Channel-wise attention enhanced and structural similarity constrained cycleGAN for effective synthetic CT generation from head and neck MRI images
Magnetic resonance imaging (MRI) plays an increasingly important role in radiotherapy, enhancing the accuracy of target and organs at risk delineation, but the absence of electron density information limits it... (Source: Radiation Oncology)
Source: Radiation Oncology - March 14, 2024 Category: Cancer & Oncology Authors: Changfei Gong, Yuling Huang, Mingming Luo, Shunxiang Cao, Xiaochang Gong, Shenggou Ding, Xingxing Yuan, Wenheng Zheng and Yun Zhang Tags: Research Source Type: research
Apparent diffusion coefficient values predict response to brachytherapy in bulky cervical cancer
Diffusion-weighted magnetic resonance imaging (DWI) provides a measurement of tumor cellularity. We evaluated the potential of apparent diffusion coefficient (ADC) values obtained from post-external beam radia... (Source: Radiation Oncology)
Source: Radiation Oncology - March 13, 2024 Category: Cancer & Oncology Authors: Elizabeth E. Dong, Junqian Xu, Joo-Won Kim, Jason Bryan, Jewel Appleton, Daniel A. Hamstra, Michelle S. Ludwig and Alexander N. Hanania Tags: Research Source Type: research
FLASH radiotherapy for the treatment of symptomatic bone metastases in the thorax (FAST-02): protocol for a prospective study of a novel radiotherapy approach
FLASH therapy is a treatment technique in which radiation is delivered at ultra-high dose rates ( ≥ 40 Gy/s). The first-in-human FAST-01 clinical trial demonstrated the clinical feasibility of proton FLASH in the ... (Source: Radiation Oncology)
Source: Radiation Oncology - March 12, 2024 Category: Cancer & Oncology Authors: EC Daugherty, Y Zhang, Z Xiao, AE Mascia, M Sertorio, J Woo, C McCann, KJ Russell, RA Sharma, D Khuntia, JD Bradley, CB Simone 2nd, JC Breneman and JP Perentesis Tags: Research Source Type: research
“sCT-Feasibility” - a feasibility study for deep learning-based MRI-only brain radiotherapy
Radiotherapy (RT) is an important treatment modality for patients with brain malignancies. Traditionally, computed tomography (CT) images are used for RT treatment planning whereas magnetic resonance imaging (... (Source: Radiation Oncology)
Source: Radiation Oncology - March 8, 2024 Category: Cancer & Oncology Authors: Johanna Grigo, Juliane Szkitsak, Daniel H öfler, Rainer Fietkau, Florian Putz and Christoph Bert Tags: Study Protocol Source Type: research
Protocol of a phase II study to evaluate the efficacy and safety of deep-inspiration breath-hold daily online adaptive radiotherapy for centrally located lung tumours (PUDDING study)
Centrally located lung tumours present a challenge because of their tendency to exhibit symptoms such as airway obstruction, atelectasis, and bleeding. Surgical resection of these tumours often requires sacrif... (Source: Radiation Oncology)
Source: Radiation Oncology - March 8, 2024 Category: Cancer & Oncology Authors: Noriko Kishi, Masahiro Yoneyama, Hiroyuki Inoo, Minoru Inoue, Hiraku Iramina, Akiyoshi Nakakura, Tomohiro Ono, Hideaki Hirashima, Takanori Adachi, Norimasa Matsushita, Makoto Sasaki, Takahiro Fujimoto, Mitsuhiro Nakamura, Yukinori Matsuo and Takashi Mizow Tags: Study Protocol Source Type: research
Repeatability quantification of brain diffusion-weighted imaging for future clinical implementation at a low-field MR-linac
Longitudinal assessments of apparent diffusion coefficients (ADCs) derived from diffusion-weighted imaging (DWI) during intracranial radiotherapy at magnetic resonance imaging-guided linear accelerators (MR-li... (Source: Radiation Oncology)
Source: Radiation Oncology - March 6, 2024 Category: Cancer & Oncology Authors: Moritz Rabe, Olaf Dietrich, Robert Forbrig, Maximilian Niyazi, Claus Belka, Stefanie Corradini, Guillaume Landry and Christopher Kurz Tags: Research Source Type: research
Consideration of image guidance in patterns of failure analyses of intensity-modulated radiotherapy for head and neck cancer: a systematic review
Intensity-modulated radiation therapy (IMRT) is considered standard of care for head and neck squamous cell carcinoma (HNSCC). Improved conformity of IMRT and smaller margins, however, have led to concerns of ... (Source: Radiation Oncology)
Source: Radiation Oncology - March 5, 2024 Category: Cancer & Oncology Authors: Paul-Henry Mackeprang, Katarina Bryjova, Astrid E. Heusel, Dominik Henzen, Melissa Scricciolo and Olgun Elicin Tags: Review Source Type: research
