Study of PRESAGE ® dosimeter for end-to-end 3D radiotherapy verification using an anthropomorphic phantom with bespoke dosimeter insert
This study proves the capability of PRESAGE® and bespoke MAX-HD phantom in conjunction with the 3DmicroHD-OCT system to measure 3D dose distribution for end-to-end dosimetry verification.PMID:38634981 | DOI:10.1007/s13246-024-01418-9 (Source: Health Physics)
Source: Health Physics - April 18, 2024 Category: Physics Authors: Muhammad Zamir Mohyedin Hafiz Mohd Zin Auwal Abubakar Ahmad Taufek Abdul Rahman Source Type: research

The incidence of osteoradionecrosis of the jaws in oral cavity cancer patients treated with intensity-modulated radiotherapy: A systematic review and meta-analysis
A systematic review with meta-analysis was conducted to define the incidence of osteoradionecrosis (ORN) in patients with oral cavity cancer (OCC) treated with intensity-modulated radiotherapy (IMRT), and to identify the risk factors influencing its development. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - April 18, 2024 Category: ENT & OMF Authors: Luis Augusto de Almeida-Silva, Juliana dos Santos Lupp, Leonardo Alvares Sobral-Silva, Luiz Augusto Rodrigues dos Santos, Thays Oliveira Marques, Danillo Babinskas Ribeiro da Silva, Taciana Marco Ferraz Caneppele, Michelle Bianchi-de-Moraes Source Type: research

Study of PRESAGE ® dosimeter for end-to-end 3D radiotherapy verification using an anthropomorphic phantom with bespoke dosimeter insert
This study proves the capability of PRESAGE® and bespoke MAX-HD phantom in conjunction with the 3Dmicro HD-OCT system to measure 3D dose distribution for end-to-end dosimetry verification. (Source: Australasian Physical and Engineering Sciences in Medicine)
Source: Australasian Physical and Engineering Sciences in Medicine - April 18, 2024 Category: Biomedical Engineering Source Type: research

A Japanese multi-institutional phase II study of moderate hypofractionated intensity-modulated radiotherapy with image-guided technique for prostate cancer
CONCLUSION: The safety and efficacy of moderately hypofractionated IMRT with prostate-based image-guidance was confirmed among Japanese patients with prostate cancer.PMID:38630382 | DOI:10.1007/s10147-024-02517-z (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - April 17, 2024 Category: Cancer & Oncology Authors: Katsumasa Nakamura Keiji Nihei Yoshihiro Saito Naoto Shikama Shin-Ei Noda Ryusuke Hara Toshiyuki Imagumbai Takashi Mizowaki Takeshi Akiba Etsuo Kunieda Masanori Someya Saiji Ohga Jiro Kawamori Takuyo Kozuka Yosuke Ota Koji Inaba Takeshi Kodaira Yoshiyuki Source Type: research

Incorporating functional lung imaging (FLI) into radiation therapy planning in patients with lung cancer: A systematic review and meta-analysis
CONCLUSIONS: FLI shows promise as a method to spare FL during thoracic RT, but interventional trials related to FL avoidance planning are sparse. Such trials are critical to understanding the impact of FL avoidance planning on toxicity reduction and patient outcomes.PMID:38631538 | DOI:10.1016/j.ijrobp.2024.04.001 (Source: Health Physics)
Source: Health Physics - April 17, 2024 Category: Physics Authors: Julie Midroni Rohan Salunkhe Zhihui Liu Ronald Chow Gabriel Boldt David Palma Douglas Hoover Yevgeniy Vinogradskiy Srinivas Raman Source Type: research

A Japanese multi-institutional phase II study of moderate hypofractionated intensity-modulated radiotherapy with image-guided technique for prostate cancer
ConclusionThe safety and efficacy of moderately hypofractionated IMRT with prostate-based image-guidance was confirmed among Japanese patients with prostate cancer. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - April 17, 2024 Category: Cancer & Oncology Source Type: research

Using the genomic adjusted radiation dose (GARD) to personalize the radiation dose in nasopharyngeal cancer
Radiotherapy (RT) is an integral component of nasopharyngeal cancer (NPC) management. Advanced RT techniques such as intensity-modulated radiotherapy (IMRT) have improved the anatomical precision of local treatment for primary NPC.[1] Despite this, around 20 –30 % of patients develop local recurrence and/or distant metastases.[2] Additionally, up to 50 % of patients in remission experience RT-induced late toxicities.[3] Current radiation dose protocols are uniformly standardized at 66–70 Gy for gross disease and 54–60 Gy for elective nodal regions, despite substantial heterogeneity in treatment response. (Sou...
Source: Radiotherapy and Oncology - April 16, 2024 Category: Radiology Authors: Chi Leung Chiang, Kenneth Sik Kwan Chan, Huaping Li, Wai Tong Ng, James Chung Hang Chow, Horace Cheuk Wai Choi, Ka On Lam, Victor Ho Fun Lee, Roger Kai Cheong Ngan, Anne Wing Mui Lee, Steven A Eschrich, Javier F Torres-Roca, Jason Wing Hon Wong Tags: Original Article Source Type: research

