Journal of Biomedical Materials Research Part B: Applied Biomaterials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Issue Information
(Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 27, 2023 Category: Materials Science Tags: ISSUE INFORMATION Source Type: research

A study of the role of multiple layer ‐by‐layer assembled bionic extracellular matrix in promoting wound healing via activation of the Wnt signaling pathway
This study adopts the principle of layer-by-layer self-assembly, and the binding force formed by electrostatic attraction and Schiff base was used to combine bFGF and RGD with collagen membrane to form a biomimetic membrane that is non-cytotoxic with stron g biocompatibility that could promote soft tissue healing. The surface characteristics of MLCM and the sustained release concentration of bFGF in vitro were measured, and the effects of MLCM on cell viability, proliferation, migration, and wound healing by means of Wnt/catenin pathways were studied through cell experiments and animal experiments under the comparison of n...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 13, 2023 Category: Materials Science Authors: Zehui Wang, Kun Cao, Di Yan, Yangjing Ge, Ruiyuan Li, Yanwen Liu, Ting Ma, Xiaojuan Sun Tags: RESEARCH ARTICLE Source Type: research

Combining povidone ‐iodine with vancomycin can be beneficial in reducing early biofilm formation of methicillin‐resistant Staphylococcus aureus and methicillin‐sensitive S. aureus on titanium surface
The objectives of this in vitro study were to test the efficacy of povidone-iodine (PVP-I) and vancomycin in treating premature and developedStaphylococcus aureus biofilms grown on titanium implant surfaces. PVP-I and vancomycin were used to treat immature and developed biofilms formed by two clinical strains ofS. aureus (BP043-MRSA, PB011-MSSA).S. aureus strains were grown as immature (3  h-old) or developed (24 h-old) biofilm. These biofilms were grown on titanium plasma sprayed discs. The treatment regimens tested were: 0.8% PVP-I, 500 μg/ml vancomycin as well as a combination of vancomycin and PVP-I. PVP-I was te...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 12, 2023 Category: Materials Science Authors: Mariam Taha, Rozanne Arulanandam, Andrew Chen, Jean ‐Simon Diallo, Hesham Abdelbary Tags: RESEARCH ARTICLE Source Type: research

Biodegradable and antithrombogenic chitosan/elastin blended polyurethane electrospun membrane for vascular tissue integration
In this study, biodegradable vascular membranes were fabricated in a structure of electrospun nanofibers composed of polyurethane (PU), chitosan (CS) and elastin (0.5%, 1.0%, and 1.5%). The physicochemical properties of the membranes were analyzed, followed by the conduction of several test analyses. The blending of CS and elastin has increased the fiber diameter, pore size and porosity percentage with the appearance of identical chemical groups. The wettability of PU membranes was enhanced up to 39.6%, demonstrating higher degradation following the incorporation of both natural polymers. The PU/CS/elastin electrospun memb...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 11, 2023 Category: Materials Science Authors: Thiviya Selvaras, Somyah Ali Alshamrani, Rathosivan Gopal, Saravana Kumar Jaganathan, Sivakumar Sivalingam, Suhaini Kadiman, Syafiqah Saidin Tags: RESEARCH ARTICLE Source Type: research

Characterization in respect to degradation of titanium ‐coated polypropylene surgical mesh explanted from humans
In this study, two explanted Ti-PP mesh samples each having different incorporation durations from two patients were examined. Material analysis conducted within this study includes the following techniques: attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), Raman spectroscopy, low voltage – scanning electron microscopy (LV-SEM), backscattered electron (BSE) imaging, energy dispersive X-ray spectroscopy (EDS) and secondary election hyperspectral imaging (SEHI). The hypothesis of this study is that the Ti coating successfully shields the PP mesh from oxidative stress in vivo and thus protects...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 8, 2023 Category: Materials Science Authors: Nicholas T. H. Farr, Bernd Klosterhalfen, G ünter K. Noé Tags: RESEARCH ARTICLE Source Type: research

Co ‐initiators of polymerization can modulate the inflammatory cytokine release without major cytotoxic effects in human dental pulp cells
AbstractTo evaluate the cytotoxicity of co-initiators of polymerization and its influence on cytokine release from human dental pulp cells (hDPCs). Cells were isolated from the dental pulp of sound human third molars. The co-initiators dimethylaminoethyl amine benzoate —(EDAB), 2-(dimethylamino)ethyl methacrylate (DMAEMA); 2-Ethylhexyl 4-(dimethylamino)benzoate (EHA) and bis(4-methyl phenyl)iodonium hexafluorophosphate (BPI) were diluted in dimethylsulfoxide (DMSO) at different concentrations. In this way, experimental groups and one control (without treatment) were obtained. hDPCs (10  × 104 cell per well) were see...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 5, 2023 Category: Materials Science Authors: B árbara Gabriela Agostinelli, Denise Carleto Andia, Adriano F. Lima Tags: RESEARCH ARTICLE Source Type: research

Antibacterial and biocompatible polyaniline ‐doped titanium oxide layers
The objective of the present study was to determine the proper aniline electrolyte concentration needed to maximize the PCA and reduce bacterial attachment on the formed oxides. Aniline concentrations up to 1  M were added into a 1 M sulfuric acid electrolyte. The formed oxides exhibited increased PANI surface coverage but decreased anatase and rutile crystalline titanium oxide phase formation with increasing aniline electrolyte concentrations. Despite exhibiting the lowest levels of anatase and ruti le formation, the 0.75 M and 1 M aniline oxides with the greatest PANI surface coverage also exhibited the highest PC...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 1, 2023 Category: Materials Science Authors: Aya Ali, Sheetal Chowdhury, Mary A. Carr, Amol V. Janorkar, Mary Marquart, Jason A. Griggs, Joel D. Bumgardner, Michael D. Roach Tags: RESEARCH ARTICLE Source Type: research

