A Prospective Multimodal Education Intervention for Providers Does Not Increase Hepatic Encephalopathy Treatment Rates
ConclusionThis MMEI did not increase HE treatment rates, suggesting that alternative strategies are needed to identify and address barriers to treatment. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 23, 2024 Category: Gastroenterology Source Type: research

Statewide Survey of Primary Care and Subspecialty Providers on Hepatocellular Carcinoma Risk-Stratification and Surveillance Practices
ConclusionsIn this statewide survey, there were great knowledge gaps in HCC surveillance among PCPs and most respondents expressed interest in strategies to increase appropriate HCC surveillance. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 23, 2024 Category: Gastroenterology Source Type: research

Spatial genomics: mapping human steatotic liver disease
Nature Reviews Gastroenterology & Hepatology, Published online: 23 April 2024; doi:10.1038/s41575-024-00915-2This Perspective discusses single-cell and single-nuclei RNA sequencing in metabolic dysfunction-associated steatotic liver disease and explains how our understanding of the pathology of the disease will accelerate following the advances in spatial transcriptomics. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - April 23, 2024 Category: Gastroenterology Authors: Kylie P. Matchett Jasmin Paris Sarah A. Teichmann Neil C. Henderson Source Type: research

Clinical predictive value of Control attenuation parameters in combination with miR-192-5p in patients with acute pancreatitis in nonalcoholic fatty liver disease
CONCLUSIONS: NAFLD exacerbated the progression of AP, and CAP combined with miR-192-5p could predict the severity of AP. Our study may provide more reference for AP disease progression and treatment.PMID:38646989 | DOI:10.5603/ep.98765 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Yang Hu Liang Zhu Ronglai Cao Source Type: research

Excessive Alcohol Use and Alcohol Use Disorders: A Policy Brief of the American College of Physicians
Ann Intern Med. 2024 Apr 23. doi: 10.7326/M23-3434. Online ahead of print.ABSTRACTAlcohol is used by more people in the United States than tobacco, electronic nicotine delivery systems, or illicit drugs. Several health conditions, including cancer, cardiovascular disease, and liver disease, are associated with excessive alcohol use and alcohol use disorder. Nearly 30 million people aged 12 years or older in the United States reported past-year alcohol use disorder in 2022, but-despite its prevalence-alcohol use disorder is undertreated. In this policy brief, the American College of Physicians outlines the health effects of...
Source: Annals of Internal Medicine - April 22, 2024 Category: Internal Medicine Authors: Ryan Crowley David Hilden Micah Beachy Health and Public Policy Committee of the American College of Physicians Source Type: research

Clinical predictive value of Control attenuation parameters in combination with miR-192-5p in patients with acute pancreatitis in nonalcoholic fatty liver disease
CONCLUSIONS: NAFLD exacerbated the progression of AP, and CAP combined with miR-192-5p could predict the severity of AP. Our study may provide more reference for AP disease progression and treatment.PMID:38646989 | DOI:10.5603/ep.98765 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Yang Hu Liang Zhu Ronglai Cao Source Type: research

Excessive Alcohol Use and Alcohol Use Disorders: A Policy Brief of the American College of Physicians
Ann Intern Med. 2024 Apr 23. doi: 10.7326/M23-3434. Online ahead of print.ABSTRACTAlcohol is used by more people in the United States than tobacco, electronic nicotine delivery systems, or illicit drugs. Several health conditions, including cancer, cardiovascular disease, and liver disease, are associated with excessive alcohol use and alcohol use disorder. Nearly 30 million people aged 12 years or older in the United States reported past-year alcohol use disorder in 2022, but-despite its prevalence-alcohol use disorder is undertreated. In this policy brief, the American College of Physicians outlines the health effects of...
Source: Annals of Internal Medicine - April 22, 2024 Category: Internal Medicine Authors: Ryan Crowley David Hilden Micah Beachy Health and Public Policy Committee of the American College of Physicians Source Type: research

Clinical predictive value of Control attenuation parameters in combination with miR-192-5p in patients with acute pancreatitis in nonalcoholic fatty liver disease
CONCLUSIONS: NAFLD exacerbated the progression of AP, and CAP combined with miR-192-5p could predict the severity of AP. Our study may provide more reference for AP disease progression and treatment.PMID:38646989 | DOI:10.5603/ep.98765 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Yang Hu Liang Zhu Ronglai Cao Source Type: research

