Initiatives for education, training, and dissemination of morbidity assessment and reporting in a multiinstitutional international context: Insights from the EMBRACE studies on cervical cancer
In 2008, the GEC ESTRO Gyn network launched the first multiinstitutional, observational, and prospective international study on MRI-guided brachytherapy in locally advanced cervical cancer patients (EMBRACE-I). EMBRACE-I was followed by EMBRACE-II from 2016 and ongoing. Among the aims of the EMBRACE studies are to benchmark morbidity outcomes and develop dose-volume effects and predictive models for morbidity. The EMBRACE studies collect both physician (CTCAE v.3) and patient (EORTC QLQ-C30/CX24) reported outcomes, including baseline information, in a regular follow-up schedule. (Source: Brachytherapy)
Source: Brachytherapy - September 22, 2020 Category: Cancer & Oncology Authors: Kathrin Kirchheiner, St éphanie Smet, Sofia Spampinato, Nina B.K. Jensen, Anders Schwartz Vittrup, Lars Fokdal, Dina Najjari-Jamal, Henrike G. Westerveld, Jacob C. Lindegaard, Christian Kirisits, Astrid De Leeuw, Maximilian P. Schmid, Li Tee Tan, Remi A. Source Type: research

Early outcomes after definitive chemoradiation therapy with Vienna/Venezia hybrid high-dose rate brachytherapy applicators for cervical cancer: A  single-institution experience
We report feasibility and early outcomes with the use of these hybrid applicators at our institution. (Source: Brachytherapy)
Source: Brachytherapy - September 17, 2020 Category: Cancer & Oncology Authors: A. Keller, J.L. Rodr íguez-López, A.K. Patel, J.A. Vargo, H. Kim, C.J. Houser, P. Sukumvanich, J.L. Berger, M.M. Boisen, R.P. Edwards, S.E. Taylor, M.B. Courtney-Brooks, B.C. Orr, A.B. Olawaiye, S. Beriwal Source Type: research

Development, implementation, and outcomes of a simulation-based medical education (SBME) prostate brachytherapy workshop for radiation oncology residents
Despite a preponderance of data demonstrating strong clinical outcomes and cost-effectiveness, prostate brachytherapy use and competency continue to decline. Enhanced resident education may help reverse this trend. We therefore developed and implemented a simulation-based medical education course for low-dose-rate prostate brachytherapy (LDR-PB). (Source: Brachytherapy)
Source: Brachytherapy - September 17, 2020 Category: Cancer & Oncology Authors: Shane Mesko, Bhavana V. Chapman, Chad Tang, Rajat J. Kudchadker, Teresa L. Bruno, Jeremiah Sanders, Prajnan Das, Chelsea C. Pinnix, Nikhil G. Thaker, Steven J. Frank Source Type: research

Safety practices and opportunities for improvement in brachytherapy: A  patient safety practices survey of the American Brachytherapy Society membership
Safe delivery of brachytherapy and establishing a safety culture are critical in high-quality brachytherapy. The American Brachytherapy Society (ABS) Quality and Safety Committee surveyed members regarding brachytherapy services offered, safety practices during treatment, quality assurance procedures, and needs to develop safety and training materials. (Source: Brachytherapy)
Source: Brachytherapy - September 17, 2020 Category: Cancer & Oncology Authors: Jason C. Sanders, Timothy N. Showalter, Zoubir Ouhib, Bruce R. Thomadsen, Dayee Jacob, Manuj Agarwal, Gil'ad N. Cohen, Matt Giles, Geethpriya Palaniswammy, Abhishek A. Solanki, Neil K. Taunk, Members of the ABS Quality and Safety Committee Source Type: research

Letter to the editor on the research article “Total reference air kerma can accurately predict isodose surface volumes in cervix cancer brachytherapy. A multicenter study”
This has reference to the research article “Total reference air kerma can accurately predict isodose surface volumes in cervix cancer brachytherapy. A multicenter study.” published in your esteemed journal. The publication is good and informative; we wish to clarify following statements. (Source: Brachytherapy)
Source: Brachytherapy - September 17, 2020 Category: Cancer & Oncology Authors: Ankur Mourya, Lalit Mohan Aggarwal, Sunil Choudhary Tags: Letter to the Editor Source Type: research