Bioactive ZnO ‐assisted 1393 glass scaffold promotes osteogenic differentiation: Some studies
A total of 1393 glass-derived scaffolds (BG and ZnBGs) prepared through sol –gel route were characterized for bone formation in vitro and in vivo. The BMSC showed enhanced osteogenesis in Z3BG than BG and Control. AbstractWe developed ZnO-assisted 1393 bioactive glass-based scaffold with suitable mechanical properties through foam replica technique and observed to be suitable for bone tissue engineering application. However, the developed scaffolds' ability to facilitate cellular infiltration and integration was further assessed through in vivo studies in suitable animal model. Herein, the pure 1393 bioactive glass (BG) ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 31, 2022 Category: Materials Science Authors: Akher Ali, Ankush Paladhi, Sumit Kumar Hira, Bhisham Narayan Singh, Ram Pyare Tags: RESEARCH ARTICLE Source Type: research

In vitro and in vivo effect of novel GA ‐CSNPs loaded col‐fibrin nanocomposite scaffold on diabetic wound healing
AbstractA non-healing wound is a common problem associated with diabetes mellitus. Chronic inflammation, challenging re-epithelization, unusual growth factors, and impaired angiogenesis are the multifactorial events that contribute to impaired wounds. Hence, in the present work, an innovative GA-CSNPs nanocomposite scaffold has been fabricated by integrating Gallic acid (GA) loaded chitosan nanoparticles (GA-CSNPs) into a genipin crosslinked collagen-fibrin (Col-fibrin) scaffold as wound dressing material. The in vitro RT-PCR study carried out using NIH/3T3 mouse fibroblast cells showed that treatment with GA-CSNPs nanocom...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 30, 2022 Category: Materials Science Authors: Pallavi Shyam Kaparekar, Suresh Kumar Anandasadagopan Tags: RESEARCH ARTICLE Source Type: research

A 3D printed hydrogel to promote human keratinocytes' spheroid ‐based growth
AbstractTissue engineering uses cells and biomaterials to develop bioartificial tissue substitutes for different purposes. For example, although several skin models have been developed for pharmaceutical and cosmetic research and skin wound healing, there are few studies on 3D cultures of keratinocytes in 3D printed scaffolds. So, this work aimed to develop a 3D-printed hydrogel scaffold to promote human keratinocyte growth. Mesh 3D scaffolds were printed using an extrusion-based method with a 20% gelatin/5% alginate hydrogel, where HaCaT cells were cultured for 7  days. Scaffolds kept their structure for over 1 week, ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 27, 2022 Category: Materials Science Authors: T ânia Rocha, Ana Margarida Teixeira, Susana G. Gomes, António André, Pedro Martins, João Ferreira, Rita Negrão Tags: RESEARCH ARTICLE Source Type: research

Diamond ‐like carbon films prepared by a low temperature periodic process for application in ventricular assist devices
This study demonstrates the potential of low-temperature DLC films as wear-resistant surface modification for VADs. (Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 22, 2022 Category: Materials Science Authors: Peipei Jing, Meili Zhang, Chris H. H. Chan, Fengjuan Jing, Jo P. Pauls, Matthew S. Dargusch, John F. Fraser, Yongxiang Leng Tags: RESEARCH ARTICLE Source Type: research

Comparative study of the effect of different temperatures on bovine bone used for bone repair of critical calvaria defects in rats
AbstractTo evaluate the osteoconductive potential of inorganic biomaterials of bovine origin submitted to different temperatures in the bone repair of critical defects in rat calvaria. Forty-eight rats were divided into four groups according to the material used to fill the defect: control group (GC), the defect was filled only with blood clot (n = 12); GBO, defect filled with Bio-Oss®, deproteinzed at 300°C (n = 12); GOX, defect filled with Inorganic GenOx®, deproteinzed from 850 to 1200°C (n = 12) and G700, defect filled with Inorganic GenOx 700, deproteinzed at 700°C (n = 12). In each animal's calvaria, a t...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 15, 2022 Category: Materials Science Authors: Lais Sara Egas, Mariza Akemi Matsumoto, Henrique Hadad, Karen Rawen Tonini, Daniela Atili Brandini Weert, Paulo S érgio Perri de Carvalho, Daniela Ponzoni Tags: RESEARCH ARTICLE Source Type: research

Issue Information
(Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 13, 2022 Category: Materials Science Tags: ISSUE INFORMATION Source Type: research

Sterilization effects on poly(glycerol dodecanedioate): A biodegradable shape memory elastomer for biomedical applications
AbstractBiodegradable shape memory polymers provide unique regenerative medicine approaches in minimally invasive surgeries. Once heated, thermally responsive shape memory polymer devices can be compressed, programmed to fit within a small profile, delivered in the cold programmed state, and expanded when heated to body temperature. We have previously developed a biodegradable shape memory elastomer (SME), poly(glycerol dodecanedioate) (PGD), with transition temperatures near 37 °C exhibiting nonlinear elastic properties like numerous soft tissues. Using SMEs in the clinic requires disinfection and sterilization methods t...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 9, 2022 Category: Materials Science Authors: Harsha Ramaraju, Annabel M. McAtee, Ryan E. Akman, Adam S. Verga, Martin L. Bocks, Scott J. Hollister Tags: RESEARCH ARTICLE Source Type: research