Association between hip muscle strength/function and hip cartilage defects in sub-elite football players with hip/groin pain.
To explore associations between hip muscle strength and cartilage defects (presence and severity) on magnetic resonance imaging (MRI) in young adults with hip/groin pain participating in sub-elite football. (Source: Osteoarthritis and Cartilage)
Source: Osteoarthritis and Cartilage - April 20, 2024 Category: Rheumatology Authors: SL Coburn, KM Crossley, JL Kemp, F Gassert, J Luitjens, SJ Warden, AG Culvenor, MJ Scholes, MG King, P Lawrenson, T Link, JJ Heerey Source Type: research
Cancers, Vol. 16, Pages 1577: National Experiences from 30 Years of Provider-Mediated Cascade Testing in Lynch Syndrome Families & mdash;The Danish Model
In conclusion, the Danish model combining family- and provider-mediated contact can increase the effect of cascade genetic testing. (Source: Cancers)
Source: Cancers - April 20, 2024 Category: Cancer & Oncology Authors: Lars Joachim Lindberg Karin A. W. Wadt Christina Therkildsen Helle Vendel Petersen Tags: Article Source Type: research
The challenges of research data management in cardiovascular science: a DGK and DZHK position paper —executive summary
AbstractThe sharing and documentation of cardiovascular research data are essential for efficient use and reuse of data, thereby aiding scientific transparency, accelerating the progress of cardiovascular research and healthcare, and contributing to the reproducibility of research results. However, challenges remain. This position paper, written on behalf of and approved by the German Cardiac Society and German Centre for Cardiovascular Research, summarizes our current understanding of the challenges in cardiovascular research data management (RDM). These challenges include lack of time, awareness, incentives, and funding ...
Source: Clinical Research in Cardiology - April 19, 2024 Category: Cardiology Source Type: research
Evaluation of Moringa Oleifera Leaf Extract for its In vitro Antibacterial Properties, Mechanism of Action, and In vivo Corneal Ulcer Healing Effects in Rabbits' Eyes
Curr Drug Deliv. 2024 Apr 17. doi: 10.2174/0115672018275561240228065755. Online ahead of print.ABSTRACTM. oleifera is the most adapted tree species in different medicinal eco-systems and has resilience against climate changes. This multiple-use tree provides healthy foods, snacks, honey, and fuel. Besides this, it has immense promising applicationsby offering antimicrobial and antibacterial activities for targeted uses. This validates the court of Hippocrates that let food be the medicine and medicine be the food for which moringa qualifies. In view of this, the antioxidant and in vitro antibacterial potency of the hydro-e...
Source: Current Drug Delivery - April 19, 2024 Category: Drugs & Pharmacology Authors: Ayesha Bibi Meenakshi Dhanawat Shahbaz Aman Samrat Chauhan Rishabh Chalotra Somdutt Mujwar Narinder Kaur ChamasseHomary Maivagna Sumeet Gupta Source Type: research
The rebirth of epitope-based patent claims
CONCLUSIONS: Companies developing therapeutic antibodies or T cell receptors need to consider these developments in their strategic planning.PMID:38640147 | DOI:10.3233/HAB-240006 (Source: Human Antibodies)
Source: Human Antibodies - April 19, 2024 Category: Biochemistry Authors: Ulrich Storz Source Type: research
How Seeking Transfer Often Fails to Help Define Medically Inappropriate Treatment
Hastings Cent Rep. 2024 Mar;54(2):2. doi: 10.1002/hast.1572.ABSTRACTOn September 1, 2023, Texas made important revisions to it its decades-old statute granting legal safe harbor immunity to physicians who withhold or withdraw life-sustaining treatment over the objection of critically ill patients' surrogate decision-makers. However, lawmakers left untouched glaring flaws in a key safeguard for patients-the transfer option. The transfer option is ethically important because, when no hospital is willing to accept the patient in transfer, that fact is taken as strong evidence that the surrogates' treatment requests fall outsi...