HDR brachytherapy well chamber calibration and stability evaluated over twenty years of clinical use
The purpose of the study was to establish, using a retrospective analysis of existing hospital records, the long-term stability and accuracy of a high-dose-rate brachytherapy well chamber. This should be assessed to determine reliability and appropriate calibration frequency. The accrual of long-term data that demonstrates the stability of our chamber may inform others of the performance they might expect from similar equipment. (Source: Brachytherapy)
Source: Brachytherapy - September 17, 2020 Category: Cancer & Oncology Authors: Stephanie Keehan, Ryan L. Smith, Duncan Butler Source Type: research

Development, implementation, and associated challenges of a new HDR brachytherapy program
We present a simple and generic outline that lays out the process for developing and implementing a new HDR brachytherapy program in any setting, but with particular emphasis on challenges associated with starting the program in a limited resource setting. (Source: Brachytherapy)
Source: Brachytherapy - September 16, 2020 Category: Cancer & Oncology Authors: Daniel J. Scanderbeg, Catheryn Yashar, Zoubir Ouhib, Anuja Jhingran, John Einck Source Type: research

Brachytherapy in India: Learning from the past and looking into the future
India has a longstanding tradition in the practice of brachytherapy and has actively contributed to the scientific literature by conducting prospective studies, clinical audits, developing innovative techniques, and performing randomized studies. Indian investigators have also contributed to international collaborative research, education, training programs along with guideline development for brachytherapy in cervix and head and neck cancers. The present article summarizes the key contributions to scientific literature, current infrastructure, skill set for brachytherapy, existing challenges, and strategy to further stren...
Source: Brachytherapy - September 15, 2020 Category: Cancer & Oncology Authors: Anuj Kumar, Supriya Chopra, Umesh Mahantshetty, Vijay Anand Reddy Source Type: research

The ABS brachytherapy schools
The American Brachytherapy Society brachytherapy schools have been pivotal in teaching and evolving the art of brachytherapy over the past decades. Founded in 1995, the schools have consistently provided content for the major disease sites including gynecologic, prostate, and breast with ocular, vascular, head and neck, pediatric, intraluminal, systemic, and intraoperative approaches more selectively addressed. In addition, Physics schools, either coupled with clinical schools or as stand-alone venues, have provided an essential educational component for practicing physicists, a pivotal part of the brachytherapy team. (Source: Brachytherapy)
Source: Brachytherapy - September 11, 2020 Category: Cancer & Oncology Authors: Beth Erickson, Juanita Crook, Frank Vicini, Douglas Arthur, Zoubir Ouhib, Bruce Thomadsen, William Bice, Wayne M. Butler, Daniel G. Petereit, Akila N. Viswanathan Source Type: research

Evaluation and evolution of apparent diffusion coefficient (ADC) in image-guided adaptive brachytherapy (IGABT) for cervical cancer
In this study, we investigate the role of diffusion-weighted imaging –derived apparent diffusion coefficient (ADC) maps to aid in IGABT. (Source: Brachytherapy)
Source: Brachytherapy - September 11, 2020 Category: Cancer & Oncology Authors: Rishabh Kumar, Prachi Kala, Geeta S. Narayanan, Bhaskar Vishwanathan, Sowmya Narayanan, Sanjeet Mandal, Arpitha Rao, Gangadharappa Gowda Source Type: research

Addressing the burden of cervical cancer through IAEA global brachytherapy initiatives
Brachytherapy (BT) is an essential component of definitive therapy for locally advanced cervical cancer. Despite the advantages of the dose distribution with BT in cervical cancer, there is paucity of specific skills required for good-quality BT applications. Furthermore, replacing BT with other modern external beam techniques as a boost can lead to suboptimal results in cervix cancer. (Source: Brachytherapy)
Source: Brachytherapy - September 11, 2020 Category: Cancer & Oncology Authors: May Abdel-Wahab, Surbhi Grover, Eduardo Hernan Zubizarreta, Jose Alfredo Polo Rubio Source Type: research

