Monitoring thyroid function during amiodarone use
Br J Hosp Med (Lond). 2024 Jan 2;85(1):1-5. doi: 10.12968/hmed.2023.0214. Epub 2024 Jan 31.ABSTRACTAmiodarone is an antiarrhythmic drug used to treat cardiac tachyarrhythmias. It has many adverse effects, with thyroid dysfunction one of the most notable. Through various mechanisms, both thyrotoxicosis and hypothyroidism can occur secondary to amiodarone therapy. There are two types of amiodarone-induced thyrotoxicosis: type 1 occurs in those with pre-existing thyroid disease and is treated with thionamide, whereas type 2 occurs in those without and is treated with glucocorticoids. Patients with amiodarone-induced hypothyro...
Source: British Journal of Hospital Medicine - February 1, 2024 Category: Internal Medicine Authors: Priya Sharma Riyad Sheikh Nipuna Siribaddana Abilash Sathyanarayanan Devaka Fernando Vakkat Muraleedharan Source Type: research
Monitoring thyroid function during amiodarone use
Br J Hosp Med (Lond). 2024 Jan 2;85(1):1-5. doi: 10.12968/hmed.2023.0214. Epub 2024 Jan 31.ABSTRACTAmiodarone is an antiarrhythmic drug used to treat cardiac tachyarrhythmias. It has many adverse effects, with thyroid dysfunction one of the most notable. Through various mechanisms, both thyrotoxicosis and hypothyroidism can occur secondary to amiodarone therapy. There are two types of amiodarone-induced thyrotoxicosis: type 1 occurs in those with pre-existing thyroid disease and is treated with thionamide, whereas type 2 occurs in those without and is treated with glucocorticoids. Patients with amiodarone-induced hypothyro...
Source: British Journal of Hospital Medicine - February 1, 2024 Category: Internal Medicine Authors: Priya Sharma Riyad Sheikh Nipuna Siribaddana Abilash Sathyanarayanan Devaka Fernando Vakkat Muraleedharan Source Type: research
Optimizing Levothyroxine Replacement: A Precision Dosage Model for Post-Thyroidectomy Patients
(Source: International Journal of General Medicine)
Source: International Journal of General Medicine - February 1, 2024 Category: General Medicine Tags: International Journal of General Medicine Source Type: research
Impact of levothyroxine therapy for maternal subclinical hypothyroidism on infant ’s neurodevelopment
This study was aimed to evaluate the effect of levothyroxine therapy for SCH and OH on improving offspring ’s neurodevelopment in infancy period in a real-world setting. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 1, 2024 Category: OBGYN Authors: Zhekun Zhao, Huanqiang Zhao, Yu Xiong, Qiongjie Zhou, Xiaotian Li Source Type: research
The effect of different levothyroxine administration regimens on thyroid hormone levels: a systematic review, pairwise, and network meta-analysis
CONCLUSION: The evidence is insufficient to determine the most effective levothyroxine administration regimen for hypothyroidism.SYSTEMATIC REVIEW REGISTRATION: PROSPERO - CRD42021279375.PMID:38294680 | DOI:10.1080/17512433.2024.2313616 (Source: Expert Review of Clinical Pharmacology)
Source: Expert Review of Clinical Pharmacology - January 31, 2024 Category: Drugs & Pharmacology Authors: Bianca Vendruscolo Bianchini Patricia Romualdo de Jesus Renato Gorga Bandeira de Mello Patricia Klarmann Ziegelmann Kristian Bellevue Filion Tatiane da Silva Dal Pizzol Source Type: research
Comparison of pathophysiology in subclinical hyperthyroidism with different etiologies
Endocr J. 2024 Jan 31. doi: 10.1507/endocrj.EJ23-0497. Online ahead of print.ABSTRACTSubclinical hyperthyroidism (SHyper) is defined as normal levels of free thyroxine (fT4) and free triiodothyronine (fT3) with suppressed levels of TSH. Previous studies have reported the individual pathophysiology of endogenous SHyper patients and athyreotic patients receiving TSH suppression therapy with levothyroxine; however, apparently no studies have compared the two conditions. Five-hundred-forty untreated endogenous SHyper patients and 1,024 patients receiving TSH suppression therapy who underwent total thyroidectomy for papillary t...
