Multiparametric quantitative analysis of tumor perfusion and diffusion with 3t MRI: Differentiation between benign and malignant soft tissue tumors.
Abstract OBJECTIVES: To evaluate multiparametric magnetic resonance imaging (MRI) for differentiating benign and malignant soft tissue tumors. METHODS: This retrospective study included 67 patients (mean age, 55 years; 18-82 years) with 35 benign and 32 malignant soft tissue tumors. Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI)-derived parameters (D, D*, f), apparent diffusion coefficient (ADC), and dynamic contrast-enhanced (DCE)-MRI parameters (Ktrans, Kep, Ve, iAUC) were calculated. Myxoid and non-myxoid soft tissue tumors were divided for subgroup analysis. The parameters were compare...
Source: The British Journal of Radiology - July 10, 2020 Category: Radiology Authors: Lee SK, Jee WH, Jung CK, Chung YG Tags: Br J Radiol Source Type: research

Differentiation of salivary gland tumor using diffusion-weighted imaging with a fractional order calculus model.
Abstract OBJECTIVE: To evaluate the feasibility of using imaging parameters (D, β and μ) obtained from fractional order calculus (FROC) diffusion model to differentiate salivary gland tumors. METHODS: 15 b-value (0-2000 s/mm2) diffusion-weighted imaging (DWI) was scanned in 62 patients with salivary gland tumors (47 benign and 15 malignant). Diffusion coefficient D, fractional order parameter β (which correlates with tissue heterogeneity) and a microstructural quantity μ of the solid portion within the tumor were calculated, and compared between benign and malignant groups, or among ple...
Source: The British Journal of Radiology - July 10, 2020 Category: Radiology Authors: Chen W, Zhu LN, Dai YM, Jiang JS, Bu SS, Xu XQ, Wu FY Tags: Br J Radiol Source Type: research

Patient reported cosmetic outcome after vacuum assisted excision of benign breast lesions: a cross-sectional study.
CONCLUSION: In this study VAE is safe and effective for tumors up to 5 cm and patient reported cosmetic outcome was good. Patients with benign lesions could benefit from VAE as an alternative for surgical excision. ADVANCES IN KNOWLEDGE: A formal quantitative measurement of cosmetic outcome after vacuum assisted excision for benign breast lesions was still lacking. This study shows that this cosmetic outcome is overall good in benign lesions up to 5 cm. PMID: 32649240 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 10, 2020 Category: Radiology Authors: van de Voort EMF, Klem TMAL, Struik GM, Birnie E, Sinke RHJA, Ghandi A Tags: Br J Radiol Source Type: research

Virtual monoenergetic images preserve diagnostic assessability in contrast media reduced abdominal spectral detector CT.
CONCLUSIONS: VMI40keV counteract contrast deterioration in contrast media reducedabdominal SDCT, facilitating diagnostic assessment. ADVANCES IN KNOWLEDGE: SDCT-derived VMI40keV provide adequate depiction of vessels, organs and lymph nodes even at notable contrast media reduction. PMID: 32644824 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 8, 2020 Category: Radiology Authors: Lennartz S, Hokam NG, Zäske C, Zopfs D, Bratke G, Glauner A, Maintz D, Persigehl T, Chang DH, Hickethier T Tags: Br J Radiol Source Type: research

Biomarkers of pituitary macroadenomas aggressive behaviour: a conventional MRI and DWI 3T study.
CONCLUSION: Adding quantitative measures of ADC values to cMRI could be used routinely as a non-invasive marker of specific predictive biomarker of the proliferative activity of PA. ADVANCES IN KNOWLEDGE: Routinely use of DWI on diagnostic work-up of pituitary adenomas may help in establish the likely biological aggressive lesions. PMID: 32628097 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 6, 2020 Category: Radiology Authors: Conficoni A, Feraco P, Mazzatenta D, Zoli M, Asioli S, Zenesini C, Fabbri VP, Cellerini M, Bacci A Tags: Br J Radiol Source Type: research

Voxel based evaluation of sequential radiotherapy treatment plans with different dose fractionation schemes.
CONCLUSION: The proposed methodology using the VRb tool offers superior plan evaluation for multiphase sequential radiotherapy treatment plans over the existing methods. ADVANCES IN KNOWLEDGE: PTV, CTV and OAR priority based display modes in VRb tool offers better understanding of radiobiological evaluation of sequential radiotherapy treatment plans. PMID: 32614607 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 2, 2020 Category: Radiology Authors: Singh G, Kamal R, Thaper D, Oinam AS, Handa B, Kumar V, Kumar N Tags: Br J Radiol Source Type: research

