigues-Pinto, Guilherme Macedo Tags: Correspondence Source Type: research

Obstructive sleep apnea is predictive of worse hospital outcomes in hospitalizations with acute pancreatitis in obese patients
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 27, 2017 Category: Gastroenterology Authors: Sanjay Bhandari, Madhavi Reddy, Ghulamullah Shahzad Tags: Correspondence Source Type: research

Editorial Board
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 23, 2017 Category: Gastroenterology Source Type: research

SUVmax AFTER (18)FLUORO-DEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY: A TOOL TO DEFINE TREATMENT STRATEGIES IN PANCREATIC CANCER
(18)fluoro-deoxyglucose positron emission tomography/computed tomography (18FDG-PET/CT) might be a useful tool in the management of pancreatic ductal adenocarcinoma (PDAC). (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 22, 2017 Category: Gastroenterology Authors: Ilaria Pergolini, Stefano Crippa, Matteo Salgarello, Giulio Belfiori, Stefano Partelli, Giacomo Ruffo, Alessandro Pucci, Giuseppe Zamboni, Massimo Falconi Tags: Oncology Source Type: research

Clinical outcome after biliary drainage for metastatic colorectal cancer: survival analysis and prognostic factors
Biliary obstruction secondary to colorectal cancer liver metastases is associated with a poor prognosis especially when chemotherapy cannot be re-started. The aim of this study was to determine the survival after biliary drainage and the associated prognostic factors. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 21, 2017 Category: Gastroenterology Authors: F Sellier, E Bories, C Sibertin-Blanc, K Griffiths, L Dahan, M Giovannini, J Gaudart, JF Seitz, R Laugier, P Grandval Tags: Liver, Pancreas and Biliary Tract Source Type: research

A model of an inflammatory bowel disease population-based registry: The Forl ì experience (1993–2013)
The article presents a population-based registry designed to estimate incidence and prevalence of inflammatory bowel disease (IBD) in the area of Forl ì (north-eastern Italy). (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 20, 2017 Category: Gastroenterology Authors: Daniela Valpiani, Ilaria Manzi, Marina Mercuriali, Orietta Giuliani, Alessandra Ravaioli, Americo Colamartini, Lauro Bucchi, Fabio Falcini, Enrico Ricci Tags: Alimentary Tract Source Type: research

A model of an inflammatory bowel disease population-based registry: the Forl ì experience (1993-2013)
The article presents a population-based registry designed to estimate incidence and prevalence of inflammatory bowel disease (IBD) in the area of Forl ì (north-eastern Italy). (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 20, 2017 Category: Gastroenterology Authors: Daniela Valpiani, Ilaria Manzi, Marina Mercuriali, Orietta Giuliani, Alessandra Ravaioli, Americo Colamartini, Lauro Bucchi, Fabio Falcini, Enrico Ricci Tags: Alimentary Tract Source Type: research

Histological healing beyond endoscopic healing in ulcerative colitis: Shall we target the “ultra-deep” remission?
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 15, 2017 Category: Gastroenterology Authors: Konstantinos H. Katsanos, Konstantinos Papamichael, Dimitrios K. Christodoulou, Adam S. Cheifetz Tags: Commentary Source Type: research

Role of diuretics in the harmful effects of beta blockers in patients with ascites
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 12, 2017 Category: Gastroenterology Authors: Pramod Kumar Tags: Correspondence Source Type: research

Life threatening hemobilia after endoscopic retrograde cholangiopancreatography (ERCP)
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 11, 2017 Category: Gastroenterology Authors: Ihab I.El Hajj, Stuart Sherman, Maximilian Pyko, Glen A. Lehman Tags: Digestive Endoscopy Source Type: research

Screening, prophylaxis and counselling before the start of biological therapies: a practical approach focused on IBD patients
The standard of care in the management of immune-mediated inflammatory conditions relies on immunomodulators, glucocorticoids, and biologicals (including anti-tumour necrosis factor −α and other monoclonal antibodies). These agents have an overall favourable benefit/risk ratio; however, they modulate the immune response as part of their mechanisms of action, and therefore they may increase the risk of developing infections, particularly in older patients or in patients with concomitant corticosteroids. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 11, 2017 Category: Gastroenterology Authors: C ândida Abreu, António Sarmento, Fernando Magro Tags: Review Article Source Type: research

Acute histological inflammatory activity is associated with clinical relapse in patients with ulcerative colitis in clinical and endoscopic remission.
It has been suggested that acute histological activity has a prognostic value in the outcome of ulcerative colitis (UC) patients in clinical and endoscopic remission. Our aim was to assess the role of histology as a risk factor for clinical relapse (CR) in patients in both clinical and endoscopic remission. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 8, 2017 Category: Gastroenterology Authors: Margalida Calafat, Triana Lobat ón, Alba Hernández-Gallego, Míriam Mañosa, Paola Torres, Fiorella Cañete, Eduard Cabré, Isabel Ojanguren, Eugeni Domènech Tags: Alimentary Tract Source Type: research

