Hypofractionated palliative volumetric modulated arc radiotherapy with the Radiation Oncology Study Group 8502 “QUAD shot” regimen for incurable head and neck cancer
To review a single institutional experience of the Radiation Therapy Oncology Group (RTOG) 8502 “QUAD shot” regimen using volumetric modulated arc radiotherapy (VMAT) for incurable head and neck cancer (HNC). (Source: Radiation Oncology)
Source: Radiation Oncology - May 27, 2020 Category: Cancer & Oncology Authors: Ryo Toya, Tetsuo Saito, Kohsei Yamaguchi, Tomohiko Matsuyama, Takahiro Watakabe, Tadashi Matsumoto, Ryoji Yoshida, Akiyuki Hirosue, Daizo Murakami, Yorihisa Orita, Hideki Nakayama and Natsuo Oya Tags: Research Source Type: research

Investigating the loco-regional control of simultaneous integrated boost intensity-modulated radiotherapy with different radiation fraction sizes for locally advanced non-small-cell lung cancer: clinical outcomes and the application of an extended LQ/TCP model
To investigate the loco-regional progression-free survival (LPFS) of intensity-modulated radiotherapy (IMRT) with different fraction sizes for locally advanced non-small-cell lung cancer (LANSCLC), and to appl... (Source: Radiation Oncology)
Source: Radiation Oncology - May 27, 2020 Category: Cancer & Oncology Authors: Bo Qiu, Qi Wen Li, Xin Lei Ai, Bin Wang, Jian Huan, Zheng Fei Zhu, Gen Hua Yu, Ming Ji, Hai Hang Jiang, Cheng Li, Jun Zhang, Li Chen, Jin Yu Guo, Yin Zhou and Hui Liu Tags: Research Source Type: research

Patterns of recurrence in anal cancer: a detailed analysis
Anal cancer is a rare disease, which might be the reason for the “one size fits all” approach still used for radiotherapy target contouring. To refine and individualize future guidelines, detailed and contempo... (Source: Radiation Oncology)
Source: Radiation Oncology - May 27, 2020 Category: Cancer & Oncology Authors: Martin P. Nilsson, Erik D. Nilsson, Anders Johnsson, Otilia Leon, Adalsteinn Gunnlaugsson and Jonas Scherman Tags: Research Source Type: research

The effect of primary tumor radiotherapy in patients with Unresectable stage IV Rectal or Rectosigmoid Cancer: a propensity score matching analysis for survival
To evaluate the impact of primary tumor radiotherapy on survival in patients with unresectable metastatic rectal or rectosigmoid cancer. (Source: Radiation Oncology)
Source: Radiation Oncology - May 27, 2020 Category: Cancer & Oncology Authors: Gang Wang, Wenling Wang, Haijie Jin, Hongmin Dong, Weiwei Chen, Xiaokai Li, Guodong Li and Leilei Li Tags: Research Source Type: research

Preliminary result of carbon-ion radiotherapy using the spot scanning method for prostate cancer
Carbon-ion radiotherapy (CIRT) for prostate cancer was initiated at Kanagawa Cancer Center in 2015. The present study analyzed the preliminary clinical outcomes of CIRT for prostate cancer. (Source: Radiation Oncology)
Source: Radiation Oncology - May 27, 2020 Category: Cancer & Oncology Authors: Yosuke Takakusagi, Hiroyuki Katoh, Kio Kano, Wataru Anno, Keisuke Tsuchida, Nobutaka Mizoguchi, Itsuko Serizawa, Daisaku Yoshida and Tadashi Kamada Tags: Research Source Type: research

Management of anal cancer patients – a pattern of care analysis in German-speaking countries
Radiotherapy dose and target volume prescriptions for anal squamous cell carcinoma (ASCC) vary considerably in daily practice and guidelines, including those from NCCN, UK, Australasian, and ESMO. We conducted... (Source: Radiation Oncology)
Source: Radiation Oncology - May 25, 2020 Category: Cancer & Oncology Authors: Daniel Martin, Jens von der Gr ün, Claus Rödel and Emmanouil Fokas Tags: Research Source Type: research