Can t2 blackout effect be A marker of iron accumulation in brains of multiple sclerosis patients ?: A qualitative study.
CONCLUSIONS: TBO shows correlation with the conditions which were revealed to be associated with iron accumulation in thebrain of MS patients in theliterature. Therefore, we concluded that TBO and its severity in DGM may represent iron accumulation in MS brains. ADVANCES IN KNOWLEDGE: TBO effect as a frequent imaging finding in dailypractice, may be used as predictor of the disease course of multiple sclerosis due to possible effects of iron accumulation in brain and thereby, may be useful in modifying treatment strategies. PMID: 32614611 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 1, 2020 Category: Radiology Authors: Erbay MF, Kamışlı Ö, Karatoprak NB Tags: Br J Radiol Source Type: research

Consensus survey on Pre-procedural safety practices in radiological examinations: A multicenter study in seven asian regions.
CONCLUSION: Based on the responses from 21 participating Asian institutions, most routinely perform standard practices during radiological examinations except when it comes to examination appropriateness. This study can provide direction for safety policymakers scrutinizing and improving regional standards of care. ADVANCES IN KNOWLEDGE: This is the first multicenter survey study to elucidate pre-procedural safety practices in radiological examinations in seven Asian regions. PMID: 32584595 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - June 25, 2020 Category: Radiology Authors: Lee YH, Quek ST, Khong PL, Lee CS, Wu JS, Zhang L, Ng KH, Yang SO, Kudo K, Do KH, Kim SH, Chen DC, Cheng A, Leung JH, Chang YC, Hsu HH, Chan WP Tags: Br J Radiol Source Type: research

Pulmonary artery enlargement on routine staging 18F-fluodeoxyglucose positron emission tomography/CT for lung and oesophageal cancer.
CONCLUSION: Simple measurements of mPA diameter and PA:A ratio reveal that lung cancer patients exhibit increased rates of pulmonary artery enlargement compared to oesophageal cancer patients. ADVANCES IN KNOWLEDGE: This study demonstrates there is an increased prevalence of pulmonary enlargement in lung cancer, easily detected on routine, staging scans holding implications for further work-up and risk stratification. PMID: 32584599 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - June 25, 2020 Category: Radiology Authors: Ji-Xu A, Yang Y, Bradley KM Tags: Br J Radiol Source Type: research

Imaging findings in coronavirus infections: SARS-CoV, MERS-CoV, and SARS-CoV-2.
Abstract During the first two decades of the 21st century, there have been three coronavirus infection outbreaks raising global health concerns by severe acute respiratory syndrome coronavirus (SARS-CoV), the Middle East respiratory syndrome coronavirus (MERS-CoV), and the SARS-CoV-2. Although the reported imaging findings of coronavirus infection are variable and nonspecific, the most common initial chest radiograph (CXR) and computed tomography (CT) findings are ground-glass opacities and consolidation with peripheral predominance and eventually spread to involve both lungs as the disease progresses. These findi...
Source: The British Journal of Radiology - June 25, 2020 Category: Radiology Authors: Franquet T, Jeong YJ, Lam HYS, Wong HYF, Chang YC, Chung MJ, Lee KS Tags: Br J Radiol Source Type: research

Contrast agent accumulation patterns in chronic interstitial lung disease using 5d MRI.
CONCLUSIONS: Contrast agent dynamics are influenced by type and severity of pulmonary fibrosis, which might enable a more thorough characterization of disease burden. The regional impairment is of particular interest in the context of antifibrotic treatments and was characterized using a non-invasive, non-irradiating, free-breathing method. ADVANCES IN KNOWLEDGE: Delayed contrast enhancement patterns allow the assessment of regional lung impairment which could represent different disease stages or phenotypes in ILD. PMID: 32584606 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - June 25, 2020 Category: Radiology Authors: Maria Ta B, Andreas W, Christopher M R, Michael K, Claus Peter H, Mark K, Julien D Tags: Br J Radiol Source Type: research

Comparison of 18F-FDG PET-MR and fecal biomarkers in the assessment of disease activity in patients with ulcerative colitis.
This study was conducted under the framework of a single-center clinical trial (clinicaltrials.gov [NCT03781284]). N = 50 participants were enrolled. Fecal samples were collected before bowel preparation. All patients underwent whole-body 18F-FDG PET-MR followed by ileocolonoscopy within 24 h. Diagnostic performance of five fecal biomarkers (calprotectin, lactoferrin, polymorphonuclear leukocyte elastase, S100A12 and eosinophil-derived neurotoxin), MR morphological parameters (MRmorph), diffusion-weighted imaging and PET in detecting active disease determined by Rachmilewitz endoscopic activity index (EAI) were eval...
Source: The British Journal of Radiology - June 24, 2020 Category: Radiology Authors: Li Y, Khamou M, Schaarschmidt BM, Umutlu L, Forsting M, Demircioglu A, Haubold J, Koch AK, Bruckmann NM, Sawicki LM, Herrmann K, Boone JH, Langhorst J Tags: Br J Radiol Source Type: research

