Intensity-Modulated Radiation Therapy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Dosimetric parameters predict radiation-induced temporal lobe necrosis in nasopharyngeal carcinoma patients: A systematic review and meta-analysis
In conclusion, this systematic review highlights the significance of dosimetric parameters, particularly Dmax and D1cc, in predicting TLN risk in NPC patients undergoing 3D-CRT, IMRT, and VMAT. The findings provide valuable insights that can help in developing optimal treatment planning strategies and contribute to the development of clinical guidelines in this field.PMID:38537680 | DOI:10.1016/j.radonc.2024.110258 (Source: Ann Oncol)
Source: Ann Oncol - March 27, 2024 Category: Cancer & Oncology Authors: Jun Dong Wai Tong Ng Charlene H L Wong Ji-Shi Li Heleen Bollen James C H Chow Avraham Eisbruch Anne W M Lee Victor H F Lee Sweet Ping Ng Sandra Nuyts Robert Smee Alfio Ferlito Source Type: research

Dosimetric parameters predict radiation-induced temporal lobe necrosis in nasopharyngeal carcinoma patients: A systematic review and meta-analysis
In conclusion, this systematic review highlights the significance of dosimetric parameters, particularly Dmax and D1cc, in predicting TLN risk in NPC patients undergoing 3D-CRT, IMRT, and VMAT. The findings provide valuable insights that can help in developing optimal treatment planning strategies and contribute to the development of clinical guidelines in this field.PMID:38537680 | DOI:10.1016/j.radonc.2024.110258 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 27, 2024 Category: Radiology Authors: Jun Dong Wai Tong Ng Charlene H L Wong Ji-Shi Li Heleen Bollen James C H Chow Avraham Eisbruch Anne W M Lee Victor H F Lee Sweet Ping Ng Sandra Nuyts Robert Smee Alfio Ferlito Source Type: research

Correction: Evolution of radiation-induced temporal lobe injury after intensity-modulated radiation therapy in nasopharyngeal carcinoma: a large cohort retrospective study
(Source: Radiation Oncology)
Source: Radiation Oncology - March 27, 2024 Category: Cancer & Oncology Authors: Jing Hou, Yun He, Handong Li, Zhaodong Ai, Qiang Lu, Biao Zeng, Chuanmiao Xie and Xiaoping Yu Tags: Correction Source Type: research

Hypofractionated whole breast IMRT with HDR brachytherapy boost in early-stage breast cancer: Long-term results from a single-center
The addition of a boost to the lumpectomy bed after whole-breast (WB) radiotherapy plays a key role in the treatment of patients with breast cancer (BC). The clinical benefits of a boost with high-dose-rate brachytherapy (HDR-BT) after conventional fractionation is supported by a large body of evidence. However, few studies have described its outcomes after a hypofractionated scheme. (Source: Brachytherapy)
Source: Brachytherapy - March 23, 2024 Category: Cancer & Oncology Authors: Ana Aurora D íaz-Gavela, Elia del Cerro Peñalver, Sofía Sanchez-Garcia, Eduardo Pardo-Perez, Israel John Thuissard-Vasallo, Cristina Andreu-Vázquez, María Yolanda Molina López, Marina Pena Huertas, Luis Leonardo Guerrero-Gómez, David Sanz-Rosa, Fel Tags: Original Research Source Type: research

Long-term survival, toxicities, and the role of chrono-chemotherapy with different infusion rates in locally advanced nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy: a retrospective study with a 5-year follow-up
ConclusionLong-term analysis confirmed that in CCRT, cisplatin administration with sinusoidal chrono-modulated infusion was not superior to the constant infusion rate in terms of long-term toxicity and prognosis. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - March 22, 2024 Category: Cancer & Oncology Source Type: research

MR-guided stereotactic radiation therapy for head and neck cancers
CONCLUSION: The use of Monaco treatment planning and online adaptation can achieve dosimetric results comparable to VMAT plans, with the additional benefits of real-time tracking of target volume and nearby critical structures. This offers the potential to treat aggressive and variable tumors in HN SBRT and improve local control and treatment toxicity.PMID:38510980 | PMC:PMC10950743 | DOI:10.1016/j.ctro.2024.100760 (Source: Cancer Control)
Source: Cancer Control - March 21, 2024 Category: Cancer & Oncology Authors: He Wang Jinzhong Yang Anna Lee Jack Phan Tze Yee Lim Clifton D Fuller Eun Young Han Dong Joo Rhee Travis Salzillo Yao Zhao Nitish Chopra Mary Pham Pam Castillo Angela Sobremonte Amy C Moreno Jay P Reddy David Rosenthal Adam S Garden Xin Wang Source Type: research

