Brachytherapy: Understanding the past to guide future practice
“Study the past if you want to define the future” -Confucius (Source: Brachytherapy)
Source: Brachytherapy - April 15, 2021 Category: Cancer & Oncology Authors: Amandeep S. Taggar, Daniel Taussky Source Type: research

Effects of 3D image-guided brachytherapy compared to 2D conventional brachytherapy on clinical outcomes in patients with cervical cancer: A systematic review and meta-analyses
To assess the effects of three-dimensional image-guided brachytherapy (3D BT) compared to bi-dimensional BT (2D BT) on clinical outcomes in patients with cervical cancer. (Source: Brachytherapy)
Source: Brachytherapy - April 15, 2021 Category: Cancer & Oncology Authors: Erica Aranha Suzumura, Layse Martins Gama, Beate Jahn, Alessandro Gon çalves Campolina, Heloisa de Andrade Carvalho, Patrícia Coelho de Soárez Source Type: research

Comparison between postoperative TRUS-CT fusion with MRI-CT fusion for postimplant quality assurance in prostate LDR permanent seed brachytherapy
PURPOSE/OBJECTIVE Permanent seed Low-Dose-Rate brachytherapy is planned and delivered using transrectal ultrasound (TRUS). Post-implant evaluation for quality assurance is usually performed using Computed Tomography (CT). Registration of the CT images with MRI reduces subjectivity in contouring by improving prostate edge detection. We hypothesized that a set of TRUS images post procedure may provide the same benefit.MATERIAL/METHODS Consecutive patients undergoing Low-Dose-Rate prostate brachytherapy were recruited. (Source: Brachytherapy)
Source: Brachytherapy - April 15, 2021 Category: Cancer & Oncology Authors: Steven Tisseverasinghe, Marina Marb án, Juanita Crook, David Petrik, Cynthia Araujo Source Type: research

Patient-controlled epidural analgesia, patient-controlled intravenous analgesia, and conventional intravenous opioids for gynecologic interstitial brachytherapy: A single-center retrospective study
PURPOSE Interstitial brachytherapy for gynecologic malignancies is stressful physically and mentally; however, optimal analgesic methods remain unclear. We investigated the effect of analgesic methods on pain and adverse events during interstitial brachytherapy for gynecologic malignancies.METHODS The data of 73 patients who underwent interstitial brachytherapy for gynecologic malignancies between April 2015 and March 2020 were retrospectively analyzed. Patient-controlled epidural analgesia (PCEA), patient-controlled intravenous analgesia (PCIA), and conventional intravenous opioid administration were used for analgesia du...
Source: Brachytherapy - April 15, 2021 Category: Cancer & Oncology Authors: Yuya Murata, Kumiko Yamada, Yuto Hamaguchi, Tomohiro Ohigashi, Kazushi Maruo, Soichiro Yamashita, Makoto Tanaka Source Type: research

Prospective randomized trial of email and/or telephone reminders to enhance vaginal dilator compliance in patients undergoing brachytherapy for gynecologic malignancies
To evaluate whether email survey +/- telephone reminder versus no intervention would facilitate compliance with vaginal dilator use in women undergoing brachytherapy for gynecologic malignancies and to assess changes in vaginal canal (VC) length between the groups. (Source: Brachytherapy)
Source: Brachytherapy - April 15, 2021 Category: Cancer & Oncology Authors: Margaret M. Kozak, Melissa Usoz, Dylann Fujimoto, Rie von Eyben, Elizabeth Kidd Source Type: research

Radioactive and normal stent insertion for the treatment of malignant airway stenosis: A meta-analysis
To demonstrate the advantage of radioactive stent (RS) for treating malignant airway stenosis (MAS) in reducing the stent restenosis rate and increasing overall survival (OS). (Source: Brachytherapy)
Source: Brachytherapy - April 13, 2021 Category: Cancer & Oncology Authors: Qing-Kun Meng, Xiao-Ying Yu, Wei Li, Qing-Lan Sun Tags: Review Article Source Type: research

