Ovarian cancer staging: What the surgeon needs to know
Br J Radiol. 2021 Jul 21:20210091. doi: 10.1259/bjr.20210091. Online ahead of print.ABSTRACTOvarian cancer (OC) is the leading cause of gynecological cancer death, and most cases are diagnosed at advanced stages due to a nonspecific and insidious clinical presentation. Radiologists play a critical role in the decision of which patients are candidates for primary debulking surgery and who may benefit from neoadjuvant chemotherapy. This pictorial review summarizes the dissemination patterns of OC, main imaging findings of metastatic disease, and which findings may alter the treatment plan or predict suboptimal tumor resectio...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Lucas Roberto Lelis Botelho de Oliveira Natally Horvat Pamela Ines Causa Andrieu Pedro Sergio Brito Panizza Giovanni Guido Cerri Publio Cesar Cavalcante Viana Source Type: research

FIELD < sup > RT < /sup > : an open-source platform for the assessment of target volume delineation in radiation therapy
CONCLUSIONS: We presented a new open-source software to support education in TVD and ongoing continuous professional development for clinical oncology trainees and consultants. ARENA in combination with FIELDRT implements site-specific modules with reference target and organs at risk volumes and automatically evaluates individual performance using several quantitative and qualitative feedbacks. Pilot results suggests this software could be used as an education tool to reduce variation in TVD so to guarantee high quality in radiotherapy.ADVANCES IN KNOWLEDGE: FIELDRT is a new easy and free to use software aiming at supporti...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Concetta Piazzese Elin Evans Betsan Thomas John Staffurth Sarah Gwynne Emiliano Spezi Source Type: research

Development and validation of a multiparametric MRI-based radiomics signature for distinguishing between indolent and aggressive prostate cancer
Br J Radiol. 2021 Jul 21:20210191. doi: 10.1259/bjr.20210191. Online ahead of print.ABSTRACTOBJECTIVES: To develop and validate a noninvasive MRI-based radiomics signature for distinguishing between indolent and aggressive prostate cancer (PCa) prior to therapy.METHODS: In all, 139 qualified and pathology-confirmed PCa patients were divided into a training set (n = 93) and a validation set (n = 46). A total of 1576 radiomics features were extracted from the T2WI (n = 788) and DWI (n = 788) for each patient. The Select K Best and the least absolute shrinkage and selection operator (LASSO) regression algorithm were used to c...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Liuhui Zhang Donggen Jiang Chujie Chen Xiangwei Yang Hanqi Lei Zhuang Kang Hai Huang Jun Pang Source Type: research

A radiological diagnostic approach to tumours and tumour-like lesions of the calcaneus
CONCLUSION: Our algorithm should help the radiologist narrow down the differential diagnosis when evaluating calcaneal lesions.ADVANCES IN KNOWLEDGE: This article provides a radiological approach to calcaneal lesions.PMID:34289323 | DOI:10.1259/bjr.20210330 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Christine Azzopardi Anish Patel Steven James Rajesh Botchu Mark Davies Source Type: research

A real-world study evaluating ultrasound guided percutaneous non-targeted liver biopsy needle failures and pathology sample quality assessment in both end-cut and side-notch needles
CONCLUSION: Ultrasound-guided liver biopsy is safe and sample quality is consistently good when a core>20 mm long is obtained. The end-cut biopsy device generated reliably good quality biopsy samples, however the needle failure rate was significantly higher than the side-cut needle.ADVANCES IN KNOWLEDGE: Ultrasound guided liver biopsy specimen quality is consistently good when a core>20 mm long is obtained which can be achieved with a single pass using the 16G BiopinceTM end-cut needle, although the needle failure rate is significantly higher than the 16G Max-Core™ Bard™ side-notch needle.PMID:34289324 | ...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Jim Zhong Rachel Allard Dominic Hewitson Michael Weston Oliver Hulson Simon Burbidge Hannah Lambie Tom Kaye Judith I Wyatt Raneem Albazaz Source Type: research

Radiation concerns in frequent flyer patients: Should imaging history influence decisions about recurrent imaging?
Br J Radiol. 2021 Jul 21:20210543. doi: 10.1259/bjr.20210543. Online ahead of print.ABSTRACTRadiation risks from diagnostic imaging have captured the attention of patients and medical practitioners alike, yet it remains unclear how these considerations can best be incorporated into clinical decision making. This manuscript presents a framework to consider these issues in a potentially at-risk population, the so called "frequent flyer" patients undergoing a large amount of recurrent imaging over time. Radiation risks from the low-dose exposures of diagnostic imaging are briefly reviewed, as applied to recurrent ex...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Aaron D Sodickson Source Type: research

MRI findings in-between leiomyoma and leiomyosarcoma: a Rad-Path correlation of degenerated leiomyomas and variants
Br J Radiol. 2021 Jul 21:20210283. doi: 10.1259/bjr.20210283. Online ahead of print.ABSTRACTLeiomyomas are the most common benign tumors of the uterus. On the opposite side, leiomyosarcomas are rare malignant uterine tumors that account for a significant proportion of uterine cancer deaths. Especially when large and degenerated, leiomyomas and leiomyoma variants can have overlapping imaging characteristics with those of leiomyosarcomas. Although not always possible, it is paramount to be able to differentiate between leiomyomas and leiomyosarcomas on imaging, as the therapeutic management can differ. This pictorial review ...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Vlad Bura Roxana Maria Pintican Reka Emma David Helen Clare Addley Janette Smith Mercedes Jimenez-Linan Janice Lee Susan Freeman Carmen Georgiu Source Type: research