Updated Analysis of Comparative Toxicity of Proton and Photon Radiation for Prostate Cancer
CONCLUSION: In this observational study, there were no statistically significant differences between PBT and IMRT in terms of GI or GU toxicity.PMID:38507655 | DOI:10.1200/JCO.23.01604 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - March 20, 2024 Category: Cancer & Oncology Authors: James B Yu David M DeStephano Brian Jeffers David P Horowitz Pamela R Soulos Cary P Gross Simon K Cheng Source Type: research

Automatic IMRT treatment planning through fluence prediction and plan fine-tuning for nasopharyngeal carcinoma
At present, the implementation of intensity-modulated radiation therapy (IMRT) treatment planning for geometrically complex nasopharyngeal carcinoma (NPC) through manual trial-and-error fashion presents challe... (Source: Radiation Oncology)
Source: Radiation Oncology - March 20, 2024 Category: Cancer & Oncology Authors: Wenwen Cai, Shouliang Ding, Huali Li, Xuanru Zhou, Wen Dou, Linghong Zhou, Ting Song and Yongbao Li Tags: Research Source Type: research

Cancers, Vol. 16, Pages 1192: Comprehensive 3DCRT Hypofractionated Radiotherapy Schedule for Localized Prostate Adenocarcinoma in the Era of IMRT: Dosimetric and Endoscopic Analysis
Conclusions: A thorough delineation of the rectal wall and its subsegments, together with the dosimetric analysis of these structures, may reduce late rectal toxicity. Dosimetric parameters such as V52.17Gy and V56.52Gy were identified to have a significant impact on rectal mucosal injury; additional dose endpoint validation and its relation to late GI toxicity is needed. (Source: Cancers)
Source: Cancers - March 18, 2024 Category: Cancer & Oncology Authors: Andromachi Kougioumtzopoulou Nick Syrigos Anna Zygogianni Ioannis Georgakopoulos Kalliopi Platoni George Patatoukas Kimon Tzannis Aristotelis Bamias Nikolaos Kelekis Vasileios Kouloulias Tags: Article Source Type: research

Reducing Salivary Toxicity with Adaptive Radiotherapy (ReSTART): A Randomized Controlled Trial comparing conventional IMRT to adaptive IMRT in head and neck Squamous Cell Carcinomas
The utility of Adaptive Radiotherapy (ART) in Head and Neck Squamous Cell Carcinoma (HNSCC) remains to be ascertained. While multiple retrospective and single-arm prospective studies have demonstrated its efficacy in decreasing parotid doses and reducing xerostomia, there is a lack of adequate randomized evidence. (Source: Clinical Oncology)
Source: Clinical Oncology - March 18, 2024 Category: Radiology Authors: Sarbani Ghosh-Laskar, Shwetabh Sinha, Anuj Kumar, Asesh Samanta, Samarpita Mohanty, Srikant Kale, Faizalam Khan, Shirley Lewis Salins, Vedang Murthy Tags: Original Article Source Type: research

Error detection using a multi-channel hybrid network with a low-resolution detector in patient-specific quality assurance
CONCLUSION: The proposed multi-channel hybrid network exhibits a high level of accuracy in identifying MLC errors using low-resolution detectors. The method offers an effective and reliable solution for promoting quality and safety of IMRT QA.PMID:38488663 | DOI:10.1002/acm2.14327 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - March 15, 2024 Category: Physics Authors: Bing Yan Jun Shi Xudong Xue Hu Peng Aidong Wu Xiao Wang Chi Ma Source Type: research

Error detection using a multi-channel hybrid network with a low-resolution detector in patient-specific quality assurance
CONCLUSION: The proposed multi-channel hybrid network exhibits a high level of accuracy in identifying MLC errors using low-resolution detectors. The method offers an effective and reliable solution for promoting quality and safety of IMRT QA.PMID:38488663 | DOI:10.1002/acm2.14327 (Source: Cancer Control)
Source: Cancer Control - March 15, 2024 Category: Cancer & Oncology Authors: Bing Yan Jun Shi Xudong Xue Hu Peng Aidong Wu Xiao Wang Chi Ma Source Type: research

Arytenoid-Sparing Intensity-Modulated Radiotherapy for Early-Stage Glottic Cancer
In this study, we demonstrate initial dosimetric results of a novel approach called arytenoid-sparing IMRT (AS-IMRT), which is aimed at reducing speech and swallowing toxicity. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 14, 2024 Category: Radiology Authors: A. Rybkin, J. Scott, M.R. Young, H.S.M. Park Tags: 129 Source Type: research