Sub-chronic oral toxicity of a water-soluble extract of Centella asiatica (Centell-S) in Wistar rats

CONCLUSIONS: Under the specific conditions of the OECD GLP 408, Repeated Dose 90-day Oral Toxicity Study in Rodents, the no observed adverse effect level (NOAEL) of Centell-S was 800 mg/kg/day. These findings are promising for the continued development of Centell-S as a phytopharmaceutical for clinical applications.PMID:38336016 | DOI:10.1016/j.fct.2024.114509

Source: Food and Chemical Toxicology - February 9, 2024 Category: Food Science Authors: Thammaporn Junsai Supawit Tangpanithandee Passaraporn Srimangkornkaew Kran Suknuntha Pornpun Vivithanaporn Phisit Khemawoot Source Type: research