Novel treatments for progressive multifocal leukoencephalopathy.
This article reviews research into novel therapies: immune checkpoint-blocking antibodies (nivolumab and pembrolizumab), allogenic BK virus-specific T cell treatment and filgrastim. Results for these therapies in small clinical trials are promising, but further research is required to assess efficacy fully. PMID: 32730143 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Bennett KM, Fernandes PM Tags: Br J Hosp Med (Lond) Source Type: research

The impact of the COVID-19 pandemic on medical education.
Abstract The coronavirus pandemic has caused major disruption of systems worldwide, including education and health services. The duration and scale of the impact is yet to be established. The effect of the pandemic on medical education should be managed on the basis of early response, alternative education options and future changes and actions. PMID: 32730144 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Samaraee AA Tags: Br J Hosp Med (Lond) Source Type: research

Making workplace wellbeing a priority for the NHS.
This article outlines strategies to improve the NHS as a place of work. PMID: 32730145 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Miah R, Ahmed N Tags: Br J Hosp Med (Lond) Source Type: research

Developmental dysplasia of the hip.
Abstract Developmental dysplasia of the hip encompasses a range of hip abnormalities in which the femoral head and acetabulum fail to develop and articulate anatomically. Developmental dysplasia of the hip is a clinically important condition, with a prevalence of 1-2/1000 in unscreened populations and 5-30/1000 in clinically screened populations. The pathology is incongruence between the femoral head and the acetabulum, which can be caused by an abnormally shaped femoral head, acetabulum, or both. This results in a spectrum of different hip abnormalities. The precise aetiology behind developmental dysplasia of the...
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Zhang S, Doudoulakis KJ, Khurwal A, Sarraf KM Tags: Br J Hosp Med (Lond) Source Type: research

Persistent opacity on chest X-ray: take a closer look at the ribs.
PMID: 32730147 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Cheng ZR, Thomas B, Pugalenthi A, Tan YH, Teoh OH Tags: Br J Hosp Med (Lond) Source Type: research

Eye care in the intensive care unit: intraocular pressure in prone patients with COVID-19.
PMID: 32730148 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Deol S, Hanna-Jumma S, Tsaousis KT Tags: Br J Hosp Med (Lond) Source Type: research

COVID-19 and international medical graduates: the frustrated and forgotten future NHS workforce.
PMID: 32730149 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Kumaran NK, Mahesh A, Sankar TK, Moorthy A Tags: Br J Hosp Med (Lond) Source Type: research

An unusual case of biventricular thrombi.
PMID: 32730150 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Wang T, Xu Y, Lin J, Zhou B, Zhang Q Tags: Br J Hosp Med (Lond) Source Type: research

Time-critical administration of corticosteroid rescue therapy for COVID-19 pneumonitis in a ward-based patient with chronic obstructive pulmonary disease.
PMID: 32730151 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Kuzeva A, Dost S, Lams B, Agarwal S, Furmedge DS Tags: Br J Hosp Med (Lond) Source Type: research

Alogliptin-induced bullous pemphigoid.
PMID: 32730152 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Zafar M, Shahbaz M, Hawley I, Rahmani MJ Tags: Br J Hosp Med (Lond) Source Type: research

Oesophago-atrial fistula secondary to ingestion of battery acid.
PMID: 32730153 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Mullhi RK, Veenith T Tags: Br J Hosp Med (Lond) Source Type: research

An insidious coronary arterial pathology diagnosed with an adenosine stress computed tomography perfusion study.
PMID: 32730154 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Aribal S Tags: Br J Hosp Med (Lond) Source Type: research

Autoantibodies in the diagnostic work-up of neuropathy: clinically useful or purely academic?
This article reviews the main immunological tests used to search for specific autoantibodies in the setting of neuropathy and discusses their potential diagnostic importance, together with the eventual therapeutic implications of results obtained. PMID: 32730155 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Sahi N, Ghasemi M, Rajabally YA Tags: Br J Hosp Med (Lond) Source Type: research