Excessive Alcohol Use and Alcohol Use Disorders: A Policy Brief of the American College of Physicians
Ann Intern Med. 2024 Apr 23. doi: 10.7326/M23-3434. Online ahead of print.ABSTRACTAlcohol is used by more people in the United States than tobacco, electronic nicotine delivery systems, or illicit drugs. Several health conditions, including cancer, cardiovascular disease, and liver disease, are associated with excessive alcohol use and alcohol use disorder. Nearly 30 million people aged 12 years or older in the United States reported past-year alcohol use disorder in 2022, but-despite its prevalence-alcohol use disorder is undertreated. In this policy brief, the American College of Physicians outlines the health effects of...
Source: Annals of Internal Medicine - April 22, 2024 Category: Internal Medicine Authors: Ryan Crowley David Hilden Micah Beachy Health and Public Policy Committee of the American College of Physicians Source Type: research

Clinical predictive value of Control attenuation parameters in combination with miR-192-5p in patients with acute pancreatitis in nonalcoholic fatty liver disease
CONCLUSIONS: NAFLD exacerbated the progression of AP, and CAP combined with miR-192-5p could predict the severity of AP. Our study may provide more reference for AP disease progression and treatment.PMID:38646989 | DOI:10.5603/ep.98765 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Yang Hu Liang Zhu Ronglai Cao Source Type: research

Excessive Alcohol Use and Alcohol Use Disorders: A Policy Brief of the American College of Physicians
Ann Intern Med. 2024 Apr 23. doi: 10.7326/M23-3434. Online ahead of print.ABSTRACTAlcohol is used by more people in the United States than tobacco, electronic nicotine delivery systems, or illicit drugs. Several health conditions, including cancer, cardiovascular disease, and liver disease, are associated with excessive alcohol use and alcohol use disorder. Nearly 30 million people aged 12 years or older in the United States reported past-year alcohol use disorder in 2022, but-despite its prevalence-alcohol use disorder is undertreated. In this policy brief, the American College of Physicians outlines the health effects of...
Source: Annals of Internal Medicine - April 22, 2024 Category: Internal Medicine Authors: Ryan Crowley David Hilden Micah Beachy Health and Public Policy Committee of the American College of Physicians Source Type: research

Clinical predictive value of Control attenuation parameters in combination with miR-192-5p in patients with acute pancreatitis in nonalcoholic fatty liver disease
CONCLUSIONS: NAFLD exacerbated the progression of AP, and CAP combined with miR-192-5p could predict the severity of AP. Our study may provide more reference for AP disease progression and treatment.PMID:38646989 | DOI:10.5603/ep.98765 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Yang Hu Liang Zhu Ronglai Cao Source Type: research

Total flavonoids of Broussonetia papyrifera alleviate non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signaling pathways
CONCLUSION: Our experiments proved that TFBP has the therapeutic effect in NAFLD, and the activation of Nrf2 and AMPK signaling pathways should make sense.PMID:38649009 | DOI:10.1016/j.bbalip.2024.159497 (Source: Biochimica et Biophysica Acta)
Source: Biochimica et Biophysica Acta - April 22, 2024 Category: Biochemistry Authors: Qi Wang Yunfei Wei Yeling Wang Ziyang Yu Haiyan Qin Lilei Zhao Jiaqi Cheng Bingyu Shen Meiyu Jin Haihua Feng Source Type: research

Hepato-Cardio-Renal Syndrome
Adv Kidney Dis Health. 2024 Mar;31(2):127-132. doi: 10.1053/j.akdh.2023.07.002.ABSTRACTHepatorenal syndrome has conventionally been regarded as a multisystem syndrome in which pathophysiologic pathways that link cirrhosis with impairment in kidney function are followed by dysfunction of several organs such as the heart. The advances in cardiac studies have helped diagnose more subtle cardiac abnormalities that would have otherwise remained unnoticed in a significant subset of patients with advanced liver disease and cirrhosis. Accumulating data suggests that in many instances, the cardiac dysfunction precedes and predicts ...
Source: Adv Data - April 22, 2024 Category: Epidemiology Authors: Abhilash Koratala Frederik Verbrugge Amir Kazory Source Type: research

Excessive Alcohol Use and Alcohol Use Disorders: A Policy Brief of the American College of Physicians
Ann Intern Med. 2024 Apr 23. doi: 10.7326/M23-3434. Online ahead of print.ABSTRACTAlcohol is used by more people in the United States than tobacco, electronic nicotine delivery systems, or illicit drugs. Several health conditions, including cancer, cardiovascular disease, and liver disease, are associated with excessive alcohol use and alcohol use disorder. Nearly 30 million people aged 12 years or older in the United States reported past-year alcohol use disorder in 2022, but-despite its prevalence-alcohol use disorder is undertreated. In this policy brief, the American College of Physicians outlines the health effects of...
Source: Annals of Internal Medicine - April 22, 2024 Category: Internal Medicine Authors: Ryan Crowley David Hilden Micah Beachy Health and Public Policy Committee of the American College of Physicians Source Type: research