Journal of Biomedical Materials Research Part B: Applied Biomaterials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Cellulose nanocrystals ‐reinforced dual crosslinked double network GelMA/hyaluronic acid injectable nanocomposite cryogels with improved mechanical properties for cartilage tissue regeneration
The objective of the current study is to produce a highly porous injectable scaffold with improved mechanical properties. For this aim, cellulose nanocrystals-reinforced dual crosslinked porous nanocomposite cryogels were prepared using chemically crosslinked methacrylated gelatin (GelMA) and ionically crosslinked hyaluronic acid (HA) through the cryogelation process. The resulting nanocomposites showed highly porous structures with interconnected porosity (>90%) and mean pore size in the range of 130 –296 μm. The prepared nanocomposite containing 3%w/v of GelMA, 20 w/w% of HA, and 1%w/v of CNC showed the highest Y...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - February 1, 2024 Category: Materials Science Authors: Farinaz Jonidi Shariatzadeh, Atefeh Solouk, Hamid Mirzadeh, Shahin Bonakdar, Davoud Sadeghi, Shadab Bagheri Khoulenjani Tags: RESEARCH ARTICLE Source Type: research

Development, characterization, and biological study of bioglass coatings 45S5 and BioK on zirconia implant surfaces
This study aimed to evaluate the effect of coating zirconia implants with two bioactive glasses, 45S5 and BioK, on osteogenesis in vitro and osseointegration in vivo. Zirconia samples and implants were prepared using Zpex zirconia powder and blocks, respectively. The samples were divided into three groups: polished zirconia (ZRC), zirconia coated with 45S5 bioglass (Z  + 45S5), and zirconia coated with BioK glass (Z + BK). Coatings were applied using a brush and sintered at 1200°C. Chemical analysis of the coatings was carried out using x-ray diffraction and Fourier Transform Infrared Spectroscopy. Surface topogra...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - February 1, 2024 Category: Materials Science Authors: Sarah de Oliveira Marco Avelino, Leonardo Alvares Sobral ‐Silva, Gilmar Patrocínio Thim, Luis Augusto de Almeida‐Silva, Juliana dos Santos Lupp, Tiago Moreira Bastos Campos, Luana Marotta Reis de Vasconcellos Tags: RESEARCH ARTICLE Source Type: research

Thermoplastic polyurethane/POSS nanohybrids: Synthesis, morphology, and biological properties
AbstractRecent studies show good osteoinductive properties of polyurethanes modified with polyhedral oligomeric silsesquioxanes (POSS). In this work, three types of POSS; propanediolisobutyl-POSS (PHI-POSS), disilanolisobutyl-POSS (DSI-POSS), and octahydroxybutyl-POSS (OCTA-POSS) were chemically incorporated into linear polyurethane based on an aliphatic isocyanate, hexamethylene diisocyanate (HDI), to obtain new nanohybrid PU-POSS materials. The full conversion of POSS was confirmed by Fourier transform infrared spectroscopy (FTIR-ATR) spectra of the model reactions with pure HDI. The materials obtained were investigated ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - February 1, 2024 Category: Materials Science Authors: Jan Ozimek, Katarzyna Malarz, Anna Mrozek ‐Wilczkiewicz, Edyta Hebda, Krzysztof Pielichowski Tags: RESEARCH ARTICLE Source Type: research

Novel surface biochemical modifications of urinary catheters to prevent catheter ‐associated urinary tract infections
AbstractMore than 70% of hospital-acquired urinary tract infections are related to urinary catheters, which are commonly used for the treatment of about 20% of hospitalized patients. Urinary catheters are used to drain the bladder if there is an obstruction in the tube that carries urine out of the bladder (urethra). During catheter-associated urinary tract infections, microorganisms rise up in the urinary tract and reach the bladder, and cause infections. Various materials are used to fabricate urinary catheters such as silicone, polyurethane, and latex. These materials allow bacteria and fungi to develop colonies on thei...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 26, 2024 Category: Materials Science Authors: Mohammad Sadegh Safari, Hassan Mohabatkar, Mandana Behbahani Tags: REVIEW ARTICLE Source Type: research