Ovarian cancer staging: What the surgeon needs to know
Br J Radiol. 2021 Jul 21:20210091. doi: 10.1259/bjr.20210091. Online ahead of print.ABSTRACTOvarian cancer (OC) is the leading cause of gynecological cancer death, and most cases are diagnosed at advanced stages due to a nonspecific and insidious clinical presentation. Radiologists play a critical role in the decision of which patients are candidates for primary debulking surgery and who may benefit from neoadjuvant chemotherapy. This pictorial review summarizes the dissemination patterns of OC, main imaging findings of metastatic disease, and which findings may alter the treatment plan or predict suboptimal tumor resectio...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Lucas Roberto Lelis Botelho de Oliveira Natally Horvat Pamela Ines Causa Andrieu Pedro Sergio Brito Panizza Giovanni Guido Cerri Publio Cesar Cavalcante Viana Source Type: research

FIELD < sup > RT < /sup > : an open-source platform for the assessment of target volume delineation in radiation therapy
CONCLUSIONS: We presented a new open-source software to support education in TVD and ongoing continuous professional development for clinical oncology trainees and consultants. ARENA in combination with FIELDRT implements site-specific modules with reference target and organs at risk volumes and automatically evaluates individual performance using several quantitative and qualitative feedbacks. Pilot results suggests this software could be used as an education tool to reduce variation in TVD so to guarantee high quality in radiotherapy.ADVANCES IN KNOWLEDGE: FIELDRT is a new easy and free to use software aiming at supporti...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Concetta Piazzese Elin Evans Betsan Thomas John Staffurth Sarah Gwynne Emiliano Spezi Source Type: research

Development and validation of a multiparametric MRI-based radiomics signature for distinguishing between indolent and aggressive prostate cancer
Br J Radiol. 2021 Jul 21:20210191. doi: 10.1259/bjr.20210191. Online ahead of print.ABSTRACTOBJECTIVES: To develop and validate a noninvasive MRI-based radiomics signature for distinguishing between indolent and aggressive prostate cancer (PCa) prior to therapy.METHODS: In all, 139 qualified and pathology-confirmed PCa patients were divided into a training set (n = 93) and a validation set (n = 46). A total of 1576 radiomics features were extracted from the T2WI (n = 788) and DWI (n = 788) for each patient. The Select K Best and the least absolute shrinkage and selection operator (LASSO) regression algorithm were used to c...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Liuhui Zhang Donggen Jiang Chujie Chen Xiangwei Yang Hanqi Lei Zhuang Kang Hai Huang Jun Pang Source Type: research

A radiological diagnostic approach to tumours and tumour-like lesions of the calcaneus
CONCLUSION: Our algorithm should help the radiologist narrow down the differential diagnosis when evaluating calcaneal lesions.ADVANCES IN KNOWLEDGE: This article provides a radiological approach to calcaneal lesions.PMID:34289323 | DOI:10.1259/bjr.20210330 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Christine Azzopardi Anish Patel Steven James Rajesh Botchu Mark Davies Source Type: research

A real-world study evaluating ultrasound guided percutaneous non-targeted liver biopsy needle failures and pathology sample quality assessment in both end-cut and side-notch needles
CONCLUSION: Ultrasound-guided liver biopsy is safe and sample quality is consistently good when a core>20 mm long is obtained. The end-cut biopsy device generated reliably good quality biopsy samples, however the needle failure rate was significantly higher than the side-cut needle.ADVANCES IN KNOWLEDGE: Ultrasound guided liver biopsy specimen quality is consistently good when a core>20 mm long is obtained which can be achieved with a single pass using the 16G BiopinceTM end-cut needle, although the needle failure rate is significantly higher than the 16G Max-Core™ Bard™ side-notch needle.PMID:34289324 | ...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Jim Zhong Rachel Allard Dominic Hewitson Michael Weston Oliver Hulson Simon Burbidge Hannah Lambie Tom Kaye Judith I Wyatt Raneem Albazaz Source Type: research

Radiation concerns in frequent flyer patients: Should imaging history influence decisions about recurrent imaging?
Br J Radiol. 2021 Jul 21:20210543. doi: 10.1259/bjr.20210543. Online ahead of print.ABSTRACTRadiation risks from diagnostic imaging have captured the attention of patients and medical practitioners alike, yet it remains unclear how these considerations can best be incorporated into clinical decision making. This manuscript presents a framework to consider these issues in a potentially at-risk population, the so called "frequent flyer" patients undergoing a large amount of recurrent imaging over time. Radiation risks from the low-dose exposures of diagnostic imaging are briefly reviewed, as applied to recurrent ex...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Aaron D Sodickson Source Type: research