The diagnostic performance of CESM and CE-MRI in evaluating the pathological response to neoadjuvant therapy in breast cancer: A systematic review and meta-analysis.
CONCLUSIONS: Compared to CE-MRI, CESM has equal specificity, greater sensitivity and excellent performance, which may have a brighter prospect in evaluating the pathological response of breast cancer to NAC. ADVANCES IN KNOWLEDGE: CESM showed equal specificity, greater sensitivity and excellent performance than CE-MRI. PMID: 32574075 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - June 23, 2020 Category: Radiology Authors: Tang S, Xiang C, Yang Q Tags: Br J Radiol Source Type: research

Multimodality imaging of adult rhabdomyosarcoma: the added value of hybrid imaging.
Abstract Rhabdomyosarcoma (RMS) represents more than 50% of paediatric soft tissue tumours. Conversely, it is extremely rare among adults, where it shows peculiar biological and clinical features that are still poorly investigated. RMS patients should be referred to a Sarcoma Centre, where the contribution of experienced radiologists plays a relevant role in the diagnostic assessment of the disease, including precise localisation, staging, image-guided biopsy, response evaluation after treatment and follow-up. Besides CT and MRI, hybrid imaging including positron emission tomography (PET)/CT and PET/MRI are giving...
Source: The British Journal of Radiology - June 19, 2020 Category: Radiology Authors: Gennaro N, Marrari A, Renne SL, Cananzi F, Quagliuolo VL, Di Brina L, Scorsetti M, Pepe G, Chiti A, Santoro A, Balzarini L, Politi LS, Bertuzzi AF Tags: Br J Radiol Source Type: research

Linear Mixed-effects models for estimation of pulmonary metastasis growth rate: implications for CT surveillance in patients with sarcoma.
CONCLUSIONS: Assuming a 2 mm nodule is the smallest reliably detectable nodule by CT, the data suggest that an untreated pulmonary metastasis is expected to grow to 8 mm in 8.4 months (95% CI (4.9, 10.2) months). Tumor size, grade and sarcoma subtype did not significantly alter pulmonary metastasis growth rate. However, chemotherapy slowed the pulmonary metastasis growth rate. ADVANCES IN KNOWLEDGE: CT surveillance intervals for pulmonary metastases can be estimated based on metastasis growth rate. There was significant variation in the pulmonary metastasis growth rate between metastases within pa...
Source: The British Journal of Radiology - June 19, 2020 Category: Radiology Authors: Isidro U, O'Brien LM, Sebro R Tags: Br J Radiol Source Type: research

Bad neighbours: hypoxia and genomic instability in prostate cancer.
Abstract Prostate cancer (PCa) is a clinically heterogeneous disease and has poor patient outcome when tumours progress to castration-resistant and metastatic states. Understanding the mechanistic basis for transition to late stage aggressive disease is vital for both assigning patient risk status in the localised setting and also identifying novel treatment strategies to prevent progression. Subregions of intratumoral hypoxia are found in all solid tumours and are associated with many biologic drivers of tumour progression. Crucially, more recent findings show the co-presence of hypoxia and genomic instability ca...
Source: The British Journal of Radiology - June 18, 2020 Category: Radiology Authors: Ashton J, Bristow R Tags: Br J Radiol Source Type: research

Is percutaneous image-guided renal tumour ablation ready for prime time?
Abstract In the last few decades, thermal ablation (TA) techniques have been increasingly applied to treat small localized renal cell carcinomas (RCC). Despite this trend, there is still an underuse of TA compared to surgery and a substantial lack of high-quality evidence derived from large, prospective, randomized controlled trials comparing the long-term oncologic outcomes of TA and surgery. Therefore, in this narrative review, we assess published guidelines and recent literature concerning the diagnosis and management of kidney-confined RCC to understand whether percutaneous image-guided TA is ready to be propo...
Source: The British Journal of Radiology - June 16, 2020 Category: Radiology Authors: Cazzato RL, Garnon J, De Marini P, Auloge P, Koch G, Dalili D, Buy X, Palussiere J, Rao PP, Tricard T, Lang H, Gangi A Tags: Br J Radiol Source Type: research

Primary operator radiation dose in the cardiac catheter laboratory.
This study sought to investigate operator radiation dose for a range of procedures and different operators in order to investigate trends and optimise dose. METHODS: Real time dosimeters (RTDs) were worn by operators for angiography procedures for 3 years. Dose area product (DAP) and RTD were collected. RTD was normalised to DAP (RTD/DAP) to compare radiation dose and radiation protection measures. Comparisons were made across procedure categories and individual operators. RESULTS: In 7626 procedures, median and 75thpercentile levels were established for operator dose for 8 procedure categories. There was a signi...
Source: The British Journal of Radiology - June 16, 2020 Category: Radiology Authors: Crowhurst JA, Whitby M, Aroney N, Dautov R, Walters D, Raffel O Tags: Br J Radiol Source Type: research