Volumetric modulated arc therapy versus intensity-modulated proton therapy in neoadjuvant irradiation of locally advanced oesophageal cancer
To investigate the role of intensity-modulated proton therapy (IMPT) compared to volumetric modulated arc therapy (VMAT), realised with RapidArc and RapidPlan methods (RA_RP) for neoadjuvant radiotherapy in lo... (Source: Radiation Oncology)
Source: Radiation Oncology - May 24, 2020 Category: Cancer & Oncology Authors: Eren Celik, Wolfgang Baus, Christian Baues, Wolfgang Schr öder, Alessandro Clivio, Antonella Fogliata, Marta Scorsetti, Simone Marnitz and Luca Cozzi Tags: Research Source Type: research

Stability and reproducibility of 6013 deep inspiration breath-holds in left-sided breast cancer
Patients with left-sided breast cancer frequently receive deep inspiration breath-hold (DIBH) radiotherapy to reduce the risk of cardiac side effects. The aim of the present study was to analyze intra-breath-h... (Source: Radiation Oncology)
Source: Radiation Oncology - May 24, 2020 Category: Cancer & Oncology Authors: D. Reitz, F. Walter, S. Sch önecker, P. Freislederer, M. Pazos, M. Niyazi, G. Landry, F. Alongi, E. Bölke, C. Matuschek, M. Reiner, C. Belka and S. Corradini Tags: Research Source Type: research

Heart sparing radiotherapy in breast cancer: the importance of baseline cardiac risks
Patients with left-sided breast cancer have an increased risk of cardiovascular disease (CVD) after radiotherapy (RT). While the awareness of cardiac toxicity has increased enormously over the last decade, the... (Source: Radiation Oncology)
Source: Radiation Oncology - May 24, 2020 Category: Cancer & Oncology Authors: Aur élie Gaasch, Stephan Schönecker, Cristoforo Simonetto, Markus Eidemüller, Montserrat Pazos, Daniel Reitz, Maya Rottler, Philipp Freislederer, Michael Braun, Rachel Würstlein, Nadia Harbeck, Maximilian Niyazi, Claus Belka and Stefanie Corradini Tags: Research Source Type: research

Efficacy of adjuvant radiotherapy for treatment of adrenocortical carcinoma: a retrospective study and an updated meta-analysis
Adrenocortical carcinoma (ACC) is a rare and highly aggressive malignancy. Surgical resection is the standard treatment for localized ACC, but the local recurrence remains high. Adjuvant radiation (ART) has be... (Source: Radiation Oncology)
Source: Radiation Oncology - May 24, 2020 Category: Cancer & Oncology Authors: Jiawei Zhu, Ziye Zheng, Jing Shen, Xin Lian, Zheng Miao, Jie Shen and Fuquan Zhang Tags: Research Source Type: research

Postoperative adjuvant chemotherapy versus chemoradiotherapy for node-positive esophageal squamous cell carcinoma: a propensity score-matched analysis
After esophagectomy, adjuvant chemotherapy (S  + CT) and adjuvant chemoradiotherapy (S + CRT) can improve survival in patients with node-positive resectable esophageal cancer. However, we are not aware of any s... (Source: Radiation Oncology)
Source: Radiation Oncology - May 24, 2020 Category: Cancer & Oncology Authors: Qifeng Wang, Jinyi Lang, Tao Li, Lin Peng, Wei Dai, Yinchun Jiang, Tianpeng Xie, Qiang Fang, Yi Wang, Lei Wu, Bangrong Cao and Yongtao Han Tags: Research Source Type: research

Factors affecting outcome in frameless non-isocentric stereotactic radiosurgery for trigeminal neuralgia: a multicentric cohort study
Stereotactic radiosurgery (SRS) is an effective treatment for trigeminal neuralgia (TN). Nevertheless, a proportion of patients will experience recurrence and treatment-related sensory disturbances. In order t... (Source: Radiation Oncology)
Source: Radiation Oncology - May 22, 2020 Category: Cancer & Oncology Authors: Alfredo Conti, Gueliz Acker, Antonio Pontoriero, Juliane Hardt, Anne Kluge, Alberto Cacciola, Giuseppe Iat ì, Markus Kufeld, Volker Budach, Peter Vajkoczy, Giancarlo Beltramo, Stefano Pergolizzi, Achille Bergantin, Franziska Loebel, Silvana Parisi, Carol Tags: Research Source Type: research

