European Society of Endocrinology and Endocrine Society Joint Clinical Guideline: Diagnosis and therapy of glucocorticoid-induced adrenal insufficiency
Eur J Endocrinol. 2024 May 2;190(5):G25-G51. doi: 10.1093/ejendo/lvae029.ABSTRACTGlucocorticoids are widely prescribed as anti-inflammatory and immunosuppressive agents. This results in at least 1% of the population using chronic glucocorticoid therapy, being at risk for glucocorticoid-induced adrenal insufficiency. This risk is dependent on the dose, duration and potency of the glucocorticoid, route of administration, and individual susceptibility. Once glucocorticoid-induced adrenal insufficiency develops or is suspected, it necessitates careful education and management of affected patients. Tapering glucocorticoids can ...
Source: European Journal of Endocrinology - May 7, 2024 Category: Endocrinology Authors: Felix Beuschlein Tobias Else Irina Bancos Stefanie Hahner Oksana Hamidi Leonie van Hulsteijn Eystein S Husebye Niki Karavitaki Alessandro Prete Anand Vaidya Christine Yedinak Olaf M Dekkers Source Type: research
Integrative Clinical, Hormonal and Molecular Data associate with Invasiveness in Acromegaly: REMAH Study
CONCLUSIONS: A specific combination of clinical/analytical/molecular variables was found to be associated with tumor invasiveness and growth capacity in GHomas. Pre-treatment with first-line drugs for acromegaly did not significantly modify the expression of the most relevant biomarkers in our association model. These findings provide valuable insights for risk stratification and personalized management of GHomas.PMID:38701338 | DOI:10.1093/ejendo/lvae045 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - May 3, 2024 Category: Endocrinology Authors: Miguel Sampedro-Nu ñez Aura Dulcinea Herrera-Mart ínez Alejandro Ib áñez-Costa Esther Rivero-Cort és Eva Venegas Mercedes Robledo Rebeca Mart ínez-Hernández Araceli Garc ía-Martínez Joan Gil Mireia Jord à Judith L ópez-Fernández Inmaculada Gav Source Type: research
Integrative Clinical, Hormonal and Molecular Data associate with Invasiveness in Acromegaly: REMAH Study
CONCLUSIONS: A specific combination of clinical/analytical/molecular variables was found to be associated with tumor invasiveness and growth capacity in GHomas. Pre-treatment with first-line drugs for acromegaly did not significantly modify the expression of the most relevant biomarkers in our association model. These findings provide valuable insights for risk stratification and personalized management of GHomas.PMID:38701338 | DOI:10.1093/ejendo/lvae045 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - May 3, 2024 Category: Endocrinology Authors: Miguel Sampedro-Nu ñez Aura Dulcinea Herrera-Mart ínez Alejandro Ib áñez-Costa Esther Rivero-Cort és Eva Venegas Mercedes Robledo Rebeca Mart ínez-Hernández Araceli Garc ía-Martínez Joan Gil Mireia Jord à Judith L ópez-Fernández Inmaculada Gav Source Type: research
Integrative Clinical, Hormonal and Molecular Data associate with Invasiveness in Acromegaly: REMAH Study
CONCLUSIONS: A specific combination of clinical/analytical/molecular variables was found to be associated with tumor invasiveness and growth capacity in GHomas. Pre-treatment with first-line drugs for acromegaly did not significantly modify the expression of the most relevant biomarkers in our association model. These findings provide valuable insights for risk stratification and personalized management of GHomas.PMID:38701338 | DOI:10.1093/ejendo/lvae045 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - May 3, 2024 Category: Endocrinology Authors: Miguel Sampedro-Nu ñez Aura Dulcinea Herrera-Mart ínez Alejandro Ib áñez-Costa Esther Rivero-Cort és Eva Venegas Mercedes Robledo Rebeca Mart ínez-Hernández Araceli Garc ía-Martínez Joan Gil Mireia Jord à Judith L ópez-Fernández Inmaculada Gav Source Type: research