Characterization and registration of 3D ultrasound for use in permanent breast seed implant brachytherapy treatment planning
In this study, we characterize the 3DUS system performance, establish QA baselines, and develop and test a method to register 3DUS images to CT images for PBSI planning. (Source: Brachytherapy)
Source: Brachytherapy - September 5, 2020 Category: Cancer & Oncology Authors: Claire Zhang, Michelle Hilts, Deidre Batchelar, Nathan Orlando, Lori Gardi, Aaron Fenster, Juanita Crook Source Type: research

Multimaterial three-dimensional printing in brachytherapy: Prototyping teaching tools for interstitial and intracavitary procedures in cervical cancers
As the utilization of brachytherapy procedures continues to decline in clinics, a need for accessible training tools is required to help bridge the gap between resident comfort in brachytherapy training and clinical practice. To improve the quality of intracavitary and interstitial high-dose-rate brachytherapy education, a multimaterial, modular, three-dimensionally printed pelvic phantom prototype simulating normal and cervical pathological conditions has been developed. (Source: Brachytherapy)
Source: Brachytherapy - September 5, 2020 Category: Cancer & Oncology Authors: Sabrina Campelo, Ergys Subashi, Sheridan G. Meltsner, Zheng Chang, Junzo Chino, Oana Craciunescu Source Type: research

Minimal channel GreenLight photovaporization before permanent implant prostate brachytherapy for patients with obstructive symptoms: Technically feasible and safe
Brachytherapy (BrT) is a standard treatment for low-risk to favorable-intermediate-risk prostate cancer but is a relative contraindication for patients with obstructive symptoms. We aimed to assess the feasibility and urinary toxicity of a minimal photovaporization (mPVP) before implantation. (Source: Brachytherapy)
Source: Brachytherapy - September 2, 2020 Category: Cancer & Oncology Authors: Clement Peigne, Georges Fournier, Gurvan Dissaux, Francky Delage, Jean-Baptiste Coquet, Nicolas Boussion, Gaelle Goasduff, Jean-Pierre Malhaire, Olivier Pradier, Ulrike Schick, Antoine Valeri Source Type: research

Cs-131 brachytherapy for patients with recurrent glioblastoma combined with bevacizumab avoids radiation necrosis while maintaining local control
We report the results of using intraoperative Cesium-131 (Cs-131) brachytherapy for recurrent GBM in a population of patients who also received bevacizumab. (Source: Brachytherapy)
Source: Brachytherapy - September 1, 2020 Category: Cancer & Oncology Authors: A. Gabriella Wernicke, Shoshana Taube, Andrew W. Smith, Alex Herskovic, Bhupesh Parashar, Theodore H. Schwartz Tags: Intraoperative Radiation Source Type: research

Dose to the bladder neck is not correlated with urinary toxicity in patients with prostate cancer treated with HDR brachytherapy boost
The purpose of this study was to evaluate whether the dose to bladder neck (BN) is a predictor of acute and late urinary toxicity after high-dose-rate brachytherapy (HDRB) boost for prostate cancer. (Source: Brachytherapy)
Source: Brachytherapy - September 1, 2020 Category: Cancer & Oncology Authors: Ibtihel Ben Aicha, Lara Hathout, Damien Carignan, Philippe Despr és, Marie-Claude Lavallée, Sylviane Aubin, Luc Beaulieu, Frédéric Lacroix, William Foster, André-Guy Martin, Eric Vigneault Tags: Prostate Source Type: research

Editorial Board
(Source: Brachytherapy)
Source: Brachytherapy - September 1, 2020 Category: Cancer & Oncology Source Type: research

Masthead
(Source: Brachytherapy)
Source: Brachytherapy - September 1, 2020 Category: Cancer & Oncology Source Type: research

Table of Contents
(Source: Brachytherapy)
Source: Brachytherapy - September 1, 2020 Category: Cancer & Oncology Source Type: research

A national surveillance study of the current status of reirradiation using brachytherapy in Japan
This study aimed to explore the current status and pattern of practice for reirradiation using brachytherapy (ReRT-BT) through a survey in Japan. (Source: Brachytherapy)
Source: Brachytherapy - September 1, 2020 Category: Cancer & Oncology Authors: Hideya Yamazaki, Koji Masui, Daisuke Shimizu, Gen Suzuki, Fumiaki Isohashi, Ken yoshida, JBReRT Group Source Type: research

