Thyroid hormones mediate the impact of early-life stress on ventral tegmental area gene expression and behavior
Horm Behav. 2023 Dec 22;159:105472. doi: 10.1016/j.yhbeh.2023.105472. Online ahead of print.ABSTRACTProper thyroid function is essential to the developing brain, including dopamine neuron differentiation, growth, and maintenance. Stress across the lifespan impacts thyroid hormone signaling and anxiety disorders and depression have been associated with thyroid dysfunction (both hypo- and hyper-active). However, less is known about how stress during postnatal development impacts thyroid function and related brain development. Our previous work in mice demonstrated that early-life stress (ELS) transiently impinged on expressi...
Source: Hormones and Behavior - December 23, 2023 Category: Endocrinology Authors: Shannon N Bennett Austin B Chang Forrest D Rogers Parker Jones Catherine Jensen Pe ña Source Type: research
Thyroid hormones mediate the impact of early-life stress on ventral tegmental area gene expression and behavior
Horm Behav. 2023 Dec 22;159:105472. doi: 10.1016/j.yhbeh.2023.105472. Online ahead of print.ABSTRACTProper thyroid function is essential to the developing brain, including dopamine neuron differentiation, growth, and maintenance. Stress across the lifespan impacts thyroid hormone signaling and anxiety disorders and depression have been associated with thyroid dysfunction (both hypo- and hyper-active). However, less is known about how stress during postnatal development impacts thyroid function and related brain development. Our previous work in mice demonstrated that early-life stress (ELS) transiently impinged on expressi...
Source: Hormones and Behavior - December 23, 2023 Category: Endocrinology Authors: Shannon N Bennett Austin B Chang Forrest D Rogers Parker Jones Catherine Jensen Pe ña Source Type: research
Quadruple overlapping autoimmune diseases manifested as sarcoidosis with mediastinal lymphadenopathy: a case report
We present a rare case of a 55-year-old female patient with quadruple overlapping autoimmune diseases, including vitiligo, autoimmune hypothyroidism, ulcerative colitis, and sarcoidosis with mediastinal lymphadenopathy. The patient had been suffering from vitiligo since 2003 and was diagnosed with autoimmune hypothyroidism and ulcerative colitis through thyroid ultrasound and colonoscopy, respectively. After physical examination, mediastinal lymph nodes enlargement was detected, and sarcoidosis was diagnosed through ultrasound bronchoscope-guided transbronchial needle aspiration (EBUS-TBNA), which is a quadruple overlappin...
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - December 21, 2023 Category: Respiratory Medicine Authors: Mengjie Li Huan Wang Cuiping Li Linming Su Jian Zhu Source Type: research
Randomized Double-blind Placebo-controlled Trial on Levothyroxine and Liothyronine Combination Therapy in Totally Thyroidectomized Subjects: the Levolio Study
CONCLUSIONS: Six months of combination therapy with twice daily LT3 dose adapted according to TSH-level do not significantly change peripheral tissue response or quality of life, despite an increase in the fT3/fT4 ratio.PMID:38124252 | DOI:10.1093/ejendo/lvad172 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - December 21, 2023 Category: Endocrinology Authors: Brigante Giulia Santi Daniele Boselli Gisella Margiotta Gianluca Corleto Rossella Monzani Maria Laura Craparo Andrea Locaso Michela Sperduti Samantha Roy Neena Casarini Livio Trenti Tommaso Tagliavini Simonetta De Santis Maria Cristina Roli Laura Rochira Source Type: research
Quadruple overlapping autoimmune diseases manifested as sarcoidosis with mediastinal lymphadenopathy: a case report
We present a rare case of a 55-year-old female patient with quadruple overlapping autoimmune diseases, including vitiligo, autoimmune hypothyroidism, ulcerative colitis, and sarcoidosis with mediastinal lymphadenopathy. The patient had been suffering from vitiligo since 2003 and was diagnosed with autoimmune hypothyroidism and ulcerative colitis through thyroid ultrasound and colonoscopy, respectively. After physical examination, mediastinal lymph nodes enlargement was detected, and sarcoidosis was diagnosed through ultrasound bronchoscope-guided transbronchial needle aspiration (EBUS-TBNA), which is a quadruple overlappin...
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - December 21, 2023 Category: Respiratory Medicine Authors: Mengjie Li Huan Wang Cuiping Li Linming Su Jian Zhu Source Type: research
Randomized Double-blind Placebo-controlled Trial on Levothyroxine and Liothyronine Combination Therapy in Totally Thyroidectomized Subjects: the Levolio Study
CONCLUSIONS: Six months of combination therapy with twice daily LT3 dose adapted according to TSH-level do not significantly change peripheral tissue response or quality of life, despite an increase in the fT3/fT4 ratio.PMID:38124252 | DOI:10.1093/ejendo/lvad172 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - December 21, 2023 Category: Endocrinology Authors: Brigante Giulia Santi Daniele Boselli Gisella Margiotta Gianluca Corleto Rossella Monzani Maria Laura Craparo Andrea Locaso Michela Sperduti Samantha Roy Neena Casarini Livio Trenti Tommaso Tagliavini Simonetta De Santis Maria Cristina Roli Laura Rochira Source Type: research
Quadruple overlapping autoimmune diseases manifested as sarcoidosis with mediastinal lymphadenopathy: a case report
We present a rare case of a 55-year-old female patient with quadruple overlapping autoimmune diseases, including vitiligo, autoimmune hypothyroidism, ulcerative colitis, and sarcoidosis with mediastinal lymphadenopathy. The patient had been suffering from vitiligo since 2003 and was diagnosed with autoimmune hypothyroidism and ulcerative colitis through thyroid ultrasound and colonoscopy, respectively. After physical examination, mediastinal lymph nodes enlargement was detected, and sarcoidosis was diagnosed through ultrasound bronchoscope-guided transbronchial needle aspiration (EBUS-TBNA), which is a quadruple overlappin...
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - December 21, 2023 Category: Respiratory Medicine Authors: Mengjie Li Huan Wang Cuiping Li Linming Su Jian Zhu Source Type: research