Comparison of radiographer interobserver image registration variability using cone beam CT and MR for cervix radiotherapy.
CONCLUSION: The magnitude of interobserver variations between CBCT-CT and MR-CT were similar, confirming that MR-CT radiotherapy workflows are comparable to CBCT-CT image-guided radiotherapy. Our results suggest MR-MR radiotherapy workflows may be a superior registration strategy. ADVANCES IN KNOWLEDGE: This is the first publication quantifying interobserver registration of multimodality image registration strategies for cervix radical radiotherapy patients. PMID: 32543946 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - June 16, 2020 Category: Radiology Authors: Rodgers J, Hales R, Whiteside L, Parker J, McHugh L, Cree A, van Herk M, Choudhury A, Hoskin P, McWilliam A, Eccles CL Tags: Br J Radiol Source Type: research

Evaluation of genitourinary fistulas in pelvic malignancies with etiopathologic correlation: role of cross sectional imaging in detection and management.
CONCLUSION: Imaging findings significantly influence the management and outcome of genitourinary fistulas in pelvic malignancies. Contrast-enhanced CT is the imaging modality of choice in the evaluation of pelvic fistulas associated with malignancies and MRI is complimentary to it. ADVANCES IN KNOWLEDGE: To our knowledge, this study is the first of its kind wherein the mean duration of occurrence of fistulas in pelvic malignancies is correlated with the underlying etiopathology. PMID: 32539548 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - June 15, 2020 Category: Radiology Authors: Mandava A, Koppula V, Sharma G, Kandati M, Raju KVVN, Subramanyeshwar Rao T Tags: Br J Radiol Source Type: research

Left-right breast asymmetry and risk of screen-detected and interval cancers in a large population-based screening population.
CONCLUSIONS: Increased DV asymmetry was associated with the risk of a breast cancer diagnosis at a contemporaneous screen or as an interval cancer. BV asymmetry was positively associated with the risk of an interval cancer diagnosis. ADVANCES IN KNOWLEDGE: The findings suggest that DV and BV asymmetry may provide additional signals for detecting contemporaneous cancers and assessing the likelihood of interval cancers in population-based screening programmes. PMID: 32525693 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - June 11, 2020 Category: Radiology Authors: Hudson SM, Wilkinson LS, De Stavola BL, Dos-Santos-Silva I Tags: Br J Radiol Source Type: research

Diagnostic value and forensic relevance of a novel photorealistic 3d reconstruction technique in postmortem computed tomography.
Aissa J Abstract OBJECTIVES: Evaluation of performance and forensic relevance of a novel, photorealistic, 3D reconstruction method (Cinematic Rendering, CR) in comparison to conventional postmortem computed tomography (PMCT) and Volume Rendering (VR) technique for visualization of traumatic injuries. METHODS: 112 pathologies (fractures, soft tissue injuries and foreign bodies) from 33 human cadavers undergoing whole body PMCT after traumatic death were retrospectively analyzed. Pathologies were reconstructed with CR and VR technique. Fractures were classified according to their dislocation. Images were evalua...
Source: The British Journal of Radiology - June 11, 2020 Category: Radiology Authors: Böven J, Boos J, Steuwe A, Morawitz J, Sawicki LM, Caspers J, Küppers L, Hartung B, Thomas C, Antoch G, Aissa J Tags: Br J Radiol Source Type: research

Survival prediction for oral tongue cancer patients via probabilistic genetic algorithm optimized neural network models.
CONCLUSIONS: The work demonstrated that the proposed probabilistic genetic algorithm optimized neural network models, integrating with the t-SNE dimensionality reduction algorithm, achieved accurate prediction of patient survival. ADVANCES IN KNOWLEDGE: Theproposed Probabilistic Genetic Algorithm-Back Propagation (PGA-BP) neural network, integrating with an advanced dimensionality reduction algorithm (t-SNE), improved patient survival prediction accuracy using pre-treatment quantitative CT image features of head-and-neck cancer patients. PMID: 32520585 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - June 10, 2020 Category: Radiology Authors: Pan X, Zhang T, Yang Q, Yang D, Qi XS Tags: Br J Radiol Source Type: research

CT guided radiofrequency ablation of osteoid osteoma: Established concepts and new ideas.
Abstract Osteoid osteoma is a painful benign bone tumor of children and young adults with characteristic clinico-radiological features depending upon the location of the lesion. Intra operative visualization of the nidus is difficult and therefore curative surgery is often associated with excessive bone removal, significant perioperative morbidity and potential need of bone grafting procedures. With advancement in cross-sectional imaging and radiofrequency ablation (RFA) technology, CT guided RFA has emerged as the treatment of choice for the osteoid osteoma. This procedure involves accurate cannulation of the nid...
Source: The British Journal of Radiology - June 10, 2020 Category: Radiology Authors: Singh DK, Katyan A, Kumar N, Nigam K, Jaiswal B, Misra RN Tags: Br J Radiol Source Type: research