Prognostic value of sarcopenia in patients treated by Radiochemotherapy for locally advanced oesophageal cancer
Sarcopenia is defined by a loss of skeletal muscle mass with or without loss of fat mass. Sarcopenia has been associated to reduced tolerance to treatment and worse prognosis in cancer patients, including pati... (Source: Radiation Oncology)
Source: Radiation Oncology - May 22, 2020 Category: Cancer & Oncology Authors: Romain Mallet, Romain Modzelewski, Justine Lequesne, Sorina Mihailescu, Pierre Decazes, Hugues Auvray, Ahmed Benyoucef, Fr éderic Di Fiore, Pierre Vera, Bernard Dubray and Sébastien Thureau Tags: Research Source Type: research

Radiotherapy for nonagenarians: the value of biological versus chronological age
The number of nonagenarian cancer patients ( ≥ 90 years) is continuously increasing, and radiotherapy is performed in a relevant proportion of patients, as surgery and chemotherapy are often not feasible for th... (Source: Radiation Oncology)
Source: Radiation Oncology - May 19, 2020 Category: Cancer & Oncology Authors: Tanja Sprave, Alexander R ühle, Raluca Stoian, Alina Weber, Constantinos Zamboglou, Carsten Nieder, Anca-Ligia Grosu and Nils H. Nicolay Tags: Research Source Type: research

Predicting per-lesion local recurrence in locally advanced non-small cell lung cancer following definitive radiation therapy using pre- and mid-treatment metabolic tumor volume
We evaluated whether pre- and mid-treatment metabolic tumor volume (MTV) predicts per lesion local recurrence (LR) in patients treated with definitive radiation therapy (RT, dose ≥60 Gy) for locally advanced no... (Source: Radiation Oncology)
Source: Radiation Oncology - May 19, 2020 Category: Cancer & Oncology Authors: Michael S. Binkley, Julie L. Koenig, Mehr Kashyap, Michael Xiang, Yufei Liu, Quaovi Sodji, Peter G. Maxim, Maximilian Diehn, Billy W. Loo Jr and Michael F. Gensheimer Tags: Research Source Type: research

Radiation induced temporal lobe necrosis in nasopharyngeal cancer patients after radical external beam radiotherapy
Radiation-induced temporal lobe necrosis (TLN) is one of the late post-radiotherapy complications in nasopharyngeal cancer (NPC) patients. Since NPC is common to have skull base infiltration, irradiation of th... (Source: Radiation Oncology)
Source: Radiation Oncology - May 15, 2020 Category: Cancer & Oncology Authors: Vincent W. C. Wu and Shing-yau Tam Tags: Review Source Type: research

Single-center versus multi-center data sets for molecular prognostic modeling: a simulation study
Prognostic models based on high-dimensional omics data generated from clinical patient samples, such as tumor tissues or biopsies, are increasingly used for prognosis of radio-therapeutic success. The model de... (Source: Radiation Oncology)
Source: Radiation Oncology - May 14, 2020 Category: Cancer & Oncology Authors: Daniel Samaga, Roman Hornung, Herbert Braselmann, Julia Hess, Horst Zitzelsberger, Claus Belka, Anne-Laure Boulesteix and Kristian Unger Tags: Research Source Type: research

Intraoperative radiotherapy with low energy x-rays for primary and recurrent soft-tissue sarcomas
Soft tissue sarcomas (STS) treatment remains a therapeutic challenge. Intraoperative radiotherapy (IORT) resembles a safe and efficient for STS treatment. The first data on electronic-IORT (eIORT) using low-en... (Source: Radiation Oncology)
Source: Radiation Oncology - May 14, 2020 Category: Cancer & Oncology Authors: Gustavo R. Sarria, Vera Petrova, Frederik Wenz, Yasser Abo-Madyan, Elena Sperk and Frank A. Giordano Tags: Research Source Type: research