Comparison of 3-year local control using DAHANCA radiotherapy guidelines before and after implementation of five millimetres geometrical GTV to high-dose CTV margin
Primary radiotherapy is the preferred anatomy-preserving treatment for squamous cell carcinomas in the head and neck region (HNSCC), excluding carcinomas in the oral cavity or certain localised oropharyngeal/laryngeal cancers amenable to surgery[1,2]. Platinum-based chemo-radiotherapy (CRT) using IMRT/VMAT techniques is the contemporary standard for loco-regionally advanced HNSCC, with a five-year risk of local and regional failures of 23.5  % and 20.2 %, respectively, using altered fractionation regimes [3]. (Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - April 16, 2024 Category: Radiology Authors: Ruta Zukauskaite Ruta, Morten Horsholt Kristensen, Jesper Grau Eriksen, J ørgen Johansen, Eva Samsøe, Lars Johnsen, Camilla Kjær Lønkvist, Cai Grau, Christian Rønn Hansen Tags: Original Article Source Type: research

Clinical-radiomics nomogram for the risk prediction of esophageal fistula in patients with esophageal squamous cell carcinoma treated with intensity-modulated radiation therapy or volumetric-modulated arc therapy
CONCLUSIONS: The clinical-radiomics nomogram can predict the risk of EF in ESCC patients and is helpful for the individualized treatment of EC.PMID:38617757 | PMC:PMC11009608 | DOI:10.21037/jtd-24-191 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Zhaohui Li Jie Gong Liu Shi Jie Li Zhi Yang Guangjin Chai Bo Lv Geng Xiang Bin Wang Shamus R Carr Alfonso Fiorelli Mei Shi Yilin Zhao Lina Zhao Source Type: research

Postoperative radiotherapy results in 192 epithelial thymic tumours patients with 10  years of follow-up
CONCLUSION: Approximately one-third of the TET in our study experienced a LRR, mainly to the pleura, and 8% in total were in-field. The place of radiotherapy should be better defined in higher risk thymoma patients within prospective randomized studies.PMID:38614283 | DOI:10.1016/j.radonc.2024.110272 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Hugo Lopez Angela Botticella Farid Belkhir Benjamin Besse Elie Fadel Olaf Mercier Antonin Levy C écile Le Péchoux Source Type: research

Postoperative radiotherapy results in 192 epithelial thymic tumours patients with 10  years of follow-up
CONCLUSION: Approximately one-third of the TET in our study experienced a LRR, mainly to the pleura, and 8% in total were in-field. The place of radiotherapy should be better defined in higher risk thymoma patients within prospective randomized studies.PMID:38614283 | DOI:10.1016/j.radonc.2024.110272 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Hugo Lopez Angela Botticella Farid Belkhir Benjamin Besse Elie Fadel Olaf Mercier Antonin Levy C écile Le Péchoux Source Type: research

Observations of the effectiveness, dosage, and prognosis of intensity-modulated radiation therapy under ultrasonic guidance for cervical cancer patients
CONCLUSION: VMAT guided by ultrasound for patients with cervical cancer demonstrates promising short- and long-term treatment outcomes. It also leads to improvements in serum CEA, SCC-Ag, and CA724 levels, as well as reductions in the average radiation dosages to the radiotherapy target area, rectum, and bladder. This approach warrants attention from clinicians in clinical practice.PMID:38607778 | DOI:10.3233/THC-231977 (Source: Technology and Health Care)
Source: Technology and Health Care - April 12, 2024 Category: Medical Devices Authors: Chenxi Li Jian Li Yao Lu Jiahui Hou Zhaoyu Zhi Baocun Zhao Xiumei Zhang Source Type: research

Observations of the effectiveness, dosage, and prognosis of intensity-modulated radiation therapy under ultrasonic guidance for cervical cancer patients
CONCLUSION: VMAT guided by ultrasound for patients with cervical cancer demonstrates promising short- and long-term treatment outcomes. It also leads to improvements in serum CEA, SCC-Ag, and CA724 levels, as well as reductions in the average radiation dosages to the radiotherapy target area, rectum, and bladder. This approach warrants attention from clinicians in clinical practice.PMID:38607778 | DOI:10.3233/THC-231977 (Source: Technology and Health Care)
Source: Technology and Health Care - April 12, 2024 Category: Medical Devices Authors: Chenxi Li Jian Li Yao Lu Jiahui Hou Zhaoyu Zhi Baocun Zhao Xiumei Zhang Source Type: research

Observations of the effectiveness, dosage, and prognosis of intensity-modulated radiation therapy under ultrasonic guidance for cervical cancer patients
CONCLUSION: VMAT guided by ultrasound for patients with cervical cancer demonstrates promising short- and long-term treatment outcomes. It also leads to improvements in serum CEA, SCC-Ag, and CA724 levels, as well as reductions in the average radiation dosages to the radiotherapy target area, rectum, and bladder. This approach warrants attention from clinicians in clinical practice.PMID:38607778 | DOI:10.3233/THC-231977 (Source: Technology and Health Care)
Source: Technology and Health Care - April 12, 2024 Category: Medical Devices Authors: Chenxi Li Jian Li Yao Lu Jiahui Hou Zhaoyu Zhi Baocun Zhao Xiumei Zhang Source Type: research