Journal of Biomedical Materials Research Part B: Applied Biomaterials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Sarcococca saligna fabricated gold nanoparticles alleviated in vitro oxidative stress and inflammation in human adipose ‐derived stem cells
This study was carried out to evaluate the anti-inflammatory and antioxidant potential of bio fabricated GNPs withSarcococca saligna (S. saligna) extract on injured human adipose-derived Mesenchymal stem cells (hADMSCs). GNPs were characterized by ultraviolet –visible (UV–Vis) spectroscopy, Scanning Electron Microscopy (SEM), x-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and energy dispersive x-ray (EDS). Phytochemical screening of biosynthesized GNPs exhibited a significant release of polyphenols, that is, total phenolic c ontent (TPC) and total flavonoid content (TFC). GNPs priming amended ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 11, 2023 Category: Materials Science Authors: Nadia Naseer, Muhammad Munam Mustafa, Noreen Latief, Numan Fazal, Muhammad Tariq, Afshan Afreen, Faiza Yaqub, Sheikh Riazuddin Tags: RESEARCH ARTICLE Source Type: research

Correction to “Human small intestine cancer cell membrane‐camouflaged quercetin‐melanin for antibacterial and antitumor activity”
(Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 5, 2023 Category: Materials Science Tags: CORRECTION Source Type: research

G/ β‐ TCP composite scaffold material promotes osteogenic differentiation of bone marrow mesenchymal stem cells
AbstractTo explore self-made graphene/ β Graphene (G)/β- tricalcium phosphate, G/β- The effect of TCP composite scaffold material on osteogenic differentiation of BMSC. Preparation of G/β- TCP composite material was used to investigate the effect of composite material on bone marrow mesenchymal stem cell ossification/β- TCP material was used to treat primary BMSCs of rats. Cell morphology changes were observed under scanning electron microscopy, cell cycle and proliferation were detected by flow cytometry, and gene expression of chondrogenic genes Fibronectin, collagen I, collagen II, ICAM, and VCAM was detected by q-...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 3, 2023 Category: Materials Science Authors: Hairong Su, Yong Liao, Xiaolu Yuan, Jianhui Huang, Ya Chen, Binxiu Zhao Tags: RESEARCH ARTICLE Source Type: research

Issue Information
(Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 1, 2023 Category: Materials Science Tags: ISSUE INFORMATION Source Type: research

In vitro evaluation of cytotoxicity and genotoxicity of porous nickel titanium dental implants produced by metal injection molding technique
AbstractPorous NiTi (pNiTi) is a promising biomaterial for functional long-term implantation that has been produced using various manufacturing techniques and tested for biocompatibility. pNiTi produced using a more recent technology of Metal Injection Molding (MIM) has shown better physical and mechanical properties than those produced by earlier manufacturing methods, but its biocompatibility has yet to be determined. Hence, extracts from pNiTi dental implants produced by MIM were tested for cytotoxicity and genotoxicity in this work. Its toxicity was evaluated at the cellular and in vitro levels using elution and 3-(4,5...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 1, 2023 Category: Materials Science Authors: Mustafa N. W. N. A., Ahmad R., Kamar Affendi N. H., Sulaiman E., Khushaini M. A. A., Ismail M. H., Teh L. K., Salleh M. Z. Tags: RESEARCH ARTICLE Source Type: research

Predicting partitioning from low density polyethylene to blood and adipose tissue by linear solvation energy relationship models
AbstractThe variety of polymers utilized in medical devices demands for testing of extractables and leachables according to ISO 10993-18:2020 in combination with ISO 10993-1:2018. The extraction of the materials involves the use of organic solvents as well as aqueous buffers to cover a wide range of polarity and pH-values, respectively. To estimate patient exposure to chemicals leaching from a polymer in direct body contact, simulating solvents are applied to best mimic the solubilization and partitioning behavior of the related tissue or body fluid. Here we apply linear solvation energy relationship (LSER) models to predi...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - July 28, 2023 Category: Materials Science Authors: Nadin Ulrich, Alexander B öhme, Adrian Benedict Strobel, Thomas Egert Tags: RESEARCH ARTICLE Source Type: research

