1 Prediction of VMAT plans deliverability to optimize patient-specific QA workload
This study aimed at reducing the patient specific QA workload of the physic team by suggesting a gamma index correlated MLC-metric to sort and prioritize the patient plans. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: M.L. Askoura, D. Dechambre, N. Depatoul, J.M. Denis, A. Delor, F. Vanneste Source Type: research

2 Complexity indexes: A new approach to limit pre-treatment checks
This study proposes a model based on complexity indexes, to predict the feasibility of treatment plans in radiotherapy with intensity modulated. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: Z.L. Jazouli, S. Muraro, D. Julian, Dr. E. Beguier, Y.F. Alaoui Source Type: research

3 Combining complexity metrics to better predict VMAT deliverability
Introduction. Use of Volumetric Arc Therapy (VMAT) is constantly growing due to its ability to deliver highly conformal dose to the target faster than most of conventional techniques. However, complexity of VMAT plans has been shown to be directly linked with delivery accuracy which is one of the reasons why systematic pre-treatment QA are usually performed before clinical treatment. In order to reduce patient-specific QA workload, numerous studies have focused on complexity metrics to see whether it can be related with VMAT deliverability. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: M. Ribeiro, Q. Dupuy, L. Bartolucci Source Type: research

4 Complexity metrics combination to optimize the pre-treatment quality assurance for IMRT and VMAT plans
Introduction. New radiotherapy technologies are associated with very complex treatments, with highly inhomogeneous beam fluences. However, plans whose intensity is strongly modulated may be too complex and the dose may be delivered improperly. In order to ensure the adequacy between the calculated dose and the dose delivered by the accelerator, pre-treatment quality assurance measurements are performed. When the difference between calculation and measurement is too important, plans need to be modified and recalculated. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: O. Bolusset, J. Fontaine, P. Retif, P. Qu étin Source Type: research

5 VMAT modulation indexes for predicting plan delivery accuracy: The ICO experience
In this study, nine modulation indexes were studied aiming to rationalize the PSQA workload for VMAT plans. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: A. Batista Camejo, A. Moignier, G. Delpon, S. Chiavassa Source Type: research

6 Evaluation of a surface imaging system to perform deep inspiration breath-hold technique for external beam radiation therapy of left-sided breast cancer
Introduction. Deep inspiration breath-hold (DIBH) technique is used to reduce cardiac doses of left-sided breast radiation therapy. We studied the accuracy and time saving of using a 3-dimensional surface imaging technique with the AlignRT system (VisionRT) to perform DIBH instead of our usually used spirometry-based system. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: D. Zarate, N. Mathy, J. Mazurier, D. Angles, J. Camilleri, D. Marre, E. Caillot, C. Chevelle, D. Franck, O. Gallocher, G. Jimenez, I. Latorzeff, B. Pichon, B. Pinel Source Type: research

7 DoseCHECK ™ algorithm evaluation used for secondary 3D dose calculation of 3DCRT and VMAT treatment plans
Introduction. DoseCHECK ™ (Sun Nuclear Corporation, Miami, FL, USA) is a collapsed cone convolution/superposition algorithm developed to perform secondary 3D dose calculation of external radiotherapy treatment plans. The purpose of this work is to evaluate the accuracy of the software on 3DCRT and VMAT treatment techniqu es. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: J. Camilleri, J. Mazurier, D. Angles, D. Marre, N. Mathy, D. Zarate, E. Caillot, C. Chevelle, D. Franck, O. Gallocher, G. Jimenez, I. Latorzeff, B. Pichon, B. Pinel Source Type: research

8 Commissioning of 4 –10 mm conical collimators with Novalis TX® using TRS 483 protocol
This study focuses on the acquisition of basic dosimetry data for the implementation of SRS using conical collimators in the TPS iPlan (BrainLab) with the main objective of minimiz ing the uncertainties about the dose delivery. The collimator output factors (OF) measurement is one of the most critical points for very small beams characterization. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: M. Lanaret, V. Chassin, J.B. Groslier, R. Gay, F. Magnier, V. Dedieu Source Type: research

