Intensity-Modulated Radiation Therapy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A novel AP/PA total body irradiation technique using abutting IMRT fields at extended SSD
CONCLUSIONS: We have developed a promising TBI technique using abutting IMRT fields at extended SSD. The patient is in a comfortable recumbent position with good reproducibility and less motion during treatment. An additional benefit of this technique is that full 3D dose distribution is available from the TPS with a DVH summary for organs of interest. The technique allows precise sparing of lungs and kidneys and can be executed in any linac room.PMID:38425126 | DOI:10.1002/acm2.14213 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - March 1, 2024 Category: Physics Authors: Xiaomin Liang Peixiong Li Qiuwen Wu Source Type: research

Organ-sparing techniques and dose-volume constrains used in breast cancer radiation therapy - Results from European and Latin American surveys
CONCLUSION: The delineation approaches and sparing techniques for OAR in BC RT vary between ROs worldwide. The low response rate to the dose constraints subset of queries reflects the uncertainty surrounding this topic and supports the need for detailed consensus recommendations in the clinical practice.PMID:38425691 | PMC:PMC10900109 | DOI:10.1016/j.ctro.2024.100752 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - March 1, 2024 Category: Cancer & Oncology Authors: Monica-Emila Chiril ă Fatjona Kraja Gustavo Nader Marta Wellington Furtado Pimenta Neves Junior Gustavo Viani de Arruda Andr é Guimarães Gouveia Pierfrancesco Franco Philip Poortmans Ivica Ratosa Source Type: research

Organ-sparing techniques and dose-volume constrains used in breast cancer radiation therapy - Results from European and Latin American surveys
CONCLUSION: The delineation approaches and sparing techniques for OAR in BC RT vary between ROs worldwide. The low response rate to the dose constraints subset of queries reflects the uncertainty surrounding this topic and supports the need for detailed consensus recommendations in the clinical practice.PMID:38425691 | PMC:PMC10900109 | DOI:10.1016/j.ctro.2024.100752 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - March 1, 2024 Category: Cancer & Oncology Authors: Monica-Emila Chiril ă Fatjona Kraja Gustavo Nader Marta Wellington Furtado Pimenta Neves Junior Gustavo Viani de Arruda Andr é Guimarães Gouveia Pierfrancesco Franco Philip Poortmans Ivica Ratosa Source Type: research

Technical note: A simple method for patient-specific quality assurance for lateral targets on a 1.5 T MR-Linac
J Appl Clin Med Phys. 2024 Mar 1:e14323. doi: 10.1002/acm2.14323. Online ahead of print.ABSTRACTThe Elekta Unity magnetic resonance (MR) linac is limited to longitudinal couch motion and a sagittal-only laser, which restricts the ability to perform patient-specific quality assurance (PSQA) intensity-modulated radiotherapy (IMRT) measurements for very lateral targets. This work introduces a simple method to perform PSQA using the Sun Nuclear ArcCheck-MR phantom at left and right lateral positions without additional equipment or in-house construction. The proposed setup places the center of the phantom 1.3 cm vertical and 12...
Source: Journal of Applied Clinical Medical Physics - March 1, 2024 Category: Physics Authors: William S Ferris Blake R Smith Daniel E Hyer Joel J St-Aubin Source Type: research

The use of dose surface maps as a tool to investigate spatial dose delivery accuracy for the rectum during prostate radiotherapy
CONCLUSION: DSMs enabled spatial investigations of planned and delivered doses can uncover associations with interfraction motion that are otherwise masked in DVHs. Investigations of dose delivery accuracy in radiotherapy may benefit from using DSMs over DVHs for certain organs such as the rectum.PMID:38425148 | DOI:10.1002/acm2.14314 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - March 1, 2024 Category: Physics Authors: Haley M Patrick John Kildea Source Type: research

Whole-pelvic irradiation with boost to involved nodes and prostate in node-positive prostate cancer —long-term data from the prospective PLATIN-2 trial
ConclusionDefinitive radiation to the lymphatic drainage with SIB to the involved nodes and prostate is a safe and effective treatment approach for patients with treatment-naïve, node-positive prostate cancer with excellent infield tumor control rates and tolerable toxicity. Location rather than number of involved nodes is a major risk factor for progression. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - March 1, 2024 Category: Cancer & Oncology Source Type: research

