Intensity-Modulated Radiation Therapy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Radiological imaging protection: a study on imaging dose used while planning computed tomography for external radiotherapy in Japan
J Radiat Res. 2023 Dec 26:rrad098. doi: 10.1093/jrr/rrad098. Online ahead of print.ABSTRACTPrevious studies have primarily focused on quality of imaging in radiotherapy planning computed tomography (RTCT), with few investigations on imaging doses. To our knowledge, this is the first study aimed to investigate the imaging dose in RTCT to determine baseline data for establishing national diagnostic reference levels (DRLs) in Japanese institutions. A survey questionnaire was sent to domestic RT institutions between 10 October and 16 December 2021. The questionnaire items were volume computed tomography dose index (CTDIvol), d...
Source: Cancer Control - December 28, 2023 Category: Cancer & Oncology Authors: Satoshi Kito Yuhi Suda Satoshi Tanabe Takeshi Takizawa Tomomasa Nagahata Naoki Tohyama Hiroyuki Okamoto Takumi Kodama Yukio Fujita Hisayuki Miyashita Kazuya Shinoda Masahiko Kurooka Hidetoshi Shimizu Takeshi Ohno Masataka Sakamoto Source Type: research

Is a total dose of 54 Gy with radiochemotherapy sufficient for treatment of intermediate-risk volumes in nasopharyngeal cancer?
ConclusionThese retrospective data suggest that a dose reduction may be possible for intermediate-risk volumes, especially for the primary site. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - December 28, 2023 Category: Cancer & Oncology Source Type: research

Machine learning-based ensemble prediction model for the gamma passing rate of VMAT-SBRT plan
Intensity-modulated radiotherapy (IMRT) techniques, including volume-modulated arc therapy (VMAT), provide highly conformal dose distribution with sharp dose falloffs to complex target volume and minimum dose to normal tissues surrounding targets. Owing to the complexity of planning and delivery, pretreatment plan verification plays a vital role in patient-specific quality assurance (QA) to assure the delivery accuracy of treatment plans. The American Association of Physicists in Medicine Task Groups 119 and 218 recommend that each treatment plan should be verified by using measurement-based methods with gamma analysis pri...
Source: Physica Medica: European Journal of Medical Physics - December 27, 2023 Category: General Medicine Authors: Wenzhao Sun, Zijie Mo, Yongbao Li, Jifeng Xiao, Lecheng Jia, Sijuan Huang, Can Liao, Jinlong Du, Shumeng He, Li Chen, Wei Zhang, Xin Yang Tags: Original paper Source Type: research

A four-dimensional dynamic conformal arc approach for real-time tumor tracking: A retrospective treatment planning study
CONCLUSIONS: A DCA-based DTT technique showed significant advantages over conventional motion encompassment treatments in lung cancer radiotherapy, with comparable performance to stricter techniques like gating and DIBH while conferring greater time-saving benefits.PMID:38146134 | DOI:10.1002/acm2.14224 (Source: Health Physics)
Source: Health Physics - December 26, 2023 Category: Physics Authors: Timothy Yau Jeff Kempe Stewart Gaede Source Type: research

A four-dimensional dynamic conformal arc approach for real-time tumor tracking: A retrospective treatment planning study
CONCLUSIONS: A DCA-based DTT technique showed significant advantages over conventional motion encompassment treatments in lung cancer radiotherapy, with comparable performance to stricter techniques like gating and DIBH while conferring greater time-saving benefits.PMID:38146134 | DOI:10.1002/acm2.14224 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - December 26, 2023 Category: Physics Authors: Timothy Yau Jeff Kempe Stewart Gaede Source Type: research

A new predictive parameter for dose-volume metrics in intensity-modulated radiation therapy planning for prostate cancer: Initial phantom study
CONCLUSIONS: POPP is superior to COPP for creating predictive models at an intermediate-dose level. Because rectal bleeding and bladder toxicity can be associated with intermediate-doses as well as high-doses, it is important to predict dose-volume metrics for various dose levels. POPP is a useful parameter for predicting dose-volume metrics and assisting the generation of treatment plans.PMID:38146130 | DOI:10.1002/acm2.14250 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - December 26, 2023 Category: Physics Authors: Yuki Saito Ryusuke Suzuki Naoki Miyamoto Kenneth Lee Sutherland Takahiro Kanehira Masaya Tamura Takashi Mori Kentaro Nishioka Takayuki Hashimoto Hidefumi Aoyama Source Type: research