Simulation of realistic nephrology case scenarios to facilitate intra-professional team learning.
This article describes a simulation course designed to facilitate team learning to improve the care of nephrology patients, and presents outcome data over 2 years. METHODS: A full-day course, using high fidelity manikins, was designed for nephrology specialty trainees and nurse specialists. Nineteen learners (eleven specialty trainees and eight nurse specialists) and nine multidisciplinary team faculty members attended. Evaluation used pre- and post-course assessments, with a 1-year follow-up questionnaire. RESULTS: Following the course, improved knowledge scores, 56% to 72% (P
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Watson K, Gosling N, Broom C, Snelgrove H, Popoola J Tags: Br J Hosp Med (Lond) Source Type: research

James Syme: distinguished Edinburgh surgeon of the 19th century.
Abstract This year marks the 150th anniversary of the death of James Syme, one of the most distinguished members of the Edinburgh school of surgery in the 19th century. PMID: 32730157 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Ellis H Tags: Br J Hosp Med (Lond) Source Type: research

The BOAST recommendations for care of the older or frail orthopaedic trauma patient.
This article expands upon the British Orthopaedic Association Standards for Trauma and Orthopaedics guidelines for the management of the older or frail orthopaedic trauma patient. Optimisation of the patient is key to a successful surgical outcome, because these patients often have significant comorbidities involving bone health, nutrition, cognitive function and cardiovascular stability. This article discusses the evidence base for tailoring the management of these patients and the importance of doing so in an ageing population. It considers the requisite preoperative procedures and investigations, guidelines for specific...
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Sacks B, Mughal HN, Ahluwalia A, Rudran B, Parmar KR Tags: Br J Hosp Med (Lond) Source Type: research

Multiple spontaneous coronary thrombosis causing ST-elevation myocardial infarction in a patient with COVID-19.
PMID: 32730159 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Kurdi H, Obaid DR, UlHaq Z, Ionescu A, Sekar B Tags: Br J Hosp Med (Lond) Source Type: research

Extent of infectious SARS-CoV-2 aerosolisation as a result of oesophagogastroduodenoscopy or colonoscopy.
CONCLUSIONS: As it is a highly infectious disease, clinicians treating patients with COVID-19 require effective personal protective equipment. The main routes of infection are direct contact and droplets in the air and on surfaces. Aerosolisation carries a substantial risk of infection, so any aerosol-producing procedure, such as endoscopy, should be performed wearing personal protective equipment and with extra caution to protect the endoscopist, staff and patients from cross-infection via the respiratory system. PMID: 32730160 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Hussain A, Singhal T, El-Hasani S Tags: Br J Hosp Med (Lond) Source Type: research

Clavicle fractures.
This article provides an overview of the presentation, assessment and management of clavicle fractures for both core surgical trainees and acute care common stem/emergency medicine trainees. PMID: 32730161 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Morgan C, Bennett-Brown K, Stebbings A, Li L, Dattani R Tags: Br J Hosp Med (Lond) Source Type: research

Virtual consent for virtual patients: benefits of implementation in a peri- and post-COVID-19 era.
Abstract The COVID-19 pandemic has caused major disruptions to the healthcare system, including increased reliance on virtual services, particularly clinic appointments. This leads to difficulty in obtaining informed consent; the vast majority of patients now need to be consented on the day of the procedure. To reduce problems with this process, the practice of obtaining electronic consent may be the correct way forward. PMID: 32730162 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Mukherjee S, Raza A Tags: Br J Hosp Med (Lond) Source Type: research

The chopstick: a rare and serious cause of penetrating oropharyngeal trauma in a 6-year-old.
PMID: 32730163 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Song N, Liu F, Liu Y Tags: Br J Hosp Med (Lond) Source Type: research

Management of limb length problems during total hip arthroplasty for patients with developmental dysplasia of the hip.
Abstract The anatomy of the acetabulum and femur is usually significantly altered in people with developmental dysplasia of the hip and this leads to secondary osteoarthritis of the hip joint. Ideal positioning of implants and reduction of the joint is technically demanding during arthroplasty. Lengthening may result in nerve palsies and therefore procedures may have to be undertaken to shorten the femur. Other complications include dislocation and non-union at the shortening osteotomy site. Thorough preoperative planning and templating is required before surgery to assess the need for shortening. Shortening osteo...
Source: British Journal of Hospital Medicine - July 2, 2020 Category: Internal Medicine Authors: Benjamin B, Haddad FS Tags: Br J Hosp Med (Lond) Source Type: research