MRI findings in-between leiomyoma and leiomyosarcoma: a Rad-Path correlation of degenerated leiomyomas and variants
Br J Radiol. 2021 Jul 21:20210283. doi: 10.1259/bjr.20210283. Online ahead of print.ABSTRACTLeiomyomas are the most common benign tumors of the uterus. On the opposite side, leiomyosarcomas are rare malignant uterine tumors that account for a significant proportion of uterine cancer deaths. Especially when large and degenerated, leiomyomas and leiomyoma variants can have overlapping imaging characteristics with those of leiomyosarcomas. Although not always possible, it is paramount to be able to differentiate between leiomyomas and leiomyosarcomas on imaging, as the therapeutic management can differ. This pictorial review ...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Vlad Bura Roxana Maria Pintican Reka Emma David Helen Clare Addley Janette Smith Mercedes Jimenez-Linan Janice Lee Susan Freeman Carmen Georgiu Source Type: research

Ovarian cancer staging: What the surgeon needs to know
Br J Radiol. 2021 Jul 21:20210091. doi: 10.1259/bjr.20210091. Online ahead of print.ABSTRACTOvarian cancer (OC) is the leading cause of gynecological cancer death, and most cases are diagnosed at advanced stages due to a nonspecific and insidious clinical presentation. Radiologists play a critical role in the decision of which patients are candidates for primary debulking surgery and who may benefit from neoadjuvant chemotherapy. This pictorial review summarizes the dissemination patterns of OC, main imaging findings of metastatic disease, and which findings may alter the treatment plan or predict suboptimal tumor resectio...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Lucas Roberto Lelis Botelho de Oliveira Natally Horvat Pamela Ines Causa Andrieu Pedro Sergio Brito Panizza Giovanni Guido Cerri Publio Cesar Cavalcante Viana Source Type: research

FIELD < sup > RT < /sup > : an open-source platform for the assessment of target volume delineation in radiation therapy
CONCLUSIONS: We presented a new open-source software to support education in TVD and ongoing continuous professional development for clinical oncology trainees and consultants. ARENA in combination with FIELDRT implements site-specific modules with reference target and organs at risk volumes and automatically evaluates individual performance using several quantitative and qualitative feedbacks. Pilot results suggests this software could be used as an education tool to reduce variation in TVD so to guarantee high quality in radiotherapy.ADVANCES IN KNOWLEDGE: FIELDRT is a new easy and free to use software aiming at supporti...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Concetta Piazzese Elin Evans Betsan Thomas John Staffurth Sarah Gwynne Emiliano Spezi Source Type: research

Development and validation of a multiparametric MRI-based radiomics signature for distinguishing between indolent and aggressive prostate cancer
Br J Radiol. 2021 Jul 21:20210191. doi: 10.1259/bjr.20210191. Online ahead of print.ABSTRACTOBJECTIVES: To develop and validate a noninvasive MRI-based radiomics signature for distinguishing between indolent and aggressive prostate cancer (PCa) prior to therapy.METHODS: In all, 139 qualified and pathology-confirmed PCa patients were divided into a training set (n = 93) and a validation set (n = 46). A total of 1576 radiomics features were extracted from the T2WI (n = 788) and DWI (n = 788) for each patient. The Select K Best and the least absolute shrinkage and selection operator (LASSO) regression algorithm were used to c...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Liuhui Zhang Donggen Jiang Chujie Chen Xiangwei Yang Hanqi Lei Zhuang Kang Hai Huang Jun Pang Source Type: research

A radiological diagnostic approach to tumours and tumour-like lesions of the calcaneus
CONCLUSION: Our algorithm should help the radiologist narrow down the differential diagnosis when evaluating calcaneal lesions.ADVANCES IN KNOWLEDGE: This article provides a radiological approach to calcaneal lesions.PMID:34289323 | DOI:10.1259/bjr.20210330 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Christine Azzopardi Anish Patel Steven James Rajesh Botchu Mark Davies Source Type: research

A real-world study evaluating ultrasound guided percutaneous non-targeted liver biopsy needle failures and pathology sample quality assessment in both end-cut and side-notch needles
CONCLUSION: Ultrasound-guided liver biopsy is safe and sample quality is consistently good when a core>20 mm long is obtained. The end-cut biopsy device generated reliably good quality biopsy samples, however the needle failure rate was significantly higher than the side-cut needle.ADVANCES IN KNOWLEDGE: Ultrasound guided liver biopsy specimen quality is consistently good when a core>20 mm long is obtained which can be achieved with a single pass using the 16G BiopinceTM end-cut needle, although the needle failure rate is significantly higher than the 16G Max-Core™ Bard™ side-notch needle.PMID:34289324 | ...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Jim Zhong Rachel Allard Dominic Hewitson Michael Weston Oliver Hulson Simon Burbidge Hannah Lambie Tom Kaye Judith I Wyatt Raneem Albazaz Source Type: research

Radiation concerns in frequent flyer patients: Should imaging history influence decisions about recurrent imaging?
Br J Radiol. 2021 Jul 21:20210543. doi: 10.1259/bjr.20210543. Online ahead of print.ABSTRACTRadiation risks from diagnostic imaging have captured the attention of patients and medical practitioners alike, yet it remains unclear how these considerations can best be incorporated into clinical decision making. This manuscript presents a framework to consider these issues in a potentially at-risk population, the so called "frequent flyer" patients undergoing a large amount of recurrent imaging over time. Radiation risks from the low-dose exposures of diagnostic imaging are briefly reviewed, as applied to recurrent ex...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Aaron D Sodickson Source Type: research

