Journal of Biomedical Materials Research Part B: Applied Biomaterials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

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(Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 13, 2022 Category: Materials Science Tags: ISSUE INFORMATION Source Type: research

Sterilization effects on poly(glycerol dodecanedioate): A biodegradable shape memory elastomer for biomedical applications
AbstractBiodegradable shape memory polymers provide unique regenerative medicine approaches in minimally invasive surgeries. Once heated, thermally responsive shape memory polymer devices can be compressed, programmed to fit within a small profile, delivered in the cold programmed state, and expanded when heated to body temperature. We have previously developed a biodegradable shape memory elastomer (SME), poly(glycerol dodecanedioate) (PGD), with transition temperatures near 37 °C exhibiting nonlinear elastic properties like numerous soft tissues. Using SMEs in the clinic requires disinfection and sterilization methods t...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 9, 2022 Category: Materials Science Authors: Harsha Ramaraju, Annabel M. McAtee, Ryan E. Akman, Adam S. Verga, Martin L. Bocks, Scott J. Hollister Tags: RESEARCH ARTICLE Source Type: research

Surface integrity modification of CoCrMo alloy by deep rolling in combination with sub ‐zero cooling as potential implant application
AbstractAlloys made of CoCrMo are well established as implants materials since decades in orthopedic surgery. The good mechanical properties, biocompatibility and especially the corrosion resistance are important rationales for the use of these alloys. Nevertheless, retrieved implants from revision surgery showed the occurrence of abrasion and corrosion. The wear mechanisms and the occurring corrosion processes might be reduced with a functionalization of the surface. The hexagonal phase of the cobalt chromium matrix plays an important role in the surface functionalization. It can be specifically transformed and set during...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 8, 2022 Category: Materials Science Authors: Joachim D öring, Stephan Basten, Martin Ecke, Maria Herbster, Benjamin Kirsch, Thorsten Halle, Christoph H. Lohmann, Jessica Bertrand, Jan Aurich Tags: RESEARCH ARTICLE Source Type: research

Dual ‐analgesic loaded UHMWPE exhibits synergistic antibacterial effects against Staphylococci
AbstractTotal joint arthroplasty is one of the most common surgeries in the United States, with almost a million procedures performed annually. Periprosthetic joint infections (PJI) remain the most devastating complications associated with total joint replacement. Effective antibacterial prophylaxis after primary arthroplasty could substantially reduce incidence rate of PJI. In the present study we propose to provide post-arthroplasty prophylaxis via dual-analgesic loaded ultra-high molecular weight polyethylene (UHMWPE). Our approach is based on previous studies that showed pronounced antibacterial activity of analgesic- ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 4, 2022 Category: Materials Science Authors: Dmitry Gil, Shannon Hugard, Nikolay Borodinov, Olga S. Ovchinnikova, Orhun K. Muratoglu, Hany Bedair, Ebru Oral Tags: RESEARCH ARTICLE Source Type: research

Nitric oxide releasing poly(vinyl alcohol)/S ‐nitrosated keratin film as a potential vascular graft
In this study, keratin-based NO donor of S-nitrosated keratin (KSNO) was blended with poly(vinyl alcohol) (PVA) and further crosslinked with sodium trimetaphosphate (STMP) to afford PVA/KSNO biocomposite films. These films could release NO sustainably for up to 10  days, resulting in the promotion of HUVECs growth and the inhibition of HUASMCs growth. In addition, these films displayed good blood compatibility and antibacterial activity. Taken together, these films have potential applications in vascular grafts. (Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials)
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 3, 2022 Category: Materials Science Authors: Xu Liu, Chenshu Wang, Mingyu Du, Jie Dou, Jinyu Yang, Jian Shen, Jiang Yuan Tags: RESEARCH ARTICLE Source Type: research

Gold –oxoborate nanocomposite‐coated orthodontic brackets gain antibacterial properties while remaining safe for eukaryotic cells
BOA (B —boron, O—oxygen, A—gold, Latinaurum) nanocomposite reduces the adhesion ofStreptococcus mutans to fixed orthodontic brackets by around 78% compared to noncoated appliances. Modified brackets remained safe for eukaryotic cells and meet ISO 10993-5:2009 requirements for medical devices. BOA coating is mechanically stable against brushing with a toothbrush, and its application is straightforward, effective, and ecologically friendly. AbstractThe study's main objective is to limit bacterial biofilm formation on fixed orthodontic appliances. Bacterial biofilm formation on such devices (e.g., brackets) causes ename...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 3, 2022 Category: Materials Science Authors: Jan Łyczek, Bartłomiej Bończak, Izabela Krzymińska, Konrad Giżyński, Jan Paczesny Tags: RESEARCH ARTICLE Source Type: research

