Intensity-Modulated Radiation Therapy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Reirradiation salvage radiotherapy for recurrent prostate cancer after primary low-dose brachytherapy
ConclusionsOur data suggest that the treatment of locally recurrent prostate cancer with S-EBRT could provide adequate disease control safely and be used as an additional treatment in the natural history of prostate cancer patients. However, the results are still early and the sample is small; larger studies with longer follow-up would be mandatory. (Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - March 30, 2024 Category: Cancer & Oncology Source Type: research

Dosimetric comparison between carotid-sparing IMRT and 3DCRT in early glottic cancer patients treated with definitive radiation therapy
CONCLUSION: Carotid-sparing IMRT resulted in better PTV coverage and lower carotid artery dose as compared to 3DCRT in early glottic cancer patients.PMID:38554342 | DOI:10.4103/jcrt.jcrt_1912_22 (Source: Cell Research)
Source: Cell Research - March 30, 2024 Category: Cytology Authors: Harkirat Kaur Niketa Thakur Ramita Sharma Meena Sudan Neeraj Jain Supreet Kaur Priyanka Lehal Source Type: research

Primary and adjuvant intensity-modulated radiotherapy in oropharyngeal carcinoma patients from a single institution
CONCLUSION: Intensity-modulated radiotherapy for OPC is an important part of the treatment algorithm alone and in particular after surgery while the additional benefits of chemotherapy might be age dependent. Despite advanced tumor stages, nearly half of our patients were alive in the long term. The majority of patients had relatively mild chronic adverse events.PMID:38554349 | DOI:10.4103/jcrt.jcrt_2178_22 (Source: Cancer Control)
Source: Cancer Control - March 30, 2024 Category: Cancer & Oncology Authors: Henrik Hauswald Eugen Petrow Falk Roeder Juergen Debus Felix Zwicker Peter E Huber Source Type: research

Intermodality Variability in Gross Tumor Volume Delineation for Radiation Therapy Planning in Oropharyngeal Squamous Cell Carcinoma
CONCLUSIONS: Given the significant spatial variation, multimodality imaging can serve as an excellent complement for target volume delineation on CT scans during intensity modulated radiation therapy planning for LAOC by harnessing the improved soft tissue definition of MRI and the ability of PET to provide metabolic activity information.PMID:38550372 | PMC:PMC10965431 | DOI:10.1016/j.adro.2024.101453 (Source: Adv Data)
Source: Adv Data - March 29, 2024 Category: Epidemiology Authors: Thaskeen S Fathima Pooja Sethi Govindarajalou Ramkumar Dhanapathi Halanaik Smrithi Sathish Ninad Patil Source Type: research

Long-Term Patient-Reported Dyspareunia After Definitive Chemoradiation for Anal Cancer: Using the Anterior Vaginal Wall as an Organ-at-Risk to Define an Actionable Dosimetric Goal
CONCLUSIONS: Increased dose to the vaginal canal is significantly associated with worse patient-reported dyspareunia following CRT for SCCA. Minimizing dose to the AVW to V35 Gy < 60% may reduce the risk of this quality of life-limiting toxicity. Further prospective evaluation is needed to validate these findings.PMID:38550361 | PMC:PMC10966171 | DOI:10.1016/j.adro.2024.101449 (Source: Adv Data)
Source: Adv Data - March 29, 2024 Category: Epidemiology Authors: Michael K Rooney Joshua S Niedzielski Ramon M Salazar Angelica Arzola Prajnan Das Eugene J Koay Albert Koong Ethan B Ludmir Bruce D Minsky Sonal Noticewala Grace L Smith Cullen Taniguchi Emma B Holliday Source Type: research

Volumetric Response and Survival of Patients With Bulky IDH-Mutated Grade 3 Glioma Managed With FET-FDG-Guided Integrated Boost IMRT
CONCLUSION: Patients with large volume IDH-mutant Grade 3 glioma demonstrated significant tumour reduction post-IMRT, and good long-term outcomes with respect to survival and functional status. Although larger IMRT volumes were associated with poorer RFS, this was also associated with the initial volume of non-enhancing tumour.PMID:38553362 | DOI:10.1016/j.clon.2024.03.002 (Source: Cancer Control)
Source: Cancer Control - March 29, 2024 Category: Cancer & Oncology Authors: D Mills P Horsley V Venkatasha M Back Source Type: research

Impact of adaptive radiotherapy on survival in locally advanced nasopharyngeal carcinoma treated with concurrent chemoradiotherapy
CONCLUSION: Although there were differences in the patient backgrounds between the two groups, this study suggests the potential effectiveness of ART in improving locoregional control, especially in the primary tumor.PMID:38549386 | DOI:10.3857/roj.2023.00374 (Source: Cancer Control)
Source: Cancer Control - March 29, 2024 Category: Cancer & Oncology Authors: Yusuke Uchinami Koichi Yasuda Hideki Minatogawa Yasuhiro Dekura Noboru Nishikawa Rumiko Kinoshita Kentaro Nishioka Norio Katoh Takashi Mori Manami Otsuka Naoki Miyamoto Ryusuke Suzuki Keiji Kobashi Yasushi Shimizu Jun Taguchi Nayuta Tsushima Satoshi Kano Source Type: research

Grid/lattice therapy: Consideration of small field dosimetry
Br J Radiol. 2024 Mar 29:tqae060. doi: 10.1093/bjr/tqae060. Online ahead of print.ABSTRACTSmall-field dosimetry used in special procedures such as gamma knife, Cyberknife, Tomotherapy, IMRT and VMAT has been in evolution after several radiation incidences with very significant (70%) errors due to poor understanding of the dosimetry. IAEA-TRS-483 and AAPM-TG-155 have provided comprehensive information on small-fields dosimetry in terms of code of practice and relative dosimetry. Data for various detectors and conditions have been elaborated. It turns out that with a suitable detectors dose measurement accuracy can be reason...
Source: The British Journal of Radiology - March 29, 2024 Category: Radiology Authors: Indra J Das Ahtesham Ullah Khan Serpil K Dogan Mariaconcetta Longo Source Type: research

Dosimetric parameters predict radiation-induced temporal lobe necrosis in nasopharyngeal carcinoma patients: A systematic review and meta-analysis
In conclusion, this systematic review highlights the significance of dosimetric parameters, particularly Dmax and D1cc, in predicting TLN risk in NPC patients undergoing 3D-CRT, IMRT, and VMAT. The findings provide valuable insights that can help in developing optimal treatment planning strategies and contribute to the development of clinical guidelines in this field.PMID:38537680 | DOI:10.1016/j.radonc.2024.110258 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 27, 2024 Category: Radiology Authors: Jun Dong Wai Tong Ng Charlene H L Wong Ji-Shi Li Heleen Bollen James C H Chow Avraham Eisbruch Anne W M Lee Victor H F Lee Sweet Ping Ng Sandra Nuyts Robert Smee Alfio Ferlito Source Type: research