Altered fractionation short-course radiotherapy for stage II-III rectal cancer: a retrospective study
To report the long-term outcomes of neoadjuvant altered fractionation short-course radiotherapy in 271 consecutive patients with stage II-III rectal cancer. (Source: Radiation Oncology)
Source: Radiation Oncology - May 14, 2020 Category: Cancer & Oncology Authors: Hans Geinitz, Carsten Nieder, Lukas Kocik, Christine Track, Johann Feichtinger, Theresa Weingartner, Kurt Spiegl, Barbara F üreder-Kitzmüller, Johanna Kaufmann, Dietmar H. Seewald, Reinhold Függer, Andreas Shamiyeh, Andreas L. Petzer, David Kiesl and J Tags: Research Source Type: research

Atlas-based auto-segmentation for postoperative radiotherapy planning in endometrial and cervical cancers
This study evaluated the feasibility of atlas-ba... (Source: Radiation Oncology)
Source: Radiation Oncology - May 13, 2020 Category: Cancer & Oncology Authors: Nalee Kim, Jee Suk Chang, Yong Bae Kim and Jin Sung Kim Tags: Research Source Type: research

Effect of neoadjuvant radiotherapy on survival of non-metastatic pancreatic ductal adenocarcinoma: a SEER database analysis
Neoadjuvant radiotherapy has been shown to improve marginal negative resection and local control of Pancreatic Ductal Adenocarcinoma (PDAC). However, whether it improves overall survival (OS) in patients with ... (Source: Radiation Oncology)
Source: Radiation Oncology - May 13, 2020 Category: Cancer & Oncology Authors: Dan Wang, Chongshun Liu, Yuan Zhou, Tingyu Yan, Chenglong Li, Qionghui Yang, Yang Xu, Lilan Zhao, Qian Pei, Fengbo Tan, Cenap G üngör and Yuqiang Li Tags: Research Source Type: research

Stereotactic body radiation therapy in the treatment of ovarian cancer
This study evaluates the outcomes and toxicity of stereotactic body radiation therapy (SBRT) in ovarian cancer. (Source: Radiation Oncology)
Source: Radiation Oncology - May 13, 2020 Category: Cancer & Oncology Authors: Roman O. Kowalchuk, Michael R. Waters, K. Martin Richardson, Kelly Spencer, James M. Larner, William P. Irvin and Charles R. Kersh Tags: Research Source Type: research

Clinical implementation of MRI-based organs-at-risk auto-segmentation with convolutional networks for prostate radiotherapy
Structure delineation is a necessary, yet time-consuming manual procedure in radiotherapy. Recently, convolutional neural networks have been proposed to speed-up and automatise this procedure, obtaining promis... (Source: Radiation Oncology)
Source: Radiation Oncology - May 11, 2020 Category: Cancer & Oncology Authors: Mark H. F. Savenije, Matteo Maspero, Gonda G. Sikkes, Jochem R. N. van der Voort van Zyp, Alexis N. T. J. Kotte, Gijsbert H. Bol and Cornelis A. T. van den Berg Tags: Research Source Type: research

Design and fabrication of a Nano-based neutron shield for fast neutrons from medical linear accelerators in radiation therapy
Photo-neutrons are produced at the head of the medical linear accelerators (linac) by the interaction of high-energy photons, and patients receive a whole-body-absorbed dose from these neutrons. The current st... (Source: Radiation Oncology)
Source: Radiation Oncology - May 11, 2020 Category: Cancer & Oncology Authors: Younes Afkham, Asghar Mesbahi, Abdolali Alemi, Farhad Zolfagharpour and Nasrollah Jabbari Tags: Research Source Type: research

Evaluating dosimetric constraints for carbon ion radiotherapy in the treatment of locally advanced pancreatic cancer
To identify a safe carbon ion radiotherapy (CIRT) regimen for patients with locally advanced pancreatic cancer (LAPC). (Source: Radiation Oncology)
Source: Radiation Oncology - May 7, 2020 Category: Cancer & Oncology Authors: Lien-Chun Lin, Guo-Liang Jiang, Nitin Ohri, Zheng Wang, Jiade J. Lu, Madhur Garg, Chandan Guha and Xiaodong Wu Tags: Methodology Source Type: research