The effect of strontium content on physicochemical and osteogenic property of Sr/Ag ‐containing TiO2 microporous coatings
AbstractStrontium (Sr) is the most common element introduced into TiO2 coatings to strengthen the osteogenic property of titanium implants. However, the optimal Sr content and its effect on osteogenic and physicochemical properties of the coatings need to be clarified. In the current study, TiO2 microporous coatings with different contents of Sr (9.64 –21.25 wt %) and silver (Ag) (0.38–0.75 wt %) were prepared via micro-arc oxidation technique. Sr contents did not change physicochemical properties of the coatings, including surface microstructure, micropore size and distribution, phase composition, roughness and hy...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 2, 2022 Category: Materials Science Authors: Yi ‐Rui Wang, Nuo‐Ya Yang, Hong Sun, Wei Dong, Jiu‐Peng Deng, Tian‐Xia Zheng, Meng‐Chun Qi Tags: RESEARCH ARTICLE Source Type: research

Agaricus blazei Murill extract ‐loaded in alginate/poly(vinyl alcohol) films prepared by Ca2+ cross‐linking for wound healing applications
AbstractThis work aimed the development and evaluation of the wound healing activity of films based on sodium alginate, polyvinyl alcohol (PVA) and Ca2+ loaded withAgaricus blazei Murill hydroalcoholic extract (AbE). Firstly, AbE was prepared using a previously standardized methodology. The films were prepared by casting technique and cross-linked with Ca2+ using CaCl2 as cross-linking agent. The physicochemical, morphological and water vapor barrier properties of the films were analyzed and the pre-clinical efficacy was investigated against the cutaneous wound model in mice. The films showed barrier properties to water va...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 1, 2022 Category: Materials Science Authors: Matheus da Silva Campelo, Lucas Barroso Mota, Jo ão Francisco Câmara Neto, Maria Lucianny Lima Barbosa, Maria Leônia da Costa Gonzaga, Luzia Kalyne Almeida Moreira Leal, Maria do Socorro Rocha Bastos, Sandra de Aguiar Soares, Nágila Maria Pont Tags: RESEARCH ARTICLE Source Type: research

Release of drugs used in the treatment of osteoporosis from zeolites with divalent ions —Influence of the type of ion and drug on the release profile
AbstractBisphosphonates are drugs that are used to treat osteoporosis that causes the low mineral density of the bones. These drugs can be delivered in several ways, but each method has disadvantages. Materials with high potential as carriers of these drugs are zeolites with divalent ions. The aim of this study was to investigate the effect of divalent cations (calcium, magnesium, zinc) and drug type (risedronate, zoledronate) on sorption and release of the drug for osteoporosis. It was proved that drug sorption occurs on all zeolites presented in this work. Risedronate sorption was highest in zinc zeolite and lowest in ca...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - December 1, 2022 Category: Materials Science Authors: Mariusz Sandomierski, Marcel Jakubowski, Maria Ratajczak, Monika Pokora, Monika Zieli ńska, Adam Voelkel Tags: RESEARCH ARTICLE Source Type: research

Effect of simulated body fluid formulation on orthopedic device apatite ‐forming ability assessment
AbstractIntegration of native bone into orthopedic devices is a key factor in long-term implant success. The material-tissue interface is generally accepted to consist of a hydroxyapatite layer so bioactive materials that can spontaneously generate this hydroxyapatite layer after implantation may improve patient outcomes. Per the ISO 22317:2014 standard, “Implants for surgery – In vitro evaluation for apatite-forming ability of implant materials,” bioactivity performance statements can be assessed by soaking the material in simulated body fluid (SBF) and evaluating the surface for the formation of a hydroxyapatite la...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - November 30, 2022 Category: Materials Science Authors: Alexander K. Nguyen, Sarah B. Nelson, Shelby A. Skoog, Panupong Jaipan, Peter E. Petrochenko, Aric Kaiser, Linh Lo, Jose Moreno, Roger J. Narayan, Peter L. Goering, Girish Kumar Tags: RESEARCH ARTICLE Source Type: research

