Journal of Biomedical Materials Research Part B: Applied Biomaterials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Development of a novel PLDLA/ β‐TCP composite‐based biodegradable anterior cervical plate and screw system
AbstractWe investigated the effectiveness and safety of a new composite-based biodegradable anterior cervical plate/screw (ACPS) system for the anterior cervical discectomy and fusion (ACDF) fixation. A biocomposite in combination with 30  wt% β-tricalcium phosphate (β-TCP; a biodegradable ceramic having osteoconductive ability) and 70 wt% poly-l/d-lactide copolymer (PLDLA; a biodegradable polymer) was developed and used in the ACPS device, comprising one plate and four screws for fixation. Based on a literature review, a clinically required period of performance maintenance was set as 16  weeks, and to verify the ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - September 6, 2023 Category: Materials Science Authors: Younghoon Kwon, Mosharraf Hossain, Minsu Lee, Je Hoon Jeong Tags: RESEARCH ARTICLE Source Type: research

Issue Information
(Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - September 1, 2023 Category: Materials Science Tags: ISSUE INFORMATION Source Type: research

Comparison of PLLA ‐PEG and PDLLA‐PEG micelles for co‐encapsulation of docetaxel and resveratrol
This article presents a comparison of single- (Dtx or Res) and dual-drug (Dtx and Res) loaded micelles obtained from poly(l,l-lactide)-co-poly(ethylene glycol) (PLLA-PEG) and poly(d,l-lactide)-co-poly(ethylene glycol) (PDLLA-PEG). The analyzes of the micelles have been conducted including morphology, drug(s) encapsulation efficiency, intermolecular interactions, in vitro drug release, and cytotoxicity. Differences in drug loading ability and release profile have been observed between Res and Dtx but also depending on the polymer and number of drugs in micelles (single vs. dual loaded). The PLLA-PEG micelles have a signific...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - September 1, 2023 Category: Materials Science Authors: Magdalena Jurczyk, Monika Musia ł‐Kulik, Aleksander Foryś, Marcin Godzierz, Bożena Kaczmarczyk, Janusz Kasperczyk, Dorota Wrześniok, Artur Beberok, Katarzyna Jelonek Tags: RESEARCH ARTICLE Source Type: research

Synthesis, characterization, mechanical and magnetic characteristics of Gd3+/PO43 − substituted zircon for application in hard tissue replacements
AbstractThe study reports on the use of sol –gel technique to yield zircon type [Zr(1 –0.1–x) GdxTi0.1] [(SiO4)1 –x(PO4)x] solid solution. Titanium has been used as a mineralizer to trigger zircon formation while equimolar concentrations of Gd3+ and PO43 − were added to determine their accommodation limits in the zircon structure. The crystallization oft-ZrO2 as a dominant phase alongside the crystallization ofm-ZrO2 and zircon were detected at 1200 °C while their further annealing revealed the formation of zircon as a major phase at 1300°C. Heat treatment at 1400°C revealed the formation of zircon-type solid ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 29, 2023 Category: Materials Science Authors: Ezhilan M, M. Mushtaq Alam, U. Vijayalakshmi, Somlee Gupta, Arunkumar Dhayalan, S. Kannan Tags: RESEARCH ARTICLE Source Type: research

Design and development of a patient ‐specific temporomandibular joint implant: Probing the influence of bone condition on biomechanical response
This study addresses these limitations by examining the influence of patient-specific design concepts and bone conditions on TMJ implant performance. Clinical evidences support the importance of implant design on healing ability. Previous studies have focused on achieving precise implant fit based on geometric considerations, however those published studies did not explore the impact of such. Against this perspective, the present study reports the extensive finite element analysis (FEA) results, while analyzing the impact of a newly designed patient-specific TMJ implant to address clinical complications associated with var...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 26, 2023 Category: Materials Science Authors: Anik Banerjee, Bikramjit Basu, Subrata Saha, Amit Roy Chowdhury Tags: RESEARCH ARTICLE Source Type: research

