Consumers' practices and safety perceptions regarding the use of materials for food preparation and storage: Analyses by age group
This study assesses the preferences, safety perceptions, and usage practices of Portuguese consumers regarding FCM used for cooking and food storage (cookware). An observational, quantitative, and transversal study was performed through an online survey created for this purpose, which involved 1179 Portuguese adults. Results were analyzed according to age. Safety was the factor considered most important when choosing cookware materials, although the choice criteria varied with age. The majority of respondents recognize the risk of food contamination through cookware. Stainless steel and glass were considered the safest mat...
Source: Food and Chemical Toxicology - June 17, 2023 Category: Food Science Authors: Joana Moura C íntia Ferreira-Pêgo Ana Sofia Fernandes Source Type: research

Letter to Editor "Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs": Important concerns on the validity of this article
Food Chem Toxicol. 2023 Jun 14:113897. doi: 10.1016/j.fct.2023.113897. Online ahead of print.NO ABSTRACTPMID:37328089 | PMC:PMC10265941 | DOI:10.1016/j.fct.2023.113897 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - June 16, 2023 Category: Food Science Authors: J érôme Barriere Fabrice Frank Lonni Besancon Alexander Samuel V éronique Saada Eric Billy Abraham Al-Ahmad Nans Florens Barbara Seitz-Polski Jacques Robert Source Type: research

Toxicogenomic analysis of physiologically important metals: An integrated in silico approach
In conclusion, exposure to essential metals might cause adverse effects via inflammation and oxidative stress.PMID:37328090 | DOI:10.1016/j.fct.2023.113895 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - June 16, 2023 Category: Food Science Authors: Satheeswaran Balasubramanian Vaishnavi Duraikannan Ekambaram Perumal Source Type: research

Letter to Editor "Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs": Important concerns on the validity of this article
Food Chem Toxicol. 2023 Jun 14:113897. doi: 10.1016/j.fct.2023.113897. Online ahead of print.NO ABSTRACTPMID:37328089 | DOI:10.1016/j.fct.2023.113897 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - June 16, 2023 Category: Food Science Authors: J érôme Barriere Fabrice Frank Lonni Besancon Alexander Samuel V éronique Saada Eric Billy Abraham Al-Ahmad Nans Florens Barbara Seitz-Polski Jacques Robert Source Type: research

Toxicogenomic analysis of physiologically important metals: An integrated in silico approach
In conclusion, exposure to essential metals might cause adverse effects via inflammation and oxidative stress.PMID:37328090 | DOI:10.1016/j.fct.2023.113895 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - June 16, 2023 Category: Food Science Authors: Satheeswaran Balasubramanian Vaishnavi Duraikannan Ekambaram Perumal Source Type: research

Ginsenoside Re blocks Bay k-8644-induced neurotoxicity via attenuating mitochondrial dysfunction and PKC δ activation in the hippocampus of mice: Involvement of antioxidant potential
Food Chem Toxicol. 2023 Jun 10:113869. doi: 10.1016/j.fct.2023.113869. Online ahead of print.ABSTRACTAlthough the anticonvulsant effects of ginsenosides are recognized, little is known about their effects on the convulsive behaviors induced by the activation of L-type Ca2+ channels. Here, we investigated whether ginsenoside Re (GRe) modulates excitotoxicity induced by the L-type Ca2+ channel activator Bay k-8644. GRe significantly attenuated Bay k-8644-induced convulsive behaviors and hippocampal oxidative stress in mice. GRe-mediated antioxidant potential was more pronounced in the mitochondrial fraction than cytosolic fr...
Source: Food and Chemical Toxicology - June 12, 2023 Category: Food Science Authors: Ngoc Kim Cuong Tran Ji Hoon Jeong Naveen Sharma Yen Nhi Doan Nguyen Hoang-Yen Phi Tran Duy-Khanh Dang Jung Hoon Park Jae Kyung Byun Dezhong Jin Zeng Xiaoyan Sung Kwon Ko Seung-Yeol Nah Hyoung-Chun Kim Eun-Joo Shin Source Type: research