Quantifying risk using FMEA: An alternate approach to AAPM TG-100 for scoring failures and evaluating clinical workflow
Renovation of the brachytherapy program at a leading cancer center utilized methods of the AAPM TG-100 report to objectively evaluate current clinical brachytherapy workflows and develop techniques for minimizing the risk of failures, increasing efficiency, and consequently providing opportunities for improved treatment quality. The TG-100 report guides evaluation of clinical workflows with recommendations for identifying potential failure modes (FM) and scoring them from the perspective of their occurrence frequency O, failure severity S, and inability to detect them D. (Source: Brachytherapy)
Source: Brachytherapy - April 8, 2021 Category: Cancer & Oncology Authors: Sean A. Roles, Jaroslaw T. Hepel, Kara L. Leonard, David E. Wazer, Gene A. Cardarelli, Michelle L. Schwer, Ziad H. Saleh, Eric E. Klein, James M. Brindle, Mark J. Rivard Source Type: research

Live implant dosimetry may be an effective replacement for postimplant computed tomography in localized prostate cancer patients receiving low dose rate brachytherapy
To determine if Live Implant Dosimetry (LIDO) utilizing intraoperative transrectal ultrasound (TRUS) is equivalent to postimplant CT dosimetry (either day 0 or day 30) in patients with localized prostate cancer (PC) treated with low dose rate (LDR) prostate seed brachytherapy. (Source: Brachytherapy)
Source: Brachytherapy - April 8, 2021 Category: Cancer & Oncology Authors: Davood Roshan, Kieran Joyce, Peter Woulfe, Pradeep Reddy Gorakati, Richard Stock, Francis J. Sullivan Source Type: research

ACR –ABS–ACNM–ASTRO–SIR–SNMMI practice parameter for selective internal radiation therapy or radioembolization for treatment of liver malignancies
The American College of Radiology (ACR), American Brachytherapy Society (ABS), American College of Nuclear Medicine (ACNM), American Society for Radiation Oncology (ASTRO), Society of Interventional Radiology (SIR), and Society of Nuclear Medicine and Molecular Imaging (SNMMI) have jointly developed a practice parameter on selective internal radiation therapy (SIRT) or radioembolization for treatment of liver malignancies. Radioembolization is the embolization of the hepatic arterial supply of hepatic primary tumors or metastases with a microsphere yttrium-90 brachytherapy device. (Source: Brachytherapy)
Source: Brachytherapy - April 3, 2021 Category: Cancer & Oncology Authors: Kelvin Hong, Olaguoke Akinwande, Lisa Bodei, Murthy RK. Chamarthy, Phillip M. Devlin, Shana Elman, Suvranu Ganguli, Andrew S. Kennedy, Sonya J. Koo, Zoubir Ouhib, Siddharth A. Padia, Riad Salem, Reed G. Selwyn, Catheryn M. Yashar, Don C. Yoo, Bassem I. Za Source Type: research

Virtual reality-based simulation improves gynecologic brachytherapy proficiency, engagement, and trainee self-confidence
Intracavitary brachytherapy is critical in treatment of cervical cancer with the highest rates of local control and survival. Only about 50% of graduating residents express confidence to develop a brachytherapy practice with caseload as the greatest barrier. We hypothesize that virtual reality (VR)-based intracavitary brachytherapy simulation will improve resident confidence, engagement, and proficiency. (Source: Brachytherapy)
Source: Brachytherapy - April 3, 2021 Category: Cancer & Oncology Authors: Neil K. Taunk, Nishant K. Shah, Emily Hubley, Shibu Anamalayil, Jacob W. Trotter, Taoran Li Source Type: research

Five-year results of accelerated partial breast irradiation: A single-institution retrospective review of 289 cases
We report 5-year survival outcomes, cosmesis, and treatment-related toxicity. (Source: Brachytherapy)
Source: Brachytherapy - March 30, 2021 Category: Cancer & Oncology Authors: Maria Laplana, Salvatore Cozzi, Dina Najjari, Marta Irene Mart ín, Gerard Rodríguez, Andrea Slocker, Ismael Sancho, Maria Jesús Pla, Marc García, Ruth Gracia, Joan Pera, Ferran Guedea, Cristina Gutiérrez Source Type: research

