Timing of intraoperative neurophysiological monitoring (IONM) recovery and clinical recovery after termination of pediatric spinal deformity surgery due to loss of IONM signals
Intraoperative neurophysiological monitoring (IONM) is routinely used to reduce the risk of neurological injury during spinal surgery, especially in cases that require deformity correction and instrumentation [1]. Transcranial motor evoked potentials (MEPs) and somatosensory-evoked potentials (SSEPs) allow real time assessment of motor and sensory pathways during surgery, and they have been recognized as reliable early markers in predicting nervous system integrity after spinal surgery [2,3]. (Source: The Spine Journal)
Source: The Spine Journal - April 11, 2024 Category: Orthopaedics Authors: Travis S. CreveCoeur, Rajiv R. Iyer, Hannah E. Goldstein, Mychael W. Delgardo, Todd C Hankinson, Mark A. Erickson, Sumeet Garg, David L Skaggs, Lindsay Andras, Benjamin C. Kennedy, Patrick J. Cahill, Lawrence G. Lenke, Peter D. Angevine, Benjamin D. Roye, Tags: Clinical Study Source Type: research

Recent trends in an uncommon method of carbon monoxide suicide
ConclusionCB suicide is perceived to be widely accessible and painless and is therefore becoming a popular suicide method. Monitoring future trends will be important to determine whether intervention is required. (Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - April 11, 2024 Category: Forensic Medicine Source Type: research

Prognostic model to predict the incidence of radiographic knee osteoarthritis
Conclusion A novel prognostic model based on common clinical variables and protein biomarkers was developed and externally validated to predict rKOA incidence over a 96-month period in individuals without any radiographic signs of disease. The resulting nomogram is a useful tool for stratifying high-risk populations and could potentially lead to personalised medicine strategies for treating OA. (Source: Annals of the Rheumatic Diseases)
Source: Annals of the Rheumatic Diseases - April 11, 2024 Category: Rheumatology Authors: Paz-Gonzalez, R., Balboa-Barreiro, V., Lourido, L., Calamia, V., Fernandez-Puente, P., Oreiro, N., Ruiz-Romero, C., Blanco, F. J. Tags: Open access, ARD, Osteoarthritis Source Type: research

A university cut tenured faculty ’s pay. They’re suing
Along with a secure post and academic freedom, tenured professors enjoy financial security—or so many outsiders imagine. In fact, many tenured faculty are expected to cover much of their salary with grants, and may be penalized with salary reductions if they do not. That’s what happened at Tufts University School of Medicine—and some researchers are fighting back. Last month, the Massachusetts Supreme Judicial Court sent a case brought by eight of the school’s faculty members to trial, writing that their claims have merit : “Tenure would seem to be a hollow promise if it came without any salary co...
Source: Science of Aging Knowledge Environment - April 10, 2024 Category: Geriatrics Source Type: research

A Biophilosophical Approach to the Determination of Brain Death
Chest. 2024 Apr;165(4):959-966. doi: 10.1016/j.chest.2023.12.011.ABSTRACTTechnical and clinical developments have raised challenging questions about the concept and practice of brain death, culminating in recent calls for revision of the Uniform Determination of Death Act (UDDA), which established a whole brain standard for neurologic death. Proposed changes range from abandoning the concept of brain death altogether to suggesting that current clinical practice simply should be codified as the legal standard for determining death by neurologic criteria (even while acknowledging that significant functions of the whole brain...
Source: Chest - April 10, 2024 Category: Respiratory Medicine Authors: Daniel P Sulmasy Christopher A DeCock Carlo S Tornatore Allen H Roberts James Giordano G Kevin Donovan Source Type: research