Diagnostic potential of serum miR-532-3p as a circulating biomarker for experimental intrinsic drug-induced liver injury by acetaminophen and cisplatin in rats
Food Chem Toxicol. 2023 Jun 10;178:113890. doi: 10.1016/j.fct.2023.113890. Online ahead of print.ABSTRACTEvaluating tissue injury largely depends on serum biochemical analysis despite insufficient tissue specificity and low sensitivity. Therefore, attention has been paid to the potential of microRNAs (miRNAs) to overcome the limitations of the current diagnostic tools, as tissue-enriched miRNAs are detected in the blood upon tissue injury. First, using a cisplatin-injected rats, we screened a specific pattern of altered hepatic miRNAs and their target mRNAs. Subsequently, we identified novel liver-specific circulating miRN...
Source: Food and Chemical Toxicology - June 12, 2023 Category: Food Science Authors: Da-Bin Hwang Yoojin Seo Eunji Lee Dong-Hoon Won Changuk Kim MinHwa Kang Young Jeon Hyung-Sik Kim Jun Won Park Jun-Won Yun Source Type: research

Ginsenoside Re blocks Bay k-8644-induced neurotoxicity via attenuating mitochondrial dysfunction and PKC δ activation in the hippocampus of mice: Involvement of antioxidant potential
Food Chem Toxicol. 2023 Jun 10:113869. doi: 10.1016/j.fct.2023.113869. Online ahead of print.ABSTRACTAlthough the anticonvulsant effects of ginsenosides are recognized, little is known about their effects on the convulsive behaviors induced by the activation of L-type Ca2+ channels. Here, we investigated whether ginsenoside Re (GRe) modulates excitotoxicity induced by the L-type Ca2+ channel activator Bay k-8644. GRe significantly attenuated Bay k-8644-induced convulsive behaviors and hippocampal oxidative stress in mice. GRe-mediated antioxidant potential was more pronounced in the mitochondrial fraction than cytosolic fr...
Source: Food and Chemical Toxicology - June 12, 2023 Category: Food Science Authors: Ngoc Kim Cuong Tran Ji Hoon Jeong Naveen Sharma Yen Nhi Doan Nguyen Hoang-Yen Phi Tran Duy-Khanh Dang Jung Hoon Park Jae Kyung Byun Dezhong Jin Zeng Xiaoyan Sung Kwon Ko Seung-Yeol Nah Hyoung-Chun Kim Eun-Joo Shin Source Type: research

Diagnostic potential of serum miR-532-3p as a circulating biomarker for experimental intrinsic drug-induced liver injury by acetaminophen and cisplatin in rats
Food Chem Toxicol. 2023 Jun 10;178:113890. doi: 10.1016/j.fct.2023.113890. Online ahead of print.ABSTRACTEvaluating tissue injury largely depends on serum biochemical analysis despite insufficient tissue specificity and low sensitivity. Therefore, attention has been paid to the potential of microRNAs (miRNAs) to overcome the limitations of the current diagnostic tools, as tissue-enriched miRNAs are detected in the blood upon tissue injury. First, using a cisplatin-injected rats, we screened a specific pattern of altered hepatic miRNAs and their target mRNAs. Subsequently, we identified novel liver-specific circulating miRN...
Source: Food and Chemical Toxicology - June 12, 2023 Category: Food Science Authors: Da-Bin Hwang Yoojin Seo Eunji Lee Dong-Hoon Won Changuk Kim MinHwa Kang Young Jeon Hyung-Sik Kim Jun Won Park Jun-Won Yun Source Type: research

Ginsenoside Re blocks Bay k-8644-induced neurotoxicity via attenuating mitochondrial dysfunction and PKC δ activation in the hippocampus of mice: Involvement of antioxidant potential
Food Chem Toxicol. 2023 Jun 10:113869. doi: 10.1016/j.fct.2023.113869. Online ahead of print.ABSTRACTAlthough the anticonvulsant effects of ginsenosides are recognized, little is known about their effects on the convulsive behaviors induced by the activation of L-type Ca2+ channels. Here, we investigated whether ginsenoside Re (GRe) modulates excitotoxicity induced by the L-type Ca2+ channel activator Bay k-8644. GRe significantly attenuated Bay k-8644-induced convulsive behaviors and hippocampal oxidative stress in mice. GRe-mediated antioxidant potential was more pronounced in the mitochondrial fraction than cytosolic fr...
Source: Food and Chemical Toxicology - June 12, 2023 Category: Food Science Authors: Ngoc Kim Cuong Tran Ji Hoon Jeong Naveen Sharma Yen Nhi Doan Nguyen Hoang-Yen Phi Tran Duy-Khanh Dang Jung Hoon Park Jae Kyung Byun Dezhong Jin Zeng Xiaoyan Sung Kwon Ko Seung-Yeol Nah Hyoung-Chun Kim Eun-Joo Shin Source Type: research