9 Evaluation of the detector response in small field conditions using spectral distribution of particle fluence
Introduction. The aim of this study was to investigate the spectral distribution of particle fluence inside the detectors under small fields ’ conditions. Two PTW solid state detectors (T60019 microdiamond and T60017 E diode) and two PTW 3D PinPoint ionization chambers (T31016 and T31022) were included in this study. The investigation was carried out using Monte-Carlo simulations on a modeled TrueBeam Linac for 6MV with flattening filt er beams as well as 6MV and 10 MV flattening filter free beams. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: T. Younes, J Labour, M. Chauvin, J. Leste, L. Simon, G. Fares, L. Vieillevigne Source Type: research

10 Monte Carlo simulation of portal images for SBRT EPID-based dosimetry
Introduction. Stereotactic radiation body therapy (SBRT) treatments require the implementation of robust pre-treatment and in-vivo dosimetry methods, to which electronic portal imaging devices (EPIDs) offer an attractive solution. However, the development of EPID-based dosimetry models adapted to complex SBRT conditions is still challenging and is not completely supported for some EPID models and by commercial solutions. Therefore, in this work a detailed Monte Carlo (MC) model of the linac in combination with EPID is purposed to accurately predict the absorbed dose to the detector for further SBRT in-vivo dosimetry applic...
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: A.R. Barbeiro, J. Leste, T. Younes, L. Parent, L. Vieillevigne, R. Ferrand, J. Mazurier, A.L. Cunrath, D. Lazaro, D. Tromson, L. Simon, X. Franceries Source Type: research

11 Phase versus amplitude-gated therapy for lung SBRT with regular breathing patterns
Introduction. The aim of this study was to compare the dose delivery to the gross tumor volume (GTV), using phase- versus amplitude-gated therapy for lung Stereotactic Body Radiation Therapy (SBRT), for the patients with regular breathing patterns. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: M. Savanovi ć, D. Jaroš, F. Huguet, J.N. Foulquier Source Type: research

12 Early clinical experience of lung stereotactic body radiotherapy using deep inspiration breath-hold with real-time tumour tracking
We report on our clinical experience implementing stereotactic body radiotherapy (SBRT) for early stage non-small cell lung cancer using deep inspiration breath-hold (DIBH) and real-time tumour tracking, via implanted electromagnetic transponders (EMT). Preliminary data for our first two patients are presented, SBRT lung treatments using real-time tracking with EMT are ongoing at our institution. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: A. Dubouloz, M. Jaccard, A. Champion, J. Plojoux, P. Gasche, R. Miralbell, F. Caparrotti, G. Dipasquale Source Type: research

13 Assessment of interplay effect using a programmable motion platform
Introduction. Radiation Therapy of the thoracic region is confronted to the respiratory movement. When fluency is modulated (VMAT) and high doses (SBRT) are used, an Interplay Effect (IE) can appear. This is an unfortunate combination of the respiratory and leaf movements of the Multi-leafs Collimator that could lead to under-dosing of the target or over-dosing of risk organs. In the literature, the IE has been studied and depends on a large number of parameters: dose rate, dose per fraction, number of fractions, period and amplitude of breathing, beam energy, complexity of modulation, etc. (Source: Physica Medica: Europea...
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: I. Medjahed, J. Leste, F.X. Arnaud, L. Vieillevigne, L. Simon Source Type: research

14 Healthy tissue doses in a pulmonary stereotactic treatment using the Cyberknife: Application of two dosimetric methods
Introduction. Radiotherapy is a double-edged sword as this technique inevitably irradiates healthy tissues. This exposure may consequently trigger radio-induced complications. In recent years, assessing the risks induced by radiotherapy became a major concern as patients ’ life expectancy improves and as modern techniques irradiate a more important tissue volume 1. Risks are directly correlated to the dose delivered to the volume of healthy organs. However, precisely determining those doses remains an important challenge 2. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: J. Colnot, V. Barraux, C. Loiseau, P. Berejny, A. Batalla, R. Gschwind, C. Huet Source Type: research