Impact of dosimetric differences between computed tomography (CT) and magnetic resonance imaging (MRI) derived target volumes for external beam cervical cancer radiotherapy.
CONCLUSIONS: The dosimetric differences of CT and MRI based contouring variability for this study was small.CT remains the standard imaging modality for volume delineation for these patients. ADVANCES IN KNOWLEDGE: This is the first study to evaluate the dosimetric implications of imaging modality on target and organ at risk doses in cervical cancer EBRT. PMID: 32516544 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - June 9, 2020 Category: Radiology Authors: Batumalai V, Burke S, Roach D, Lim K, Dinsdale G, Jameson M, Ochoa C, Veera J, Holloway L, Vinod S Tags: Br J Radiol Source Type: research

Clinical utility of fat-suppressed 3-dimensional controlled aliasing in parallel imaging results in higher acceleration sampling perfection with application optimized contrast using different flip angle evolutions MRI of the knee in adults.
Abstract OBJECTIVE: To compare 3D CAIPIRINHA SPACE and 2D TSE MRI in the diagnosis of knee pathology in symptomatic adult patients. METHODS: From February to September in 2018, 120 patientswho underwent a knee MRI using both 3D CAIPIRINHA SPACE and 2D TSE MRI were enrolled. The signal-to-noise ratios (SNR) and contrast to noise ratio (CNR) of the 2D and 3D MRI were compared using a paired t-test. Two radiologists independently evaluated both 2D and 3D MRI images using scoring systems for the menisci, ligaments, and cartilage. Inter method, inter and intra reader agreements were determined using an intra class...
Source: The British Journal of Radiology - June 9, 2020 Category: Radiology Authors: Lee S, Lee GY, Kim S, Park YB, Lee HJ Tags: Br J Radiol Source Type: research

Radiological features and management of retained needles - a pictorial review.
Abstract The identification of retained needles is essential because of their sharp structure with possible life threatening complications. However, radiological evaluation could be challenging, especially in case of needles' relatively poor conspicuity and small dimension. This pictorial essay focuses on clinical issues (needle features, retention mechanisms and associated complications) and technical aspects (choice of the best diagnostic modality and technique) that can lead the radiologist to an earlier and proper diagnosis of needle retention in order to provide the best treatment for the patient. PMID: ...
Source: The British Journal of Radiology - June 9, 2020 Category: Radiology Authors: Contegiacomo A, Conti M, Trombatore P, Dezio M, Muciaccia M, Lozupone E, Natale L, Manfredi R Tags: Br J Radiol Source Type: research

Staging of bladder cancer with multiparametric MRI.
Abstract The distinction of non-muscle-invasive bladder cancer and muscle-invasive bladder cancer is important for the selection of the optimal treatment. Multiparametric MRI (mp-MRI) has been an useful modality for the T staging of bladder cancer, and a systematic evaluation of mp-MRI is needed. The Vesical Imaging Reporting and Data System was designed to standardize the scanning and reporting criteria based on mp-MRI for clinical and research applications. This review briefly describes the method, interpretation, and timing of mp-MRI examinations in the clinical settings. Validation studies of Vesical Imaging R...
Source: The British Journal of Radiology - June 9, 2020 Category: Radiology Authors: Juri H, Narumi Y, Panebianco V, Osuga K Tags: Br J Radiol Source Type: research

Increased visceral adipose tissue in clear cell renal cell carcinoma with and without peritumoral collateral vessels.
In this study, we quantify VAT in male patients with clear cell renal cell carcinoma (ccRCC) subgrouped according to the presence or absence of peritumoral collateral vessels. METHODS: in this retrospective study, we enrolled 141 male caucasian patients divided into 2 groups: the ccRCC group (n = 106) composed of patients with ccRCC and control group (n = 35). The ccRCC group was further divided into two subgroups: the ccRCCa subgroup which showed absence of collateral vessels (n = 48) and ccRCCp subgroup with collateral vessels (n = 58).Total adipose tissue (TAT) area, VAT area and subcutaneous adipose tissue (SAT) a...
Source: The British Journal of Radiology - June 9, 2020 Category: Radiology Authors: Greco F, Quarta LG, Grasso RF, Beomonte Zobel B, Mallio CA Tags: Br J Radiol Source Type: research

Non-neoplastic conditions mimicking peritoneal carcinomatosis at CT imaging.
Abstract The generalappearance of peritoneal carcinomatosis at abdominal CT and other cross-sectional imaging modalities consists of varying amounts of peritoneal-based soft tissue implants (mass-forming or infiltrative), peritoneal fluid, and occasionally calcification. However, a wide variety of common and uncommon neoplastic and non-neoplastic conditions can closely mimic peritoneal carcinomatosis at imaging. Neoplastic mimics of peritoneal carcinomatosis include primary peritoneal and sub peritoneal tumors, as well as peritoneal lymphomatosis and sarcomatosis.Broad categories of non-neoplastic mimics of perito...
Source: The British Journal of Radiology - June 9, 2020 Category: Radiology Authors: Elmohr MM, Elsayes KM, Pickhardt P Tags: Br J Radiol Source Type: research