Carbon fiber: Characterization and evaluation of the inflammatory response and toxicity in rats
This study aimed to evaluate the Carbon Fiber obtained from PAN textile and cotton fiber in their different forms of presentation: non-activated carbon fiber felt (NACFF), activated carbon fiber felt (ACFF), silver activated carbon fiber felt (Ag-ACFF), and activated carbon fiber tissue (ACFT), to obtain scaffolds as a potential material with properties related to the synthetic bone graft. Characterization tests performed: surface wettability, traction, swelling, and in vivo tests: evaluation of the inflammatory response by implanting the materials in the subcutaneous tissue of 14 Wistar rats, evaluation of collagen fibers...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - July 23, 2023 Category: Materials Science Authors: Clarissa Carvalho Martins Maciel, Let ícia Cavassini Torquato, Eduardo Antonio Chelin Suárez, Kauê Alberto Pereira, Maria Aparecida Neves Jardini, Alexandre Luiz Souto Borges, Luana Marotta Reis Vasconcellos, Jossano Saldanha Marcuzzo, Andrea C Tags: RESEARCH ARTICLE Source Type: research

Structure and properties of the acellular porcine cornea irradiated with electron beam and its in ‐situ implantation
AbstractDifferent sterilization doses of the electron beam (E-beam) will change the properties of biomaterials and affect their clinical application. Acellular porcine cornea (APC) is a promising corneal substitute to alleviate the shortage of corneal resources. The residual DNA was significantly reduced to 18.50  ± 3.19 ng/mg, and the clearance rate of α-Gal was close to 100% after the treatment with freezing–thawing combined enzyme, indicating that the decellularization was effective. The effects of different E-beam doses at 0, 2, 8, 15, and 25 kGy on the APC were studied. With the increase in irradiation dos...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - July 22, 2023 Category: Materials Science Authors: Qing Li, Yajun Sun, Haibin Zhao, Zhiyong Gao, Dongjie Zhai Tags: RESEARCH ARTICLE Source Type: research

Osteogenic differentiation and reconstruction of mandible defects using a novel resorbable membrane: An in vitro and in vivo experimental study
AbstractTo evaluate the cellular response of both an intact fish skin membrane and a porcine-derived collagen membrane and investigate the bone healing response of these membranes using a translational, preclinical, guided-bone regeneration (GBR) canine model. Two different naturally sourced membranes were evaluated in this study: (i) an intact fish skin membrane (Kerecis Oral ®, Kerecis) and (ii) a porcine derived collagen (Mucograft®, Geistlich) membrane, positive control. For thein vitro experiments, human osteoprogenitor (hOP) cells were used to assess the cellular viability and proliferation at 24, 48, 72, and 168 �...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - July 21, 2023 Category: Materials Science Authors: Edmara T. P. Bergamo, Ísis de Fátima Balderrama, Marcel Rodrigues Ferreira, Robert Spielman, Blaire V. Slavin, Andrea Torroni, Nick Tovar, Vasudev V. Nayak, Benjamin R. Slavin, Paulo G. Coelho, Lukasz Witek Tags: RESEARCH ARTICLE Source Type: research

Comparative proteomic analysis of regenerative acellular matrices: The effects of tissue source and processing method
AbstractAcellular tissue matrices are used in regenerative medicine from weak tissue re-enforcement to cosmetic augmentation. However, proteomic signatures leading to different clinical outcomes among matrices are not well understood. In an attempt to investigate the effects of tissue source and processing method, we examined by liquid chromatography tandem mass spectrometry (LC –MS/MS) the proteomic profiles of 12 regulatory agency-approved acellular matrices (AlloMax, AlloDerm, CollaMend, Heal-All, JayyaLife, ReGen, Renov, Strattice, SurgiMend, Surgisis, UniTrump and Vidasis). The compositions of acellular matrices va...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - July 20, 2023 Category: Materials Science Authors: Huidan Wang, Wendell Q. Sun Tags: RESEARCH ARTICLE Source Type: research

