Long-Term Patient-Reported Dyspareunia After Definitive Chemoradiation for Anal Cancer: Using the Anterior Vaginal Wall as an Organ-at-Risk to Define an Actionable Dosimetric Goal

CONCLUSIONS: Increased dose to the vaginal canal is significantly associated with worse patient-reported dyspareunia following CRT for SCCA. Minimizing dose to the AVW to V35 Gy < 60% may reduce the risk of this quality of life-limiting toxicity. Further prospective evaluation is needed to validate these findings.PMID:38550361 | PMC:PMC10966171 | DOI:10.1016/j.adro.2024.101449

Source: Adv Data - March 29, 2024 Category: Epidemiology Authors: Michael K Rooney Joshua S Niedzielski Ramon M Salazar Angelica Arzola Prajnan Das Eugene J Koay Albert Koong Ethan B Ludmir Bruce D Minsky Sonal Noticewala Grace L Smith Cullen Taniguchi Emma B Holliday Source Type: research