Medical malpractice and brachytherapy
On average, physicians spend 10 years embroiled in malpractice litigation, exacerbating burnout and depression. Only a limited number of studies regarding medical malpractice in radiation oncology have been published, mostly in the last few years. We undertook this review with the goal of looking specifically at brachytherapy-related medical malpractice literature. (Source: Brachytherapy)
Source: Brachytherapy - September 1, 2020 Category: Cancer & Oncology Authors: Kent Wallner, Guila Delouya, Tony S. Quang Source Type: research

What is the dosimetric impact of isotropic vs anisotropic safety margins for delineation of the clinical target volume in breast brachytherapy?
The purpose of the study was to report dosimetric differences for breast brachytherapy plans optimized for clinical target volume (CTV) generated using conventional isotropic expansion of tumor bed volume (TBV) and Groupe Europ éen de Curiethérapie–European Society for Radiotherapy and Oncology (GEC-ESTRO) recommendations to expand the TBV anisotropically to achieve a total safety margin of 2 cm (resection margin size + added safety margin). (Source: Brachytherapy)
Source: Brachytherapy - September 1, 2020 Category: Cancer & Oncology Authors: Anuj Kumar, Tabassum Wadasadawala, Kishore Joshi, Rima Pathak, Libin Scaria, Ritu Raj Upreti, Rajesh Bhajbhuje, Tanuja Shet, Vani Parmar, Sudeep Gupta, Smruti Mokal, Rajiv Sarin Source Type: research

Brachytherapy Care during the COVID-19 Pandemic: Practice Statement from a Cancer Center in Wuhan, China
COVID-19 broke out in late 2019 and rapidly spread around the world and became a pandemic. This highly contagious disease affects routine health care services and cancer patients who are susceptible to it. Delivering brachytherapy on time is critical for cancer patients to get better prognosis. The purpose of this study is to present workflow and standard for radiation centers to deliver brachytherapy and avoid cross-infection during the COVID-19 pandemic. (Source: Brachytherapy)
Source: Brachytherapy - August 26, 2020 Category: Cancer & Oncology Authors: Yao Jiang, Guiling Li, Biyuan Xing, Ye Wang, Zhao Liu, Yingchao Zhao Source Type: research

Real-world dosimetric comparison between CyberKnife SBRT and HDR brachytherapy for the treatment of prostate cancer
We present here a real-word dosimetric comparison between SBRT and ultrasound-based virtual HDR-BRT, with both imaging modalities coming from the same patient. (Source: Brachytherapy)
Source: Brachytherapy - August 18, 2020 Category: Cancer & Oncology Authors: Georgios Chatzikonstantinou, Christian Keller, Christian Scherf, Bastian Bathen, Janett K öhn, Nikolaos Tselis Source Type: research

Initial experience and lessons learned with implementing Lutetium-177-dotatate radiopharmaceutical therapy in a radiation oncology –based program
To assist radiation oncology centers in implementing Lutetium-177-dotatate (177Lu) radiopharmaceutical therapy for midgut neuroendocrine tumors. Here we describe our workflow and how it was revised based on our initial experience on an expanded access protocol (EAP). (Source: Brachytherapy)
Source: Brachytherapy - August 17, 2020 Category: Cancer & Oncology Authors: Nichole M. Maughan, Hyun Kim, Yao Hao, Samantha Unangst, Michael C. Roach, Jose L. Garcia-Ramirez, Max Amurao, David Luechtefeld, Kinda Abdin, Michael B. Altman, Alexis Banks, Mary Riepe, Erica Bovard, Samantha Jenkins, Jacqueline E. Zoberi Source Type: research