Everything you need to know about deprivation of liberty safeguards.
This article outlines how deprivation of liberty safeguards work, how a deprivation of liberty safeguards is applied for and obtained, what to discuss with the next of kin, and some special circumstances to consider. It also provides information about the criteria by which deprivation of liberty safeguards applications are assessed and the process by which this is done. This provides an overview for junior doctors working in secondary care, to increase their knowledge and confidence when patients require a deprivation of liberty safeguards application. PMID: 32589526 [PubMed - as supplied by publisher] (Source: Britis...
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Callaghan H, Illsley A Tags: Br J Hosp Med (Lond) Source Type: research

SPACES implementation sticker.
PMID: 32589527 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Whittaker E Tags: Br J Hosp Med (Lond) Source Type: research

Acute oesophageal necrosis or 'black oesophagus'.
PMID: 32589528 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Angelov T, Churchev S, Kolev N, Vladimirov B, Golemanov B Tags: Br J Hosp Med (Lond) Source Type: research

Sugammadex: routine use vs restrictive use.
This article reflects on how more liberal use of sugammadex might alter patient experience, anaesthetic delivery and surgical techniques. PMID: 32589529 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Ashiru G, Carrington M Tags: Br J Hosp Med (Lond) Source Type: research

Helping people to live well with chronic kidney disease.
Abstract Reduced glomerular filtration rate and presence of albuminuria are both associated with increased risk of several poor outcomes. People with chronic kidney disease also commonly suffer from lower quality of life than their age-matched peers. The experiences reported by patients with chronic kidney disease include being shocked by the diagnosis, being uncertain about the cause and worrying about progression and future treatment. Issues such as depression, pain and fatigue are common in people with chronic kidney disease. Helping people to live well with a long-term condition like chronic kidney disease sho...
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Fraser S, Taal M Tags: Br J Hosp Med (Lond) Source Type: research

Pulmonary embolism in acute medicine: a case-based review incorporating latest guidelines in the COVID-19 era.
This article presents four theoretical but realistic cases, each diagnosed with acute pulmonary embolism, but differing in levels of severity. These demonstrate how the guidelines can be applied in a clinical setting, with particular focus on risk stratification and management. PMID: 32589531 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Stevenson A, Davis S, Murch N Tags: Br J Hosp Med (Lond) Source Type: research

Anorexia nervosa in adolescents.
Abstract Anorexia nervosa is an eating disorder with peak onset in adolescence, which carries the highest mortality rate of all psychiatric illnesses. It is commonly comorbid with other physical and mental health problems, yet training on management of people with eating disorders and working knowledge of clinicians working with underweight adolescents is inconsistent. This review of anorexia nervosa in adolescents provides an overview of the presentation, aetiology and treatment of this disorder, with a particular focus on the assessment and management of physical health risks, including refeeding syndrome. ...
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Neale J, Hudson LD Tags: Br J Hosp Med (Lond) Source Type: research

Jules Bordet: immunologist, bacteriologist and Nobel Prize winner.
Abstract This year marks the 150th anniversary of the birth of Jules Jean Baptiste Vincent Bordet, to give him his full name, the Belgian immunologist and bacteriologist. PMID: 32589533 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Ellis H Tags: Br J Hosp Med (Lond) Source Type: research

Radiological manifestations of COVID-19: key points for the physician.
This article gives the hospital physician an overview of the radiological manifestations of COVID-19 disease, to improve knowledge and increase familiarity when reviewing radiographic images. PMID: 32589534 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Gravell RJ, Theodoreson MD, Buonsenso D, Curtis J Tags: Br J Hosp Med (Lond) Source Type: research

Cardiac herniation following pulmonary tuberculosis infection with sequential autopneumonectomy.
PMID: 32589535 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Chen KT, Wu FZ Tags: Br J Hosp Med (Lond) Source Type: research