Clinical profile of cannabis-associated acute pancreatitis
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 6, 2017 Category: Gastroenterology Authors: Adrian Culetto, Barbara Bournet, Louis Buscail Tags: Correspondence Source Type: research

Endoscopic ultrasonography in chronic asymptomatic pancreatic hyperenzymemia: why not?
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 6, 2017 Category: Gastroenterology Authors: Filippo Antonini, Giampiero Macarri, Raffaele Pezzilli Tags: Correspondence Source Type: research

Early closure of fistula using neo-adjuvant intra-arterial chemotherapy in locally advanced anal cancer
Locally advanced anal cancer patients, especially with T4 disease and fistula, have a dismal prognosis. Neo-adjuvant intra-arterial chemotherapy before standard chemoradiation has been shown to be promising in this setting. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 5, 2017 Category: Gastroenterology Authors: Wulfran Cacheux, Thibaud Koessler, Giacomo Puppa, Eugenio Fernandez, Lisa Ho, Pierre-Yves Dietrich, Thomas Zilli, Abdelkarim Said Allal, Bruno Roche, Frederic Ris, Arnaud Roth Tags: Oncology Source Type: research

Microspheres in gall bladder
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 4, 2017 Category: Gastroenterology Authors: THIAGARAJAH BALAMURUGAN, FUAD HUSSAIN, IZHAR N. BAGWAN Tags: Correspondence Source Type: research

Italian Society of Digestive Endoscopy (SIED) Position Paper on the Non-Anaesthesiologist Administration of Propofol for Gastrointestinal Endoscopy
Propofol sedation by non-anesthesiologists in GI endoscopy, despite generally considered a safe procedure, is still a matter of debate. Benefits of propofol sedation include rapid onset of action, greater patient comfort and fast recovery with prompt discharge from the endoscopy unit.The use of propofol for sedation in GI endoscopy, preceded by dedicated training courses, has been approved by several Anaesthesiologist and Gastroenterologist societies but an Italian Position Paper taking into account the Italian law is lacking. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 4, 2017 Category: Gastroenterology Authors: Rita Conigliaro, Lorella Fanti, Mauro Manno, Piero Brosolo, Italian Society of Digestive Endoscopy (SIED) Sedation Group Tags: Digestive Endoscopy Source Type: research

Alcohol consumption survey in an outpatient center of gastroenterology in southern Italy
Background: Italy ranks first among the European countries in terms of wine production and tenth for annual pro-capita alcohol consumption. However, there are noteworthy regional differences and in particular between northern and southern regions. Few studies have analysed the alcohol consumption in different social contexts in order to better understand the relationship between environmental, cultural, and personal variables. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 1, 2017 Category: Gastroenterology Authors: L. Abenavoli, P.H. Guzzi, F. Luzza, A. De Lorenzo, G. Addolorato Tags: OC 1 Source Type: research

Hospital dismissal data sheets on alcoholic liver diseases into three first aid divisions: A southern Italy survey
In 2010, the Health World Organisation identified alcohol as one of the prevalent evitable risk's factors in the development of liver and systemic diseases. Epidemiological data represent essential instruments to plan and realize prevention's strategies and to reduce detrimental alcohol consumption. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 1, 2017 Category: Gastroenterology Authors: M. Dallio, G.G. Caprio, V. Ormando, F. Paladino, C. Toscano, G. Cotticelli, C. Loguercio, A. Federico Tags: OC 2 Source Type: research

Hospital admissions for alcoholic and not alcoholic liver cirrhosis in Sicily (2007/2016)
Introduction: The leading causes of cirrhosis in Italy are alcohol intake, B and C Hepatitis viruses and metabolic syndrome. According to the Italian Institute of Statistics (ISTAT) the mortality rate for liver cirrhosis has decreased from 34.5 (1980) to 10.8/100,000 (2012). This favourable trend is due to the improvement of treatments and to a decreasing role of HBV and HCV infections. Only selected hospital based-series have showed this reduction for HBV and HCV related cirrhosis. These studies may be biased by patient selection. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 1, 2017 Category: Gastroenterology Authors: G. Butera, G. Dardanoni, G. Fantaci, S. Arnone, M. Maringhini, A. Maringhini Tags: OC 3 Source Type: research

Blood alcohol concentration changes in laboratory samples during refrigerated storage
Background: Stability of blood alcohol concentration (BAC) in laboratory samples is very important when it is necessary to perform repeated analyses. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 1, 2017 Category: Gastroenterology Authors: L. Abenavoli, M. Maletin, D. Stojic, S. Brkic, G. Stojiljkovic Tags: OC 4 Source Type: research

Early liver transplantation for severe acute alcoholic hepatitis: Pilot program in a single transplant centre in Italy
Background: Acute alcoholic hepatitis (AAH) is a clinical syndrome characterized by high mortality rates. There is increasing evidence that early liver transplantation (LT), performed within strict and standardized protocols, can improve survival. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 1, 2017 Category: Gastroenterology Authors: G. Germani, E. Romandini, A. Ferrarese, A. Zanetto, M. Gambato, M. Senzolo, F.P. Russo, F. D ’Amico, U. Cillo, P. Burra Tags: OC 5 Source Type: research