15 Comparison of paraspinal metastasis SBRT plans: Cyberknife ® versus VMAT
The objective was to compare the performances of new generation linear accelerator (Linac) versus robotic radiation system dedicated for the stereotactic treatment of paraspinal tumors. Cyberknife ® plans were compared to volumetric modulated arc therapy (VMAT) plans delivered with a Versa HD®. The impact of the tumor location on the plan quality was considered. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: F. Mahinc, M. Ayadi, P. Dupuis, M.C. Biston Source Type: research

16 Dosimetric comparison of two treatment techniques (with and without intensity modulation) according to two commercial software for the treatment of brain metastases in stereotactic conditions
The objective of the present study was to compare dosimetric planning between two treatment techniques, with and without intensity modulation, using two commercial software packages, for one or two brain metastases. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: A-S. Lucia, S. Guillerm, G. Goaduff, S. Key, S. Karimi Source Type: research

17 Portal dosimetry prediction using collapsed-cone convolution model for clinical quality assurance applications
Introduction.Quality assurance (QA) of a volumetric modulated arc therapy (VMAT) plan can be performed using an amorphous silicon electronical portal imaging devices (EPIDs) to improve the QA efficiency. In our clinical routine, dosimetric plannifications are calculated with clinical treatment planning system (TPS) Pinnacle (Philips Medical Systems, Madison, WI) and transferred to Eclipse (Varian Medical Systems, Palo Alto, CA). Then a 3D recalculation is required in order to use the portal dose image prediction (PDIP) algorithm, which extends the files preparation time. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: Y. Cerbah, C. Popotte, R. Belshi, M. Fawzi Source Type: research

18 Intrafraction portal dosimetry for volumetric modulated arc therapy
Introduction.The use of in vivo portal dosimetry is widespread for the verification of delivered dose during radiotherapy. Normally this process is used for a whole fraction of radiotherapy, but if an error is encountered, a significant incorrect dose may be delivered 1,2. This is particularly relevant for hypofractionated treatments, which are forming an increasingly large proportion of treatment courses. This work therefore describes a method for portal dosimetry during delivery of a treatment fraction, with prompt notification of a discrepancy. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: J.L. Bedford, I.M. Hanson Source Type: research

19 Personalized pretreatment QA for intracranial stereotactic treatments using gel dosimetry and 3D printing of phantom: A feasibility study
Introduction.In stereotactic radiotherapy, pretreatment patient-specific quality controls (PSQA) are performed on generic phantoms to check the agreement between the dose calculated by the treatment planning system (TPS) and the measured dose by a point or 2D detector. For those controls, gel dosimetry seems a promising technique as it presents several advantages compared with conventional dosimeters such as 3D absolute dose determination with high spatial resolution 1. Thus, we investigated the feasibility of gel dosimetry in combination with a patient-based 3D printed phantom for personalized PSQA. (Source: Physica Medic...
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: J. Colnot, S. Chiavassa, G. Delpon, C. Huet Source Type: research

20 Treatment overrides: How to decrease them?
Introduction. Alarm/alert fatigue occurs when a person is exposed to a large frequency of them and consequently becomes desensitized, thus potentially leading to error. It has been found that RTTs are frequently exposed to pop-ups/alerts and as a result have to override various elements regularly. This generates weariness and a decrease in the attention to their content. An analysis of the overrides number in the Mosaiq V2.6 was launched in order to determine the content and action level of the overwritten elements and whether they led to an incident (=unjustified override). (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: V. Roosen, A. Vaandering, F. Vanneste, D. Dechambre Source Type: research

21 Performance assessment of the Calypso ® system
Introduction. The Calypso ® 4D localization system (Calypso® Medical Technologies, Seattle, Wa) is a real-time electromagnetic tracking system. It is used to continuously monitor implanted Beacon® transponders for patient alignment and target position tracking during the treatment. The purpose of the study was to assess t he performances, the accuracy and the stability of this system. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: D. Cirella, J. Prunaretty, P. Debuire, N. Aill ères, A. Morel, S. Simeon, S. Valdenaire, P. Fenoglietto Source Type: research