Longitudinal atherosclerotic changes after radio(chemo)therapy of hypopharyngeal carcinoma
This study aimed at a closer characterization of this damage and its development in time with a longitudi... (Source: Radiation Oncology)
Source: Radiation Oncology - May 7, 2020 Category: Cancer & Oncology Authors: Cristoforo Simonetto, Michael Mayinger, Thamer Ahmed, Kai Borm, Pavel Kundr át, Steffi Pigorsch, Jan Christian Kaiser and Stephanie E. Combs Tags: Research Source Type: research

Impact of positioning errors in the dosimetry of VMAT left-sided post mastectomy irradiation
Volumetric modulated arc therapy (VMAT) adopted in post-mastectomy radiation therapy (PMRT) has the capacity to achieve highly conformal dose distributions. The research aims to evaluate the impact of position... (Source: Radiation Oncology)
Source: Radiation Oncology - May 7, 2020 Category: Cancer & Oncology Authors: Xiongfei Liao, Fan Wu, Junxiang Wu, Qian Peng, Xinghong Yao, Shengwei Kang, Yanqun Zhao and Lucia Clara Orlandini Tags: Research Source Type: research

The effect of hyperbaric oxygen therapy on bone macroscopy, composition and biomechanical properties after ionizing radiation injury
Radiotherapy used in tumor treatment compromises vascularization of bone tissue. Hyperbaric oxygenation (HBO) increases oxygen availability and improves vascularization, minimizing the deleterious effects of i... (Source: Radiation Oncology)
Source: Radiation Oncology - May 6, 2020 Category: Cancer & Oncology Authors: Luiz Henrique Ferreira J únior, Pedro Henrique Justino Oliveira Limirio, Priscilla Barbosa Ferreira Soares, Paula Dechichi, Letícia de Souza Castro Filice, Paulo Sérgio Quagliatto and Flaviana Soares Rocha Tags: Research Source Type: research

Prognostic impact of the “Sekhar grading system for cranial Chordomas” in patients treated with pencil beam scanning proton therapy: an institutional analysis
Skull base chordomas are rare and heterogeneously behaving tumors. Though still classified as benign they can grow rapidly, are locally aggressive, and have the potential to metastasize. To adapt the treatment... (Source: Radiation Oncology)
Source: Radiation Oncology - May 6, 2020 Category: Cancer & Oncology Authors: Anna-Lena Hottinger, Beat Bojaxhiu, Frank Ahlhelm, Marc Walser, Barbara Bachtiary, Stefan Zepter, Tony Lomax, Alessia Pica and Damien C. Weber Tags: Research Source Type: research

A balanced score to predict survival of elderly patients newly diagnosed with glioblastoma
Over the past years, several treatment regimens have been recommended for elderly patients with glioblastoma (GBM), ranging from ultrahypofractionated radiotherapy (RT) over monochemotherapy (ChT) to combined ... (Source: Radiation Oncology)
Source: Radiation Oncology - May 6, 2020 Category: Cancer & Oncology Authors: Christoph Straube, Kerstin A. Kessel, Stefanie Antoni, Jens Gempt, Bernhard Meyer, Juergen Schlegel, Friederike Schmidt-Graf and Stephanie E. Combs Tags: Research Source Type: research

Feasibility of hippocampus-sparing VMAT for newly diagnosed glioblastoma treated by chemoradiation: pattern of failure analysis
To identify the pattern of failure and oncological safety of hippocampus (HC)-sparing IMRT (HSRT) in newly diagnosed glioblastoma (GBM) patients. (Source: Radiation Oncology)
Source: Radiation Oncology - May 6, 2020 Category: Cancer & Oncology Authors: Chan Woo Wee, Kyung Su Kim, Chae-Yong Kim, Jung Ho Han, Yu Jung Kim and In Ah Kim Tags: Research Source Type: research

Fully automated brain resection cavity delineation for radiation target volume definition in glioblastoma patients using deep learning
We present an automated segmentation method... (Source: Radiation Oncology)
Source: Radiation Oncology - May 6, 2020 Category: Cancer & Oncology Authors: Ekin Ermi ş, Alain Jungo, Robert Poel, Marcela Blatti-Moreno, Raphael Meier, Urspeter Knecht, Daniel M. Aebersold, Michael K. Fix, Peter Manser, Mauricio Reyes and Evelyn Herrmann Tags: Research Source Type: research