Source: The Hastings Center Report - April 19, 2024 Category: Medical Ethics Authors: Douglas B White Thaddeus M Pope Source Type: research
Effect of Isocaloric, Time-Restricted Eating on Body Weight in Adults With Obesity : A Randomized Controlled Trial
CONCLUSION: In the setting of isocaloric eating, TRE did not decrease weight or improve glucose homeostasis relative to a UEP, suggesting that any effects of TRE on weight in prior studies may be due to reductions in caloric intake.PRIMARY FUNDING SOURCE: American Heart Association.PMID:38639542 | DOI:10.7326/M23-3132 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 19, 2024 Category: Internal Medicine Authors: Nisa M Maruthur Scott J Pilla Karen White Beiwen Wu May Thu Thu Maw Daisy Duan Ruth-Alma Turkson-Ocran Di Zhao Jeanne Charleston Courtney M Peterson Ryan J Dougherty Jennifer A Schrack Lawrence J Appel Eliseo Guallar Jeanne M Clark Source Type: research
Assessing Clinician Utilization of Next-Generation Antibiotics Against Resistant Gram-Negative Infections in U.S. Hospitals : A Retrospective Cohort Study
CONCLUSION: Despite FDA approval of 7 next-generation gram-negative antibiotics between 2014 and 2019, clinicians still frequently treat resistant gram-negative infections with older, generic antibiotics with suboptimal safety-efficacy profiles. Future antibiotics with innovative mechanisms targeting untapped pathogen niches, widely available susceptibility testing, and evidence demonstrating improved outcomes in resistant infections might enhance utilization.PRIMARY FUNDING SOURCE: U.S. Food and Drug Administration; NIH Intramural Research Program.PMID:38639548 | DOI:10.7326/M23-2309 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 19, 2024 Category: Internal Medicine Authors: Jeffrey R Strich Ahmed Mishuk Guoqing Diao Alexander Lawandi Willy Li Cumhur Y Demirkale Ahmed Babiker Alex Mancera Bruce J Swihart Morgan Walker Christina Yek Maniraj Neupane Nathaniel De Jonge Sarah Warner Sameer S Kadri National Institutes of Health An Source Type: research
Nationally standardized broad consent in practice: initial experiences, current developments, and critical assessment
DISCUSSION: The introduction of the MII consent documents at the university hospitals creates a uniform legal basis for the secondary use of patient data. However, the comprehensive implementation within the sites remains challenging. Therefore, minimum requirements for patient information and supplementary recommendations for best practice must be developed. The further development of the national legal framework for research will not render the participation and transparency mechanisms developed here obsolete.PMID:38639817 | DOI:10.1007/s00103-024-03878-6 (Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz)
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - April 19, 2024 Category: International Medicine & Public Health Authors: Sven Zenker Daniel Strech Roland Jahns Gabriele M üller Fabian Prasser Christoph Schickhardt Georg Schmidt Sebastian C Semler Eva Winkler Johannes Drepper Source Type: research
Mental health and wellbeing in mesothelioma: A qualitative study exploring what helps the wellbeing of those living with this illness and their informal carers
CONCLUSIONS: Findings have implications for nurses and other key professionals working in healthcare, community and legal settings supporting this client group, and for those living with mesothelioma who want to understand ways to enhance their own wellbeing.PMID:38640636 | DOI:10.1016/j.ejon.2024.102572 (Source: European Journal of Oncology Nursing)
Source: European Journal of Oncology Nursing - April 19, 2024 Category: Nursing Authors: Stephanie Ejegi-Memeh Virginia Sherborne Catriona Mayland Angela Tod Bethany H Taylor Source Type: research
Evaluation of Moringa Oleifera Leaf Extract for its In vitro Antibacterial Properties, Mechanism of Action, and In vivo Corneal Ulcer Healing Effects in Rabbits' Eyes
Curr Drug Deliv. 2024 Apr 17. doi: 10.2174/0115672018275561240228065755. Online ahead of print.ABSTRACTM. oleifera is the most adapted tree species in different medicinal eco-systems and has resilience against climate changes. This multiple-use tree provides healthy foods, snacks, honey, and fuel. Besides this, it has immense promising applicationsby offering antimicrobial and antibacterial activities for targeted uses. This validates the court of Hippocrates that let food be the medicine and medicine be the food for which moringa qualifies. In view of this, the antioxidant and in vitro antibacterial potency of the hydro-e...
Source: Current Drug Delivery - April 19, 2024 Category: Drugs & Pharmacology Authors: Ayesha Bibi Meenakshi Dhanawat Shahbaz Aman Samrat Chauhan Rishabh Chalotra Somdutt Mujwar Narinder Kaur ChamasseHomary Maivagna Sumeet Gupta Source Type: research
The rebirth of epitope-based patent claims
CONCLUSIONS: Companies developing therapeutic antibodies or T cell receptors need to consider these developments in their strategic planning.PMID:38640147 | DOI:10.3233/HAB-240006 (Source: Human Antibodies)
Source: Human Antibodies - April 19, 2024 Category: Biochemistry Authors: Ulrich Storz Source Type: research
Association of Official Racing Chemists guidelines for drug testing in animal hair for doping control
The Association of Official Racing Chemists (AORC) guidelines for drug testing in animal hair provide animal sport doping control laboratories with a framework for the implementation of a robust and legally defensible program for the analysis, both screening and confirmatory, of animal hair samples. AbstractThe Association of Official Racing Chemists (AORC) guidelines for drug testing in animal hair provide animal sport doping control laboratories with a framework for the implementation of a robust and legally defensible program for the analysis, both screening and confirmatory, of animal hair samples. The guidelines were ...
Source: Drug Testing and Analysis - April 19, 2024 Category: Drugs & Pharmacology Authors: Bob Gray,
Ludovic Bailly ‐Chouriberry,
Wai Him Kwok,
Sean Yamada,
Masayuki Yamada,
Benjamin Moeller Tags: TUTORIAL Source Type: research
Supporting Parents in the Prenatal Period in Their Choice to Donate Organs Following the Death of Their Newborn.
1. Understand the potential diagnoses in the newborn period that could potentially contribute to the pool of organs or tissue available for transplant.2. Understand the potential benefit to families who pursue the donation of organs and/or tissue from their newborn. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Terri Weinman, Katie Lawrence Source Type: research
10 Tips to Know About Creating, Operating, and Maintaining a Palliative Care Unit
1. Participants will be able to familiarize themselves with how a strategy to implement a successful palliative care unit.2. Participants will be able to identify anticipated challenges, obstacles, and barriers when operating a PCU, and how to overcome them. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Lawrence Asprec, Elizabeth Capano, Sawudat DeCoteau Source Type: research
