RIFM fragrance ingredient safety assessment, 3-(p-isopropylphenyl)propionaldehyde, CAS registry number 7775-00-0
Food Chem Toxicol. 2024 Mar 13;183 Suppl 1:114555. doi: 10.1016/j.fct.2024.114555. Online ahead of print.NO ABSTRACTPMID:38484489 | DOI:10.1016/j.fct.2024.114555 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - March 14, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Update to RIFM fragrance ingredient safety assessment, p-tolyl alcohol, CAS Registry Number 589-18-4
Food Chem Toxicol. 2024 Mar 12:114575. doi: 10.1016/j.fct.2024.114575. Online ahead of print.NO ABSTRACTPMID:38485040 | DOI:10.1016/j.fct.2024.114575 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - March 14, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Update to RIFM fragrance ingredient safety assessment, 4-methylpentanoic acid, CAS Registry Number 646-07-1
Food Chem Toxicol. 2024 Mar 12:114573. doi: 10.1016/j.fct.2024.114573. Online ahead of print.NO ABSTRACTPMID:38485041 | DOI:10.1016/j.fct.2024.114573 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - March 14, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Unveiling the mechanisms of trichloroethylene hypersensitivity syndrome: Exploring the role of connexin 43 gap junctions in severe skin damage
This study aims to elucidate the mechanism underlying skin damage from the perspective of intercellular communication and gap junctions in THS. Our results verified that hyperactivation of connexin43 gap junctions, caused by the aberrantly elevated expression of connexin43, triggers a bystander effect that promotes apoptosis and inflammation in THS via the TNF-TNFRSF1B and mitochondria-associated pathways. Additionally, we identified the gap junction inhibitor Carbenoxolone disodium (CBX) as a promising agent for the treatment of skin damage in THS. CBX protects against inflammatory cell infiltration in the skin and decrea...
Source: Food and Chemical Toxicology - March 14, 2024 Category: Food Science Authors: Bo Jiao Haiqin Jiang Shuai Liu Yican Wang Yuanyuan Chen Huawei Duan Yong Niu Meili Shen Hongsheng Wang Yufei Dai Source Type: research
RIFM fragrance ingredient safety assessment, 3-(p-isopropylphenyl)propionaldehyde, CAS registry number 7775-00-0
Food Chem Toxicol. 2024 Mar 13;183 Suppl 1:114555. doi: 10.1016/j.fct.2024.114555. Online ahead of print.NO ABSTRACTPMID:38484489 | DOI:10.1016/j.fct.2024.114555 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - March 14, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Update to RIFM fragrance ingredient safety assessment, p-tolyl alcohol, CAS Registry Number 589-18-4
Food Chem Toxicol. 2024 Mar 12:114575. doi: 10.1016/j.fct.2024.114575. Online ahead of print.NO ABSTRACTPMID:38485040 | DOI:10.1016/j.fct.2024.114575 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - March 14, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Update to RIFM fragrance ingredient safety assessment, 4-methylpentanoic acid, CAS Registry Number 646-07-1
Food Chem Toxicol. 2024 Mar 12:114573. doi: 10.1016/j.fct.2024.114573. Online ahead of print.NO ABSTRACTPMID:38485041 | DOI:10.1016/j.fct.2024.114573 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - March 14, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Unveiling the mechanisms of trichloroethylene hypersensitivity syndrome: Exploring the role of connexin 43 gap junctions in severe skin damage
This study aims to elucidate the mechanism underlying skin damage from the perspective of intercellular communication and gap junctions in THS. Our results verified that hyperactivation of connexin43 gap junctions, caused by the aberrantly elevated expression of connexin43, triggers a bystander effect that promotes apoptosis and inflammation in THS via the TNF-TNFRSF1B and mitochondria-associated pathways. Additionally, we identified the gap junction inhibitor Carbenoxolone disodium (CBX) as a promising agent for the treatment of skin damage in THS. CBX protects against inflammatory cell infiltration in the skin and decrea...
Source: Food and Chemical Toxicology - March 14, 2024 Category: Food Science Authors: Bo Jiao Haiqin Jiang Shuai Liu Yican Wang Yuanyuan Chen Huawei Duan Yong Niu Meili Shen Hongsheng Wang Yufei Dai Source Type: research
Trace metals translocation from soil to plants: Health risk assessment via consumption of vegetables in the urban sprawl of a developing country
Food Chem Toxicol. 2024 Mar 9:114580. doi: 10.1016/j.fct.2024.114580. Online ahead of print.ABSTRACTThe study was conducted at 15 locations around the thermal power plant of Patuakhali district at the coastal area of Bangladesh to determine trace elements in vegetable and assess risk of toxicity. Eight vegetables, namely, tomato (Solanum lycopersicum L.), radish (Raphanus raphanistrum L.), bean (Phaseolus vulgaris L.), brinjal (Solanum melongena L.), bottle gourd (Lagenaria siceraria L.), red amaranth (Amaranthus cruentus L.), arum (Arum maculatum L.) and lady's finger (Abelmoschus esculentus L.) were analyzed for nine tra...