Noninvasive inter- and intrafractional motion control in ultrahypofractionated radiation therapy of prostate cancer using RayPilot HypoCath ™—a substitute for gold fiducial-based IGRT?
Conclusionthe HypoCath system allows highly accurate and robust intrafractional motion monitoring. In conjunction with cone beam CT (CBCT) for initial patient setup, it could be used as a standalone image-guided radiation therapy (IGRT) system. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - March 1, 2024 Category: Cancer & Oncology Source Type: research

Capecitabine/cisplatin combined with concurrent intensity-modulated radiation therapy: a feasible therapeutic strategy for anal squamous cell carcinoma
ConclusionThe XP regimen was as effective as the MF regimen in non-metastatic ASCC. Compared with the standard MF regimen, XP combined with IMRT showed higher treatment completion and lower toxicities. It could be considered a feasible alternative for patients with non-metastatic ASCC. (Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - March 1, 2024 Category: Cancer & Oncology Source Type: research

Impact of prostate position-based image-guidance in intensity-modulated radiation therapy for localized prostate cancer
ConclusionsThe use of P-IGRT with higher doses and smaller margins was correlated with significantly better biochemical control, and a lower incidence of rectal bleeding in IMRT for intermediate-risk prostate cancer. The enhanced accuracy using P-IGRT has the potential to independently improve disease control and reduce late rectal bleeding. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - March 1, 2024 Category: Cancer & Oncology Source Type: research

Biochemical outcome after curative treatment for localized prostate cancer with external beam radiotherapy: a cross-sectional study
This study retrospectively assessed the clinicopathological characteristics and biochemical outcomes of patients treated for localised CaP with external beam radiotherapy (EBRT) between 2015 and 2020 at a major cancer treatment centre in Accra, Ghana. Patients' socio-demographic and clinical data were collected from their hospital records and analysed with the Statistical Package for Social Sciences version 26. Biochemical failure (BCF) was defined as an increase in the level of serum prostate-specific antigen (PSA) >2 ng/mL above the nadir after curative therapy based on the Phoenix definition. The mean age was 67.6 ye...
Source: Ecancermedicalscience - February 28, 2024 Category: Cancer & Oncology Authors: Joseph Daniels Kofi Adesi Kyei Kikelomo Adeola Badejoko-Okunade Samuel Anim-Sampong Samuel Nii Adu Tagoe William Kwadwo Antwi Joana Ainuson-Quampah Adewumi Alabi Anthonia Sowunmi Judith Naa Odey Tackie Source Type: research

Introducing a new approach for calibrating radiotherapy room lasers without using external laser source or dedicated phantoms
ConclusionOur new approach for laser alignment was performed and evaluated successfully. This method can provided a more accurate procedure than the conventional method without needing an external laser source or dedicated laser alignment phantom. (Source: Health and Technology)
Source: Health and Technology - February 28, 2024 Category: Information Technology Source Type: research

Quality of Life Longitudinal Evaluation in Prostate Cancer Patients from Radiotherapy Start to 5 Years after IMRT-IGRT
CONCLUSIONS: In this prospective, longitudinal, observational study, high radiation IMRT doses delivered for PCa led to a temporary worsening of QoL, which tended to be completely resolved at six months. Such transient worsening was mostly associated with acute GI/GU toxicity, WPRT, and higher prescription doses.PMID:38392056 | DOI:10.3390/curroncol31020062 (Source: Current Oncology)
Source: Current Oncology - February 23, 2024 Category: Cancer & Oncology Authors: Angelo Maggio Tiziana Rancati Marco Gatti Domenico Cante Barbara Avuzzi Cinzia Bianconi Fabio Badenchini Bruno Farina Paolo Ferrari Tommaso Giandini Giuseppe Girelli Valeria Landoni Alessandro Magli Eugenia Moretti Edoardo Petrucci Paolo Salmoiraghi Giuse Source Type: research