Journal of Biomedical Materials Research Part B: Applied Biomaterials Journal of Biomedical Materials Research Part B: Applied Biomaterials RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

In vitro biocompatibility of polylactide and polybutylene succinate blends for urethral tissue engineering
AbstractSurgical treatment of urothelial defects with autologous genital or extragenital tissue grafts is susceptible to complications. Tissue engineering utilizing novel biomaterials and cells such as human urothelial cells (hUC) for epithelial regeneration and adipose stromal cells (hASC) for smooth muscle restoration might offer new treatment options for urothelial defects. Previously, polylactide (PLA) has been studied for urethral tissue engineering, however, as such, it is too stiff and rigid for the application. Blending it with ductile polybutylene succinate (PBSu) could provide suitable mechanical properties for t...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - May 18, 2023 Category: Materials Science Authors: Reetta Sartoneva, Inari Lyyra, Maiju Juusela, Vipul Sharma, Heini Huhtala, Jonathan Massera, Minna Kellom äki, Susanna Miettinen Tags: RESEARCH ARTICLE Source Type: research

Electrophoretic deposition of gentamicin and chitosan into titanium nanotubes to target periprosthetic joint infection
AbstractPeriprosthetic joint infection (PJI) occurs in 1% –2% of primary total hip and knee arthroplasties; the rate can reach 20% in individuals at risk. Due to the low local bioavailability of systemic antibiotics and possible off-target effects, localized drug delivery systems are of great importance. Our aim was the electrophoretic deposition (EPD) o f gentamicin and chitosan in Titanium (Ti) nanotubes to establish a local, prolonged antibiotic delivery. Nanotubes were created on Ti wire with a two-step anodization process. For drug deposition, EPD and the air-dry methods were compared. For a prolonged drug release, ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - May 18, 2023 Category: Materials Science Authors: Greta Della Fara, Adrienn Markovics, Simona Radice, John L. Hamilton, Roberto Chiesa, Andreas Sturm, Katja Angenendt, Alfons Fischer, Markus A. Wimmer Tags: RESEARCH ARTICLE Source Type: research

Calcium phosphate incorporated in silk fibroin/methylcellulose based injectable hydrogel: Preparation, characterization, and in vitro biological evaluation for bone defect treatment
In conclusion SF incorporated into composite injectable hydrogel potentially improve biological characteristics and may provide clinical advantages. (Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - May 17, 2023 Category: Materials Science Authors: Premchirakorn Phewchan, Artit Laoruengthana, Waree Tiyaboonchai Tags: RESEARCH ARTICLE Source Type: research

Observations of bony ongrowth and clinical fixation in two retrieved disc replacements
AbstractTotal disc replacements utilize textured coatings to maximize bony ongrowth. However, the contribution of direct bony attachment to overall fixation for total disc replacements has not been reported. The goal of the present study was to document the extent of bony attachment to the surfaces of two clinically functional total disc replacements that were securely fixed at the time of revision. Two metal-and-polymeric disc replacements, one cervical and one lumbar, were evaluated following surgical retrieval. The cervical device was retrieved at 8  months and the lumbar device at 28 months post-operative. Both dev...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - May 17, 2023 Category: Materials Science Authors: Jenna M. Wahbeh, Sang ‐Hyun Park, Sumant Iyer, Edward Ebramzadeh, Sophia N. Sangiorgio Tags: RESEARCH ARTICLE Source Type: research