Advancements in 3D ‐printed artificial tendon
AbstractMillions of people have been reported with tendon injuries each year. Unfortunately, Tendon injuries are increasing rapidly due to heavy exercise and a highly aging population. In addition, the introduction of 3D-printing technology in the area of tendon repair and replacement has resolved numerous issues and significantly improved the quality of artificial tendons. This advancement has also enabled us to explore and identify the most effective combinations of biomaterials that can be utilized in this field. This review discusses the recent development of the 3D-printed artificial tendon; where recently, some resea...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 23, 2024 Category: Materials Science Authors: Ahmad Alhaskawi, Haiying Zhou, Yanzhao Dong, Xiaodi Zou, Sohaib Hasan Abdullah Ezzi, Vishnu Goutham Kota, Mohamed Hasan Abdulla Abdulla, Tian Tu, Olga Alenikova, Sahar Abdalbary, Hui Lu Tags: REVIEW ARTICLE Source Type: research

Enhancing osseointegration of titanium implants through MC3T3 ‐E1 protein‐gelatin polyelectrolyte multilayers
In this study, the bioactive substance MC3T3-E1 protein-gelatin polyelectrolyte multilayers were constructed on the surface of the titanium implants by means of layer-by-layer self-assembly to enhance the strength of the bond between the bone tissue and the implant. The findings of the study indicate that the layer-by-layer self-assembly technique can enhance surface roughness and hydrophilicity to a considerable extent. Compared to pure titanium, the hydrophilicity of TiOH LBL was significantly increased with a water contact angle of 75.0  ±$$ \pm $$2.4°. The modified titanium implant exhibits superior biocompatibilit...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 22, 2024 Category: Materials Science Authors: Xuhong He, Chaiqiong Guo, Yuhui Wang, Shilong Ma, Xuanyu Liu, Yan Wei, Haofeng Xu, Ziwei Liang, Yinchun Hu, Liqin Zhao, Xiaojie Lian, Di Huang Tags: RESEARCH ARTICLE Source Type: research

S ‐Nitroso‐N‐acetylpenicillamine impregnated latex: A new class of barrier contraception for the prevention of intercourse‐associated UTIs
AbstractUrinary tract infections (UTIs) are some of the most common infections seen in humans, affecting over half of the female population. Though easily and quickly treatable, if gone untreated for too long, UTIs can lead to narrowing of the urethra as well as bladder and kidney infections. Due to the disease potential, it is crucial to mitigate the development of UTIs throughout healthcare. Unfortunately, sexual activity and the use of condoms have been identified as common risk factors for the development of sexually acquired UTIs. Therefore, this study outlines a potential alteration to existing condom technology to d...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 22, 2024 Category: Materials Science Authors: Sarah N. Wilson, Patrick Maffe, Jitendra Pant, Bryan M. Grommersch, Hitesh Handa Tags: RESEARCH ARTICLE Source Type: research

Sintered fluorapatite scaffolds as an autograft ‐like engineered bone graft
AbstractHydroxyapatite (HA)-based materials are widely used as bone substitutes due to their inherent biocompatibility, osteoconductivity, and bio-absorption properties. However, HA scaffolds lack compressive strength when compared to autograft bone. It has been shown that the fluoridated form of HA, fluorapatite (FA), can be sintered to obtain this desired strength as well as slower degradation properties. Also, FA surfaces have been previously shown to promote stem cell differentiation toward an osteogenic lineage. Thus, it was hypothesized that FA, with and without stromal vascular fraction (SVF), would guide bone heali...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 22, 2024 Category: Materials Science Authors: Clark Nielson, Jayant Agarwal, James Peter Beck, Jill Shea, Sujee Jeyapalina Tags: RESEARCH ARTICLE Source Type: research

Issue Information
(Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 20, 2024 Category: Materials Science Tags: ISSUE INFORMATION Source Type: research

Bacterial cellulose as a promising material for pulmonary valve prostheses: In vivo study in a sheep model
ConclusionsThis pilot study provides evidence that bacterial cellulose may be suitable for pulmonary valve prostheses and surgical pulmonary artery plasty. Further studies on the high pressure side of the left heart are needed. (Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 14, 2024 Category: Materials Science Authors: Piotr Siondalski, Magdalena Ko łaczkowska, Michał Bieńkowski, Rafał Pęksa, Maciej M. Kowalik, Kinga Dawidowska, Katrien Vandendriessche, Bart Meuris Tags: RESEARCH ARTICLE Source Type: research

