RIFM fragrance ingredient safety assessment, butyl 2-methylvalerate, CAS Registry Number 6297-41-2
Food Chem Toxicol. 2024 Apr 16;189 Suppl 1:114658. doi: 10.1016/j.fct.2024.114658. Online ahead of print.NO ABSTRACTPMID:38636596 | DOI:10.1016/j.fct.2024.114658 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - April 18, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Multi-elemental composition of botanical preparations and probabilistic evaluation of toxic metals and metalloids intake upon dietary exposure
Food Chem Toxicol. 2024 Apr 16;188:114664. doi: 10.1016/j.fct.2024.114664. Online ahead of print.ABSTRACTThe aim of this study was to evaluate the inorganic elemental composition (49 elements) of 29 botanical preparations obtained from fruits, leaves, peels, seeds, roots, fungi, and spirulina by using inductively coupled-mass spectrometry and a mercury analyzer. Simultaneously, the risk associated with the chronic dietary exposure to 12 toxic metals and metalloids among the European population was evaluated by using a probabilistic approach based on Monte Carlo simulations. The analysis revealed worrying intake levels of A...
Source: Food and Chemical Toxicology - April 18, 2024 Category: Food Science Authors: Maria Olga Varr à Lenka Hus áková Giovanni Tommaso Lanza Martina Piroutkov á Jan Pato čka Sergio Ghidini Emanuela Zanardi Source Type: research
Update to RIFM fragrance ingredient safety assessment, 2-methylhexanoic acid, CAS registry number 4536-23-6
Food Chem Toxicol. 2024 Apr 16;189 Suppl 1:114660. doi: 10.1016/j.fct.2024.114660. Online ahead of print.NO ABSTRACTPMID:38636598 | DOI:10.1016/j.fct.2024.114660 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - April 18, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Update to RIFM fragrance ingredient safety assessment, 2-methylheptanoic acid, CAS registry number 1188-02-9
Food Chem Toxicol. 2024 Apr 16;189 Suppl 1:114659. doi: 10.1016/j.fct.2024.114659. Online ahead of print.NO ABSTRACTPMID:38636599 | DOI:10.1016/j.fct.2024.114659 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - April 18, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Update to RIFM fragrance ingredient safety assessment, hexanoic acid, 4-methyl-, CAS Registry Number 1561-11-1
Food Chem Toxicol. 2024 Apr 16:114661. doi: 10.1016/j.fct.2024.114661. Online ahead of print.NO ABSTRACTPMID:38636594 | DOI:10.1016/j.fct.2024.114661 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - April 18, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Update to RIFM fragrance ingredient safety assessment, 4-ethyloctanoic acid, CAS Registry Number 16493-80-4
Food Chem Toxicol. 2024 Apr 16:114662. doi: 10.1016/j.fct.2024.114662. Online ahead of print.NO ABSTRACTPMID:38636595 | DOI:10.1016/j.fct.2024.114662 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - April 18, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
RIFM fragrance ingredient safety assessment, butyl 2-methylvalerate, CAS Registry Number 6297-41-2
Food Chem Toxicol. 2024 Apr 16:114658. doi: 10.1016/j.fct.2024.114658. Online ahead of print.NO ABSTRACTPMID:38636596 | DOI:10.1016/j.fct.2024.114658 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - April 18, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Multi-Elemental Composition of Botanical Preparations and Probabilistic Evaluation of Toxic Metals and Metalloids Intake Upon Dietary Exposure
Food Chem Toxicol. 2024 Apr 16:114664. doi: 10.1016/j.fct.2024.114664. Online ahead of print.ABSTRACTThe aim of this study was to evaluate the inorganic elemental composition (49 elements) of 29 botanical preparations obtained from fruits, leaves, peels, seeds, roots, fungi, and spirulina by using inductively coupled-mass spectrometry and a mercury analyzer. Simultaneously, the risk associated with the chronic dietary exposure to 12 toxic metals and metalloids among the European population was evaluated by using a probabilistic approach based on Monte Carlo simulations. The analysis revealed worrying intake levels of Al, A...