Medical physics challenges in clinical MR-guided radiotherapy
The integration of magnetic resonance imaging (MRI) for guidance in external beam radiotherapy has faced significant research and development efforts in recent years. The current availability of linear acceler... (Source: Radiation Oncology)
Source: Radiation Oncology - May 5, 2020 Category: Cancer & Oncology Authors: Christopher Kurz, Giulia Buizza, Guillaume Landry, Florian Kamp, Moritz Rabe, Chiara Paganelli, Guido Baroni, Michael Reiner, Paul J. Keall, Cornelis A. T. van den Berg and Marco Riboldi Tags: Review Source Type: research

Oligometastasis and local ablation in the era of systemic targeted and immunotherapy
During these last years, new agents have dramatically improved the survival of the metastatic patients. Oligometastases represent a continuous field of interest in which the integration of metastases-directed ... (Source: Radiation Oncology)
Source: Radiation Oncology - May 4, 2020 Category: Cancer & Oncology Authors: Rosario Mazzola, Barbara Alicja Jereczek-Fossa, Davide Franceschini, Slavisa Tubin, Andrea Riccardo Filippi, Maria Tolia, Andrea Lancia, Giuseppe Minniti, Stefanie Corradini, Stefano Arcangeli, Marta Scorsetti and Filippo Alongi Tags: Review Source Type: research

Risk factors for esophagitis after hypofractionated palliative (chemo) radiotherapy for non-small cell lung cancer
Esophagitis influences quality of life and might cause treatment interruption and hospitalization. Previous studies of risk factors focused on curative treatment for non-small cell lung cancer (NSCLC), which o... (Source: Radiation Oncology)
Source: Radiation Oncology - May 1, 2020 Category: Cancer & Oncology Authors: Carsten Nieder, Kristian S. Imingen, B ård Mannsåker, Rosalba Yobuta and Ellinor Haukland Tags: Research Source Type: research

The efficacy of positioning stents in preventing Oral complications after head and neck radiotherapy: a systematic literature review
Positioning stent in head and neck radiotherapy seems to have benefit to prevent oral complications but it hasn ’t been summarized by an evidence-based method. (Source: Radiation Oncology)
Source: Radiation Oncology - April 28, 2020 Category: Cancer & Oncology Authors: Dong Chen, Xiaoju Chen, Xinmei Chen, Nanchuan Jiang and Li Jiang Tags: Review Source Type: research

Development and external validation of a nomogram to predict overall survival following stereotactic body radiotherapy for early-stage lung cancer
Prognostication tools for early-stage non-small cell lung cancer (NSCLC) patients treated with stereotactic body radiotherapy (SBRT) are currently lacking. The purpose of this study was to develop and external... (Source: Radiation Oncology)
Source: Radiation Oncology - April 22, 2020 Category: Cancer & Oncology Authors: Sarah Baker, Katerina Bakunina, Marloes Duijm, Mischa S. Hoogeman, Robin Cornelissen, Imogeen Antonisse, John Praag, Wilma D. Heemsbergen and Joost Jan Nuyttens Tags: Research Source Type: research

Recent advances of PET imaging in clinical radiation oncology
Radiotherapy and radiation oncology play a key role in the clinical management of patients suffering from oncological diseases. In clinical routine, anatomic imaging such as contrast-enhanced CT and MRI are wi... (Source: Radiation Oncology)
Source: Radiation Oncology - April 21, 2020 Category: Cancer & Oncology Authors: M. Unterrainer, C. Eze, H. Ilhan, S. Marschner, O. Roengvoraphoj, N. S. Schmidt-Hegemann, F. Walter, W. G. Kunz, P. Munck af Rosensch öld, R. Jeraj, N. L. Albert, A. L. Grosu, M. Niyazi, P. Bartenstein and C. Belka Tags: Review Source Type: research