MRI findings in-between leiomyoma and leiomyosarcoma: a Rad-Path correlation of degenerated leiomyomas and variants
Br J Radiol. 2021 Jul 21:20210283. doi: 10.1259/bjr.20210283. Online ahead of print.ABSTRACTLeiomyomas are the most common benign tumors of the uterus. On the opposite side, leiomyosarcomas are rare malignant uterine tumors that account for a significant proportion of uterine cancer deaths. Especially when large and degenerated, leiomyomas and leiomyoma variants can have overlapping imaging characteristics with those of leiomyosarcomas. Although not always possible, it is paramount to be able to differentiate between leiomyomas and leiomyosarcomas on imaging, as the therapeutic management can differ. This pictorial review ...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Vlad Bura Roxana Maria Pintican Reka Emma David Helen Clare Addley Janette Smith Mercedes Jimenez-Linan Janice Lee Susan Freeman Carmen Georgiu Source Type: research

Ovarian cancer staging: What the surgeon needs to know
Br J Radiol. 2021 Jul 21:20210091. doi: 10.1259/bjr.20210091. Online ahead of print.ABSTRACTOvarian cancer (OC) is the leading cause of gynecological cancer death, and most cases are diagnosed at advanced stages due to a nonspecific and insidious clinical presentation. Radiologists play a critical role in the decision of which patients are candidates for primary debulking surgery and who may benefit from neoadjuvant chemotherapy. This pictorial review summarizes the dissemination patterns of OC, main imaging findings of metastatic disease, and which findings may alter the treatment plan or predict suboptimal tumor resectio...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Lucas Roberto Lelis Botelho de Oliveira Natally Horvat Pamela Ines Causa Andrieu Pedro Sergio Brito Panizza Giovanni Guido Cerri Publio Cesar Cavalcante Viana Source Type: research

FIELD < sup > RT < /sup > : an open-source platform for the assessment of target volume delineation in radiation therapy
CONCLUSIONS: We presented a new open-source software to support education in TVD and ongoing continuous professional development for clinical oncology trainees and consultants. ARENA in combination with FIELDRT implements site-specific modules with reference target and organs at risk volumes and automatically evaluates individual performance using several quantitative and qualitative feedbacks. Pilot results suggests this software could be used as an education tool to reduce variation in TVD so to guarantee high quality in radiotherapy.ADVANCES IN KNOWLEDGE: FIELDRT is a new easy and free to use software aiming at supporti...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Concetta Piazzese Elin Evans Betsan Thomas John Staffurth Sarah Gwynne Emiliano Spezi Source Type: research

Development and validation of a multiparametric MRI-based radiomics signature for distinguishing between indolent and aggressive prostate cancer
Br J Radiol. 2021 Jul 21:20210191. doi: 10.1259/bjr.20210191. Online ahead of print.ABSTRACTOBJECTIVES: To develop and validate a noninvasive MRI-based radiomics signature for distinguishing between indolent and aggressive prostate cancer (PCa) prior to therapy.METHODS: In all, 139 qualified and pathology-confirmed PCa patients were divided into a training set (n = 93) and a validation set (n = 46). A total of 1576 radiomics features were extracted from the T2WI (n = 788) and DWI (n = 788) for each patient. The Select K Best and the least absolute shrinkage and selection operator (LASSO) regression algorithm were used to c...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Liuhui Zhang Donggen Jiang Chujie Chen Xiangwei Yang Hanqi Lei Zhuang Kang Hai Huang Jun Pang Source Type: research

A radiological diagnostic approach to tumours and tumour-like lesions of the calcaneus
CONCLUSION: Our algorithm should help the radiologist narrow down the differential diagnosis when evaluating calcaneal lesions.ADVANCES IN KNOWLEDGE: This article provides a radiological approach to calcaneal lesions.PMID:34289323 | DOI:10.1259/bjr.20210330 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Christine Azzopardi Anish Patel Steven James Rajesh Botchu Mark Davies Source Type: research

A real-world study evaluating ultrasound guided percutaneous non-targeted liver biopsy needle failures and pathology sample quality assessment in both end-cut and side-notch needles
CONCLUSION: Ultrasound-guided liver biopsy is safe and sample quality is consistently good when a core>20 mm long is obtained. The end-cut biopsy device generated reliably good quality biopsy samples, however the needle failure rate was significantly higher than the side-cut needle.ADVANCES IN KNOWLEDGE: Ultrasound guided liver biopsy specimen quality is consistently good when a core>20 mm long is obtained which can be achieved with a single pass using the 16G BiopinceTM end-cut needle, although the needle failure rate is significantly higher than the 16G Max-Core™ Bard™ side-notch needle.PMID:34289324 | ...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Jim Zhong Rachel Allard Dominic Hewitson Michael Weston Oliver Hulson Simon Burbidge Hannah Lambie Tom Kaye Judith I Wyatt Raneem Albazaz Source Type: research