Education and training for image-guided adaptive brachytherapy for cervix cancer —The (GEC)-ESTRO/EMBRACE perspective
Image-guided adaptive brachytherapy (IGABT) has been shown to improve local/regional control and survival for cervix cancer patients while reducing morbidity. However, the technique is complex involving several conceptual, methodological, and technical innovations compared to conventional brachytherapy. The delivery of high-quality IGABT which will translate into improved outcomes is therefore critically dependent on effective education and training of all health professionals involved in the brachytherapy treatment process. (Source: Brachytherapy)
Source: Brachytherapy - August 16, 2020 Category: Cancer & Oncology Authors: Li-Tee Tan, Kari Tanderup, Christian Kirisits, Umesh Mahantshetty, Jamema Swamidas, Ina J ürgenliemk-Schulz, Jacob Lindegaard, Astrid de Leeuw, Nicole Nesvacil, Marianne Assenholt, Daniel Berger, Tamara Diendorfer, Johannes Dimopoulos, Simon Duke, Stefan Source Type: research

#ThisIsBrachytherapy: Increasing awareness of brachytherapy
The use of brachytherapy continues to be a vital application of radiation oncology for various cancers. Despite this, there has been a decrease in the utilization of brachytherapy in many cancers. Social media in medicine facilitates engagement and advocacy. We launched a social media campaign to bring awareness of brachytherapy throughout the world with #ThisIsBrachytherapy hashtag on July 17,  2019. (Source: Brachytherapy)
Source: Brachytherapy - August 16, 2020 Category: Cancer & Oncology Authors: Jenna M. Kahn, Shauna R. Campbell, Ashley A. Albert, Miriam A. Knoll, Chirag Shah Source Type: research

Time to achieve a prostate-specific antigen nadir of ≤0.2 ng/mL and related factors after permanent prostate brachytherapy
The purpose of this study was to identify the time to achieve a prostate-specific antigen (PSA) nadir of ≤0.2 ng/mL and the related factors to achieve this goal. (Source: Brachytherapy)
Source: Brachytherapy - August 16, 2020 Category: Cancer & Oncology Authors: Takashi Soyano, Atsunori Yorozu, Nana Natsume, Takashi Hanada, Yutaka Shiraishi, Kazuhito Toya, Shiro Saito Source Type: research

A comparison between revised Manchester Point A and ICRU-89 –recommended Point A definition absorbed-dose reporting using CT images in intracavitary brachytherapy for patients with cervical carcinoma
This study is a comparison between revised Manchester Point A and International Commission on Radiation Units and measurements (ICRU) 89 report –recommended Point A absorbed-dose reporting in intracavitary brachytherapy for patients with cervical carcinoma. (Source: Brachytherapy)
Source: Brachytherapy - August 16, 2020 Category: Cancer & Oncology Authors: Ankur Mourya, Sunil Choudhary, Uday Pratap Shahi, Neeraj Sharma, Himani Gautam, Ganeshkumar Patel, Satyajit Pradhan, Lalit Mohan Aggarwal Source Type: research

Interstitial high-dose-rate brachytherapy in the treatment of keloids: Moving toward a volumetric approach
Brachytherapy (BT) after surgical resection of keloids reduces the risk of local recurrence, but standardization of dose/technique is lacking. Typical keloid BT treatment utilizes a single-channel source prescribed to 5-mm depth. We investigated the dosimetry of a volume-based target definition for interstitial high-dose-rate BT treatment of keloids. (Source: Brachytherapy)
Source: Brachytherapy - August 15, 2020 Category: Cancer & Oncology Authors: Eric M. Anderson, John David, Tiffany Phillips, John Demarco, Robert S. Reznik, Amin J. Mirhadi, Mitchell Kamrava Source Type: research

Salvage low-dose-rate brachytherapy for local recurrences after prostatectomy and adjuvant or salvage external beam irradiation: Feasibility study on five patients and literature review
To assess the feasibility and tumor outcome of re-irradiation with low-dose-rate brachytherapy for macroscopic local recurrences after radical prostatectomy (RP) followed by adjuvant or salvage external beam radiation therapy (EBRT). (Source: Brachytherapy)
Source: Brachytherapy - August 12, 2020 Category: Cancer & Oncology Authors: Charlotte Le Roy, Fr édéric Gassa, Olivier Rouvière, Olivier Desmettre, Gabriel Bringeon, Julien Charret, Anne-Agathe Serre, Pascal Pommier Source Type: research