Source: Food and Chemical Toxicology - April 18, 2024 Category: Food Science Authors: Maria Olga Varr à Lenka Hus áková Giovanni Tommaso Lanza Martina Piroutkov á Jan Pato čka Sergio Ghidini Emanuela Zanardi Source Type: research
Update to RIFM fragrance ingredient safety assessment, 2-methylhexanoic acid, CAS Registry Number 4536-23-6
Food Chem Toxicol. 2024 Apr 16:114660. doi: 10.1016/j.fct.2024.114660. Online ahead of print.NO ABSTRACTPMID:38636598 | DOI:10.1016/j.fct.2024.114660 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - April 18, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Update to RIFM fragrance ingredient safety assessment, 2-methylheptanoic acid, CAS Registry Number 1188-02-9
Food Chem Toxicol. 2024 Apr 16:114659. doi: 10.1016/j.fct.2024.114659. Online ahead of print.NO ABSTRACTPMID:38636599 | DOI:10.1016/j.fct.2024.114659 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - April 18, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
In vitro and in vivo exposure of endothelial cells to dibutyl phthalate promotes monocyte adhesion
Food Chem Toxicol. 2024 Apr 15;188:114663. doi: 10.1016/j.fct.2024.114663. Online ahead of print.ABSTRACTThe effect of endothelial cells' exposure to dibutyl phthalate (DBP) on monocyte adhesion is largely unknown. We evaluated monocyte adhesion to DBP-exposed endothelial cells by combining three approaches: short-term exposure (24 h) of EA.hy926 cells to 10-6, 10-5, and 10-4 M DBP, long-term exposure (12 weeks) of EA.hy926 cells to 10-9, 10-8, and 10-7 M DBP, and exposure of rats (28 and 90 days) to 100, 500, and 5000 mg DBP/kg food. Monocyte adhesion to human EA.hy926 and rat aortic endothelial cells, expression of selec...
Source: Food and Chemical Toxicology - April 17, 2024 Category: Food Science Authors: Dunja Kokai Jelena Markovic Filipovic Marija Opacic Ivana Ivelja Vojislav Banjac Bojana Stanic Nebojsa Andric Source Type: research
RIFM fragrance ingredient safety assessment, N,N-diethyloctamide, CAS Registry Number 996-97-4
Food Chem Toxicol. 2024 Apr 15:114657. doi: 10.1016/j.fct.2024.114657. Online ahead of print.NO ABSTRACTPMID:38631436 | DOI:10.1016/j.fct.2024.114657 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - April 17, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Neurotoxicity of dibutyl phthalate in zebrafish larvae: Decreased energy acquisition by neurons
In conclusion, DBP-induced neurotoxicity may be the combined result of insufficient neuronal energy acquisition, damage to mitochondrial structure, apoptosis and autophagy. These results provide a theoretical basis for understanding the neurotoxic effects of DBP.PMID:38621509 | DOI:10.1016/j.fct.2024.114666 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - April 15, 2024 Category: Food Science Authors: Yue Tao Xiaodong Yi Yanyan Gu Rongyi Yang Zixu Li Xiangyong Guo Donglin Zhao Ying Zhang Source Type: research
Neurotoxicity of dibutyl phthalate in zebrafish larvae: Decreased energy acquisition by neurons
In conclusion, DBP-induced neurotoxicity may be the combined result of insufficient neuronal energy acquisition, damage to mitochondrial structure, apoptosis and autophagy. These results provide a theoretical basis for understanding the neurotoxic effects of DBP.PMID:38621509 | DOI:10.1016/j.fct.2024.114666 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - April 15, 2024 Category: Food Science Authors: Yue Tao Xiaodong Yi Yanyan Gu Rongyi Yang Zixu Li Xiangyong Guo Donglin Zhao Ying Zhang Source Type: research
Public views of animal testing and alternatives in chemical risk assessment
This study aimed at investigating public views of animal testing and potential alternatives, namely in vitro and in silico testing. An online survey was conducted (N = 965). The results suggest that people make trade-offs, as they experience negative affect regarding in vivo testing, which partly might explain their openness regarding certain alternatives. In vitro tests were attributed the highest ability to determine harmful effects of chemicals for different endpoints, followed by in vivo and in silico tests. Our results further showed that many people accept chemicals to be only tested with alternatives, with highest a...
Source: Food and Chemical Toxicology - April 14, 2024 Category: Food Science Authors: Angela Bearth Lisa Wiesner Michael Siegrist Source Type: research