Radiation concerns in frequent flyer patients: Should imaging history influence decisions about recurrent imaging?
Br J Radiol. 2021 Jul 21:20210543. doi: 10.1259/bjr.20210543. Online ahead of print.ABSTRACTRadiation risks from diagnostic imaging have captured the attention of patients and medical practitioners alike, yet it remains unclear how these considerations can best be incorporated into clinical decision making. This manuscript presents a framework to consider these issues in a potentially at-risk population, the so called "frequent flyer" patients undergoing a large amount of recurrent imaging over time. Radiation risks from the low-dose exposures of diagnostic imaging are briefly reviewed, as applied to recurrent ex...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Aaron D Sodickson Source Type: research

MRI findings in-between leiomyoma and leiomyosarcoma: a Rad-Path correlation of degenerated leiomyomas and variants
Br J Radiol. 2021 Jul 21:20210283. doi: 10.1259/bjr.20210283. Online ahead of print.ABSTRACTLeiomyomas are the most common benign tumors of the uterus. On the opposite side, leiomyosarcomas are rare malignant uterine tumors that account for a significant proportion of uterine cancer deaths. Especially when large and degenerated, leiomyomas and leiomyoma variants can have overlapping imaging characteristics with those of leiomyosarcomas. Although not always possible, it is paramount to be able to differentiate between leiomyomas and leiomyosarcomas on imaging, as the therapeutic management can differ. This pictorial review ...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Vlad Bura Roxana Maria Pintican Reka Emma David Helen Clare Addley Janette Smith Mercedes Jimenez-Linan Janice Lee Susan Freeman Carmen Georgiu Source Type: research

Ovarian cancer staging: What the surgeon needs to know
Br J Radiol. 2021 Jul 21:20210091. doi: 10.1259/bjr.20210091. Online ahead of print.ABSTRACTOvarian cancer (OC) is the leading cause of gynecological cancer death, and most cases are diagnosed at advanced stages due to a nonspecific and insidious clinical presentation. Radiologists play a critical role in the decision of which patients are candidates for primary debulking surgery and who may benefit from neoadjuvant chemotherapy. This pictorial review summarizes the dissemination patterns of OC, main imaging findings of metastatic disease, and which findings may alter the treatment plan or predict suboptimal tumor resectio...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Lucas Roberto Lelis Botelho de Oliveira Natally Horvat Pamela Ines Causa Andrieu Pedro Sergio Brito Panizza Giovanni Guido Cerri Publio Cesar Cavalcante Viana Source Type: research

FIELD < sup > RT < /sup > : an open-source platform for the assessment of target volume delineation in radiation therapy
CONCLUSIONS: We presented a new open-source software to support education in TVD and ongoing continuous professional development for clinical oncology trainees and consultants. ARENA in combination with FIELDRT implements site-specific modules with reference target and organs at risk volumes and automatically evaluates individual performance using several quantitative and qualitative feedbacks. Pilot results suggests this software could be used as an education tool to reduce variation in TVD so to guarantee high quality in radiotherapy.ADVANCES IN KNOWLEDGE: FIELDRT is a new easy and free to use software aiming at supporti...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Concetta Piazzese Elin Evans Betsan Thomas John Staffurth Sarah Gwynne Emiliano Spezi Source Type: research

Development and validation of a multiparametric MRI-based radiomics signature for distinguishing between indolent and aggressive prostate cancer
Br J Radiol. 2021 Jul 21:20210191. doi: 10.1259/bjr.20210191. Online ahead of print.ABSTRACTOBJECTIVES: To develop and validate a noninvasive MRI-based radiomics signature for distinguishing between indolent and aggressive prostate cancer (PCa) prior to therapy.METHODS: In all, 139 qualified and pathology-confirmed PCa patients were divided into a training set (n = 93) and a validation set (n = 46). A total of 1576 radiomics features were extracted from the T2WI (n = 788) and DWI (n = 788) for each patient. The Select K Best and the least absolute shrinkage and selection operator (LASSO) regression algorithm were used to c...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Liuhui Zhang Donggen Jiang Chujie Chen Xiangwei Yang Hanqi Lei Zhuang Kang Hai Huang Jun Pang Source Type: research

A radiological diagnostic approach to tumours and tumour-like lesions of the calcaneus
CONCLUSION: Our algorithm should help the radiologist narrow down the differential diagnosis when evaluating calcaneal lesions.ADVANCES IN KNOWLEDGE: This article provides a radiological approach to calcaneal lesions.PMID:34289323 | DOI:10.1259/bjr.20210330 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Christine Azzopardi Anish Patel Steven James Rajesh Botchu Mark Davies Source Type: research

A real-world study evaluating ultrasound guided percutaneous non-targeted liver biopsy needle failures and pathology sample quality assessment in both end-cut and side-notch needles
CONCLUSION: Ultrasound-guided liver biopsy is safe and sample quality is consistently good when a core>20 mm long is obtained. The end-cut biopsy device generated reliably good quality biopsy samples, however the needle failure rate was significantly higher than the side-cut needle.ADVANCES IN KNOWLEDGE: Ultrasound guided liver biopsy specimen quality is consistently good when a core>20 mm long is obtained which can be achieved with a single pass using the 16G BiopinceTM end-cut needle, although the needle failure rate is significantly higher than the 16G Max-Core™ Bard™ side-notch needle.PMID:34289324 | ...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Jim Zhong Rachel Allard Dominic Hewitson Michael Weston Oliver Hulson Simon Burbidge Hannah Lambie Tom Kaye Judith I Wyatt Raneem Albazaz Source Type: research