Antiplatelet therapy for transient ischaemic attack and minor ischaemic stroke.
Abstract Transient ischaemic attacks carry an increased risk of large ischaemic stroke in the 90 days after an event. Patients need to be seen within 24 hours in a dedicated clinic to start secondary prevention. This editorial reviews evidence for consideration of early dual antiplatelet therapy after a transient ischaemic attack. PMID: 32589536 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Kalladka D, Rounis E Tags: Br J Hosp Med (Lond) Source Type: research

COVID-19 and rheumatology: is shielding really necessary?
Abstract Rheumatology patients who are taking immunosuppressants are considered to be at 'high risk' from COVID-19, hence have been self-isolating or shielding. However, they may be protected from the features of hyperinflammation driven by a 'cytokine storm', so may have better clinical outcomes if infected. This editorial discusses whether it may not be necessary to advise these patients to shield. PMID: 32589537 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Amani L, Warraich R, Patel N, Tahir H Tags: Br J Hosp Med (Lond) Source Type: research

Medical leadership in the NHS during the COVID-19 pandemic.
This article is based on the personal experiences of doctors in the NHS and insights into the frontline response to this situation. It reflects on leadership dilemmas and strategies implemented to overcome them, with a focus on systems thinking and adaptive leadership. PMID: 32589538 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Warraich S, Olabi B, Azhar B, Tanzeem SF, Fischer M Tags: Br J Hosp Med (Lond) Source Type: research

Should nasogastric tube insertion during the COVID-19 pandemic be considered as an aerosol-generating procedure?
Abstract Nasogastric tubes are used frequently in surgical patients for bowel decompression, provision of enteral nutritional support and preventing aspiration of gastric contents. There is no conclusive research into the risk of COVID-19 transmission associated with nasogastric tube insertion, although evidence from the severe acute respiratory syndrome outbreak appears to suggest that there is no increased risk of transmission. However, close contact with a COVID-19 patient, especially those displaying respiratory symptoms, is likely to increase the risk of transmission. Nasogastric tube insertion requires incre...
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Sturrock BR, Fanning SJ, Khan M, Sajid MS Tags: Br J Hosp Med (Lond) Source Type: research

Imaging in trauma of the facial skeleton and soft tissues of the neck.
This article gives a pictorial review of the imaging of craniofacial trauma, stratified according to the thirds of the face, followed by a review of blunt and penetrating trauma of the neck. It discusses appropriate imaging modalities for each trauma category, describes major patterns of craniofacial trauma on cross-sectional imaging and identifies clinically relevant imaging features that should trigger subspecialist review or be of relevance to pre-surgical planning. It starts with the upper third comprising frontal sinus fractures before describing the component fractures of the middle third (including nasal, zygomatico...
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Bitar G, Touska P Tags: Br J Hosp Med (Lond) Source Type: research

Eye care in the intensive care unit during the COVID-19 pandemic.
Abstract Ocular complications in critical care patients are common. There has been a surge in intensive care admissions following the COVID-19 outbreak. The management of COVID-19 exposes patients to a number of specific risk factors for developing ocular complications, which include non-invasive ventilation, mechanical ventilation and prone positioning. Consequently, it is likely that there will be an increase in the number of ocular complications secondary to the management of COVID-19 patients in the intensive care unit setting, and these complications could lead to permanent visual loss and blindness. Increase...
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Sansome SG, Lin PF Tags: Br J Hosp Med (Lond) Source Type: research

Aneurysm of cardiac muscular interventricular septum as a result of blunt chest trauma.
PMID: 32589542 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Arslan D, Keceli AM, Gokdemir M Tags: Br J Hosp Med (Lond) Source Type: research

Distal radius fractures: an evidence-based approach to assessment and management.
This article outlines the British Orthopaedic Association Standards for Trauma and Orthopaedics for the management of distal radius fractures. PMID: 32589543 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Vaghela KR, Velazquez-Pimentel D, Ahluwalia AK, Choraria A, Hunter A Tags: Br J Hosp Med (Lond) Source Type: research