Attachment and proliferation of human gingival fibroblasts seeded on barrier membranes using Wharton's jelly ‐derived stem cells conditioned medium: An in vitro study
In this study, human gingival fibroblasts were prepared and cultured on three membranes: collagen membrane, acellular dermal matrix (ADM) with ZnO-NPs, and ADM without ZnO-NPs. WJMSCs-CM was given to the testing groups, while control groups received the same membranes without WJMSCs-CM. Following 48 and 72  h, 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) tests were performed to assess cell survival. Cell proliferation on the membranes was also evaluated using 4′,6-diamidino-2-phenylindole (DAPI) staining after 48 and 72 h. Field emission scanning electron microscopy was use d to determine membra...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 9, 2024 Category: Materials Science Authors: Mohammadreza Karimi, Seyed Ali Mosaddad, Seyedeh Sara Aghili, Hengameh Dortaj, Seyedeh ‐Sara Hashemi, Farin Kiany Tags: RESEARCH ARTICLE Source Type: research

Electrospun nylon 6/hyaluronic acid/chitosan bioactive nanofibrous composite as a potential antibacterial wound dressing
In this study, HA and CS were applied to modify N6 nanofibrous mat (N6/HA/CS) for potential wound dressing. N6/HA/CS nanofibrous composite mats were developed using a simple one-step electrospinning technique at different CS concentrations of 1, 2, and 3  wt%. The results demonstrated that incorporating HA and CS into N6 resulted in increased hydrophilicity, as well as favorable physical and mechanical properties. In addition, the minimum inhibitory concentration and (MIC) optical density techniques were used to determine the antibacterial propert ies of N6/HA/CS nanofibrous composite mats, and the results demonstrated t...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 8, 2024 Category: Materials Science Authors: Amin Foroozandeh, Mohamadreza Shakiba, Amirhosein Zamani, Alireza Tajiki, Mehdi Sheikhi, Mehrab Pourmadadi, Zohreh Pahnavar, Erfan Rahmani, Nafiseh Aghababaei, Hossein Salar Amoli, Majid Abdouss Tags: RESEARCH ARTICLE Source Type: research

Efficacy of collagen conduit wrapping with collagen fibers on nerve regeneration in sciatic nerve injury with partial transection: An experimental study in the rat model
AbstractPeripheral nerve injuries (PNIs) include complete and partial transection, crushing, and chronic compression injuries. Hollow absorbable conduits are used to treat complete transection with short defects, while wrapping the injured part with an absorbent material promotes nerve recovery by inhibiting inflammatory cell infiltration and scar tissue formation in crush injuries. For treatment of partially transected nerve injuries (PTNIs), such as injection-related iatrogenic PNI, whether wrapping the entire nerve, including the injury site, or bridging the transected fascicle with an artificial nerve conduit (ANC) is ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 6, 2024 Category: Materials Science Authors: Hiromasa Tanaka, Shigeru Kurimoto, Hitoshi Hirata Tags: RESEARCH ARTICLE Source Type: research

Bone regeneration with hydroxyapatite particles loaded in photo ‐cross‐linkable hydrogel: An experimental study
This study explores the use of in situ cross-linked hyaluronic acid methacryloyl (HAMA) and hydroxyapatite particles (HAP) for bone defect repair. Human periodontal ligament stem cells (PDLSCs) were isolated and co-cultured with the HAMA-HAP composite. Osteogenic differentiation was evaluated using Alizarin Red staining, alkaline phosphatase activity quantification, and polymerase chain reaction (PCR). A cranial defect was induced in Sprague –Dawley rats. This defect was then filled with the HAMA-HAP composite and cross-linked using UV light exposure. Bone formation was assessed through radiographic and histological anal...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 5, 2024 Category: Materials Science Authors: Yu ‐si Li, Shan‐lin Guo, Julian Choi, Jia‐hao Zeng, Jing‐wen Zhang, Fang‐bing Zhao, Chun‐dong Liu, Xiao‐Qing Shen, Yuan‐Ming Geng Tags: RESEARCH ARTICLE Source Type: research

Robust aortic media adhesion using hydrophobically modified Alaska pollock gelatin ‐based adhesive for aortic dissections
In this study, we report innovative adhesives based on hydrophobically modified Alaska pollock gelatin (hm-ApGltn) with different alkyl or cholesteryl (Chol) groups that adhere to the media of the dissected aorta by combining hm-ApGltns with a biocompatible crosslinker, pentaerythritol poly(ethylene glycol) ether tetrasuccinimidyl glutarate. The modification of alkyl or Chol groups contributed to enhanced adhesion strength between porcine aortic media. The adhesion strength increased with increasing modification ratios of alkyl groups from propanoyl to dodecanoyl groups and then decreased at a modification ratio of ~20  ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 5, 2024 Category: Materials Science Authors: Temmei Ito, Ryo Mizuta, Shima Ito, Tetsushi Taguchi Tags: RESEARCH ARTICLE Source Type: research