Radiation concerns in frequent flyer patients: Should imaging history influence decisions about recurrent imaging?
Br J Radiol. 2021 Jul 21:20210543. doi: 10.1259/bjr.20210543. Online ahead of print.ABSTRACTRadiation risks from diagnostic imaging have captured the attention of patients and medical practitioners alike, yet it remains unclear how these considerations can best be incorporated into clinical decision making. This manuscript presents a framework to consider these issues in a potentially at-risk population, the so called "frequent flyer" patients undergoing a large amount of recurrent imaging over time. Radiation risks from the low-dose exposures of diagnostic imaging are briefly reviewed, as applied to recurrent ex...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Aaron D Sodickson Source Type: research

MRI findings in-between leiomyoma and leiomyosarcoma: a Rad-Path correlation of degenerated leiomyomas and variants
Br J Radiol. 2021 Jul 21:20210283. doi: 10.1259/bjr.20210283. Online ahead of print.ABSTRACTLeiomyomas are the most common benign tumors of the uterus. On the opposite side, leiomyosarcomas are rare malignant uterine tumors that account for a significant proportion of uterine cancer deaths. Especially when large and degenerated, leiomyomas and leiomyoma variants can have overlapping imaging characteristics with those of leiomyosarcomas. Although not always possible, it is paramount to be able to differentiate between leiomyomas and leiomyosarcomas on imaging, as the therapeutic management can differ. This pictorial review ...
Source: The British Journal of Radiology - July 21, 2021 Category: Radiology Authors: Vlad Bura Roxana Maria Pintican Reka Emma David Helen Clare Addley Janette Smith Mercedes Jimenez-Linan Janice Lee Susan Freeman Carmen Georgiu Source Type: research

Prostate hypofractionated radiotherapy (62Gy at 3.1Gy per fraction) with injection of hyaluronic acid: final results of the RPAH1 study
CONCLUSION: Despite the inefficacy of HA injection was not rejected, we observed the absence of Grade 3 or 4 rectal toxicity as well as a rate of Grade 2 rectal bleeding below 10% at 36 months of follow-up. Late urinary toxicities are the most frequent but the rate decreases largely at 3 years.ADVANCES IN KNOWLEDGE: With an injection of HA, hypofractionated irradiation in 4 weeks is well tolerated with no Grade 3 or 4 GI toxicity and a rate of Grade 2 rectal bleeding below 10% at 36 months of follow-up.PMID:34282946 | DOI:10.1259/bjr.20210242 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 20, 2021 Category: Radiology Authors: Olivier Chapet Corina Udrescu Sylvie Bin Evelyne Decullier Pascal Fenoglietto Amandine Beneux Bruno Segui Ciprian Enachescu Sonya Gaudioz Alain Ruffion David Azria Source Type: research

CBCT imaging: a simple approach for optimising and evaluating concomitant imaging doses, based on patient-specific attenuation, during radiotherapy pelvis treatment
CONCLUSION: Patient-specific CBCT modes are in use clinically with dose reductions across all modes except Pelvis XL, keeping doses ALARP and images optimal. Consideration of OAR doses controls the number of CBCTs allowed to ensure adherence to OAR tolerance. Reporting CBCT doses in "scans per Gray" allows clinicians to make informed decisions regarding the imaging schedule and concomitant doses.ADVANCES IN KNOWLEDGE: Patient grouping at planning CT, using CTDIvol, allows for CBCT imaging protocols to be selected based on patient specific attenuation. Reporting OAR doses in terms of "scans per Gray" all...
Source: The British Journal of Radiology - July 20, 2021 Category: Radiology Authors: Caroline Ord óñez-Sanz Mark Cowen Neda Shiravand Niall D MacDougall Source Type: research

Radiotherapy CT-based contouring atlas for non-malignant skeletal and soft tissue disorders: a practical proposal from Spanish experience
CONCLUSIONS: This comprehensive atlas based on CT images may be of value to radiation oncologists who wish to use LD-RT for the symptomatic treatment of degenerative or inflammatory osteoarticular diseases.ADVANCES IN KNOWLEDGE: The recommendations and contouring atlas described in this article provide an eminently practical tool for LD-RT in non-malignant conditions, based on the same quality criteria recommended for all modern radiotherapy treatments in Spain.PMID:34282948 | DOI:10.1259/bjr.20200809 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 20, 2021 Category: Radiology Authors: Beatriz Alvarez Angel Montero Ovidio Hernando Raquel Ciervide Juan Garcia Mercedes Lopez Mariola Garcia-Aranda Xin Chen Ines Flores Emilio Sanchez Jeannette Valero Alejandro Prado Rosa Alonso Leyre Alonso Pedro Fernandez-Leton Carmen Rubio Source Type: research

Radiology teaching within the undergraduate medical curriculum: medical students' perspective
Br J Radiol. 2021 Jul 20:20210797. doi: 10.1259/bjr.20210797. Online ahead of print.NO ABSTRACTPMID:34283636 | DOI:10.1259/bjr.20210797 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 20, 2021 Category: Radiology Authors: Haris Shoaib Harmeet Singh Makan Faeez Ramjan Yunus Kaleem Hussain Muhammad S Ali Source Type: research