Issue Information
(Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - July 4, 2023 Category: Materials Science Tags: ISSUE INFORMATION Source Type: research

Optimizing fabrication parameters via Taguchi method for production of high yield hydroxyapatite microsphere scaffolds using Drop ‐on‐Demand inkjet method
AbstractDrop on demand (DOD) inkjet method is a cost-efficient way of producing hydroxyapatite (HAp) microsphere scaffolds with narrow size distribution. However, DOD fabrication parameters may influence the yield and characteristics of the microsphere scaffolds. Testing different permutations and combinations of fabrication parameters is costly and time consuming. Taguchi method could be used as a predictive tool for optimizing the key fabrication parameters to produce HAp microspheres with desired yield and properties, minimizing the number of experimental combinations to be tested. The aim of this study is to investigat...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - June 29, 2023 Category: Materials Science Authors: Chien Yi Wee, Quentin Ray Tjieh Lim, Yun Zhao, Xin Xu, Zhijie Yang, Dong Wang, Eng San Thian Tags: RESEARCH ARTICLE Source Type: research

Injectable and self ‐healing dual crosslinked gelatin/kappa‐carrageenan methacryloyl hybrid hydrogels via host‐guest supramolecular interaction for wound healing
Gelatin/kappa-carrageenan-based self-healing dual crosslinked hybrid hydrogel for wound healing. AbstractInjectable hydrogels based on natural polymers have shown great potential for various tissue engineering applications, such as wound healing. However, poor mechanical properties and weak self-healing ability are still major challenges. In this work, we introduce a host-guest (HG) supramolecular interaction between acrylate- β-cyclodextrin (Ac-β-CD) conjugated on methacrylated kappa-carrageenan (MA-κ-CA) and aromatic residues on gelatin to provide self-healing characteristics. We synthesize an MA-κ-CA to conjugate Ac...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - June 24, 2023 Category: Materials Science Authors: Dilara Yilmaz ‐Aykut, Gulsah Torkay, Alper Kasgoz, Su Ryon Shin, Ayca Bal‐Ozturk, Huseyin Deligoz Tags: RESEARCH ARTICLE Source Type: research

Engineering a multicompartment in vitro model for dorsal root ganglia phenotypic assessment
AbstractDespite the significant global prevalence of chronic pain, current methods to identify pain therapeutics often fail translation to the clinic. Phenotypic screening platforms rely on modeling and assessing key pathologies relevant to chronic pain, improving predictive capability. Patients with chronic pain often present with sensitization of primary sensory neurons (that extend from dorsal root ganglia [DRG]). During neuronal sensitization, painful nociceptors display lowered stimulation thresholds. To model neuronal excitability, it is necessary to maintain three key anatomical features of DRGs to have a physiologi...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - June 17, 2023 Category: Materials Science Authors: Sydney M. Caparaso, Adan L. Redwine, Rebecca A. Wachs Tags: RESEARCH ARTICLE Source Type: research

Decellularized bladder as scaffold to support proliferation and functionality of insulin ‐secreting pancreatic cells
In this study, a cell culture system has been designed to study the effect of decellularized porcine bladder pieces on INS-1 cells, a cell line secreting insulin in resp onse to glucose stimulation. Porcine bladders were decellularized using two techniques: a detergent-containing and a detergent-free methods. The resulting ECMs were characterized for the removal of both cells and dsDNA. INS-1 cells were not viable on ECM produced using detergent (i.e., sodium dodecyl sulfate). INS-1 cells were visualized following 7  days of culture on detergent-free decellularized bladders using a cell viability and metabolism assay (MT...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - June 13, 2023 Category: Materials Science Authors: Vignesh Dhandapani, Patrick Vermette Tags: RESEARCH ARTICLE Source Type: research