Interstitial brachytherapy for gynecologic malignancies: Complications, toxicities, and management
From both a disease and management perspective, locally advanced gynecologic cancers present a significant challenge. Dose escalation with brachytherapy serves as a key treatment, providing conformal radiation while sparing at-risk organs. Intracavitary brachytherapy techniques have been shown to be effective, with improving tumor control and toxicity profiles with the advent of three-dimensional image planning. Despite this, the variations in tumor size, location, and pelvic anatomy may lead to suboptimal dosimetry with standard intracavitary applicators in some clinical scenarios. (Source: Brachytherapy)
Source: Brachytherapy - March 29, 2021 Category: Cancer & Oncology Authors: Mitchell Kamrava, Saad Maili Alrashidi, Eric Leung Source Type: research

Tumor control and cosmetic outcome of weekly iridium-192 high-dose-rate brachytherapy for nonmelanoma skin cancers in the elderly
Radiotherapy with high-dose-rate (HDR) brachytherapy is used to treat nonmelanoma skin cancers. We retrospectively analyzed a hypofractionated regimen to assess its safety and efficacy in elderly patients ≥70 years. (Source: Brachytherapy)
Source: Brachytherapy - March 28, 2021 Category: Cancer & Oncology Authors: John Roberson, Rushil Patel, Jordan B. Slutsky, Samuel Ryu, Zhigang Xu, Edward Valentine Source Type: research

A multipurpose brachytherapy catheter to enable intratumoral injection
To create and test a multipurpose brachytherapy catheter prototype enabling intratumoral injection and brachytherapy after a single catheter insertion. (Source: Brachytherapy)
Source: Brachytherapy - March 27, 2021 Category: Cancer & Oncology Authors: Justin C. Jagodinsky, Gabriella Medeiros, Hayley H. Raj, Amira Razuan, Alexis Locsin, Tirhas G. Dempsey, Beixiao Tang, Ishan Chakravarty, Paul A. Clark, Raghava N. Sriramaneni, Won Jong Jin, Keng-Hsueh Lan, Rupak K. Das, Jessica R. Miller, Darilis Suarez- Source Type: research

MRI and dual-energy CT fusion anatomic imaging in Ru-106 ophthalmic brachytherapy
This study examines the possibility of creating fusion images from MRI scans (preoperatively) and DECT scans (with the plaque in place) as a tool for confirming the anatomic accuracy of plaque placement. (Source: Brachytherapy)
Source: Brachytherapy - March 27, 2021 Category: Cancer & Oncology Authors: Efstathios T. Detorakis, Kostas Perisinakis, Eleni Drakonaki, Dimitrios Liakopoulos, Antonios Tzedakis, Efrosini Papadaki, Miltiadis K. Tsilimbaris Source Type: research

MRI-guided brachytherapy for locally advanced cervical cancer: Program initiation, learning curve and dose delivery results in Kuopio University Hospital
Image guided adaptive brachytherapy, the standard treatment for locally advanced cervical cancer (LACC), is a complex medical procedure that requires an experienced multidisciplinary team. The aims of this analysis were to assess (1) the learning curve of brachytherapy team, (2) dose-volume parameters, (3) the use of an interstitial component, and (4) the overall treatment time (OTT). (Source: Brachytherapy)
Source: Brachytherapy - March 26, 2021 Category: Cancer & Oncology Authors: Ester J ääskeläinen, Henna Kärkkäinen, Jan-Erik Palmgren, Tommi Tolmunen, Siiri-Liisi Kraav, Maarit Anttila Source Type: research

Role of brachytherapy in stage III endometrial cancer treated with adjuvant chemotherapy: Identifying factors predictive of a survival benefit
To determine which patients with stage III endometrial cancer receiving adjuvant chemotherapy derive benefit from the addition of vaginal brachytherapy, as stage III is a highly heterogeneous population with substantial variations in practice. (Source: Brachytherapy)
Source: Brachytherapy - March 26, 2021 Category: Cancer & Oncology Authors: Michael Xiang, Diana P. English, Elizabeth A. Kidd Source Type: research