Impact of hydrogel peri-rectal spacer insertion on seminal vesicles intrafraction motion during 1.5  T-MRI-guided adaptive stereotactic body radiotherapy for localized prostate cancer
CONCLUSIONS: A favorable impact of the hydrogel-spacer on seminal vesicles motion was observed only in cranio-caudal translational shifts, although being not clinically significant. Further studies are required to fully investigate the potential contribution of this device on vesicles motion.ADVANCES IN KNOWLEDGE: MR-guided daily adaptive radiotherapy may represent a game changer for prostate stereotactic body radiotherapy, given the possibility to better visualize soft-tissues anatomy and to daily recalculate the treatment plan based on real-time conditions. The use of devices like rectal ballon or rectal gel spacers has ...
Source: The British Journal of Radiology - July 20, 2021 Category: Radiology Authors: Rosario Mazzola Gianluisa Sicignano Francesco Cuccia Claudio Vitale Michele Rigo Niccol ò Giaj-Levra Luca Nicosia Vanessa Figlia Francesco Ricchetti Giorgio Attin à Edoardo Pastorello Antonio De Simone Davide Gurrera Stefania Naccarato Ruggero Ruggieri Source Type: research

Dosimetric feasibility of stereotactic irradiation of primary prostate cancer at 5x9 Gy with a method of urethral sparing
CONCLUSION: A SBRT dose-escalation to 5 × 9 Gy on the prostate while sparing the urethra + 2 mm at 36.25 Gy is feasible without compromising dose coverage to the tumor. This radiation regimen will be used for a Phase-III trial.ADVANCES IN KNOWLEDGE: In prostate SBRT, dose optimization on the urethra is feasible and could decrease urinary toxicities.PMID:34283647 | DOI:10.1259/bjr.20210142 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 20, 2021 Category: Radiology Authors: Salim Benhmida Amandine Beneux Corina Udrescu Olivier Rouviere Samy Horn Ciprian Enachescu Ariane Lapierre Olivier Chapet Source Type: research

Prostate hypofractionated radiotherapy (62Gy at 3.1Gy per fraction) with injection of hyaluronic acid: final results of the RPAH1 study
CONCLUSION: Despite the inefficacy of HA injection was not rejected, we observed the absence of Grade 3 or 4 rectal toxicity as well as a rate of Grade 2 rectal bleeding below 10% at 36 months of follow-up. Late urinary toxicities are the most frequent but the rate decreases largely at 3 years.ADVANCES IN KNOWLEDGE: With an injection of HA, hypofractionated irradiation in 4 weeks is well tolerated with no Grade 3 or 4 GI toxicity and a rate of Grade 2 rectal bleeding below 10% at 36 months of follow-up.PMID:34282946 | DOI:10.1259/bjr.20210242 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 20, 2021 Category: Radiology Authors: Olivier Chapet Corina Udrescu Sylvie Bin Evelyne Decullier Pascal Fenoglietto Amandine Beneux Bruno Segui Ciprian Enachescu Sonya Gaudioz Alain Ruffion David Azria Source Type: research

CBCT imaging: a simple approach for optimising and evaluating concomitant imaging doses, based on patient-specific attenuation, during radiotherapy pelvis treatment
CONCLUSION: Patient-specific CBCT modes are in use clinically with dose reductions across all modes except Pelvis XL, keeping doses ALARP and images optimal. Consideration of OAR doses controls the number of CBCTs allowed to ensure adherence to OAR tolerance. Reporting CBCT doses in "scans per Gray" allows clinicians to make informed decisions regarding the imaging schedule and concomitant doses.ADVANCES IN KNOWLEDGE: Patient grouping at planning CT, using CTDIvol, allows for CBCT imaging protocols to be selected based on patient specific attenuation. Reporting OAR doses in terms of "scans per Gray" all...
Source: The British Journal of Radiology - July 20, 2021 Category: Radiology Authors: Caroline Ord óñez-Sanz Mark Cowen Neda Shiravand Niall D MacDougall Source Type: research

Radiotherapy CT-based contouring atlas for non-malignant skeletal and soft tissue disorders: a practical proposal from Spanish experience
CONCLUSIONS: This comprehensive atlas based on CT images may be of value to radiation oncologists who wish to use LD-RT for the symptomatic treatment of degenerative or inflammatory osteoarticular diseases.ADVANCES IN KNOWLEDGE: The recommendations and contouring atlas described in this article provide an eminently practical tool for LD-RT in non-malignant conditions, based on the same quality criteria recommended for all modern radiotherapy treatments in Spain.PMID:34282948 | DOI:10.1259/bjr.20200809 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 20, 2021 Category: Radiology Authors: Beatriz Alvarez Angel Montero Ovidio Hernando Raquel Ciervide Juan Garcia Mercedes Lopez Mariola Garcia-Aranda Xin Chen Ines Flores Emilio Sanchez Jeannette Valero Alejandro Prado Rosa Alonso Leyre Alonso Pedro Fernandez-Leton Carmen Rubio Source Type: research