A novel Caldicott-compliant hospital imaging protocol for open fracture photography.
Abstract Open fractures incur significant morbidity and mortality, and as such have standardised guidelines for their management. Photography of open fractures is an essential component of documentation in the treatment of open fractures as per the British Orthopaedic Association Standards of Trauma and National Institute for Health and Care Excellence guidelines. Smartphones have made photography easily accessible to the clinician, but serious concerns exist regarding data security and the consent process around the use of sensitive clinical images. This project sought to overcome this issue by developing a Caldi...
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Houston J, Ashby L, Ogidi J, Lui DF, Trompeter AJ Tags: Br J Hosp Med (Lond) Source Type: research

Postoperative nausea and vomiting.
Abstract Nausea and vomiting after surgery is common and can be both unpleasant and lead to an array of other adverse patient effects. Identification of high-risk patients and targeted prophylaxis can reduce its incidence and associated complications. PMID: 32589545 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Barnes J Tags: Br J Hosp Med (Lond) Source Type: research

Immunosuppression drug advice and COVID-19: are we doing more harm than good?
Abstract The National Institute for Health and Care Excellence guidelines advise stopping immunosuppressive drugs for confirmed or suspected COVID-19 patients with autoimmune and inflammatory disorders. This may not be in the patient's best interest, given the potential long-term consequences of not managing chronic conditions, and immunosuppression may even be protective in those affected with COVID-19. PMID: 32589546 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Warraich R, Amani L, Mediwake R, Tahir H Tags: Br J Hosp Med (Lond) Source Type: research

Different manifestations of COVID-19 pneumonia in a child: focal crazy paving sign on chest and three-dimensional computed tomography.
PMID: 32589547 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Aslan S, Cakir İM, Bekci T Tags: Br J Hosp Med (Lond) Source Type: research

A rare giant paediatric aneurysmal bone cyst in the paranasal sinus.
PMID: 32589548 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Song NY, Liu Y, Liu F Tags: Br J Hosp Med (Lond) Source Type: research

Pyoderma gangrenosum of the tongue.
PMID: 32589549 [PubMed - as supplied by publisher] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - June 2, 2020 Category: Internal Medicine Authors: Shakir J, Escudier M, Sanderson J, Hullah E, Carey B Tags: Br J Hosp Med (Lond) Source Type: research

Antiemetics: types, actions and uses.
Abstract Nausea and vomiting are common symptoms in the hospital setting, with numerous causes. Common precipitants leading to or complicating inpatient hospital admissions include nausea and vomiting secondary to drugs, gastrointestinal disturbances, metabolic aberrancies, and vestibular pathologies. Appropriate selection and prescribing of antiemetic drugs is therefore important for healthcare professionals. There are numerous antiemetics available to physicians, ranging from muscarinic, dopaminergic and serotoninergic drugs, each acting on a different part of the nausea-vomiting cascade. This review describes t...
Source: British Journal of Hospital Medicine - May 2, 2020 Category: Internal Medicine Authors: Dulay MS, Dulay JS Tags: Br J Hosp Med (Lond) Source Type: research

Assessing wrist pain: a simple guide.
This article looks at the bony and neurovascular anatomy of the wrist joint and describes a simple guide to clinical assessment of wrist pathology, highlighting the awareness of red flag signs, which would warrant an immediate referral for secondary care input. PMID: 32468936 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - May 2, 2020 Category: Internal Medicine Authors: Prasad G, Bhalli MJ Tags: Br J Hosp Med (Lond) Source Type: research

Antiphospholipid syndrome and challenges with direct oral anticoagulants.
This article reviews the diagnosis of thrombotic antiphospholipid syndrome, strategies for testing without interruption of anticoagulation, evidence concerning the safety of direct oral anticoagulants in this setting, and the implications for current investigation and management of unprovoked venous thromboembolism. PMID: 32468937 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - May 2, 2020 Category: Internal Medicine Authors: Booth S, Burton K, Hunt B, Desborough M Tags: Br J Hosp Med (Lond) Source Type: research

The impact of patients losing their sense of smell.
PMID: 32468938 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - May 2, 2020 Category: Internal Medicine Authors: Philpott C Tags: Br J Hosp Med (Lond) Source Type: research