Uterine perforation during brachytherapy for cervical cancer: Complications, outcomes, and best practices for forward treatment planning and management
The purpose of the study was to determine the incidence of uterine perforations, review the associated complications, and propose guidelines for management of perforations after brachytherapy. (Source: Brachytherapy)
Source: Brachytherapy - March 17, 2021 Category: Cancer & Oncology Authors: William Small, Yo Sup Kim, Cara Joyce, Murat Surucu, Mark Leshyk, Matthew M. Harkenrider, Ronald K. Potkul, Margaret Liotta, Abigail Winder, Basel Altoos Source Type: research

Vaginal dose-surface maps in cervical cancer brachytherapy: Methodology and preliminary results on correlation with morbidity
The purpose of the study was to develop a methodology for vaginal dose-surface maps (DSMs) in patients with cervix cancer and to investigate dose-surface histogram metrics as predictors for vaginal stenosis (St) and mucositis (Muc). (Source: Brachytherapy)
Source: Brachytherapy - March 17, 2021 Category: Cancer & Oncology Authors: Monica Serban, Astrid A.C. de Leeuw, Kari Tanderup, Ina M. J ürgenliemk-Schulz Source Type: research

Ultra-long-term toxicity of prostate brachytherapy
The true long-term toxicity associated with most radiation treatments is unknown. Prostate cancer patients survive decades after prostate cancer brachytherapy, with unclear long-term toxicity profiles. We therefore evaluated prostate cancer patients who had received I-125 brachytherapy treatment (14,400  cGy) 14–24 years prior and assessed their long-term quality of life based on urinary, bowel, and sexual function. (Source: Brachytherapy)
Source: Brachytherapy - March 6, 2021 Category: Cancer & Oncology Authors: Elizabeth Thompson, William Barrett Source Type: research

High-dose-rate brachytherapy for facial skin cancer: Outcome and toxicity assessment for 71 cases
In France, the reference technique for skin cancer was low-dose-rate brachytherapy (BT) delivered via iridium wire. At the end of their commercialization in 2015 we have replaced them by high-dose-rate (HDR) BT via interstitial catheters. We assessed efficacy and tolerance as soon as this technique was implemented. (Source: Brachytherapy)
Source: Brachytherapy - March 5, 2021 Category: Cancer & Oncology Authors: Sophie Renard, Julia Salleron, Jean-Fran çois Py, Mathilde Cuenin, Isabelle Buchheit, Vincent Marchesi, Sandrine Huger, Emilie Meknaci, Didier Peiffert Source Type: research

A stent with radioactive seed strand insertion for inoperable malignant biliary obstruction: A meta-analysis
The purpose of the study was to assess the relative clinical effectiveness of stent insertion with or without radioactive seed strand (RSS) insertion in patients suffering from malignant biliary obstruction (MBO). (Source: Brachytherapy)
Source: Brachytherapy - March 4, 2021 Category: Cancer & Oncology Authors: Yi-Yang Huang, Xin-Jian Xu, Xiang-Zhong Huang, Hong Cheng Source Type: research

The one hundred most cited publications in prostate brachytherapy
The aim of this study is to identify the leaders in research on prostate brachytherapy through a bibliometric analysis of the top 100 most cited publications in the field. (Source: Brachytherapy)
Source: Brachytherapy - March 2, 2021 Category: Cancer & Oncology Authors: Elisheva Donath, Alexandre Alcaidinho, Guila Delouya, Daniel Taussky Source Type: research

Editorial Board
(Source: Brachytherapy)
Source: Brachytherapy - March 1, 2021 Category: Cancer & Oncology Source Type: research

Masthead
(Source: Brachytherapy)
Source: Brachytherapy - March 1, 2021 Category: Cancer & Oncology Source Type: research

Table of Contents
(Source: Brachytherapy)
Source: Brachytherapy - March 1, 2021 Category: Cancer & Oncology Source Type: research