Radiology teaching within the undergraduate medical curriculum: medical students' perspective
Br J Radiol. 2021 Jul 20:20210797. doi: 10.1259/bjr.20210797. Online ahead of print.NO ABSTRACTPMID:34283636 | DOI:10.1259/bjr.20210797 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 20, 2021 Category: Radiology Authors: Haris Shoaib Harmeet Singh Makan Faeez Ramjan Yunus Kaleem Hussain Muhammad S Ali Source Type: research

Impact of hydrogel peri-rectal spacer insertion on seminal vesicles intrafraction motion during 1.5  T-MRI-guided adaptive stereotactic body radiotherapy for localized prostate cancer
CONCLUSIONS: A favorable impact of the hydrogel-spacer on seminal vesicles motion was observed only in cranio-caudal translational shifts, although being not clinically significant. Further studies are required to fully investigate the potential contribution of this device on vesicles motion.ADVANCES IN KNOWLEDGE: MR-guided daily adaptive radiotherapy may represent a game changer for prostate stereotactic body radiotherapy, given the possibility to better visualize soft-tissues anatomy and to daily recalculate the treatment plan based on real-time conditions. The use of devices like rectal ballon or rectal gel spacers has ...
Source: The British Journal of Radiology - July 20, 2021 Category: Radiology Authors: Rosario Mazzola Gianluisa Sicignano Francesco Cuccia Claudio Vitale Michele Rigo Niccol ò Giaj-Levra Luca Nicosia Vanessa Figlia Francesco Ricchetti Giorgio Attin à Edoardo Pastorello Antonio De Simone Davide Gurrera Stefania Naccarato Ruggero Ruggieri Source Type: research

Dosimetric feasibility of stereotactic irradiation of primary prostate cancer at 5x9 Gy with a method of urethral sparing
CONCLUSION: A SBRT dose-escalation to 5 × 9 Gy on the prostate while sparing the urethra + 2 mm at 36.25 Gy is feasible without compromising dose coverage to the tumor. This radiation regimen will be used for a Phase-III trial.ADVANCES IN KNOWLEDGE: In prostate SBRT, dose optimization on the urethra is feasible and could decrease urinary toxicities.PMID:34283647 | DOI:10.1259/bjr.20210142 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 20, 2021 Category: Radiology Authors: Salim Benhmida Amandine Beneux Corina Udrescu Olivier Rouviere Samy Horn Ciprian Enachescu Ariane Lapierre Olivier Chapet Source Type: research

Neoadjuvant chemoradiotherapy plus postoperative adjuvant XELOX chemotherapy versus postoperative adjuvant chemotherapy with XELOX regimen for local advanced gastric cancer-A randomized, controlled study
CONCLUSIONS: NACRT combined with postoperative adjuvant XELOX chemotherapy can improve R0 resection rate, reduce loco-regional recurrence, prolong PFS and FFLP without increasing the incidence of postoperative complications in patients with LAGC.ADVANCES IN KNOWLEDGE: Compared with postoperative adjuvant chemotherapy, locally advanced gastric cancer patients may benefit from neoadjuvant chemoradiotherapy, and toxicity associated with chemoradiotherapy was tolerant and manageable.PMID:34260297 | DOI:10.1259/bjr.20201088 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 14, 2021 Category: Radiology Authors: Fuli Wang Aizhong Qu Yinping Sun Jifeng Zhang Benzun Wei Yong Cui Xiao Liu Wei Tian Yan Li Source Type: research

The eyes see what the mind seeks: a systematic review of abdominal imaging findings in patients with COVID-19
CONCLUSION: This systematic review provides insight into the abdominal imaging findings in patients with COVID-19. Knowledge of these imaging manifestations will not only help in further research but also will aid in curtailing transmission of the SARS-CoV-2. Further prospective studies are needed to gain better insight into the pathophysiology of these imaging manifestations.ADVANCES IN KNOWLEDGE: This review highlights the abdominal imaging findings in patients with COVID-19, to gain insight into the disease pathophysiology and gear the abdominal radiologist through the pandemic.PMID:34260323 | DOI:10.1259/bjr.20201220 (...
Source: The British Journal of Radiology - July 14, 2021 Category: Radiology Authors: Lokesh Agarwal Ayushi Agarwal Shailesh Advani Varidh Katiyar Aprajita Chaturvedi Kumble Seetharama Madhusudhan Source Type: research

Neoadjuvant chemoradiotherapy plus postoperative adjuvant XELOX chemotherapy versus postoperative adjuvant chemotherapy with XELOX regimen for local advanced gastric cancer-A randomized, controlled study
CONCLUSIONS: NACRT combined with postoperative adjuvant XELOX chemotherapy can improve R0 resection rate, reduce loco-regional recurrence, prolong PFS and FFLP without increasing the incidence of postoperative complications in patients with LAGC.ADVANCES IN KNOWLEDGE: Compared with postoperative adjuvant chemotherapy, locally advanced gastric cancer patients may benefit from neoadjuvant chemoradiotherapy, and toxicity associated with chemoradiotherapy was tolerant and manageable.PMID:34260297 | DOI:10.1259/bjr.20201088 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 14, 2021 Category: Radiology Authors: Fuli Wang Aizhong Qu Yinping Sun Jifeng Zhang Benzun Wei Yong Cui Xiao Liu Wei Tian Yan Li Source Type: research