22- A multi-center study of breast irradiation techniques
Introduction. In France, several treatment techniques are approved for irradiation of breast and regional nodes (Hennequin et al. Recorad, 2016). A regional association of medical physicists suggested to make an inventory of the common clinical practices among its members. The study aimed to identify the irradiation techniques used and their dosimetric impact on clinical cases. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: F. Jouyaux, O. Henry, E. Biron, F. Coste, S. Danhier, M. Benchalal, P. Gesnouin, M. Getain, G. L ’Haridon P. Le Dorze, C. Le Prince, P. Lecoeur, C. Leleu, C. Llagostera, F. Le Vigouroux, E. Martin, S. Martineau, J. Palisson, S. Perrot, T. Prodhomme, A. Source Type: research

23 The growing role of Intensity Modulated Irradiation Techniques (IMRTs) in the management of breast cancer: The radiation oncologist ’s point of view
Introduction. Adjuvant breast radiation therapy is standard of care after breast conserving surgery in early breast cancer, improving disease free survival and overall survival (OS)1. Benefit of lymph node irradiation [internal mammary chain (IMC) and supra and infra clavicular nodes (SN)] in patients with axillary lymph node involvement or at high risk of relapse has been shown by a meta-analysis of three randomised trials 2. In recent years, intensity modulated radiation therapy (IMRT) has been developed to lessen organs at risk (OAR) exposure to high doses. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: Y. Kirova Source Type: research

24 VMAT technique and imaging on patients with breast cancer: The daily repositioning challenge
Introduction. Daily session positioning in radiotherapy for patients with breast cancer is a crucial step towards a better treatment delivery. Studies have demonstrated that the radiographers can use surgical clips of the tumoral bed as matching structures for patient repositioning. They evaluated the coverage for breast and tumoral bed volumes but excluded the lymph nodes from the studies. The purpose of this work is to evaluate the variation in the position of the isocenter and to compare the coverage of all target volumes using different matching structures and imaging techniques available. (Source: Physica Medica: Euro...
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: B. Baron, R. Msika, I. Birba, E. Costa Source Type: research

25 Evaluation de la m éthode de contrôle du positionnement des patientes pour le traitement des cancers du sein en VMAT
Introduction. Breast treatments with volumetric modulated arc therapy (VMAT) require an accurate positioning of the patients. The aim of this study was to assess the quality and reproducibility of our set-up method and to verify if the 5mm margin between the CTV and the PTV was appropriated. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: K. Herlevin-G érard, P. Royer, A. Ropers, I. Gehin, F. Saunier, C. Monod, V. Marchesi, I.Buchheit, C. Brunaud Source Type: research

26 Intensity modulated therapy on breast: Dosimetric and clinical results
This study presents the clinical and dosimetric results of 80 patients treated for breast cancer using intensity modulation. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: J. Ramos, F. Vincent, G. Bernadou, T. Boisserie, P.E. Cailleux, M.L. Maillet Source Type: research

27 Planning study of RA and DCA for the boost of the breast treatment
This study proposes to assess the feasibility of planning with two other techniques: RapidArc (RA) with one or two arcs and Dynamic Conformal Arc (DCA). Results of these techniques are compared to eCRT and xCRT. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: C. Cavet, T. Lacaze Source Type: research

28 Reducing contouring time of organs at risk in the thoracic and pelvic regions with innovative contouring software
Introduction. Inverse planning requires delineating a large number of Organs at Risk (OAR) which is a time-consuming process in radiotherapy. In Centre L éon Bérard (CLB), our team uses MonacoSim for more than 10 years and has a real expertise with the available tools. MiM Maestro (MiMSoftware) and Syngo.via (Siemens) were recently purchased and the associated new features (auto-contouring atlases, advanced contouring tools) were evaluated. The obj ective of this study is to evaluate the saving of time allowed by these new tools for OAR contouring in thoracic and in pelvic regions. (Source: Physica Medica: Eu...
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: A. Munoz, G. Beldjoudi Source Type: research

29 4DCT motion artifacts: Volumetric and dosimetric impacts on VMAT plans
Introduction. 4DCT is widely used for treatment planning of lung tumors, particularly to determine the necessary internal target volume (ITV). Benefits of 4DCT are limited by the presence of artifacts resulting from the acquisition and postprocessing. The aim of this study was to evaluate the volumetric and dosimetric impacts of motion artifacts on treatment planning of lung cancers. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: D. Om, B.K. Dubois, G. Moliner Source Type: research