Integrative Clinical, Hormonal and Molecular Data associate with Invasiveness in Acromegaly: REMAH Study
CONCLUSIONS: A specific combination of clinical/analytical/molecular variables was found to be associated with tumor invasiveness and growth capacity in GHomas. Pre-treatment with first-line drugs for acromegaly did not significantly modify the expression of the most relevant biomarkers in our association model. These findings provide valuable insights for risk stratification and personalized management of GHomas.PMID:38701338 | DOI:10.1093/ejendo/lvae045 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - May 3, 2024 Category: Endocrinology Authors: Miguel Sampedro-Nu ñez Aura Dulcinea Herrera-Mart ínez Alejandro Ib áñez-Costa Esther Rivero-Cort és Eva Venegas Mercedes Robledo Rebeca Mart ínez-Hernández Araceli Garc ía-Martínez Joan Gil Mireia Jord à Judith L ópez-Fernández Inmaculada Gav Source Type: research
Long term pituitary function, functional- and patient reported outcomes in severe acquired brain injury
CONCLUSION: Patients with severe acquired brain injury may develop long-term hypothalamus-pituitary insufficiency, with an equal occurrence in TBI and NTBI patients. In both cases, mainly isolated deficiencies, most commonly affecting the gonadal axis were seen. Insufficiencies were unrelated to functional outcomes and patient-reported outcomes probably reflecting the complexity and heterogeneous manifestations in both patient groups.PMID:38679947 | DOI:10.1093/ejendo/lvae047 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - April 29, 2024 Category: Endocrinology Authors: Djordje Marina Ulla Feldt-Rasmussen Marianne Klose Source Type: research
Prevalence and predictive features of metabolic dysfunction-associated steatotic liver disease in type 1 diabetes
CONCLUSION: Individuals with type 1 diabetes and high blood pressure, older age, BMI and duration of disease could be considered at high-risk for developing MASLD.PMID:38679966 | DOI:10.1093/ejendo/lvae043 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - April 29, 2024 Category: Endocrinology Authors: Coco M Fuhri Snethlage Abraham S Meijnikman Anne Linde Mak Elena Rampanelli Bas Voermans Cengiz A K Callender Pleun de Groen Bart O Roep Dani ël H van Raalte Filip K Knop Adriaan G Holleboom Max Nieuwdorp Nordin M J Hanssen Source Type: research
Long term pituitary function, functional- and patient reported outcomes in severe acquired brain injury
CONCLUSION: Patients with severe acquired brain injury may develop long-term hypothalamus-pituitary insufficiency, with an equal occurrence in TBI and NTBI patients. In both cases, mainly isolated deficiencies, most commonly affecting the gonadal axis were seen. Insufficiencies were unrelated to functional outcomes and patient-reported outcomes probably reflecting the complexity and heterogeneous manifestations in both patient groups.PMID:38679947 | DOI:10.1093/ejendo/lvae047 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - April 29, 2024 Category: Endocrinology Authors: Djordje Marina Ulla Feldt-Rasmussen Marianne Klose Source Type: research
Prevalence and predictive features of metabolic dysfunction-associated steatotic liver disease in type 1 diabetes
CONCLUSION: Individuals with type 1 diabetes and high blood pressure, older age, BMI and duration of disease could be considered at high-risk for developing MASLD.PMID:38679966 | DOI:10.1093/ejendo/lvae043 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - April 29, 2024 Category: Endocrinology Authors: Coco M Fuhri Snethlage Abraham S Meijnikman Anne Linde Mak Elena Rampanelli Bas Voermans Cengiz A K Callender Pleun de Groen Bart O Roep Dani ël H van Raalte Filip K Knop Adriaan G Holleboom Max Nieuwdorp Nordin M J Hanssen Source Type: research