Bone healing around implants placed in subjects with metabolically compromised systemic conditions
AbstractThe aim of this study was to evaluate the bone healing of tight-fit implants placed in the maxilla and mandible of subjects compromised with metabolic syndrome (MS) and type-2 Diabetes Mellitus (T2DM). Eighteen G öttingen minipigs were randomly distributed into three groups: (i) control (normal diet), (ii) MS (cafeteria diet for obesity induction), (iii) T2DM (cafeteria diet for obesity induction + Streptozotocin for T2DM induction). Maxillary and mandibular premolars and molar were extracted. After 8 w eeks of healing, implants with progressive small buttress threads were placed, and allowed to integrate for ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - May 16, 2023 Category: Materials Science Authors: Edmara T. P. Bergamo, Lukasz Witek, Ilana Ramalho, Adolfo C. O. Lopes, Vasudev Vivekanand Nayak, Estevam A. Bonfante, Nick Tovar, Andrea Torroni, Paulo G. Coelho Tags: RESEARCH ARTICLE Source Type: research

Anatomy, molecular structures, and hyaluronic acid – Gelatin injectable hydrogels as a therapeutic alternative for hyaline cartilage recovery: A review
AbstractCartilage damage caused by trauma or osteoarthritis is a common joint disease that can increase the social and economic burden in society. Due to its avascular characteristics, the poor migration ability of chondrocytes, and a low number of progenitor cells, the self-healing ability of cartilage defects has been significantly limited. Hydrogels have been developed into one of the most suitable biomaterials for the regeneration of cartilage because of its characteristics such as high-water absorption, biodegradation, porosity, and biocompatibility similar to natural extracellular matrix. Therefore, the present revie...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - May 14, 2023 Category: Materials Science Authors: Juan Jairo Vaca ‐González, Juan José Saiz Culma, Lady Marcela Higuera Nova, Diego Alexander Garzón‐Alvarado Tags: REVIEW ARTICLE Source Type: research

A native extracellular matrix material for tissue engineering applications: Characterization of pericardial fluid
In this study, the usability of PF components for the production of an ideal scaffold was investigated. For this aim, pericardial fluid (PF) was harvested from the bovine heart, then its structure and components were characterized. The results of Raman spectroscopy analysis, histological staining, and scanning electron microscopy (SEM) shows that the pericardial fluid contains collagen type I and IV, elastin, fibrin, and glycosaminoglycan (GAG), which are native extracellular matrix (ECM) components. The results demonstrated that (i) PF contains native ECM proteins and GAG such as collagen types I, III, and IV, elastin, an...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - May 12, 2023 Category: Materials Science Authors: Dilek S önmezer, Fatma Latifoğlu, Güler Toprak, Münevver Baran Tags: RESEARCH ARTICLE Source Type: research

Issue Information
(Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - May 10, 2023 Category: Materials Science Tags: ISSUE INFORMATION Source Type: research

Transfection efficacy and drug release depends upon the PEG derivative in cationic lipoplexes: Evaluation in 3D in vitro model and in vivo
AbstractThe goal of the study was to estimate transfection efficacy and drug release in function of the PEG derivative in cationic liposomes and lipoplexes in both 2D and 3D in vitro models as well as in a mouse model (in vivo). For this purpose, cationic PEGylated nanocarriers based on OrnOrnGlu(C16H33)2 lipopeptides were fabricated and characterized. The nanocarriers were loaded with DNA plasmid pGL3 or with siRNA targeting 5 ′-UTR region of Hepatitis C virus, and their transfection efficacies were studied by luciferase test or by PCR technique, respectively. The pGL3-lipoplexes containing PEG derivativeb (6  mol % P...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - May 4, 2023 Category: Materials Science Authors: Gileva A. M., Koloskova O. O., Nosova A. S., Vishniakova L. I., Simonova V. A., Kurbanova L. A., Egorenkov E. A., Smirnov V. V., Budanova U. A., Sebyakin Yu L., Suzina N. E., Khaitov M. R., Markvicheva E. Tags: RESEARCH ARTICLE Source Type: research

The effect of silicon groups on the physicochemical property and bioactivity of L ‐phenylalanine derived poly(amide‐imide)
This study advanced our understanding of silicon modification in PAI can modulate cell responses via initiating silicon concentration regulation. The acquired knowledge will provide a new strategy to design and optimize biomedical PAI in the future. (Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - April 21, 2023 Category: Materials Science Authors: Yaping Hu, Hongbiao Zhang, Qiying Zou, Wenbin Liu, Wenqin Li, Lesan Yan, Honglian Dai Tags: RESEARCH ARTICLE Source Type: research