30 Evaluation of Acuros XB dose calculation algorithm in metallic implants
Introduction. The metallic fixations affect negatively the treatment planning of radiation therapy by causing difficulties to delineate the target volume and reducing the patient absorbed dose calculation accuracy. Acuros XB (AXB) discretizes deterministically the angle, energy and space variables into grids and iteratively solves the linear Boltzmann transport equation (LBTE). The aim of this work was to evaluate Acuros XB (AXB) in presence of metallic elements, such as hip prosthesis and dental implants. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: R. Chipana, A. Arnoul Jarriault, T. Younes, L. Vieillevigne Source Type: research

31 Evaluation of auto –planning module in Pinnacle 3 of VMAT for prostate and head and neck
Introduction. The French Health Authority (HAS) has recommended Volumetric Modulation Arctherapy Treatment (VMAT) for prostate and head and neck (HN) tumors. At the Centre Clinique de la Porte de Saint Cloud, these two localization are the most common for VMAT. This technique uses inverse-planning approach, which can lead to a difference in the treatment results between two users. In order to harmonize practices and automate treatment planning, Philips propose the Auto-Planning (AP) tool for treatment planning in Pinnacle3 TPS. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: H. Miloudi, J. Le Bourhis, T.Y. P. Dinh, H. Huet De Froberville Source Type: research

32 MCO in VMAT treatment planning for locally advanced head and neck cancer
Introduction. Efficacy of inverse planning is becoming increasingly important for advanced radiotherapy techniques, and especially for head and neck cancer to decrease radiation therapy toxicity. However, the inverse planning process can create a suboptimal plan despite meeting all constraints. Multicriteria optimization (MCO) may improve doses at organs at risk (OARs) and provide better treatment planning without being time consuming. The aim of this study was therefore to evaluate the benefit of VMAT with multi-criteria optimization (MCO) in RayStation (v6.1.1.2& v8A, RaySearch Laboratories, Sweden) for head and neck...
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: J. Rolland, B. Farnault, P. Fau, A.Tallet, V. Favrel Source Type: research

33 Interstitial high dose rate brachytherapy : Commissioning and first clinical results
Introduction. At Institut de Canc érologie de l’Ouest, ear, nose and throat (ENT) tumors used to be treated by brachytherapy with 192Ir wires. Since the wire production has been stopped, 192Ir source with High Dose Rate (HDR) afterloader method has replaced the use of wires. Its implementation is evaluated by the measurement of t he first dwell position of the new applicator and dosimetric comparison between the previous and new methods. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: C. Dupuy, I. Sibide, M. Voyeau, E. Rio, C. Llagostera Source Type: research

34 Custom applicators made by 3D printer in brachytherapy: Experience of the F. Baclesse centre (Caen- France)
Introduction.Brachytherapy is a localized radiotherapy technique that uses the movement of a radioactive source near the tumor to treat it. Conventional solutions for delivering this type of treatment are the use of non-personalized applicators or the creation of personalized molded applicators, the source being guided into these applicators by catheters. The manual manufacturing process is long, tedious, with a precise positioning of the catheters in the applicator that can become a real challenge. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: C. Loiseau, V. Barraux, P. Berejny, A. Batalla, H. Austins, C. Ollivier, A. Piantino, C. Nicolas, D. Stefan, W. Kao, M. Silva, D. Lerouge Source Type: research

35 Simulation of micro-nanodosimetry spectra and free radicals with Geant4-DNA, LQD, PHYCHEML, CHEM for ion beams
This study aims at benchmarking Geant4-DNA and LQD/PHYCHEML/CHEM for the simulation of specific and lineal energy spectra and radiolysis species. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: L. Auzel, Y. Ali, C. Monini, J.M. L étang, E. Testa, M. Beuve, L. Maigne Source Type: research