A new predictive parameter for dose-volume metrics in intensity-modulated radiation therapy planning for prostate cancer: Initial phantom study
CONCLUSIONS: POPP is superior to COPP for creating predictive models at an intermediate-dose level. Because rectal bleeding and bladder toxicity can be associated with intermediate-doses as well as high-doses, it is important to predict dose-volume metrics for various dose levels. POPP is a useful parameter for predicting dose-volume metrics and assisting the generation of treatment plans.PMID:38146130 | DOI:10.1002/acm2.14250 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - December 26, 2023 Category: Cancer & Oncology Authors: Yuki Saito Ryusuke Suzuki Naoki Miyamoto Kenneth Lee Sutherland Takahiro Kanehira Masaya Tamura Takashi Mori Kentaro Nishioka Takayuki Hashimoto Hidefumi Aoyama Source Type: research

Outcomes in patients with high- and very high-risk localized prostate cancer treated with definitive IMRT and long-term hormone therapy
CONCLUSIONS: Patients with the National Comprehensive Cancer Network very high-risk prostate cancer, particularly those with Grade Group 5 and younger age, showed worse outcomes following intensity-modulated radiation therapy and long-term androgen deprivation therapy.PMID:38146119 | DOI:10.1093/jjco/hyad178 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - December 26, 2023 Category: Cancer & Oncology Authors: Norihiko Kawamura Takuji Hayashi Akira Nagahara Yasutomo Nakai Masashi Nakayama Toshiki Ikawa Naoyuki Kanayama Masahiro Morimoto Koji Konishi Kazuo Nishimura Source Type: research

A four-dimensional dynamic conformal arc approach for real-time tumor tracking: A retrospective treatment planning study
CONCLUSIONS: A DCA-based DTT technique showed significant advantages over conventional motion encompassment treatments in lung cancer radiotherapy, with comparable performance to stricter techniques like gating and DIBH while conferring greater time-saving benefits.PMID:38146134 | DOI:10.1002/acm2.14224 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - December 26, 2023 Category: Cancer & Oncology Authors: Timothy Yau Jeff Kempe Stewart Gaede Source Type: research

A four-dimensional dynamic conformal arc approach for real-time tumor tracking: A retrospective treatment planning study
CONCLUSIONS: A DCA-based DTT technique showed significant advantages over conventional motion encompassment treatments in lung cancer radiotherapy, with comparable performance to stricter techniques like gating and DIBH while conferring greater time-saving benefits.PMID:38146134 | DOI:10.1002/acm2.14224 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - December 26, 2023 Category: Physics Authors: Timothy Yau Jeff Kempe Stewart Gaede Source Type: research

Long-term disease-free survival following comprehensive involved site radiotherapy for oligometastases
CONCLUSION: Involved site radiotherapy to all areas of known disease can safely achieve durable complete remissions in patients with oligometastases treated in the real world setting. Distant failures account for the majority of treatment failures and isolated local failures are exceedingly uncommon. Oligometastases represents a promising setting to investigate novel therapeutics targeting minimal residual disease.PMID:38144534 | PMC:PMC10739409 | DOI:10.3389/fonc.2023.1267626 (Source: Cancer Control)
Source: Cancer Control - December 25, 2023 Category: Cancer & Oncology Authors: Johnny Kao Michelle Sahagian Vani Gupta Symeon Missios Ashish Sangal Source Type: research

Evaluating the Hounsfield unit assignment and dose differences between CT-based standard and deep learning-based synthetic CT images for MRI-only radiation therapy of the head and neck
CONCLUSIONS: In this cohort, HU differences of CT and sCT were observed but did not translate into a reduction in gamma pass rates or differences in average PTV/OAR dose metrics greater than 3%. For sites such as the H&N where there are many tissue interfaces we did not observe large scale dose deviations but further studies using larger retrospective cohorts are merited to establish the variation in sCT dosimetric accuracy which could help to inform QA limits on clinical sCT usage.PMID:38128040 | DOI:10.1002/acm2.14239 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - December 21, 2023 Category: Physics Authors: Kamal Singhrao Catherine Lu Dugan Christina Calvin Luis Pelayo Sue Sun Yom Jason Wing-Hong Chan Jessica Elizabeth Scholey Lisa Singer Source Type: research

Large Institutional Experience of Early Outcomes and Dosimetric Findings with Postoperative Stereotactic Partial Breast Irradiation in Breast Cancer
Accelerated partial breast irradiation (APBI) has been shown to be effective in carefully selected patients, based on evidence from at least 8 prospective randomized trials enrolling over 10,000 women[1,2]. A variety of APBI techniques have been investigated, with external beam techniques such as 3-dimensional conformal radiation therapy and intensity-modulated radiation therapy (IMRT) being favored due to their noninvasiveness and operator independence[3]. A recent meta-analysis showed that APBI was associated with significantly lower rate of acute adverse events compared to whole breast irradiation (WBI), with no differe...
Source: Radiotherapy and Oncology - December 21, 2023 Category: Radiology Authors: Jee Suk Chang, Jeongshim Lee, Frank A. Vicini, Jin Sung Kim, Jihun Kim, Seo Hee Choi, Ik Jae Lee, Yong Bae Kim Tags: Original Article Source Type: research