More than learning technical skills: The importance of mentorship and coaching during a brachytherapy fellowship
Brachytherapy exposure during residency varies between residency training programs. As a result, many graduating radiation oncology residents do not feel competent or confident in performing brachytherapy procedures. A brachytherapy fellowship encompasses hands-on procedural skills in addition to clinical decision-making, radiotherapy treatment planning, as well as post-treatment care. During this time, a fellow develops interpersonal relationships with their faculty supervisors in the form of mentorship, sponsorship, and coaching in addition to clinical teaching. (Source: Brachytherapy)
Source: Brachytherapy - August 12, 2020 Category: Cancer & Oncology Authors: Jennifer Croke, Amandeep Taggar, Anthony Fyles, Michael Milosevic Source Type: research

Paracervical Blocks Facilitate Timely Brachytherapy Amidst COVID-19
The COVID-19 pandemic presents serious challenges for brachytherapists, and in the time-sensitive case of locally advanced cervical cancer (LACC), the need for curative brachytherapy (BT) is critical for survival. Given the high-volume of LACC in our safety-net hospital, we developed a strategy in close collaboration with our gynecology oncology and anesthesia colleagues to allow for completely clinic-based ICBT. (Source: Brachytherapy)
Source: Brachytherapy - August 7, 2020 Category: Cancer & Oncology Authors: Daniel Brunnhoelzl, Alexander N. Hanania, Alfredo Echeverria, Jan Sunde, Connie Tran, Michelle Ludwig Source Type: research

I-125 or Pd-103 for brachytherapy boost in men with high-risk prostate cancer: A comparison of survival and morbidity outcomes
Brachytherapy boost improves biochemical recurrence rates in men with high-risk prostate cancer (HRPC). Few data are available on whether one isotope is superior to another. We compared the oncologic and morbidity outcomes of I-125 and Pd-103 in men with HRPC receiving brachytherapy. (Source: Brachytherapy)
Source: Brachytherapy - August 3, 2020 Category: Cancer & Oncology Authors: Nelson N. Stone, Vassilios M. Skouteris, Barry S. Rosenstein, Richard G. Stock Source Type: research

Applicator visualization using ultrashort echo time MRI for high-dose-rate endorectal brachytherapy
The individual channels in an endorectal applicator for high-dose-rate endorectal brachytherapy are not visible on standard MRI sequences. The aim of this study was to test whether an ultrashort echo time (UTE) MRI sequence could be used to visualize the individual channels to enable MR-only treatment planning for rectal cancer. (Source: Brachytherapy)
Source: Brachytherapy - July 31, 2020 Category: Cancer & Oncology Authors: Roy .P.J. van den Ende, Ece Ercan, Rick Keesman, Ellen M. Kerkhof, Corrie .A.M. Marijnen, Uulke A. van der Heide Source Type: research

Predicting adherence of dose –volume constraints for personalized partial-breast irradiation technique
We examined the impact of EB-PBI on dose –volume constraints as compared to MIB-PBI. (Source: Brachytherapy)
Source: Brachytherapy - July 30, 2020 Category: Cancer & Oncology Authors: Kazuhiko Sato, Takahiro Shimo, Hiromi Fuchikami, Naoko Takeda, Masahiro Kato, Tomohiko Okawa Source Type: research

A reliable skin toxicity predictor in permanent breast seed implant brachytherapy
To establish skin dose –outcome relationships using a reliable metric in permanent breast seed implant (PBSI). (Source: Brachytherapy)
Source: Brachytherapy - July 29, 2020 Category: Cancer & Oncology Authors: Zahra Anjomani, Michelle Hilts, Deidre Batchelar, Juanita Crook Source Type: research

Evaluating the impact of real-time multicriteria optimizers integrated with interactive plan navigation tools for HDR brachytherapy
This study aims to quantify planning efficiency gains when using a graphics processing unit –based MCO (gMCO) algorithm combined with a novel graphical user interface (gMCO-GUI) that integrates efficient automated and interactive plan navigation tools. (Source: Brachytherapy)
Source: Brachytherapy - July 23, 2020 Category: Cancer & Oncology Authors: C édric Bélanger, Éric Poulin, Songye Cui, Éric Vigneault, André-Guy Martin, William Foster, Philippe Després, J. Adam M. Cunha, Luc Beaulieu Source Type: research

