The effect of low-level laser therapy on the oxidative stress level and quality of life in patients with Hashimoto's thyroiditis
This study aimed to examine the effects of low-level laser therapy (LLLT) combined with levothyroxine replacement therapy on thyroid function, oxidative stress (OS), and quality of life in patients with Hashimoto's thyroiditis (HT). Forty-six patients diagnosed with HT were randomized to receive active LLLT (n = 23) and sham LLLT (n = 23) twice a week for three weeks. Clinical and laboratory evaluations of the participants were performed before treatment and three months after treatment. Biochemical parameters were taken from the patient file requested by the physician as a routine examination. Malondialdehyde and nitricox...
Source: Free Radical Research - April 17, 2024 Category: Research Authors: S ümeyye Tunç Şükriye Leyla Altuntaş Murat Atmaca Çağrı Çakıcı T ürkan Yiğitbaşı Yeong-Cheng Liou Wei-An Chang Source Type: research
Evaluation of the therapeutic efficacy of different doses of LT4 in pregnant women with high-normal TSH levels and TPOAb positivity in the first half of pregnancy
The objective was to investigate the efficacy of different doses of levothyroxine therapy among pregnant women exhibiting high-normal thyroid stimulating hormone levels and positive thyroid peroxidase antibodi... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 10, 2024 Category: Lipidology Authors: Xin Tian, Yajuan Xu, Yanjie Ban, Jingjing Li, Lin Hu, Dong Liu, Lulu Hu, Zongzong Sun, Miao Zhang, Chenchen Zhang, Yixin Wang and Pengkun Lin Tags: Research Source Type: research
Effects of Levothyroxine Treatment on Fertility and Pregnancy Outcomes in Subclinical Hypothyroidism: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Thyroid ®,Volume 34, Issue 4, Page 519-530, April 2024. (Source: Thyroid)
Source: Thyroid - April 4, 2024 Category: Endocrinology Authors: Akiko Sankoda Hitomi Suzuki Misa Imaizumi Ai Yoshihara Sakiko Kobayashi Miyuki Katai Katsuhiko Hamada Yoh Hidaka Aya Yoshihara Hannah Nakamura Sumihisa Kubota Maiko Kakita-Kobayashi Akira Iwase Takashi Sugiyama Erika Ota Naoko Arata Source Type: research
Levothyroxine-sodium
(Source: Reactions Weekly)
Source: Reactions Weekly - April 1, 2024 Category: Drugs & Pharmacology Source Type: research
Increased risk of diabetes mellitus and hyperlipidemia in patients with differentiated thyroid cancer
CONCLUSIONS: Patients with DTC had an increased risk of CMD, especially DM and hyperlipidemia, but a low risk of CMD mortality. Special attention to metabolic diseases is required in the long-term follow-up of patients with DTC.PMID:38536878 | DOI:10.1093/ejendo/lvae026 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - March 27, 2024 Category: Endocrinology Authors: Hwa Young Ahn Jooyoung Lee Jinmo Kang Eun Kyung Lee Source Type: research
Increased risk of diabetes mellitus and hyperlipidemia in patients with differentiated thyroid cancer
CONCLUSIONS: Patients with DTC had an increased risk of CMD, especially DM and hyperlipidemia, but a low risk of CMD mortality. Special attention to metabolic diseases is required in the long-term follow-up of patients with DTC.PMID:38536878 | DOI:10.1093/ejendo/lvae026 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - March 27, 2024 Category: Endocrinology Authors: Hwa Young Ahn Jooyoung Lee Jinmo Kang Eun Kyung Lee Source Type: research
Association of pharmacogenomic, clinical and behavioural factors with oral levothyroxine (LT-4) dose of hypothyroid patients in Sri Lanka: a matched case control study
Hypothyroidism is a common endocrine disorder that exerts a substantial influence on people all over the world. Levothyroxine (LT-4) is the drug of choice for the treatment of hypothyroidism and the starting o... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - March 27, 2024 Category: Genetics & Stem Cells Authors: S. S. Dalugodage, Gayan Bowatte, Charles Antonypillai, S. Rajapakse and T. M. I. U. K. Tennakoon Tags: Study Protocol Source Type: research
Potential risks and benefits of desiccated thyroid extract for the treatment of hypothyroidism: A systematic review
CONCLUSIONS: Most studies of DTE treatment are hampered by an inferior design, and data on long-term effects and side effects are lacking. Two RCTs could not demonstrate any difference in QoL or symptom scores when comparing DTE with other thyroid hormone substitutions. Future trials of DTE in patients with hypothyroidism should be based on adequate study designs, validated measures of QoL, patients with reduced QoL, and the assessment of biomarkers reflecting long-term adverse effects.PMID:38526391 | DOI:10.1089/thy.2023.0649 (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - March 25, 2024 Category: Endocrinology Authors: Kamilla Ryom Riis Camilla B øgelund Larsen Steen Joop Bonnema Source Type: research
Thyroid hormone homeostasis in levothyroxine-treated patients: Findings from ELSA-Brasil
CONCLUSION: The present results challenge the dogma that treatment with LT4 for hypothyroidism restores TH homeostasis in all patients. A substantial number of LT4-treated patients exhibit repeated FT4 and FT3 levels outside the normal reference range, despite normal TSH levels. Further studies are needed to define the clinical implications of these findings.PMID:38506164 | DOI:10.1210/clinem/dgae139 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - March 20, 2024 Category: Endocrinology Authors: Gustavo C Penna Isabela M Bensenor Antonio C Bianco Matthew D Ettleson Source Type: research