Reporting of dose –volume specifications for “Martinez Universal Perineal Interstitial Template–based interstitial high-dose-rate brachytherapy for gynecological cancers” according to International Commission on Radiation Units and Measurements 58 with early clinical outcomes
The study is an audit of reporting dose and volume specifications as per the ICRU 58 for MUPIT-based interstitial brachytherapy in gynecological cancers. Correlation between total reference air kerma (TRAK) and isodose surface was also evaluated to understand the intensity of treatment in interstitial brachytherapy. (Source: Brachytherapy)
Source: Brachytherapy - February 26, 2021 Category: Cancer & Oncology Authors: Sahil Sood, Lavanya Gurram, Dheera Aravindakshan, John Paul, Supriya Chopra, Jamema Swamidas, Akshay Patil, Umesh Mahantshetty Source Type: research

A multiobserver study investigating the effectiveness of prostatic multiparametric magnetic resonance imaging to dose escalate corresponding histologic lesions using high-dose-rate brachytherapy
Using multiparametric MRI data and the pathologic data from radical prostatectomy specimens, we simulated the treatment planning of dose-escalated high-dose-rate brachytherapy (HDR-BT) to the Multiparametric MRI dominant intraprostatic lesion (mpMRI-DIL) to compare the dose potentially delivered to the pathologically confirmed locations of the high-grade component of the cancer. (Source: Brachytherapy)
Source: Brachytherapy - February 26, 2021 Category: Cancer & Oncology Authors: Christopher W. Smith, Douglas Hoover, Kathleen Surry, David D'Souza, Derek W. Cool, Zahra Kassam, Matthew Bastian-Jordan, Jose A. Gomez, Madeleine Moussa, Joseph Chin, Stephen Pautler, Glenn S. Bauman, Aaron D. Ward Source Type: research

Multi-institutional registry study evaluating the feasibility and toxicity of accelerated partial breast irradiation using noninvasive image-guided breast brachytherapy
The noninvasive image-guided breast brachytherapy (NIBB) technique is a novel noninvasive yet targeted method for accelerated partial breast irradiation. We established a multi-institutional registry to evaluate the toxicity and efficacy of this technique across various practice settings. (Source: Brachytherapy)
Source: Brachytherapy - February 25, 2021 Category: Cancer & Oncology Authors: Jaroslaw T. Hepel, Kara L. Leonard, Mark Rivard, Rashmi Benda, Ann Pittier, Dean Mastras, Sandra Sha, Leann Smith, Michael Kerley, Paul G. Kocheril, Tushar R. Shah, Andrea McKee, John Chinault, Bushra Rana, David E. Wazer Source Type: research

Complications and side effects of high-dose-rate prostate brachytherapy
To describe technical challenges and complications encountered during and after high-dose-rate prostate brachytherapy (HDR-BT) and review management of these complications. (Source: Brachytherapy)
Source: Brachytherapy - February 18, 2021 Category: Cancer & Oncology Authors: Kevin Martell, Marisa A. Kollmeier Source Type: research

Dosimetric investigation of 103Pd permanent breast seed implant brachytherapy based on Monte Carlo calculations
Permanent breast seed implant using 103Pd is emerging as an effective adjuvant radiation technique for early stage breast cancer. However, clinical dose evaluations follow the water-based TG-43 approach with its considerable approximations. Toward clinical adoption of advanced TG-186 model-based dose evaluations, this study presents a comprehensive investigation for permanent breast seed implant considering both target and normal tissue doses. (Source: Brachytherapy)
Source: Brachytherapy - February 4, 2021 Category: Cancer & Oncology Authors: Stephen G. Deering, Michelle Hilts, Deidre Batchelar, Juanita Crook, Rowan M. Thomson Source Type: research

Comparison of clinical outcomes achieved with image-guided adaptive brachytherapy for cervix cancer using CT or transabdominal ultrasound
This study aimed to evaluate retrospectively the treatment results when using various image-guided adaptive brachytherapy treatments for cervical cancer treated by radical radiotherapy. (Source: Brachytherapy)
Source: Brachytherapy - February 4, 2021 Category: Cancer & Oncology Authors: Ekkasit Tharavichitkul, Pooriwat Muangwong, Somvilai Chakrabandhu, Pitchayaponne Klunklin, Wimrak Onchan, Bongkot Jia-Mahasap, Wannapha Nobnop, Damrongsak Tippanya, Razvan M. Galalae, Imjai Chitapanarux Source Type: research