Magnetic resonance imaging features of tumor and lymph node to predict clinical outcome in node-positive cervical cancer: a retrospective analysis
Current chemoradiation regimens for locally advanced cervical cancer are fairly uniform despite a profound diversity of treatment response and recurrence patterns. The wide range of treatment responses and pro... (Source: Radiation Oncology)
Source: Radiation Oncology - April 20, 2020 Category: Cancer & Oncology Authors: Shin-Hyung Park, Myong Hun Hahm, Bong Kyung Bae, Gun Oh Chong, Shin Young Jeong, Sungdae Na, Sungmoon Jeong and Jae-Chul Kim Tags: Research Source Type: research

Deep convolutional neural networks for automated segmentation of brain metastases trained on clinical data
Deep learning-based algorithms have demonstrated enormous performance in segmentation of medical images. We collected a dataset of multiparametric MRI and contour data acquired for use in radiosurgery, to eval... (Source: Radiation Oncology)
Source: Radiation Oncology - April 20, 2020 Category: Cancer & Oncology Authors: Khaled Bousabarah, Maximilian Ruge, Julia-Sarita Brand, Mauritius Hoevels, Daniel Rue ß, Jan Borggrefe, Nils Große Hokamp, Veerle Visser-Vandewalle, David Maintz, Harald Treuer and Martin Kocher Tags: Research Source Type: research

Combined radiotherapy and concurrent tumor treating fields (TTFields) for glioblastoma: Dosimetric consequences on non-coplanar IMRT as initial results from a phase I trial
Glioblastoma is a rapidly proliferating tumor. Patients bear an inferior prognosis with a median survival time of 14-16  months. Proliferation and repopulation are a major resistance promoting factor for conven... (Source: Radiation Oncology)
Source: Radiation Oncology - April 19, 2020 Category: Cancer & Oncology Authors: N. Guberina, C. P öttgen, S. Kebir, L. Lazaridis, C. Scharmberg, W. Lübcke, M. Niessen, M. Guberina, B. Scheffler, V. Jendrossek, R. Jabbarli, D. Pierscianek, U. Sure, T. Schmidt, C. Oster, P. Hau & hellip; Tags: Research Source Type: research

Quality of life and survival outcome for patients with nasopharyngeal carcinoma treated by volumetric-modulated arc therapy versus intensity-modulated radiotherapy
To evaluate the longitudinal changes of quality of life (QoL) and survival in patients with nasopharyngeal carcinoma (NPC) treated by volumetric-modulated arc therapy (VMAT) versus intensity-modulated radiothe... (Source: Radiation Oncology)
Source: Radiation Oncology - April 19, 2020 Category: Cancer & Oncology Authors: Tai-Lin Huang, Ming-Hsien Tsai, Hui-Ching Chuang, Chih-Yen Chien, Yu-Tsai Lin, Wen-Ling Tsai and Fu-Min Fang Tags: Research Source Type: research

CBCT evaluation of inter- and intra-fraction motions during prostate stereotactic body radiotherapy: a technical note
In most clinical trials, gold fiducial markers are implanted in the prostate to tune the table position before each radiation beam. Yet, it is unclear if a cone-beam computed tomography (CBCT) should be perfor... (Source: Radiation Oncology)
Source: Radiation Oncology - April 19, 2020 Category: Cancer & Oncology Authors: Omar Jmour, Marouan Benna, Pierre Champagnol, Majed Ben Mrad, Anis Hamrouni, Layal Obeid, Chaimaa Lahmamssi, Amal Bousarsar, Nicolas Vial, Amel Rehailia-Blanchard, Sandrine Sotton, Meiling Lan, Julien Langrand-Escure, Alexis Vallard and Nicolas Magn é Tags: Short report Source Type: research

Brain metastases treated with hypofractionated stereotactic radiotherapy: 8 years experience after Cyberknife installation
Hypofractionated stereotactic radiotherapy (HFSRT) is indicated for large brain metastases (BM) or proximity to critical organs (brainstem, chiasm, optic nerves, hippocampus). The primary aim of this study was... (Source: Radiation Oncology)
Source: Radiation Oncology - April 17, 2020 Category: Cancer & Oncology Authors: Laurence Mengue, Aur élie Bertaut, Louise Ngo Mbus, Mélanie Doré, Myriam Ayadi, Karen Clément-Colmou, Line Claude, Christian Carrie, Cécile Laude, Ronan Tanguy, Julie Blanc and Marie-Pierre Sunyach Tags: Research Source Type: research