36 Implementation of MIM software (adaptive module, Tomotherapy) and assessment of the planned versus delivered dose distributions for breast irradiation
Introduction. Assessing breast irradiation is a critical issue: acute and late toxicity assessment, dose homogeneity in target volumes and delivered to organs at risk. For the Tomotherapy (Accuray ®) system, the adaptive module MIM software (2017 MIM Software Inc.) - allows daily monitoring and evaluation of the dose delivered using the MVCT of each treatment session. The purpose of this project is to ensure that MIM software is reliable and then to evaluate its clinical relevance to verify the quality of the treatment by analyzing fractions administered by Tomotherapy. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: A. Djibo Sidikou, U. Niewoehner, J. Fontaine, P. Retif, P. Qu étin Source Type: research

37 Making decision for plan adaptation in rotational delivery era
Introduction. Patient ’s anatomy may change significantly during radiation treatment. A simple modification of the number of monitor units to be delivered by a particular static beam can be easily evaluated based on the change in effective depth. This approach cannot be applied in the case when radiation is delivered c ontinuously from different angles in rotational techniques as VMAT or helical tomotherapy. Our routine practice for evaluating the necessity for plan adaptation is presented. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: S. Yartsev Source Type: research

38 Assessment of dose calculation efficiency on corrected cone-beam CT images
This study aims to evaluate this method of correction (CORR-M) for dosimetric evaluation on CBCT images in case of prostate, pelvis and breast modulated treatments. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: P. Onoma, G. Delpon, S. Josset, C. Llagostera, A. Lisbona, A. Moignier, M. Voyeau, S. Chiavassa Source Type: research

39 Evaluation and comparison of CT-CBCT deformable image registration quality of two software for cervical cancer treatment
Introduction. During radiotherapy for cervical cancer, anatomical modifications can occur. Daily cone beam CT (CBCT) acquired for positioning issue, could be used to calculate the daily dose. Besides, using a cumulative strategy, it might also allow to calculate the delivered dose during treatment. For this purpose, a CT-CBCT deformable image registration (DIR) is required. The aim of this study was to investigate the quality of DIR for two software. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: S. Tahri, A. Barateau, M. Gobeli, J. Leseur, D. Williaume, R. Crevoisier, C. Herv é, E. Trifard, C. Lafond, N. Perichon Source Type: research

40 Report of the IRSN/SFPM Task Group on the implementation of an MR-linac for radiotherapy
Introduction. In the frame of the marketing of new radiation therapy devices coupling a linear electron accelerator to a magnetic resonance imaging system (MR-linac), the French Nuclear Safety Authority asked IRSN to conduct a study on the implementation of these systems. The aim was to establish the state of the art for this technology and to identify any points requiring vigilance. In particular, the study focuses on the impact of the presence of a magnetic field on the operation of a radiotherapy department (other accelerators and work organization), management of the dose delivered to the patient, including quality con...
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: S. Derreumaux, J. Caron, N. Reynaert, R. Oozeer, A. Petitfils, V. Dedieu Source Type: research

41 Deep learning in radiotherapy in 2019: what role for the medical physicist?
At early 2010 ’s, the emergence of algorithms based on deep-learning (DL) techniques revolutionized the field of artificial intelligence 1. Since then, a growing number of research works using DL for radiotherapy applications have been published. 2. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: P. Meyer, V. Noblet, A. Lallement, C. Niederst, D. Jarnet, N. Dehaynin, C. Mazzara Source Type: research

42 Gamma Index Pass Rate control limit determination using Bayesian statistical inference: application to pre-treatment quality controls[ …]
This study presents two methodologies to determine the GIPR control limit (CL). The first one is based on Bayesian inference and defines an adaptive CL to each GIPR measurement. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: T. Tiplica, S. Dufreneix, C. Legrand Source Type: research

43 From creation to clinical use of knowledge-based optimization model for breast and lymph node irradiations in volumetric modulated arc therapy, VMAT
Introduction.Treatment planning is a complex process that can result in a large number of possible dosimetric solutions. The final dose distribution depends on the geometry of organs at risk with respect to the target, differences in treatment technique, planner experience … Our work aims to describe the first steps of the creation and clinical validation of a knowledge-based treatment planning model for breast cancer irradiation using VMAT. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: T. Richir, E. Costa, M. Robilliard, P. Poortmans Source Type: research