Development of cobalt (Co) ‐doped monetites for bone regeneration
AbstractCobalt-doped monetite powders were synthesized by coprecipitation method under a cobalt nominal content between 2 and 20  mol % of total cation. Structural characterization of samples was performed by using X-ray diffraction (XRD), Fourier transform infrared spectroscopy, scanning electron microscopy, and energy dispersive X-ray spectroscopy. XRD results indicated that the Co-doped samples exhibited a monetite singl e-phase with the cell parameters and crystallite size dependent on the amount of substitutional element incorporated into the triclinic crystalline structure. Cell viability and adhesion assays using ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 23, 2023 Category: Materials Science Authors: Gerson Santos Almeida, Marcel Rodrigues Ferreira, C élio Junior Costa Fernandes, Luísa Camilo Suter, Maria Gabriela Jacheto Carra, Diego Rafael Nespeque Correa, Elidiane Cipriano Rangel, Margarida Juri Saeki, Willian Fernando Zambuzzi Tags: RESEARCH ARTICLE Source Type: research

Accelerated in vitro oxidative degradation testing of polypropylene surgical mesh
(Top) Schematic of the automated reactive accelerated aging (aRAA) system. (Bottom Left) Oxidation kinetics of 4 surgical mesh evaluated using FTIR. (Bottom Right) Representative SEM image of a 3-week aRAA aged surgical mesh sample. AbstractPolypropylene (PP) surgical mesh had reasonable success in repair of hernia and treatment of stress urinary incontinence (SUI); however, their use for the repair of pelvic organ prolapse (POP) resulted in highly variable results with lifelong complications in some patients. One of several factors that could be associated with mesh-related POP complications is changes in the properties o...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 20, 2023 Category: Materials Science Authors: Tanmay Jain, Chinnapatch Tantisuwanno, Arindam Paul, Pavel Takmakov, Abraham Joy, Irada Isayeva, David D. Simon Tags: RESEARCH ARTICLE Source Type: research

Indocyanine green and iohexol loaded hydroxyapatite in poly(L ‐lactide‐co‐caprolactone)‐based composite for bimodal near‐infrared fluorescence‐ and X‐ray‐based imaging
This study aimed to develop material for multimodal imaging by means of X-ray and near-infrared containing FDA- and EMA-approved iohexol and indocyanine green (ICG). The mentioned contrast agents (CAs) are hydrophilic and amphiphilic, respectively, which creates difficulties in fabrication of functional polymeric composites for fiducial markers (FMs) with usage thereof. Therefore, this study exploited for the first time the possibility of enhancing the radiopacity and introduction of the NIR fluorescence of FMs by adsorption of the CAs on hydroxyapatite (HAp) nanoparticles. The particles were embedded in the poly(L-lactide...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 19, 2023 Category: Materials Science Authors: Żaneta Górecka, Joanna Idaszek, Marcin Heljak, Diana C. Martinez, Emilia Choińska, Zbigniew Kulas, Wojciech Święszkowski Tags: RESEARCH ARTICLE Source Type: research

Physicochemical and biological analysis of composite biomaterials containing hydroxyapatite for biological applications
AbstractBone tissue regeneration is one of the main areas of tissue engineering. A particularly important aspect is the development of new innovative composite materials intended for bone tissue engineering and/or bone substitution. In this article, the synthesis and characterization of ceramic-polymer composites based on polyvinylpyrrolidone, poly(vinyl alcohol) and hydroxyapatite (HAp) have been presented. The first part of the work deals with the synthesis and characterization of the ceramic phase. It was demonstrated that the obtained calcium phosphate is characterized by a heterogeneity and porosity indicating simulta...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 19, 2023 Category: Materials Science Authors: Magdalena Ba ńkosz, Mateusz M. Urbaniak, Aleksandra Szwed, Karolina Rudnicka, Marcin Włodarczyk, Anna Drabczyk, Sonia Kudłacik‐Kramarczyk, Bożena Tyliszczak, Agnieszka Sobczak‐Kupiec Tags: RESEARCH ARTICLE Source Type: research

Chlorinated ‐based bioceramics incorporated in polycaprolactone membranes
This study presents a promising approach for the development of bioactive membranes for bone tissue engineering, with potential applications in bone regeneration therapies. (Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 18, 2023 Category: Materials Science Authors: Carolina Curcio Lott Guimar ães, Joyce Rodrigues Souza, Tiago Moreira Bastos Campos, Thays Oliveira Marques, Letícia Terumi Kito, Elisa Camargo Kukulka, Luana Marotta Reis Vasconcellos, Alexandre Luiz Souto Borges, Gilmar Patrocínio Thim Tags: RESEARCH ARTICLE Source Type: research