High-dose-rate interstitial brachytherapy for vaginal endometrial cancer recurrence after prior surgery and radiotherapy
Characterize the clinical outcomes of endometrial cancer vaginal recurrences after previous surgery and radiation therapy treated with reirradiation including image-guided interstitial high-dose-rate (HDR) brachytherapy. (Source: Brachytherapy)
Source: Brachytherapy - February 3, 2021 Category: Cancer & Oncology Authors: Christopher H. Chapman, Adam J. Cunha, Ramey D. Littell, Lee-may Chen, I-Chow Hsu Source Type: research

Brachytherapy of the head and neck: An University of California Los Angeles guide to morbidity reduction
The head and neck (H&N) region is among the most intricate and functional part of our anatomy. Major functional nerves and blood vessels with importance that affect the entire body emanate from the base of skull. Brachytherapy plays an important role as a single modality therapy in early cancer of the lip and oral cavity and a supplemental role in the pharynx or in advanced or recurrent disease. Morbidity in the H&N is intensely personal and disabling. Its avoidance is critical in determining the success or failure of a treatment program, and it is essential to preservation of quality of life. (Source: Brachytherapy)
Source: Brachytherapy - January 21, 2021 Category: Cancer & Oncology Authors: Puja Venkat, James Han, D. Jeffrey Demanes Source Type: research

First clinical implementation of GammaTile permanent brain implants after FDA clearance
GammaTile cesium-131 (131Cs) permanent brain implant has received Food and Drug Administration (FDA) clearance as a promising treatment for certain brain tumors. Our center was the first institution in the United States after FDA clearance to offer the clinical use of GammaTile brachytherapy outside of a clinical trial. The purpose of this work is to aid the medical physicist and radiation oncologist in implementing this collagen carrier tile brachytherapy (CTBT) program in their practice. (Source: Brachytherapy)
Source: Brachytherapy - January 21, 2021 Category: Cancer & Oncology Authors: Clara Ferreira, David Sterling, Margaret Reynolds, Kathryn Dusenbery, Clark Chen, Parham Alaei Source Type: research

Dose fusion and efficacy evaluation of different radical radiotherapy doses for cervical cancer
In this study, 45-Gy and 50.4-Gy treatment groups were compared for fused doses to target tumor areas and organs at risk (OARs), clinical efficacy, and quality of life. (Source: Brachytherapy)
Source: Brachytherapy - January 20, 2021 Category: Cancer & Oncology Authors: Hui Yu, Xi Tang, Xinglong Yang, Danxia Wen, Zhouyu Li, Xiaomin Wen, Jinquan Liu, Mingyi Li Source Type: research

Incidence and dosimetric predictive factors of late rectal toxicity after low-dose-rate brachytherapy combined with volumetric modulated arc therapy in high-risk prostate cancer at a single institution: Retrospective study
The purpose of this study is to investigate the incidence of rectal toxicity and to identify the associated dosimetric predictive parameters after I-125 seed low-dose-rate brachytherapy (LDR-BT) combined with volumetric modulated arc therapy (VMAT) and dose constraints. (Source: Brachytherapy)
Source: Brachytherapy - January 20, 2021 Category: Cancer & Oncology Authors: Takayuki Sakurai, Shigeyuki Takamatsu, Satoshi Shibata, Masashi Taka, Mizuho Ishiyama, Masahiro Yamazaki, Hironori Kojima, Atsushi Mizokami, Tomoyasu Kumano, Toshifumi Gabata Source Type: research

