Large Institutional Experience of Early Outcomes and Dosimetric Findings with Postoperative Stereotactic Partial Breast Irradiation in Breast Cancer
Accelerated partial breast irradiation (APBI) has been shown to be effective in carefully selected patients, based on evidence from at least 8 prospective randomized trials enrolling over 10,000 women[1,2]. A variety of APBI techniques have been investigated, with external beam techniques such as 3-dimensional conformal radiation therapy and intensity-modulated radiation therapy (IMRT) being favored due to their noninvasiveness and operator independence[3]. A recent meta-analysis showed that APBI was associated with significantly lower rate of acute adverse events compared to whole breast irradiation (WBI), with no differe...
Source: Radiotherapy and Oncology - December 21, 2023 Category: Radiology Authors: Jee Suk Chang, Jeongshim Lee, Frank A. Vicini, Jin Sung Kim, Jihun Kim, Seo Hee Choi, Ik Jae Lee, Yong Bae Kim Tags: Original Article Source Type: research

Dosimetric comparison between intensity-modulated radiation therapy and volumetric-modulated arc therapy to enhance bladder and bowel
This study aimed to compare the two techniques for sparing the bladder and bowel. Computed tomography data from prostate cancer patients were analyzed to define the clinical target volume (CTV) and planning target volume (PTV). Treatment plans were generated with Monte Carlo algorithms, and dosimetric analysis was performed using the Monaco Treatment Planning System (TPS). We compared IMRT and VMAT for prostate cancer PTV coverage (% Ref. Volume), with VMAT showing slightly better coverage (98.885±1.704) compared to IMRT (98.594±0.923). VMAT also demonstrated improved PTV conformity. Additionally, VMAT was superior in sp...
Source: Journal of Medicine and Life - December 18, 2023 Category: General Medicine Authors: May Zeki Saddik Fatihea Fatihalla Hassan Source Type: research