Physica Medica: European Journal of Medical Physics This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Corrigendum to “A new transparent beam profiler based on secondary electrons emission for hadrontherapy charged particles beams” [Phys. Med. 68(Supplement 1) (2019) 42]
The authors regret affiliation swap (between (a) and (b)). (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - March 18, 2024 Category: General Medicine Authors: C. Thiebaux, G. Blain, B. Boyer, E. Delagnes, Y. Geerebaert, O. Gevin, F. Haddad, C. Koumeir, F. Magniette, P. Manigot, N. Michel, F. Poirier, N. Servagent, T. Sounalet, M. Verderi Tags: Corrigendum Source Type: research

Symposium on molecular radiotherapy dosimetry: The first of a series?
The European Federation of Organisations for Medical Physics (EFOMP) is an umbrella organization for 37 National Member Organisations which together represent around 10,000 medical physicists and clinical engineers working in the field of medical physics [1]. Supporting bodies of EFOMP are its 6 advisory committees, the European School for Medical Physics Experts (ESMPE), the European Journal of Medical Physics (EJMP), Working Groups and Special Interest Groups (SIGs). The first EFOMP SIG (Special Interest Group for Radionuclide Internal Dosimetry - SIG_FRID) was officially created in February 2021. (Source: Physica Medica...
Source: Physica Medica: European Journal of Medical Physics - March 17, 2024 Category: General Medicine Authors: Manuel Bardi ès, Pablo Minguez Gabiña, Glenn Flux, Pola Platoni, Efi Koutsouveli Tags: EFOMP's corner Source Type: research

Development of porous structure for broadening Bragg-peak in scanning carbon-ion radiotherapy: Monte Carlo simulation and experimental validation
Particle radiotherapy was initially proposed by Robert Wilson in the 1940  s owing to its prominent therapeutic effects [1]. As one of the particle beams, the carbon-ion beam exhibits a relatively high linear energy transfer, which leads to a superior relative biological effectiveness (RBE) compared to proton beams [2]. The Bragg peak (BP) of a pristine carbon-ion beam i s extremely sharp, especially at low penetration depths [3]. Homogeneous coverage of the target volume could be obtained by irradiating more energy layers, which increases beam delivery time [4]. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - March 16, 2024 Category: General Medicine Authors: Sixue Dong, Jiayao Sun, Xue Ming, Uli Weber, Christoph Schuy, Weigang Hu, Yinxiangzi Sheng Tags: Technical Note Source Type: research

Gold nanoparticles spectral CT imaging and limit of detectability in a new materials contrast-detail phantom
Nanomaterials offer a significant potential in the medical field for imaging and treatment of tumor and cancer cells [1]. Recent investigations have explored the potential of high atomic number (Z) nanoparticles such as gold and bismuth, as contrast agents for computed tomography (CT) [2,3]. Among these high-Z nanoparticles, gold nanoparticles (AuNPs) stand out due to their superior biocompatibility, prolonged blood circulation durations, and higher CT contrast enhancement compared to other nanoparticles [4 –6]. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - March 16, 2024 Category: General Medicine Authors: Yusuf O. Ibrahim, Nabil Maalej, Bilal Masood Pirzada, Aamir Younis Raja, Dalaver H Anjum, Nila Jan, Abderaouf Behouch, Ahsan Ul Haq Qurashi Source Type: research

Using the gamma-index analysis for inter-fractional comparison of in-beam PET images for head-and-neck treatment monitoring in proton therapy: A Monte Carlo simulation study
In-beam Positron Emission Tomography (PET) is a technique for in-vivo non-invasive treatment monitoring for proton therapy. To detect anatomical changes in patients with PET, various analysis methods exist, but their clinical interpretation is problematic. The goal of this work is to investigate whether the gamma-index analysis, widely used for dose comparisons, is an appropriate tool for comparing in-beam PET distributions. Focusing on a head-and-neck patient, we investigate whether the gamma-index map and the passing rate are sensitive to progressive anatomical changes. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - March 15, 2024 Category: General Medicine Authors: Aafke Christine Kraan, Martina Moglioni, Giuseppe Battistoni, Davide Bersani, Andrea Berti, Pietro Carra, Piergiorgio Cerello, Mario Ciocca, Veronica Ferrero, Elisa Fiorina, Enrico Mazzoni, Matteo Morrocchi, Silvia Muraro, Ester Orlandi, Francesco Pennazi Tags: Original paper Source Type: research