The value of moderate dose escalation for re-irradiation of recurrent or second primary head-and-neck cancer
Treatment for local and locoregional recurrence or second head-and-neck (H&N) cancers after previous radiotherapy is challenging, and re-irradiation carries a significantly increased risk for radiotherapy-rela... (Source: Radiation Oncology)
Source: Radiation Oncology - April 16, 2020 Category: Cancer & Oncology Authors: Alexander R ühle, Tanja Sprave, Tobias Kalckreuth, Raluca Stoian, Erik Haehl, Constantinos Zamboglou, Roland Laszig, Andreas Knopf, Anca-Ligia Grosu and Nils H. Nicolay Tags: Research Source Type: research

DCE-MRI of locally-advanced carcinoma of the uterine cervix: Tofts analysis versus non-model-based analyses
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) may provide biomarkers of the outcome of locally-advanced cervical carcinoma (LACC). There is, however, no agreement on how DCE-MR recordings shou... (Source: Radiation Oncology)
Source: Radiation Oncology - April 15, 2020 Category: Cancer & Oncology Authors: Kjersti V. Lund, Trude G. Simonsen, Gunnar B. Kristensen and Einar K. Rofstad Tags: Research Source Type: research

Radiotherapeutic management of cervical lymph node metastases from an unknown primary site – experiences from a large cohort treated with modern radiation techniques
To analyze management and outcomes following (chemo)radiation therapy in patients with cervical lymph node metastases from an unknown primary site (CCUP) in a large single-center cohort. (Source: Radiation Oncology)
Source: Radiation Oncology - April 15, 2020 Category: Cancer & Oncology Authors: Tanja Sprave, Alexander R ühle, Katharina Hees, Tobias Kalckreuth, Vivek Verma, Raluca Stoian, Constantinos Zamboglou, Jens Pfeiffer, Roland Laszig, Andreas Knopf, Anca-Ligia Grosu and Nils H. Nicolay Tags: Research Source Type: research

Hippocampal changes in inflammasomes, apoptosis, and MEMRI after radiation-induced brain injury in juvenile rats
The aim of this study was to characterize changes in hippocampal inflammasomes, pyroptosis and apoptosis in juvenile rats after brain irradiation and to assess whether manganese-enhanced magnetic resonance ima... (Source: Radiation Oncology)
Source: Radiation Oncology - April 10, 2020 Category: Cancer & Oncology Authors: Jun Yang, Jingyan Gao, Dan Han, Qinqing Li, Chengde Liao, Jindan Li, Rui Wang and Yueyuan Luo Tags: Research Source Type: research

The role of intraoperative radiation therapy in resectable pancreatic cancer: a systematic review and meta-analysis
Several studies investigating the role of intraoperative radiotherapy (IORT) in the treatment of resectable pancreatic cancer (PC) have been published; however, their results remain inconsistent. By conducting... (Source: Radiation Oncology)
Source: Radiation Oncology - April 9, 2020 Category: Cancer & Oncology Authors: Liang Jin, Ning Shi, Shiye Ruan, Baohua Hou, Yiping Zou, Xiongfeng Zou, Haosheng Jin and Zhixiang Jian Tags: Review Source Type: research

MR-PROTECT: Clinical feasibility of a prostate MRI-only radiotherapy treatment workflow and investigation of acceptance criteria
Retrospective studies on MRI-only radiotherapy have been presented. Widespread clinical implementations of MRI-only workflows are however limited by the absence of guidelines. The MR-PROTECT trial presents an ... (Source: Radiation Oncology)
Source: Radiation Oncology - April 9, 2020 Category: Cancer & Oncology Authors: Emilia Persson, Christian Jamtheim Gustafsson, Petra Ambolt, Silke Engelholm, Sofie Ceberg, Sven B äck, Lars E. Olsson and Adalsteinn Gunnlaugsson Tags: Research Source Type: research