Evaluation of an MR-only interstitial gynecologic brachytherapy workflow using MR-line marker for catheter reconstruction
This study aims to evaluate the feasibility of MR-only workflow using an in-house MR line marker during interstitial gynecological high-dose-rate (HDR) brachytherapy. (Source: Brachytherapy)
Source: Brachytherapy - July 22, 2020 Category: Cancer & Oncology Authors: Amani Shaaer, Moti Paudel, Mackenzie Smith, Frances Tonolete, Alexandru Nicolae, Eric Leung, Ananth Ravi Source Type: research

Dosimetric evaluation of MRI-to-ultrasound automated image registration algorithms for prostate brachytherapy
This study assesses the dosimetric impact attributed to differences in DIL contours generated using commonly available MRI to TRUS automated registration: rigid, semi-rigid, and deformable image registration, respectively. (Source: Brachytherapy)
Source: Brachytherapy - July 22, 2020 Category: Cancer & Oncology Authors: Amani Shaaer, Moti Paudel, Melanie Davidson, Mark Semple, Alexandru Nicolae, Lucas Castro Mendez, Hans Chung, Andrew Loblaw, Chia-Lin Tseng, Gerard Morton, Ananth Ravi Source Type: research

Low-cost 3D print –based phantom fabrication to facilitate interstitial prostate brachytherapy training program
The purpose of this study was to manufacture a realistic and inexpensive prostate phantom to support training programs for ultrasound-based interstitial prostate brachytherapy. (Source: Brachytherapy)
Source: Brachytherapy - July 17, 2020 Category: Cancer & Oncology Authors: Tsuicheng Chiu, Zhenyu Xiong, David Parsons, Michael R. Folkert, Paul M. Medin, Brian Hrycushko Source Type: research

Defining dose constraints for catheter insertion sites to minimize toxicity after interstitial breast brachytherapy
The purpose of this study was to define dose constraints for catheter insertion sites to minimize probability of prominent post-therapy skin marks after interstitial breast brachytherapy. (Source: Brachytherapy)
Source: Brachytherapy - July 16, 2020 Category: Cancer & Oncology Authors: Revathy Krishnamurthy, Tabassum Wadasadawala, Pallavi Rane, Reena Phurailatpam, Rajiv Sarin Source Type: research

Prostate brachytherapy intraoperative dosimetry using a combination of radiographic seed localization with a C-arm and deformed ultrasound prostate contours
The purpose of the study was to assess the feasibility of performing intraoperative dosimetry for permanent prostate brachytherapy by combining transrectal ultrasound (TRUS) and fluoroscopy/cone beam CT [CBCT] images and accounting for the effect of prostate deformation. (Source: Brachytherapy)
Source: Brachytherapy - July 15, 2020 Category: Cancer & Oncology Authors: Maryam Golshan, S. Sara Mahdavi, Golnoosh Samei, Julio Lobo, Tom Pickles, W. James Morris, Mira Keyes, Michael Peacock, Septimiu E. Salcudean, Ingrid Spadinger Source Type: research

Evaluating reimbursement of skin radiation therapy: Technique and fractionation
Multiple skin radiation therapy techniques exist including electron beam therapy, high-dose-rate (HDR) brachytherapy, superficial/orthovoltage, and electronic brachytherapy (EB). The purpose of this analysis was to compare reimbursement between these modalities by fractionation regimen. (Source: Brachytherapy)
Source: Brachytherapy - July 15, 2020 Category: Cancer & Oncology Authors: Chirag Shah, Mitchell Kamrava, Nikhil G. Thaker Source Type: research

Patient selection and a brief review of consensus recommendations from around the globe
Keratinocyte carcinomas (KCs, previous nonmelanoma skin cancer) incorporate basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC). These are the most common cancers worldwide with a growing incidence [1,2]. Although commonly treated with surgery alone, for decades, radiation therapy has served as an alternative for definitive treatment as well as adjuvant treatment in high-risk patients after surgery. Multiple radiation therapy techniques are available including external beam radiation therapy with electrons or photons (superficial, orthovoltage, or megavoltage) as well as brachytherapy (radionuclide or e...
Source: Brachytherapy - July 15, 2020 Category: Cancer & Oncology Authors: Chirag Shah, Nikhil Joshi Tags: Review Article Source Type: research