3D ‐printed β‐TCP/S53P4 bioactive glass scaffolds coated with tea tree oil: Coating optimization, in vitro bioactivity and antibacterial properties
AbstractBone infection treatment is a significant challenge for the orthopedic field. 3D printing is a promising technology to produce scaffolds with customized architecture, able to stimulate and support bone growth. β-TCP and S53P4 bioactive glass (BG) are well-known biomaterials for scaffold manufacturing. However, a multifunctional scaffold, able to inhibit microbial proliferation at the defect site, is of increasing interest to avoid infection recurrence. Tea tree oil (TTO) has aroused interest as an antimi crobial agent to minimize the use of antibiotics. Therefore, combining the regenerative potential of a bioceram...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - November 29, 2022 Category: Materials Science Authors: Ana Paula Nogueira Alves, Marcela Arango ‐Ospina, Rodrigo Luiz Moraes Saldanha Oliveira, Igor Maia Ferreira, Elisângela Guzi Moraes, Malte Hartmann, Antônio Pedro Novaes Oliveira, Aldo Roberto Boccaccini, Eliandra Sousa Trichês Tags: RESEARCH ARTICLE Source Type: research

Resin cement coating reverts the machining damage on the flexural fatigue strength of lithium disilicate glass ‐ceramic
This study evaluated the effect of resin cement coating with high and low viscosities on the flexural fatigue strength of machined lithium disilicate glass-ceramic. Discs (IPS e.max CAD; Ivoclar Vivadent) were prepared and divided according to the surface condition (machining [M] —CEREC inLab; and polishing [P]—laboratory procedures), resin cement coating (with or without), and cement viscosity (high [H] and low [L]). The ceramic bonding surface was etched/primed by a one-step primer application followed by resin cement application (Variolink N base + high or low vis cosity catalyst; Ivoclar Vivadent). Biaxial flex...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - November 27, 2022 Category: Materials Science Authors: Michele Mirian May, Renan Vaz Machry, Sara Fraga, Guilherme Schmitt Andrade, Marco Antonio Bottino, Luiz Felipe Valandro, Liliana Gressler May Tags: RESEARCH ARTICLE Source Type: research

Antimicrobial activity and cytotoxicity study of cerium oxide nanoparticles with two different sizes
AbstractThe control over bacterial diseases requires the development of novel antibacterial agents. The use of antibacterial nanomedicines is one of the strategies to tackle antibiotic resistance. The study was designed to assess the antimicrobial activity of cerium oxide (CeO2) nanoparticles (NP) of two different sizes (CeO2 NP1 [1 –2 nm] and CeO2 NP2 [10 –12 nm]) and their cytotoxicity towards eukaryotic cells. The antimicrobial activity, effects of nanoparticles on DNA cleavage, microbial cell viability, and biofilm formation inhibition were analyzed. The impact of cerium oxide nanoparticles on eryptosis of eryt...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - November 25, 2022 Category: Materials Science Authors: Svetlana Yefimova, Vladimir Klochkov, Nataliya Kavok, Anton Tkachenko, Anatolii Onishchenko, Tatyana Chumachenko, Nadir Dizge, Sadin Özdemir, Serpil Gonca, Kasim Ocakoglu Tags: RESEARCH ARTICLE Source Type: research

Development of three ‐dimensionally printed vascular stents of bioresorbable poly(l‐lactide‐co‐caprolactone)
In this study, stents made from poly(l-lactic acid) (PLLA), poly( ε-caprolactone) (PCL) and poly(l-lactide-co-caprolactone) (PLCL) were manufactured by 3D printing and evaluated for radial strength, crystallinity and molecular weight. PLCL copolymerized by different proportions of lactic acid and caprolactone showed different mechanical and degradation properties. This demonstrated the potential of 3D printing as a low-cost and high throughput method for stent manufacturing. The PLLA and PLCL 95/5 stents had similar mechanical properties, whereas PLCL 85/15 and PCL stents both had relatively low radial strength. In genera...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - November 24, 2022 Category: Materials Science Authors: Justin Zhao, Ge Song, Qinghua Zhao, Hanqing Feng, Yunbing Wang, James M. Anderson, Hugh Zhao, Qing Liu Tags: RESEARCH ARTICLE Source Type: research

Human hair proteins as natural reactive oxygen species scavengers for in vitro applications
Solubilized hair proteins exhibit antioxidant properties due to their intrinsically high cysteine content. Human hair keratins (HHK) exhibit a superior radical scavenging capacity than Keratin assocaited proteins (KAPs). Incorporating HHK as media supplement yields efficient cyto-protection effect by quenching ROS levels against acute H2O2 exposure Maintenance of cytoprotective genes, HMOX1 and SOD2 were observed in human hair keratin-treated cells challenged with acute oxidation stress. AbstractHuman hair proteins are recognized for their intrinsically high cysteine content. They can be solubilized while preserving their ...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - November 24, 2022 Category: Materials Science Authors: Hui Ying Lai, Magdiel Inggrid Setyawati, Catarina Vizetto Duarte, Huei Min Chua, Choon Teck Low, Kee Woei Ng Tags: RESEARCH ARTICLE Source Type: research