Substantial lymphovascular space invasion predicts worse outcomes in early-stage endometrioid endometrial cancer
Substantial as opposed to focal or no lymphovascular space invasion (LVSI) is proposed as an independent adverse prognostic factor in patients with early-stage endometrioid endometrial cancer (EEC). We reviewed outcomes of patients treated with adjuvant vaginal brachytherapy (VB) alone in a single institution, stratified by LVSI extent. (Source: Brachytherapy)
Source: Brachytherapy - January 20, 2021 Category: Cancer & Oncology Authors: Elizabeth A. Barnes, Kevin Martell, Carlos Parra-Herran, Amandeep S. Taggar, Elysia Donovan, Eric Leung Source Type: research

Complications of intracavitary brachytherapy for gynecologic cancers and their management: A comprehensive review
Intracavitary gynecologic brachytherapy in the form of tandem-based brachytherapy and vaginal cylinder –based brachytherapy represents a fundamental component of the treatment of women with cervical or uterine cancer due to the ability to deliver a therapeutic dose of radiation with sharp dose falloff. This results in highly effective treatment in terms of oncologic outcomes with an overall favorab le toxicity profile. Still, complications and side effects of brachytherapy do exist. While advances in brachytherapy techniques have led to a significant decrease in the rates of toxicity, a thorough understanding of the ...
Source: Brachytherapy - January 19, 2021 Category: Cancer & Oncology Authors: Scott M. Glaser, Pranshu Mohindra, Umesh Mahantshetty, Sushil Beriwal Source Type: research

HDR brachytherapy boost using MR-only workflow for intermediate- and high-risk prostate cancer: 8-year results of a pilot study
To report 8-year clinical outcome with high-dose-rate brachytherapy (HDRBT) boost using MRI-only workflow for intermediate (IR) and high-risk (HR) prostate cancer (PC) patients. (Source: Brachytherapy)
Source: Brachytherapy - January 18, 2021 Category: Cancer & Oncology Authors: Ferenc Lakosi, Gergely Antal, Janos Pall, Andrea Farkas, Tibor Jenei, Denes Nagy, Jozsef Liptak, Istvan Sipocz, Akos Pytel, Melinda Csima, Akos Gulyban, Gabor Toller Source Type: research

HDR brachytherapy as monotherapy for prostate cancer: A systematic review with meta-analysis
The effectiveness and safety of high dose brachytherapy as monotherapy (HDR-BRT-M) in prostate cancer is limited to retrospective studies. We performed a meta-analysis to summarize existing data and identify trends in biochemical recurrence-free survival (bRFS) and toxicity after HDR-BRT-M in patients with prostate cancer. (Source: Brachytherapy)
Source: Brachytherapy - January 15, 2021 Category: Cancer & Oncology Authors: Gustavo Arruda Viani, Caio Viani Arruda, Antonio Cassio Assis Pellizzon, Ligia Issa De Fendi Source Type: research

Dose homogeneity analysis of adjuvant radiation treatment in surgically resected brain metastases: Comparison of IORT, SRS, and IMRT indices
Although surgery remains a treatment option for symptomatic brain metastases, the need for adjuvant radiation after surgery is widely accepted as standard. Despite a multitude of randomized trials aimed at identifying the ideal radiation treatment plan for surgically resected metastases, the development of new delivery regiments necessitates a periodic re-evaluation of dosimetric performance/outcome. Here, we compare the homogeneity index (HI) across three platforms: single-session stereotactic radiosurgery (SRS), multisession stereotactic radiotherapy, and intraoperative radiotherapy (IORT). (Source: Brachytherapy)
Source: Brachytherapy - January 13, 2021 Category: Cancer & Oncology Authors: Basem A. Dahshan, Joshua S. Weir, Robert P. Bice, Paul Renz, Daniel T. Cifarelli, Linda Poplawski, Joshua Hack, John A. Vargo, Christopher P. Cifarelli Source Type: research

Automatic optimization of treatment dosimetry to improve visual outcomes in episcleral plaque brachytherapy
The aim of this study was to develop an automated dose optimization algorithm, powered by simulated annealing, for inverse planning of ocular plaque brachytherapy treatments, to improve tumor coverage and critical structure sparing for reduced treatment-related morbidity. (Source: Brachytherapy)
Source: Brachytherapy - January 8, 2021 Category: Cancer & Oncology Authors: Gawon Han, Matthew Larocque, Ezekiel Weis, Geetha Menon Source Type: research