Inter-institutional variability of knowledge-based plan prediction of left whole breast irradiation
Radiation therapy (RT) after surgery, combined or not with chemotherapy and/or hormonal therapy, is a standard of care for breast cancer patients.[1]. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - March 13, 2024 Category: General Medicine Authors: Roberta Castriconi, Alessia Tudda, Lorenzo Placidi, Giovanna Benecchi, Elisabetta Cagni, Francesca Dusi, Anna Ianiro, Valeria Landoni, Tiziana Malatesta, Aldo Mazzilli, Guenda Meffe, Caterina Oliviero, Giulia Rambaldi Guidasci, Alessandro Scaggion, Valeri Source Type: research

Comparing interplay effects in scanned proton therapy of lung cancer: Free breathing with various layer and volume rescanning versus respiratory gating with different gate widths
Pencil beam scanning (PBS) proton therapy significantly reduces the dose to normal tissue while maintaining uniform target coverage compared with passive scattering and intensity-modulated radiotherapy [1,2]. However, an active scanning beam for a moving tumor suffers from interplay effects [3]. A previous report showed that PBS plans with a commercial treatment planning system (TPS) do not consider interplay effects and may result in reduced target coverage and overdose to organs-at-risk (OARs) during actual irradiation [4]. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - March 9, 2024 Category: General Medicine Authors: Yuki Tominaga, Masaki Suga, Mikuni Takeda, Yuki Yamamoto, Takashi Akagi, Takahiro Kato, Sunao Tokumaru, Michinori Yamamoto, Masataka Oita Source Type: research

Differentiating HCC from ICC and prediction of ICC grade based on MRI deep-radiomics: Using lesions and their extended regions
Primary liver cancer (PLC) is the sixth most common cancer worldwide and the third leading cause of cancer-related death [1]. Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are two pathological types of PLC, accounting for about 95  % [2]. In the future, the incidence of liver cancer remains expected to increase [3]. Therefore, treatment and prevention of PLC remain a huge challenge. Due to the different molecular characteristics and mechanisms between HCC and ICC, the treatment methods are different, and the prognosis of the ICC is worse than that of HCC [4]. (Source: Physica Medica: European Jo...
Source: Physica Medica: European Journal of Medical Physics - March 7, 2024 Category: General Medicine Authors: Shuping Wang, Xuehu Wang, Xiaoping Yin, Xiaoyan Lv, Jianming Cai Source Type: research

Estimating of radiation output of X-RAY tube using mathematical model: Case of high-frequency machines
Between 1869 and 1875 the British physicist William CROOKES invented one of the first electric discharge tubes named ‘’tube of Crookes’’ [1]. They are used for diagnostic (conventional radiology) and therapeutic (radiotherapy) purposes. However, the risks associated with their use depend on the dose rate received and the duration of exposure. Even at low dose rate, improper or prolonged use could cause det erministic effects (effects that occur shortly after exposure, such as burns) or stochastic effects (effects that occur days, months or even years after exposure, such as cancer and genetic mutations). (Source: P...
Source: Physica Medica: European Journal of Medical Physics - March 7, 2024 Category: General Medicine Authors: Alex Eclador Ngankem, Clemence Ra ïssa Tchatchouang Simo, Daniel Bongue, Ruth Nana Njantang, Maurice Moyo Ndontchueng, Odette Ngano Samba Source Type: research

Risk adaptive planning with biology-based constraints may lead to higher tumor control probability in tumors of the canine brain: A planning study
Classical radiation protocols are guided by physical dose delivered homogeneously over the target. Protocols are chosen to keep normal tissue complication probability (NTCP) at an acceptable level. Organs at risk (OAR) adjacent to the target volume could lead to underdosage of the tumor and a decrease of tumor control probability (TCP). The intent of our study was to explore a biology-based dose escalation: by keeping NTCP for OAR constant, radiation dose was to be maximized, allowing to result in heterogeneous dose distributions. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - March 1, 2024 Category: General Medicine Authors: Stephan Radonic, Uwe Schneider, J ürgen Besserer, Valeria S. Meier, Carla Rohrer Bley Tags: Original paper Source Type: research