Low cycle fretting and fretting corrosion properties of low carbon CoCrMo and additively manufactured CoCrMoW alloys for dental and orthopedic applications
The objective of this work was to investigate the low cycle tribological and tribocorrosion characteristics of AM CoCrMoW alloys compared to wrought LC CoCrMo (ASTM F-1537) to assess this AM alloy's performance. Fretting and tribocorrosion testing was performed in air (wear only), PBS (wear  + corrosion), and PBS with 10 mM H2O2 (wear  + corrosion + inflammation) by a single diamond asperity. No variation between alloys in volume of material removed (p = .12), volume of plastic deformation (p = .13), and scratch depth (p = .84) showed that AM was substantially similar in wear resistance to LC in a...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - April 21, 2023 Category: Materials Science Authors: Annsley Mace, Jeremy L. Gilbert Tags: RESEARCH ARTICLE Source Type: research

3D bioprinted osteosarcoma model for experimental boron neutron capture therapy (BNCT) applications: Preliminary assessment
AbstractOsteosarcoma is the most frequently primary malignant bone tumor characterized by infiltrative growth responsible for relapses and metastases. Treatment options are limited, and a new therapeutic option is required. Boron neutron capture therapy (BNCT) is an experimental alternative radiotherapy able to kill infiltrative tumor cells spearing surrounding healthy tissues. BNCT studies are performed on 2D in vitro models that are not able to reproduce pathological tumor tissue organization or on in vivo animal models that are expensive, time-consuming and must follow the 3R's principles. A 3D in vitro model is a solut...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - April 5, 2023 Category: Materials Science Authors: Elena Delgrosso, Franca Scocozza, Laura Cansolino, Federica Riva, Michele Conti, Giada Loi, Ferdinando Auricchio, Ian Postuma, Silva Bortolussi, Lorenzo Cobianchi, Cinzia Ferrari Tags: RESEARCH ARTICLE Source Type: research

Cover Image
The cover image is based on the Research ArticlePhysical, morphological and bioactive properties of Co –Cr–W–Ta alloys: Influence of insertion of tantalum and surface thermochemical treatment on bioactivity by Beatriz da Silva Batista et al.,https://doi.org/10.1002/jbm.b.35229 The cover image is based on the Research ArticlePhysical, morphological and bioactive properties of Co –Cr–W–Ta alloys: Influence of insertion of tantalum and surface thermochemical treatment on bioactivity by Beatriz da Silva Batista et al.,https://doi.org/10.1002/jbm.b.35229 (Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - April 4, 2023 Category: Materials Science Authors: Beatriz da Silva Batista, Luzeli Moreira da Silva, Alan Silva de Menezes, Luana Barbosa Corr êa, Elaine Cruz Rosas, Ralph Santos‐Oliveira, Fernando Mendes, Ana Angélica M. Macêdo, Luciana M. Rebelo Alencar Tags: COVER IMAGE Source Type: research

Issue Information
(Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - April 4, 2023 Category: Materials Science Tags: ISSUE INFORMATION Source Type: research

Three ‐dimensional silk fibroin‐gelatin/chondroitin sulfate/hyaluronic acid–aloe vera scaffold supports in vitro chondrogenesis of bone marrow mesenchymal stem cells and reduces inflammatory effect
In conclusion, based on its superior physical and biological characteristics that support chondrogenesis of BM-MSCs, the SF-GCH-A-411 scaffold is recommended for cartilage tissue engineering. (Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - March 30, 2023 Category: Materials Science Authors: Kritsarut Wuttisiriboon, Patcharaporn Tippayawat, Jureerut Daduang, Temduang Limpaiboon Tags: RESEARCH ARTICLE Source Type: research