44 Assessing the impact of key preprocessing concepts on the pseudo CT generation
Introduction. Magnetic Resonance Imaging (MRI) only radiotherapy workflows have been increasingly appealing as they ensure a reduction of the dose received by the healthy tissues and thus a higher patient safety. We used state-of-the-art 3D neural networks [1] to map any high-resolution T1-weighted MRI (T1) or enhanced T1 weighted MRI (T1Gd) to a pseudo Computed Tomography (pCT). The goal of this study was to quantify the impact of critical preprocessing steps on the 3D pCT generation. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: E. Alvarez Andres, L. Fidon, M. Vakalopoulou, G. No ël, A. Beaudre, S. Niyoteka, N. Benzazon, D. Lefkopoulos, E. Deutsch, N. Paragios, C. Robert Source Type: research

45 A comparison of pseudo-CT generation methods for prostate MRI-based dose planning: deep learning, patch-based, atlas-based and bulk-density methods
This study aims to evaluate the accuracy of two DLMs proposed to generate pCT from MRI in prostate radiotherapy: a generative adversarial network (GAN) DLM using a perceptual loss, the classical U-Net DLM and compare them with three current state-of-the art Methods. a patch-based method (PBM), an atlas-based method (ABM) and a bulk density method (BDM). (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: A. Largent, A. Barateau, J. Nunes, C. Lafond, P.B. Greer, J.A. Dowling, J. Baxter, H. Saint-Jalmes, O. Acosta, R. de Crevoisier Source Type: research

46 Deep MR to CT synthesis using paired data in the pelvic area
Introduction. The establishment of a MRI-only workflow in radiotherapy depends on the ability to generate an accurate synthetic-CT (sCT) for dose calculation. Previously proposed methods have used a Generative Adversarial Network (GAN) to generate a fast sCT in order to simplify the clinical workflow and reduce uncertainties. We used a conditional Generative Adversarial Network (cGAN) framework called pix2pixHD [1] which addresses the two main issues of a GAN: the difficulty of generating high-resolution images and the lack of details in the previous high-resolution results. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: K.N.D. Brou Boni, L. Vanquin, A. Wagner, J. Klein, D. Pasquier, N. Reynaert Source Type: research

47 Comparison of a deep learning method with three other methods to perform dose calculation from CBCT images in head-and-neck radiotherapy
This study aims to evaluate a deep learning method (DLM) to generate pseudo-CT (pCT) from CBCT and to compare this method with three existing methods in H&N cancer radiotherapy. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: A. Barateau, A. Largent, N. Perichon, J. Castelli, E. Chajon, O. Acosta, A. Simon, R. De Crevoisier, C. Lafond Source Type: research

48 Medical physicist responsibilities in internal radionuclide therapy
Introduction. The internal radionuclide therapy brings together therapy techniques using radiophamaceuticals and radioactive implants. Mostly used in oncology, two kinds of therapy techniques can be distinguished: selective and systemic methods. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: B. Farman Ara Source Type: research

49 Evaluation and optimisation of parametric reconstruction algorithms in FDG PET imaging
Introduction. Recently there has been an increased interest in whole-body dynamic PET protocols for parametric imaging, for better diagnosis and prognosis in oncology. The aim of this study is to evaluate and optimise dynamic (4D) reconstruction algorithms as opposed to standard static (3D) reconstruction algorithms for improved quantification and image quality of glucose metabolic rate parametric images for FDG PET data. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: Z. Chalampalakis, S. Stute, T. Merlin, M. Filipovic, M. Playe, C. Wimberley, C. Comtat Source Type: research

50 Counterbalancing a change of acquisition time with reconstruction parameters on numerical PET
Introduction. New numerical positron emission tomography (PET) changes the physical properties of the detection chain [1]. We studied the relationship between acquisition time (Tacq) and reconstruction parameters on a VEREOS PET/CT camera. The aim of this study was to find the most appropriate reconstruction parameters to compensate for a modification of acquisition times in clinical settings. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - December 1, 2019 Category: General Medicine Authors: C. Jaudet, G. Foucras, K. Weyts, E. Quak, R. Ciappucini, C. Lasnon, A. Batalla, S. Bardet Source Type: research