Editorial Board
(Source: Brachytherapy)
Source: Brachytherapy - January 1, 2021 Category: Cancer & Oncology Source Type: research

Masthead
(Source: Brachytherapy)
Source: Brachytherapy - January 1, 2021 Category: Cancer & Oncology Source Type: research

Table of Contents
(Source: Brachytherapy)
Source: Brachytherapy - January 1, 2021 Category: Cancer & Oncology Source Type: research

Do air gaps with image-guided vaginal cuff brachytherapy impact failure  rates in patients with high-intermediate risk FIGO Stage I endometrial cancer?
The aim of this study was to assess the impact of air gaps at the cylinder surface on the rate of vaginal cuff failure (VCF) after image-guided adjuvant vaginal cuff brachytherapy (VCBT) in the treatment of high-intermediate risk (HIR) FIGO (F édération Internationale de Gynécologie et d'Obstétrique (International Federation of Gynecology and Obstetrics)) Stage I endometrial cancer. (Source: Brachytherapy)
Source: Brachytherapy - December 29, 2020 Category: Cancer & Oncology Authors: Adam H. Richman, Ankur K. Patel, Joshua L. Rodr íguez-López, Andrew Keller, John A. Vargo, Hayeon Kim, Paniti Sukumvanich, Jessica L. Berger, Michelle M. Boisen, Robert Edwards, Sarah E. Taylor, Madeleine B. Courtney-Brooks, Alexander Olawaiye, Brian C. Source Type: research

Letter to the editor regarding “125I seed implantation for hepatocellular carcinoma with portal vein tumor thrombus: A systematic review and metaanalysis”
With interest, we have read the recent paper by Yuan et  al. (1) that was published in Brachytherapy in 2019. They concluded that 125I seed implantation could obtain good local control, improve the survival rate, and reduce the mortality risk and portal venous pressure in hepatocellular carcinoma (HCC) patients with portal vein tumor thrombus (PVTT). Be fore these results can be accepted, we have serious concerns about their use of the HR to estimate pooled survival rate and their study selection. (Source: Brachytherapy)
Source: Brachytherapy - December 26, 2020 Category: Cancer & Oncology Authors: Yingxing Guo, Ting Li, Jingxin Yan Tags: Letter to the Editor Source Type: research

Brachytherapy for lung cancer
Brachytherapy (BT) is a minimally invasive anticancer radiotherapeutic modality where the tumor is directly irradiated via a radioactive source that is precisely implanted in or adjacent to the tumor. BT for lung cancer may be conducted in the form of endobronchial BT and radioactive seed implantation (RSI-BT), mainly for nonsmall cell lung cancer (NSCLC). For patients with early-stage lung cancer who are not suitable for surgery or external beam radiotherapy (EBRT), BT may be used as an alternative treatment, and curative results could be achieved in certain patients with cancer confined to the trachea lumen. (Source: Brachytherapy)
Source: Brachytherapy - December 24, 2020 Category: Cancer & Oncology Authors: Bin Qiu, Ping Jiang, Zhe Ji, Xiaodong Huo, Haitao Sun, Junjie Wang Tags: Review Article Source Type: research

Review of brachytherapy complications – Upper gastrointestinal tract
While brachytherapy applications are not widely used for cancer diagnoses in the upper GI tract (including the esophagus, liver, stomach, and pancreas), they have a clear role in palliation and symptom management and occasionally definitive locoregional treatment. With the increasing use of image-guided techniques, the incidence of side effects and complications has shown to be lower than many other alternative treatment modalities, making brachytherapy approaches a preferred treatment option. This review examines procedural complications and acute and chronic adverse effects from radiation associated with esophageal, hepa...
Source: Brachytherapy - December 22, 2020 Category: Cancer & Oncology Authors: Michael R. Folkert, Sujana Gottumukkala, Nhu Tram Nguyen, Amandeep Taggar, Ranjan Kumar Sur Source Type: research