Source: Endocrine Journal - January 31, 2024 Category: Endocrinology Authors: Hanna Deguchi-Horiuchi Mitsuru Ito Sawako Takahashi Kazuyoshi Kousaka Mako Hisakado Shuji Fukata Takumi Kudo Eijun Nishihara Mitsushige Nishikawa Akira Miyauchi Takashi Akamizu Source Type: research
22-Year-Old Man With Seizures
A 22-year-old man presented to the emergency department (ED) because of recurrent seizures. His medical comorbidities included epilepsy, type 1 diabetes mellitus, and recently diagnosed Hashimoto thyroiditis. His medications included lacosamide, insulin through an insulin pump, and levothyroxine. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - January 31, 2024 Category: Internal Medicine Authors: Priscilla Koirala, Reema K. Tawfiq, David Raslau Tags: Residents ’ clinic Source Type: research
Morning exercise affects the absorption of oral levothyroxine: a single center pilot study
ConclusionsThis is the first study which demonstrates the significant positive effect of morning exercise on the absorption of LT4 tablets. In addition to that, it was also found that as the daily dose of LT4 increases, the percentage decrease of TSH level becomes greater. (Source: Endocrine)
Source: Endocrine - January 27, 2024 Category: Endocrinology Source Type: research
Body composition changes in patients with differentiated thyroid cancer after iodine-131 treatment and short-term levothyroxine replacement and suppression therapy
CONCLUSIONS: After RAI and short-term LT4 supplementation in DTC patients, body composition rapidly and positively changed and was characterized by decreased fat mass and increased BMC and BMD.PMID:38277093 | DOI:10.1007/s42000-024-00528-z (Source: Hormones)
Source: Hormones - January 26, 2024 Category: Endocrinology Authors: Ru Wang Shanshan Qin Tingting Qiao Wen Jiang Junyu Tong Ganghua Lu Dingwei Gao Mengyu Zhang Zhongwei Lv Dan Li Li Chai Source Type: research
Autoimmune Implications in a Patient with Graves' Hyperthyroidism, Pre-eclampsia with Severe Features, and Primary Aldosteronism
Conclusions: This patient manifested severe GD with antibodies undetectable by conventional TSI and TSH receptor assays and accelerated hypertension from PA simultaneously. These conditions were successfully treated separately by spironolactone and thyroidectomy. Autoimmune PA was considered likely given the clinical picture. The diagnosis of PA should be considered in hypertension with GD.PMID:38256430 | PMC:PMC10820415 | DOI:10.3390/medicina60010170 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - January 23, 2024 Category: Universities & Medical Training Authors: Benjamin Lin Lauren Robinson Basem Soliman Jill Gulizia Stephen Usala Source Type: research
Drug-induced hypothyroidism in tuberculosis
Expert Rev Endocrinol Metab. 2024 Jan 19:1-8. doi: 10.1080/17446651.2024.2307525. Online ahead of print.ABSTRACTINTRODUCTION: Adverse reactions to tuberculosis treatment can impact patient adherence and prognosis. Hypothyroidism is a frequent adverse reaction caused using ethionamide, prothionamide, and para-aminosalicylic acid and is often underdiagnosed.AREAS COVERED: We searched Scielo, Scopus, and EMBASE databases, including 67 articles. Antitubercular drug-induced hypothyroidism has a prevalence of 17%. It occurs after 2 to 3 months of treatment and resolves within 4 to 6 weeks after discontinuation. It is postulated ...
Source: Expert Review of Endocrinology and Metabolism - January 23, 2024 Category: Endocrinology Authors: Juan Eduardo Quiroz-Aldave Mar ía Del Carmen Durand-Vásquez Elman Rolando Gamarra-Osorio Luis Alberto Concepci ón-Urteaga Samuel Pecho-Silva Luis Alejandro Rodr íguez-Hidalgo Marcio Jos é Concepción-Zavaleta Source Type: research
Are sonographic characteristics of Hashimoto ’s thyroiditis related with immunologic parameters? A cross-sectional study
ConclusionTOA, Ig G4 levels and severity of hypothyroidism were associated with ultrasonographic features such as parenchymal heterogeneity and fibrosis in Hashimoto ’s thyroiditis. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - January 21, 2024 Category: Endocrinology Source Type: research
Response to Xiang and Zhang re: "Active Surveillance Outcomes of Patients with Low-Risk Papillary Thyroid Microcarcinoma According to Levothyroxine Treatment Status"
Thyroid. 2024 Feb 13. doi: 10.1089/thy.2023.0697. Online ahead of print.NO ABSTRACTPMID:38226613 | DOI:10.1089/thy.2023.0697 (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - January 16, 2024 Category: Endocrinology Authors: Akira Miyauchi Source Type: research