A CT deep learning reconstruction algorithm: Image quality evaluation for brain protocol at decreasing dose indexes in comparison with FBP and statistical iterative reconstruction algorithms
The main concern in computed tomography (CT) examinations is the reduction of delivered dose to patients while improving the image quality. Thus, during the last years, several attempts have been made to optimise CT acquisition protocols and to develop new CT technologies [1 –5]. For many years, filtered back-projection (FBP) has been the main algorithm employed in image reconstruction until the development of Iterative Reconstruction (IR) which was mainly driven by advances in computational ability [6]. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - February 28, 2024 Category: General Medicine Authors: Silvia Tomasi, Klarisa Elena Szilagyi, Patrizio Barca, Francesca Bisello, Lorenzo Spagnoli, Sara Domenichelli, Lidia Strigari Tags: Original paper Source Type: research

End-to-end dosimetry audit for three-dimensional image-guided brachytherapy for cervical cancer
Radiation therapy dosimetry audits have a lengthy history, dating back to their initiation by the International Atomic Energy Agency in 1969 [1]. Several studies have reported the importance of dosimetry audits [2 –5]. Previous audits in radiation therapy have mainly focused on external beam radiation therapy, with less emphasis on brachytherapy [6]. Brachytherapy dosimetry is challenging due to the steep dose gradient. Initially, brachytherapy audits were limited to source strength checks [7,8]. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - February 22, 2024 Category: General Medicine Authors: Hideyuki Mizuno, Taku Nakaji, Shigekazu Fukuda, Shingo Kato Source Type: research

A time- and space-saving Monte Carlo simulation method using post-collimation generative adversarial network for dose calculation of an O-ring gantry Linac
An accurate beam model is critical for Monte Carlo (MC) simulation in radiation therapy studies. Among the various beam modeling techniques, the phase space source stands out as one of the most reliable options [1]. This method records particle properties, including energy, type, position, and direction, at a desired surface or volume in space. Achieving an acceptable simulation uncertainty necessitates a substantial number of primary particles from the phase space source, leading to storage requirements ranging from gigabytes (GB) to terabytes (TB), depending on the simulation task [2]. (Source: Physica Medica: European J...
Source: Physica Medica: European Journal of Medical Physics - February 20, 2024 Category: General Medicine Authors: Mengying Shi, Sunan Cui, Cynthia Chuang, Oluwaseyi Oderinde, Nataliya Kovalchuk, Murat Surucu, Lei Xing, Bin Han Tags: Original paper Source Type: research

Multicentric characterisation of lateral beam profiles generated by 6FFF beam of three 0.35  T MR-linac systems
Magnetic Resonance-guided Radiotherapy (MRgRT) is one of the most promising frontiers in the fight against different types of cancers [1,2]. The advent of such hybrid technology, which can combine flattening filter free (FFF) linear accelerators with on-board MR scanners, has opened up new clinical opportunities and physical challenges [3,4]. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - February 20, 2024 Category: General Medicine Authors: Menna Sebastiano, El Gawhary Randa, Placidi Lorenzo, Quaranta Flaviovincenzo, Borrazzo Cristian, Masi Marica, Nardini Matteo, Rago Maria, Indovina Luca, Cusumano Davide, Fogliata Antonella Tags: Technical Note Source Type: research

Attention-based deep neural network for partial volume correction in brain 18F-FDG PET imaging
The partial volume effect (PVE) can limit the accuracy of Positron Emission Tomography (PET) images, particularly for features that are similar in size to the spatial resolution of the system (or point spread function - PSF), leading to noticeable spill-in and spill-out across adjacent regions and resulting in obvious biases [1 –3]. Prior to the measurement of lesion/organ metabolism and physiology, partial volume correction (PVC) may be necessary to take into account signal alteration due to the limited spatial resolution of the PET system. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - February 19, 2024 Category: General Medicine Authors: MohammadSaber Azimi, Alireza Kamali-Asl, Mohammad-Reza Ay, Navid Zeraatkar, Mahboube-Sadat Hosseini, Amirhossein Sanaat, Hossein Arabi Source Type: research