A review of the PERFORMS scheme in breast screening.
Abstract This review details the aetiology of the PERFORMS self-assessment scheme in breast screening, together with its subsequent development, current implementation and future function. The purpose of the scheme is examined and the importance of its continuing role in a changing screening service described, together with current evolution. PMID: 32501766 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - June 5, 2020 Category: Radiology Authors: Gale A, Chen Y Tags: Br J Radiol Source Type: research

A half-century of innovation in technology - preparing MRI for the 21st century.
DG Abstract MRI developed during the last half century from a very basic concept to an indispensable non-ionising medical imaging technique that has found broad application in diagnostics, therapy control and far beyond. Due to its excellent soft-tissue contrast and the huge variety of accessible tissue- and physiological-parameters, MRI is often preferred to other existing modalities. In the course of its development MRI underwent many substantial transformations. From the beginning, starting as a proof of concept, much effort was expended to develop the appropriate basic scanning technology and methodology, and...
Source: The British Journal of Radiology - June 4, 2020 Category: Radiology Authors: Börnert P, Norris DG Tags: Br J Radiol Source Type: research

Evolution of radiation protection for medical workers.
Abstract Within a few months of discovery, x-rays were being used worldwide for diagnosis and within a year or two for therapy. It became clear very quickly that while there were immense benefits there were significant associated hazards, not only for the patients, but also for the operators of the equipment. Simple radiation protection measures were implemented within a decade or two and radiation protection for physicians and other operators has continued to evolve over the last century driven by cycles of widening uses, new technologies, realization of previously unidentified effects, development of recommendat...
Source: The British Journal of Radiology - June 4, 2020 Category: Radiology Authors: Boice J, Dauer LT, Kase KR, Mettler FA, Vetter RJ Tags: Br J Radiol Source Type: research

Defining short and prolonged breath-holds.
PMID: 32484713 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - June 2, 2020 Category: Radiology Authors: Parkes M, Cashmore J, Green S, Clutton-Brock T, Van Dijk I, van Kesteren Z, van Tienhoven G, Bel A, van den Aardweg J, Stevens M Tags: Br J Radiol Source Type: research

Comparison of likert and PI-RADS version 2 MRI scoring systems for the detection of clinically significant prostate cancer.
CONCLUSION: Likert and PI-RADS systems both demonstrate high cancer detection rates. Likert scoring had a higher AUC with moderately higher specificity and lower positive call rate and could potentially help to reduce the number of unnecessary biopsies performed. ADVANCES IN KNOWLEDGE: This paper illustrates that the Likert scoring system has potential to help urologists reduce the number of prostate biopsies performed. PMID: 32479105 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - June 1, 2020 Category: Radiology Authors: Zawaideh JP, Sala E, Pantelidou M, Shaida N, Koo B, Caglic I, Warren AY, Carmisciano L, Saeb-Parsy K, Gnanapragasam VJ, Kastner C, Barrett T Tags: Br J Radiol Source Type: research

Differential diagnosis of < 3 cm renal tumorsby ultrasonography: A rapid, Quantitative, Elastography Self-corrected Contrast-enhanced Ultrasound Imaging Mode beyond Screening.
Differential diagnosis of
Source: The British Journal of Radiology - June 1, 2020 Category: Radiology Authors: Sun D, Lu Q, Wei C, Li Y, Zheng Y, Hu B Tags: Br J Radiol Source Type: research

Emerging strategies to target cancer metabolism and improve radiation therapy outcomes.
Abstract Cancer-specific metabolic changes support the anabolic needs of the rapidly growing tumor, maintain a favorable redox balance and help cells adapt to microenvironmental stresses like hypoxia and nutrient deprivation. Radiation is extensively applied in a large number of cancer treatment protocols but despite its curative potential, radiation resistance and treatment failures pose a serious problem. Metabolic control of DNA integrity and genomic stability can occur through multiple processes, encompassing cell cycle regulation, nucleotide synthesis, epigenetic regulation of gene activity and antioxidant de...
Source: The British Journal of Radiology - May 28, 2020 Category: Radiology Authors: Kery M, Papandreou I Tags: Br J Radiol Source Type: research