Nutritional assessment in alcohol related disorders: Results from a cross sectional study on hospitalized patients
Introduction: Malnutrition is recognized as a frequent complication in alcoholic liver disease. Recently, several malnutrition screening and assessment tools have been recognized in clinical practice [1]. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 1, 2017 Category: Gastroenterology Authors: E. Rinninella, M. Cintoni, L. Basso, S. Leone, G. Egidi, G. Vassallo, M. Antonelli, C. Tarli, G. Addolorato, A. Gasbarrini, G.A.D. Miggiano, M.C. Mele Tags: OC 6 Source Type: research

Cardiovascular risk assessment in alcoholic liver disease: A pilot study
Chronic alcohol abuse is a leading cause of cirrhosis, but is also associated with increased cardiovascular mortality. However, scant information is available on the determinants of atherosclerotic and cardiac disease in individuals with alcohol abuse. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 1, 2017 Category: Gastroenterology Authors: M. Porzio, G. Pisano, G. Periti, V. Borroni, S. Pelusi, M. Milano, E. Fatta, C. Bertelli, P. Dongiovanni, A.L. Fracanzani, S. Fargion, L. Valenti Tags: OC 7 Source Type: research

Deep transcranial magnetic stimulation of the dorsolateral prefrontal cortex in alcohol use disorder patients: Effects on dopamine transporter availability and alcohol intake
Repetitive Transcranial Magnetic Stimulation (rTMS) of the dorsolateral prefrontal cortex may affect neuro-adaptations associated with alcohol use disorder (AUD), potentially influencing craving and alcohol intake. We investigated alcohol intake and dopamine transporter (DAT) availability by Single Photon Emission Computed Tomography (SPECT) in the striatum of AUD patients before and after deep rTMS. Fourteen patients underwent baseline clinical and SPECT assessment. Eleven out of fourteen patients were randomized into two groups for the REAL (n. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 1, 2017 Category: Gastroenterology Authors: M. Antonelli, L. Sestito, G.A. Vassallo, M.M. Rando, C. Tarli, C. Mosoni, A. Mirijello, A. Ferulli, D. Di Giuda, M. Diana, A. Giordano, A. Gasbarrini, G. Addolorato Tags: OC 8 Source Type: research

Evolution of liver transplantation for alcoholic liver disease: A single center study
Introduction: Alcohol-related liver disease (ALD) is a major indication for Liver Transplantation (LT), both for decompensated disease and for hepatocellular carcinoma (HCC). Recently, LT has been considered a therapeutic option for steroid non-responder Acute Alcoholic Hepatitis (AAH). (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 1, 2017 Category: Gastroenterology Authors: A. Ferrarese, G. Germani, C. Becchetti, A. Zanetto, S. Shalaby, E. Romandini, F.P. Russo, M. Senzolo, M. Gambato, P. Angeli, F. D ’Amico, U. Cillo, P. Burra Tags: OC 9 Source Type: research

Liver transplantation in patients with alcoholic liver disease: A retrospective study
Introduction: Alcoholic liver disease is the most common liver disease in the Western World. Alcohol abstinence represents the gold standard for its treatment. When liver function fails to improve in spite of alcohol abstinence, liver transplantation is the treatment of for end-stage alcoholic liver disease; however, many transplant centers are still reluctant to transplant these group of patients because of the risk of alcohol relapse, recurrence of the primary liver disease and associated post transplant complications. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 1, 2017 Category: Gastroenterology Authors: G.A. Vassallo, C. Tarli, M.M. Rando, C. Mosoni, A. Mirijello, M. Antonelli, L. Sestito, G. Perotti, D. Di Giuda, S. Agnes, A. Grieco, A. Gasbarrini, G. Addolorato, Gemelli OLT Group Tags: OC 10 Source Type: research

The impact of a multidisciplinary team on alcohol recidivism and survival after liver transplantation for alcoholic disease
Introduction: Liver transplant (OLT) for patients with alcoholic abuse (AA) remains controversial, due to the risk of alcohol recidivism after transplantation, which ranges from 10 to 95%. To achieve a long-term post-OLT alcohol abstinence in AA patients, a comprehensive evaluation of the OLT candidate by a multidisciplinary team (MT), to include also a psychologist, a pharmacologist and a psychiatrist, is recommended, coupled with a strict follow-up post-OLT involving the same clinical team. Therefore, starting from 2014 a MT has been created at our Transplant Center in Modena, and a full evaluation from MT has been intro...
Source: Digestive and Liver Disease - September 1, 2017 Category: Gastroenterology Authors: L. Marzi, S. Guerzoni, M. Vandelli, P. Magistri, V. Serra, A. Borghi, V. Bernabucci, E. Villa, F. Di Benedetto, N. De Maria Tags: OC 11 Source Type: research