Development of heparinized and hepatocyte growth factor ‐coated acellular scaffolds using porcine carotid arteries
In conclusion, heparinized and HGF-coated acellular porcine carotid arteries may be a promising biological scaffold for tissue-engineered vascular grafts. (Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 17, 2023 Category: Materials Science Authors: Jin Cheng, Cong Wang, Lianrui Guo, Yongquan Gu Tags: RESEARCH ARTICLE Source Type: research

Preparation and comparison of two medical dressings made from the collagens from fish and bovine
AbstractCollagen is used in medical dressings because of its high hydrophilicity, low immunogenicity, excellent biocompatibility, and degradability. These features can promote cell proliferation and platelet agglomeration. Herein, we studied the preparation of gel dressing by using silver carp skin collagen and bovine collagen as raw materials. Their properties and the application effects of collagen gel dressing were evaluated and compared. The centrifugal stability, rheology, and water-loss rate of silver carp skin collagen gel (SCG) and bovine tendon collagen gel (CTG) were determined. Results showed that the two gels w...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 15, 2023 Category: Materials Science Authors: Yaru Sun, Zeyu Wei, Ke Wang, Tianyue Xu, Rui Duan, Junjie Zhang Tags: RESEARCH ARTICLE Source Type: research

An injectable bioactive poly( γ‐glutamic acid) modified magnesium phosphate bone cement for bone regeneration
AbstractAs potential alternatives for calcium phosphate bone cements, magnesium phosphate bone cements (MPC) have attracted considerable attention in recent years. However, their several defects, such as rapid setting times, highly hydration temperature and alkaline pH due to the part of the unreacted phosphate, restricted their applications in human body. With aim to overcome these defects, a novel polypeptite poly( γ-glutamic acid) (γ-PGA) modified MPC were developed. Effect of γ-PGA content on the injectability, anti-washout ability, setting times, hydration temperature, mechanical compressive strength,in vitro bioac...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 14, 2023 Category: Materials Science Authors: Qinwei Yang, Jiadong Zhu, Jing Chen, Peizhi Zhu, Chunxia Gao Tags: RESEARCH ARTICLE Source Type: research

Sacrificial biomaterials in 3D fabrication of scaffolds for tissue engineering applications
AbstractThree-dimensional (3D) printing technology has progressed exceedingly in the area of tissue engineering. Despite the tremendous potential of 3D printing, building scaffolds with complex 3D structure, especially with soft materials, still exist as a challenge due to the low mechanical strength of the materials. Recently, sacrificial materials have emerged as a possible solution to address this issue, as they could serve as temporary support or templates to fabricate scaffolds with intricate geometries, porous structures, and interconnected channels without deformation or collapse. Here, we outline the various types ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 13, 2023 Category: Materials Science Authors: Chi Wang, Yingge Zhou Tags: REVIEW ARTICLE Source Type: research

Chitosan thread in the healing of the cecal wall of rabbits (Oryctolagus cuniculus) submitted to cecorrhaphy
AbstractThe development and evaluation of synthesis materials are crucial to reducing the morbidity and magnitude of post-enterorrhaphy surgical complications. Despite the possibility of production, chitosan thread has not yet been used in enterorrhaphy, and its effects on intestinal healing have not been evaluated. Therefore, this study aimed to evaluate the effects of chitosan thread on the intestinal wall repair of rabbits submitted to cecorrhaphy. For this, 42 rabbits were allocated into two groups with 21 animals. One group was submitted to cecorrhaphy with chitosan suture thread (CG) and the other with poliglecaprone...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 12, 2023 Category: Materials Science Authors: S. H. Ávila Filho, V. M. B. D. Moura, P. J. B. Queiroz, M. B. R. Faleiro, B. S. G. Lima, S. L. R. Freitas, A. S. Santos, L. A. F. Silva Tags: RESEARCH ARTICLE Source Type: research