Source: Food and Chemical Toxicology - March 11, 2024 Category: Food Science Authors: Km Shamsul Haque Md Saiful Islam Sujat Ahmed Md Zillur Rahman Debolina Halder Hemy Md Towhidul Islam Md Kamal Hossain Md Rafiq Uddin Abu Reza Md Towfiqul Islam Md Yousuf Mia Zulhilmi Ismail Abdullah Al Bakky Khalid A Ibrahim Abubakr M Idris Source Type: research
RIFM fragrance ingredient safety assessment, cyclohexanol, 2-methoxy-4-propyl-, CAS Registry Number 23950-98-3
Food Chem Toxicol. 2024 Mar 9:114566. doi: 10.1016/j.fct.2024.114566. Online ahead of print.NO ABSTRACTPMID:38467294 | DOI:10.1016/j.fct.2024.114566 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - March 11, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Update to RIFM fragrance ingredient safety assessment, ethyl 10-undecenoate, CAS Registry Number 692-86-4
Food Chem Toxicol. 2024 Mar 9:114567. doi: 10.1016/j.fct.2024.114567. Online ahead of print.NO ABSTRACTPMID:38467295 | DOI:10.1016/j.fct.2024.114567 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - March 11, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
RIFM fragrance ingredient safety assessment, 5-ethyl-2,3,4,5-tetramethylcyclohexen-1-one, CAS Registry Number 17369-60-7
Food Chem Toxicol. 2024 Mar 9:114569. doi: 10.1016/j.fct.2024.114569. Online ahead of print.NO ABSTRACTPMID:38467296 | DOI:10.1016/j.fct.2024.114569 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - March 11, 2024 Category: Food Science Authors: A M Api A Bartlett D Belsito D Botelho M Bruze A Bryant-Freidrich G A Burton M A Cancellieri H Chon M L Dagli W Dekant C Deodhar K Farrell A D Fryer L Jones K Joshi A Lapczynski M Lavelle I Lee H Moustakas J Muldoon T M Penning G Ritacco N Sadekar I Schem Source Type: research
Trace elements in commercially available infant formulas in Iran: Determination and estimation of health risks
The objective of the present study was to ascertain the concentrations of some trace elements namely; arsenic, cadmium, chromium, copper, nickel and lead in infant formulas sold in Iran and to estimate the potential health risks to the infants through consumption of these products. The mean concentrations of As, Cd, Cr, Cu, Ni and Pb in infant formula samples were 0.006, 0.040, 0.3980, 2.014, 0.166 and 0.285 mg/kg, respectively. The mean levels of the trace elements were in the following order: Cu > Cr > Pb > Ni > Cd > As. For arsenic, cadmium and copper, calculated EWIs (estimated weekly intakes) were withi...
Source: Food and Chemical Toxicology - March 11, 2024 Category: Food Science Authors: Roya Peirovi-Minaee Mahmoud Taghavi Marzieh Harimi Ahmad Zarei Source Type: research
Occurrence and health risk assessment of tropane alkaloids in cereal foods consumed in Korea
This study aimed to determine the occurrence of TA in cereal foods and assess the potential health risks associated with their consumption in Korea. TA levels were analyzed in 80 raw and 71 processed cereal samples, which were distributed throughout Korea in 2021, using ultra-performance liquid chromatography-tandem mass spectrometry. At least one of the six TA species, namely atropine, scopolamine, pseudotropine, tropinone, scopine, and 6-hydroxytropinone, was detected in 10 out of the 151 samples at levels ranging from 0.12 to 88.10 μg kg-1. Dietary exposure (mean, 0.23 ng kg-1 bw day-1) to atropine and scopolamine in t...
Source: Food and Chemical Toxicology - March 11, 2024 Category: Food Science Authors: Songyi Han Sukyeong Jang Sujin Oh Jian Lee Hwa-Jeong Lee Yong Eui Koo Byung Hee Kim Source Type: research
RIFM fragrance ingredient safety assessment, dihydromyrcenol, CAS registry number 18479-58-8
Food Chem Toxicol. 2024 Mar 9:114572. doi: 10.1016/j.fct.2024.114572. Online ahead of print.NO ABSTRACTPMID:38467299 | DOI:10.1016/j.fct.2024.114572 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - March 11, 2024 Category: Food Science Authors: A M Api D Belsito D Botelho M Bruze G A Burton M A Cancellieri H Chon M L Dagli M Date W Dekant C Deodhar A D Fryer L Jones K Joshi M Kumar A Lapczynski M Lavelle I Lee D C Liebler H Moustakas M Na T M Penning G Ritacco J Romine N Sadekar T W Schultz D Se Source Type: research