Application of monoexponential, Biexponential, and Stretched-exponential Models of Diffusion-weighted Magnetic Resonance Imaging in the Differential Diagnosis of Metastases and Myeloma in the Spine.
CONCLUSION: The 3 models of DWI have certain values indifferentiating metastases and myeloma in spine, and the diagnostic performance of ADC, D, α and D*was better. Combining ADC with α may markedly aid in the differential diagnosis of the two. ADVANCES IN KNOWLEDGE: Monoexponential, biexponential, and stretched-exponential models can offer additional information in the differential diagnosis of metastases and myeloma in the spine. Decision tree model and logistic regression model are effective methods to help further distinguish the two. PMID: 32462885 [PubMed - as supplied by publisher] (Source: The...
Source: The British Journal of Radiology - May 28, 2020 Category: Radiology Authors: Xing YX, Zhang HJ, Chen YY, Zhao Q, Lang N, Yuan SH Tags: Br J Radiol Source Type: research

A comparison of manually populated radiology information systemdigital radiographic datawith electronic dose management systems.
CONCLUSIONS: The RIS data poorly represented the DMS data. ADVANCES IN KNOWLEDGE: RIS KAP data are a poor surrogate for DMS data in DR RIS data should only be used in patient dose surveys with an understanding of its limitations and potential inaccuracies. PMID: 32462887 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - May 28, 2020 Category: Radiology Authors: Dickinson N, Dunn M Tags: Br J Radiol Source Type: research

High prevalence of peribronchial focal lesions of airway invasive aspergillosis in haematological cancer patients with prolonged neutropenia.
CONCLUSIONS: Peribronchial focal lesions are a common finding in early-IPA whatever the GM value during neutropenia and our findings reinforce the efficiency of a preemptive approach. ADVANCES IN KNOWLEDGE;: Peribronchial focal lesions, which are classically described in airway invasive aspergillosis, are a common finding in early-IPA in haematological cancer patients with prolonged neutropenia regardless of the GM value, and such peribronchial lesions should reinforce the possibility of IPA. PMID: 32462888 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - May 28, 2020 Category: Radiology Authors: Casutt A, Couchepin J, Brunel AS, Lovis A, Bochud PY, Keller N, Lamoth F, Beigelman-Aubry C Tags: Br J Radiol Source Type: research

Patterns of enhancement in the hepatobiliary phase of gadoxetic acid-enhanced MR imaging.
Abstract A variety of patterns of enhancement of liver lesions and liver parenchyma is observed in the hepatobiliary phase (HBP) of gadoxetic acid-enhanced MR imaging. It is becoming increasingly apparent that many lesions may exhibit HBP enhancement. Much of the literature regarding the role of gadoxetic acid-enhanced MRI in characterising liver lesions is dichotomous, focusing on whether lesions are enhancing or non-enhancing in the HBP, rather than examining the patterns of enhancement. We provide a pattern-based description of HBP enhancement of liver parenchyma and of liver lesions. The role of OATP1B3 transp...
Source: The British Journal of Radiology - May 28, 2020 Category: Radiology Authors: Hui CL, Mautone M Tags: Br J Radiol Source Type: research

Radiobiologically-derived bi-phasic fractionation schemes to overcome the effects of tumour hypoxia.
CONCLUSION: In hypoxic tumours, novel fractionation strategies result in significantly higher tumour BED in comparison to conventional fractionation. ADVANCES IN KNOWLEDGE: We demonstrate that novel bi-phasic fractionation regimens could overcome the effects of tumour hypoxia resulting in biological dose escalation. PMID: 32462907 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - May 28, 2020 Category: Radiology Authors: Joseph N, Kirkby NF, Hoskin PJ, West CML, Choudhury A, Dale RG Tags: Br J Radiol Source Type: research

BioXmark ® liquid fiducial markers for image guided radiotherapy in muscle invasive bladder cancer, a safety and performance trial.
CONCLUSION: The success rate of this novel fiducial marker was 79% which is above the prospectively defined threshold rate. A distinct learning curve of the injection of the liquid marker was seen over the study period. The marker showed sustained visibility and positional stability during treatment phases and also appears to be safe and easy to inject. ADVANCES IN KNOWLEDGE: This novel liquid BioXmark® marker seem to be a very promising tool in daily-adaptive IGRT for bladder preserving chemo-radiotherapy in muscle invasive bladder cancer. PMID: 32463291 [PubMed - as supplied by publisher] (Source: The Briti...
Source: The British Journal of Radiology - May 28, 2020 Category: Radiology Authors: de Ridder M, Gerbrandy LC, de Reijke TM, Hinnen KA, Hulshof MCCM Tags: Br J Radiol Source Type: research

Undergraduate medical education: a national survey of consultant radiologists.
CONCLUSION: This is the first national survey to assess the current role of Radiologists in teaching medical students. While most are teaching or want to teach, there is a large drop-off between current Scottish and previously reported UK median teaching hours. Engagement from Universities, Royal College of Radiologists and Health Boards is urgently needed to reverse this trend. ADVANCES IN KNOWLEDGE: This is the first national survey into the current role of Radiologists in undergraduate medical education. There is a large drop-off between current Scottish and previously reported UK median teaching hours. PMID: ...
Source: The British Journal of Radiology - May 28, 2020 Category: Radiology Authors: Chew C, O'Dwyer PJ Tags: Br J Radiol Source Type: research