Predictors of urinary toxicity with MRI-assisted radiosurgery for low-dose-rate prostate brachytherapy
MRI-assisted radiosurgery (MARS) is a modern technique for prostate brachytherapy that provides superior soft tissue contrast. The purpose of this analysis was to evaluate treatment planning factors associated with urinary toxicity, particularly damage to the membranous urethra (MUL) and external urethral sphincter (EUS), after MARS. (Source: Brachytherapy)
Source: Brachytherapy - July 15, 2020 Category: Cancer & Oncology Authors: David Boyce-Fappiano, Tharakeswara K. Bathala, Rong Ye, Dario Pasalic, Olsi Gjyshi, Todd A. Pezzi, Sonal S. Noticewala, Gwendolyn J. McGinnis, Sean Maroongroge, Deborah A. Kuban, Quynh-Nhu Nguyen, Sean E. McGuire, Karen E. Hoffman, Seungtaek Choi, Chad Ta Source Type: research

Adjuvant electronic brachytherapy for endometrial carcinoma: A 4-year outcomes report
The purpose of the study was to report the outcomes of a single-center adjuvant electronic brachytherapy (e-BT) experience for patients with endometrial carcinoma. (Source: Brachytherapy)
Source: Brachytherapy - July 7, 2020 Category: Cancer & Oncology Authors: Gustavo R. Sarria, Elena Sperk, Frederik Wenz, Frank Schneider, Yasser Abo-Madyan, Frank A. Giordano, Michael Ehmann Source Type: research

Techniques for and uncertainties of MRI-based reconstruction of titanium tandem and ring brachytherapy applicators
Eliminating patient computed tomography (CT) scans for tandem and ring (T&R) brachytherapy can reduce overall procedure time and eliminates imaging dose. However, reconstructing titanium applicators in magnetic resonance imaging (MRI) is challenging. We evaluated the uncertainty of different applicator reconstruction workflows in MR-guided brachytherapy, and assessed the clinical impact of reconstruction uncertainties. (Source: Brachytherapy)
Source: Brachytherapy - July 3, 2020 Category: Cancer & Oncology Authors: Irina Malajovich, Shibu Anamalayil, Otilia Valentina Dolney, Boon-Keng Kevin Teo, William Tristram Arscott, Neil K. Taunk Source Type: research

A semiautomatic segmentation method for interstitial needles in intraoperative 3D transvaginal ultrasound images for high-dose-rate gynecologic brachytherapy of vaginal tumors
The purpose of this study was to evaluate the use of a semiautomatic algorithm to simultaneously segment multiple high-dose-rate (HDR) gynecologic interstitial brachytherapy (ISBT) needles in three-dimensional (3D) transvaginal ultrasound (TVUS) images, with the aim of providing a clinically useful tool for intraoperative implant assessment. (Source: Brachytherapy)
Source: Brachytherapy - July 3, 2020 Category: Cancer & Oncology Authors: Jessica Robin Rodgers, William Thomas Hrinivich, Kathleen Surry, Vikram Velker, David D'Souza, Aaron Fenster Source Type: research

Overall survival comparison between androgen deprivation therapy (ADT) plus external beam radiation therapy (EBRT) vs ADT plus EBRT with brachytherapy boost in clinically node-positive prostate cancer
Optimal therapy for clinically node-positive, nonmetastatic (cN1) prostate cancer (PC) patients remains controversial, ranging from aggressive local therapy to palliative systematic therapy alone. Despite guideline support, it is unclear if a brachytherapy (BT) boost should be considered for cN1 patients as these patients were excluded from randomized trials establishing its benefit. Herein, we compare definitive radiation therapy (RT) with or without a BT boost in cN1 PC. (Source: Brachytherapy)
Source: Brachytherapy - July 3, 2020 Category: Cancer & Oncology Authors: Benjamin W. Fischer-Valuck, Yuan James Rao, Randall J. Brenneman, Pretesh R. Patel, Christopher P. Filson, Ashesh B. Jani, Yuan Liu, Subir Goyal, Karen Xu, Aaron Weiss, Omer Kucuk, Cara Cimmino, Stephen Szabo, Peter Rossi, Brian C. Baumann, John Pattaras, Source Type: research