Artificial intelligence in liver cancer — new tools for research and patient management
Nature Reviews Gastroenterology & Hepatology, Published online: 16 April 2024; doi:10.1038/s41575-024-00919-yArtificial intelligence (AI) is advancing rapidly and is already starting to transform cancer research and care. Here, the authors outline how AI could be incorporated into liver cancer management, highlighting areas with academic, commercial and clinical potential, as well as ongoing progress and pitfalls. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - April 16, 2024 Category: Gastroenterology Authors: Julien Calderaro Laura Žigutytė Daniel Truhn Ariel Jaffe Jakob Nikolas Kather Source Type: research

A crucial Fusobacterium nucleatum clade in colorectal cancer
Nature Reviews Gastroenterology & Hepatology, Published online: 16 April 2024; doi:10.1038/s41575-024-00930-3A crucial Fusobacterium nucleatum clade in colorectal cancer (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - April 16, 2024 Category: Gastroenterology Authors: Katrina Ray Source Type: research

Promoting allyship to support and uplift the LGBTQIA+ community
Nature Reviews Gastroenterology & Hepatology, Published online: 05 April 2024; doi:10.1038/s41575-024-00928-xThe lesbian, gay, bisexual, transgender, queer, intersex and asexual (LGBTQIA+) community navigates a complex social landscape marked by strides in acceptance alongside enduring discrimination. Allies — individuals outside of the LGBTQIA+ spectrum who support and advocate for this community — are paramount, with allyship playing a critical part in influencing the health and well-being of LGBTQIA+ individuals. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - April 5, 2024 Category: Gastroenterology Authors: Daniel J. Huynh Sonali Paul Nikki Duong Source Type: research

The changing metabolic landscape of bile acids – keys to metabolism and immune regulation
Nature Reviews Gastroenterology & Hepatology, Published online: 04 April 2024; doi:10.1038/s41575-024-00914-3Bile acids have important roles in human metabolism and immune regulation. In this Perspective, Dorrestein and colleagues discuss the technologies and data science-related approaches that are improving our understanding of the diversity of bile acids and their multifaceted roles. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - April 4, 2024 Category: Gastroenterology Authors: Ipsita Mohanty Celeste Allaband Helena Mannochio-Russo Yasin El Abiead Lee R. Hagey Rob Knight Pieter C. Dorrestein Source Type: research

Publisher Correction: Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis
Nature Reviews Gastroenterology & Hepatology, Published online: 04 April 2024; doi:10.1038/s41575-024-00929-wPublisher Correction: Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - April 4, 2024 Category: Gastroenterology Authors: Mar ía R. Aburto John F. Cryan Source Type: research

Improving culturally safe engagement with sexual and gender minority populations
Nature Reviews Gastroenterology & Hepatology, Published online: 02 April 2024; doi:10.1038/s41575-024-00927-yCultural safety seeks to remediate health inequities through empowering marginalized and minoritized patient populations, minimizing implicit bias and incorporating social determinants of health into practice. Here, we propose a cultural safety framework to guide communication with patients from sexual and gender minorities. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - April 2, 2024 Category: Gastroenterology Authors: Newsha Nikzad Nikki Duong Sonali Paul Source Type: research

New understanding of hepatobiliary MRI
Nature Reviews Gastroenterology & Hepatology, Published online: 02 April 2024; doi:10.1038/s41575-024-00926-zMagnetic resonance imaging following injection of hepatobiliary contrast agents improves the detection of hepatocellular carcinomas when contrast agent accumulations in tumours and the surrounding pathological liver differ. However, tissue accumulation is poorly investigated, and this Clinical Outlook article highlights experimental data to understand better contrast agent accumulation in human pathological livers. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - April 2, 2024 Category: Gastroenterology Authors: Catherine M. Pastor Val érie Vilgrain Source Type: research

Tackling sorbitol intolerance
Nature Reviews Gastroenterology & Hepatology, Published online: 25 March 2024; doi:10.1038/s41575-024-00921-4Tackling sorbitol intolerance (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - March 25, 2024 Category: Gastroenterology Authors: Maria Papatriantafyllou Source Type: research

Biomarker shows no clinical use in guiding treatment for Crohn’s disease
Nature Reviews Gastroenterology & Hepatology, Published online: 22 March 2024; doi:10.1038/s41575-024-00923-2Biomarker shows no clinical use in guiding treatment for Crohn’s disease (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - March 22, 2024 Category: Gastroenterology Authors: Eleni Kotsiliti Source Type: research

Bacteriophages and host inflammation in IBD
Nature Reviews Gastroenterology & Hepatology, Published online: 22 March 2024; doi:10.1038/s41575-024-00925-0Bacteriophages and host inflammation in IBD (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - March 22, 2024 Category: Gastroenterology Authors: Eleni Kotsiliti Source Type: research

Seladelpar in primary biliary cholangitis
Nature Reviews Gastroenterology & Hepatology, Published online: 22 March 2024; doi:10.1038/s41575-024-00922-3Seladelpar in primary biliary cholangitis (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - March 22, 2024 Category: Gastroenterology Authors: Eleni Kotsiliti Source Type: research

HCC genomic landscape in Chinese individuals
Nature Reviews Gastroenterology & Hepatology, Published online: 22 March 2024; doi:10.1038/s41575-024-00924-1HCC genomic landscape in Chinese individuals (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - March 22, 2024 Category: Gastroenterology Authors: Eleni Kotsiliti Source Type: research

Towards unifying fatty liver nomenclature: a voice from the Middle East and North Africa
Nature Reviews Gastroenterology & Hepatology, Published online: 18 March 2024; doi:10.1038/s41575-024-00918-zFatty liver disease is one of the most common liver diseases in the Middle East and North Africa region, and globally. Unfortunately, there is a lack of awareness regarding this condition. The nomenclature changes for NAFLD (to MAFLD or MASLD) have gained considerable attention in the hepatology community. Here, we present our point of view on this ongoing change and debate. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - March 18, 2024 Category: Gastroenterology Authors: Yasser Fouad Salma Barakat Almoutaz Hashim Hasmik Ghazinyan Source Type: research

Cell senescence in liver diseases: pathological mechanism and theranostic opportunity
Nature Reviews Gastroenterology & Hepatology, Published online: 14 March 2024; doi:10.1038/s41575-024-00913-4Ageing and senescence are major risk factors for liver disease development. This Review provides a comprehensive overview of hepatic senescence, its role in liver disease progression and hepatocellular carcinoma, and discusses potential therapeutic strategies. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - March 14, 2024 Category: Gastroenterology Authors: David Sanfeliu-Redondo Albert Gibert-Ramos Jordi Gracia-Sancho Source Type: research

Future direction of total neoadjuvant therapy for locally advanced rectal cancer
Nature Reviews Gastroenterology & Hepatology, Published online: 14 March 2024; doi:10.1038/s41575-024-00900-9In this article, the authors discuss the use of total neoadjuvant therapy for locally advanced rectal cancer. They highlight ongoing trials and discuss future treatment options, including the potential use of multi-omics and artificial intelligence to facilitate treatment selection and prediction of response. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - March 14, 2024 Category: Gastroenterology Authors: Yoshinori Kagawa J. Joshua Smith Emmanouil Fokas Jun Watanabe Andrea Cercek Florian R. Greten Hideaki Bando Qian Shi Julio Garcia-Aguilar Paul B. Romesser Natally Horvat Hanna Sanoff William Hall Takeshi Kato Claus R ödel Arvind Dasari Takayuki Yoshino Source Type: research