Focal nodular marrow Hyperplasia: Imaging features of 53 cases.
We describe and clarify the imaging characteristics of FNMH on MRI, including chemical shift imaging, CT and various nuclear medicine modalities. An imaging algorithm is suggested for allowing a non-invasive diagnosis. PMID: 32463293 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - May 28, 2020 Category: Radiology Authors: Rajakulasingam R, Saifuddin DA Tags: Br J Radiol Source Type: research

Does Contrast-Enhanced ultrasound (CEUS) play a better role in diagnosis of Breast Lesions with Calcification? A comparison with MRI.
Abstract OBJECTIVES: To compare the efficacy of contrast-enhanced ultrasound enabled reclassification of Breast Imaging Reporting and Data System (CEUS-BI-RADS) with magnetic resonance imaging (MRI) in the diagnosis of breast lesions with calcification. METHODS: A total of 52 breast lesions with calcification from 51 patients were detected by ultrasound (US) as hyperechoic foci and categorized as BI-RADS 3-5. The 51 patients further underwent CEUS scan and MRI. The US-BI-RADS combined with CEUS 5-point score system redefined the classification of BI-RADS which was called CEUS-BI-RADS. The diagnostic efficacy ...
Source: The British Journal of Radiology - May 28, 2020 Category: Radiology Authors: Pan J, Tong W, Luo J, Liang J, Pan F, Zheng Y, Xie YX, Xie X Tags: Br J Radiol Source Type: research

Safety and efficacy of endovascular implantation of a portal vein stent combined with iodine-125 seed-strips followed by transcatheter arterial chemoembolization with Sorafenib for the treatment of hepatocellular carcinoma with portal vein tumor thrombosis.
CONCLUSIONS: PVS-125I-TACE-S is safe for patients with HCC with PVTT and may extend the TTP and survival of patients with Vp4 PVTT. ADVANCES IN KNOWLEDGE: PVS implantation promptly restored flow in the obstructed portal vein, which can reduce the risk of hepatic failure and upper gastrointestinal bleeding. Implantation of iodine-125 seed-strips may directly expose the portal tumor thrombus to radiation and kill cancer cells. Their combined use with TACE-S has a strong scientific rationale. PMID: 32464068 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - May 28, 2020 Category: Radiology Authors: Li S, Li L, Li B, Wang W Tags: Br J Radiol Source Type: research

A simple model for calculatingrelative biological effectiveness of x-rays and gamma radiation in cell survival.
CONCLUSIONS: By combining an innovative method for calculating [Formula: see text] with a microdosimetric model, we developed a model that is consistent with extensive experimental data involving photon energies from 0.27 keV to 1.25 MeV. ADVANCES IN KNOWLEDGE: We have developed a photon RBE model applicable to an energy range from ultra-soft x-rays to megaelectron volt γ radiation, including high dose levels where the RBE cannot be calculated as the ratio of α values. In this model, the ionization density represented by [Formula: see text] determines the RBE for a given photon spectrum. PMID: 3246408...
Source: The British Journal of Radiology - May 28, 2020 Category: Radiology Authors: Vassiliev ON, Peterson CB, Grosshans DR, Mohan R Tags: Br J Radiol Source Type: research

Fascia lata attachment at the iliac crest: refining our diagnostic criteria of injury on magnetic resonance imaging.
The objective of this study was to determine the prevalence and spectrum of pathology of the fascia lata attachment at the iliac crest (FLAIC) on MRI in asymptomatic patients in order to refine our diagnostic criteria for clinically relevant FLAIC injury. METHODS AND MATERIAL: Two readers retrospectively evaluated the FLAIC on each side on coronal large field-of-view short tau inversion recovery images on 100 musculoskeletal pelvic MRI exams performed in patients without hip pain (total n = 200). Pathology of the FLAIC was graded using a 3-point Likert scale and discrepancies were resolved by consensus. RESULTS: ...
Source: The British Journal of Radiology - May 27, 2020 Category: Radiology Authors: Serhal A, Adams B, Omar I, Deshmukh S Tags: Br J Radiol Source Type: research

It is time to think inside the (collimation) box; a quality improvement project to reduce over-scanning in CT scanning of the kidneys, ureters and bladder.
CONCLUSION: This DGH was over scanning a large proportion of patients. Manually stopping the CTKUB significantly reduced over scanning. ADVANCES IN KNOWLEDGE: A small change to CTKUB scanning technique can significantly improve adherence to RCR guidelines. PMID: 32459517 [PubMed - as supplied by publisher] (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - May 27, 2020 Category: Radiology Authors: Netke T, Spurr M, Vosough A Tags: Br J Radiol Source Type: research