Diagnostic potential of serum miR-532-3p as a circulating biomarker for experimental intrinsic drug-induced liver injury by acetaminophen and cisplatin in rats
Food Chem Toxicol. 2023 Jun 10:113890. doi: 10.1016/j.fct.2023.113890. Online ahead of print.ABSTRACTEvaluating tissue injury largely depends on serum biochemical analysis despite insufficient tissue specificity and low sensitivity. Therefore, attention has been paid to the potential of microRNAs (miRNAs) to overcome the limitations of the current diagnostic tools, as tissue-enriched miRNAs are detected in the blood upon tissue injury. First, using a cisplatin-injected rats, we screened a specific pattern of altered hepatic miRNAs and their target mRNAs. Subsequently, we identified novel liver-specific circulating miRNAs f...
Source: Food and Chemical Toxicology - June 12, 2023 Category: Food Science Authors: Da-Bin Hwang Yoojin Seo Eunji Lee Dong-Hoon Won Changuk Kim MinHwa Kang Young Jeon Hyung-Sik Kim Jun Won Park Jun-Won Yun Source Type: research

Ginsenoside Re blocks Bay k-8644-induced neurotoxicity via attenuating mitochondrial dysfunction and PKC δ activation in the hippocampus of mice: Involvement of antioxidant potential
Food Chem Toxicol. 2023 Jun 10:113869. doi: 10.1016/j.fct.2023.113869. Online ahead of print.ABSTRACTAlthough the anticonvulsant effects of ginsenosides are recognized, little is known about their effects on the convulsive behaviors induced by the activation of L-type Ca2+ channels. Here, we investigated whether ginsenoside Re (GRe) modulates excitotoxicity induced by the L-type Ca2+ channel activator Bay k-8644. GRe significantly attenuated Bay k-8644-induced convulsive behaviors and hippocampal oxidative stress in mice. GRe-mediated antioxidant potential was more pronounced in the mitochondrial fraction than cytosolic fr...
Source: Food and Chemical Toxicology - June 12, 2023 Category: Food Science Authors: Ngoc Kim Cuong Tran Ji Hoon Jeong Naveen Sharma Yen Nhi Doan Nguyen Hoang-Yen Phi Tran Duy-Khanh Dang Jung Hoon Park Jae Kyung Byun Dezhong Jin Zeng Xiaoyan Sung Kwon Ko Seung-Yeol Nah Hyoung-Chun Kim Eun-Joo Shin Source Type: research

Diagnostic potential of serum miR-532-3p as a circulating biomarker for experimental intrinsic drug-induced liver injury by acetaminophen and cisplatin in rats
Food Chem Toxicol. 2023 Jun 10:113890. doi: 10.1016/j.fct.2023.113890. Online ahead of print.ABSTRACTEvaluating tissue injury largely depends on serum biochemical analysis despite insufficient tissue specificity and low sensitivity. Therefore, attention has been paid to the potential of microRNAs (miRNAs) to overcome the limitations of the current diagnostic tools, as tissue-enriched miRNAs are detected in the blood upon tissue injury. First, using a cisplatin-injected rats, we screened a specific pattern of altered hepatic miRNAs and their target mRNAs. Subsequently, we identified novel liver-specific circulating miRNAs f...
Source: Food and Chemical Toxicology - June 12, 2023 Category: Food Science Authors: Da-Bin Hwang Yoojin Seo Eunji Lee Dong-Hoon Won Changuk Kim MinHwa Kang Young Jeon Hyung-Sik Kim Jun Won Park Jun-Won Yun Source Type: research

LncRNA OBFC2A modulated benzene metabolites-induced autophagy and apoptosis by interacting with LAMP2
In conclusion, we demonstrate that lncRNA OBFC2A mediates 1,4-BQ-induced apoptosis and autophagy by interacting with LAMP2. LncRNA OBFC2A could serve as a biomarker for hematotoxicity caused by benzene.PMID:37302536 | DOI:10.1016/j.fct.2023.113889 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - June 11, 2023 Category: Food Science Authors: Jingyu Wang Yujiao Chen Xiaoli Guo Wei Zhang Jing Ren Ai Gao Source Type: research

Estimation of the cumulative risks from dietary exposure to cadmium, arsenic, nickel, lead and chromium Guangzhou, China
This study provides substantial evidence for the non-negligible health risk in young children due to increased heavy metal exposure,at least on some toxicity targets.PMID:37302537 | DOI:10.1016/j.fct.2023.113887 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - June 11, 2023 Category: Food Science Authors: Florence Mhungu Yanfang Cheng Zhifeng Zhou Weiwei Zhang Yungang Liu Source Type: research