Heterogeneous PSMA ligand uptake inside parotid glands

Prostate-specific membrane antigen (PSMA) positron emission tomography (PET) is an imaging procedure primarily used for detecting prostate cancer [1], which quantifies the expression of the PSMA using radiolabeled PSMA ligands. The PSMA is a type II integral membrane protein expressed in all forms of prostate tissue, including cancerous tissue [2], with expression levels being found to increase with the stage and grade of tumours [3,4,5]. PSMA radioligands also accumulate in other body regions such as the major salivary and lacrimal glands [6,7,8], by a process postulated to be at-least partially unrelated to PSMA-mediated uptake [9,10].
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Tags: Original paper Source Type: research