Long term pituitary function, functional- and patient reported outcomes in severe acquired brain injury
CONCLUSION: Patients with severe acquired brain injury may develop long-term hypothalamus-pituitary insufficiency, with an equal occurrence in TBI and NTBI patients. In both cases, mainly isolated deficiencies, most commonly affecting the gonadal axis were seen. Insufficiencies were unrelated to functional outcomes and patient-reported outcomes probably reflecting the complexity and heterogeneous manifestations in both patient groups.PMID:38679947 | DOI:10.1093/ejendo/lvae047 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - April 29, 2024 Category: Endocrinology Authors: Djordje Marina Ulla Feldt-Rasmussen Marianne Klose Source Type: research
Prevalence and predictive features of metabolic dysfunction-associated steatotic liver disease in type 1 diabetes
CONCLUSION: Individuals with type 1 diabetes and high blood pressure, older age, BMI and duration of disease could be considered at high-risk for developing MASLD.PMID:38679966 | DOI:10.1093/ejendo/lvae043 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - April 29, 2024 Category: Endocrinology Authors: Coco M Fuhri Snethlage Abraham S Meijnikman Anne Linde Mak Elena Rampanelli Bas Voermans Cengiz A K Callender Pleun de Groen Bart O Roep Dani ël H van Raalte Filip K Knop Adriaan G Holleboom Max Nieuwdorp Nordin M J Hanssen Source Type: research
Long term pituitary function, functional- and patient reported outcomes in severe acquired brain injury
CONCLUSION: Patients with severe acquired brain injury may develop long-term hypothalamus-pituitary insufficiency, with an equal occurrence in TBI and NTBI patients. In both cases, mainly isolated deficiencies, most commonly affecting the gonadal axis were seen. Insufficiencies were unrelated to functional outcomes and patient-reported outcomes probably reflecting the complexity and heterogeneous manifestations in both patient groups.PMID:38679947 | DOI:10.1093/ejendo/lvae047 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - April 29, 2024 Category: Endocrinology Authors: Djordje Marina Ulla Feldt-Rasmussen Marianne Klose Source Type: research
Prevalence and predictive features of metabolic dysfunction-associated steatotic liver disease in type 1 diabetes
CONCLUSION: Individuals with type 1 diabetes and high blood pressure, older age, BMI and duration of disease could be considered at high-risk for developing MASLD.PMID:38679966 | DOI:10.1093/ejendo/lvae043 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - April 29, 2024 Category: Endocrinology Authors: Coco M Fuhri Snethlage Abraham S Meijnikman Anne Linde Mak Elena Rampanelli Bas Voermans Cengiz A K Callender Pleun de Groen Bart O Roep Dani ël H van Raalte Filip K Knop Adriaan G Holleboom Max Nieuwdorp Nordin M J Hanssen Source Type: research
Glucose pattern in children with classical congenital adrenal hyperplasia: evidence from continuous glucose monitoring
Eur J Endocrinol. 2024 Apr 26:lvae042. doi: 10.1093/ejendo/lvae042. Online ahead of print.NO ABSTRACTPMID:38668689 | DOI:10.1093/ejendo/lvae042 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - April 26, 2024 Category: Endocrinology Authors: A Galderisi D Kariyawasam A Stoupa A Quoc G Pinto M Viaud S Brabant J Beltrand M Polak D Samara-Boustani Source Type: research
Glucose pattern in children with classical congenital adrenal hyperplasia: evidence from continuous glucose monitoring
Eur J Endocrinol. 2024 Apr 26:lvae042. doi: 10.1093/ejendo/lvae042. Online ahead of print.NO ABSTRACTPMID:38668689 | DOI:10.1093/ejendo/lvae042 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - April 26, 2024 Category: Endocrinology Authors: A Galderisi D Kariyawasam A Stoupa A Quoc G Pinto M Viaud S Brabant J Beltrand M Polak D Samara-Boustani Source Type: research