High-volume prostate biopsy core involvement is not associated with an increased risk of cancer recurrence following 5-fraction stereotactic body radiation therapy monotherapy
Percentage of positive cores involved on a systemic prostate biopsy has been established as a risk factor for adverse oncologic outcomes and is a National Comprehensive Cancer Network (NCCN) independent parame... (Source: Radiation Oncology)
Source: Radiation Oncology - March 4, 2024 Category: Cancer & Oncology Authors: Jonathan W. Lischalk, Astrid Sanchez, Vianca F. Santos, Christopher Mendez, Meredith Akerman, Todd Carpenter, Moses Tam, David Byun, David R. Wise, Anand Mahadevan, Andrew Evans, William Huang, Aaron Katz, Herbert Lepor and Jonathan A. Haas Tags: Research Source Type: research
Multicenter analysis on the value of standard (chemo)radiotherapy in elderly patients with locally advanced adenocarcinoma of the esophagus or gastroesophageal junction
To assess the tolerability and oncological results of chemoradiation in elderly patients with locally advanced adenocarcinoma of the esophagus or gastroesophageal junction. (Source: Radiation Oncology)
Source: Radiation Oncology - March 4, 2024 Category: Cancer & Oncology Authors: Tilman Bostel, Eirini Nikolaidou, Daniel Wollschl äger, Arnulf Mayer, Justus Kaufmann, Anne Hopprich, Alexander Rühle, Anca-Ligia Grosu, Jürgen Debus, Christian Fottner, Markus Moehler, Peter Grimminger, Heinz Schmidberger and Nils Henrik Nicolay Tags: Research Source Type: research
Contouring practices and artefact management within a synthetic CT-based radiotherapy workflow for the central nervous system
The incorporation of magnetic resonance (MR) imaging in radiotherapy (RT) workflows improves contouring precision, yet it introduces geometrical uncertainties when registered with computed tomography (CT) scan... (Source: Radiation Oncology)
Source: Radiation Oncology - February 29, 2024 Category: Cancer & Oncology Authors: Elia Rossi, Sevgi Emin, Michael Gubanski, Giovanna Gagliardi, Mattias Hedman and Fernanda Villegas Tags: Research Source Type: research
Predictive value of delta radiomics in xerostomia after chemoradiotherapy in patients with stage III-IV nasopharyngeal carcinoma
Xerostomia is one of the most common side effects in nasopharyngeal carcinoma (NPC) patients after chemoradiotherapy. To establish a Delta radiomics model for predicting xerostomia secondary to chemoradiothera... (Source: Radiation Oncology)
Source: Radiation Oncology - February 28, 2024 Category: Cancer & Oncology Authors: Mengze Wang, Yuzhen Xi, Luoyu Wang, Haonan Chen, Feng Jiang and Zhongxiang Ding Tags: Research Source Type: research
Efficacy and safety of thoracic radiotherapy in extensive-stage small-cell lung cancer patients receiving first-line immunotherapy plus chemotherapy: a propensity score matched multicentre retrospective analysis
Platinum-etoposide chemotherapy combined with immune checkpoint inhibitors (ICIs) has been recommended as the first-line standard treatment for extensive-stage small-cell lung cancer (ES-SCLC). However, the ef... (Source: Radiation Oncology)
Source: Radiation Oncology - February 27, 2024 Category: Cancer & Oncology Authors: Yueyuan Yao, Butuo Li, Ruiting Song, Linlin Yang, Bing Zou and Linlin Wang Tags: Research Source Type: research
PLK4 as a potential target to enhance radiosensitivity in triple-negative breast cancer
Radioresistance is one of the barriers to developing more effective therapies against the most aggressive, triple-negative, breast cancer (TNBC) subtype. In our previous studies, we showed that inhibition of P... (Source: Radiation Oncology)
Source: Radiation Oncology - February 16, 2024 Category: Cancer & Oncology Authors: Sierra Pellizzari, Vasudeva Bhat, Harjot Athwal, David W. Cescon, Alison L. Allan and Armen Parsyan Tags: Brief Report Source Type: research
Low rate of severe-end-stage kidney disease after SABR for localised primary kidney cancer
This study aimed to evaluate inci... (Source: Radiation Oncology)
Source: Radiation Oncology - February 15, 2024 Category: Cancer & Oncology Authors: Muhammad Ali, Kendrick Koo, David Chang, Phil Chan, Sheng F. Oon, Daniel Moon, Declan G. Murphy, Renu Eapen, Jeremy Goad, Nathan Lawrentschuk, Arun A. Azad, Sarat Chander, Mark Shaw, Nicholas Hardcastle and Shankar Siva Tags: Research Source Type: research
Interfractional variation in whole-breast VMAT irradiation: a dosimetric study with complementary SGRT and CBCT patient setup
The dosimetric effect of setup uncertainty and tissue deformations in left-sided whole-breast irradiation with complementary surface-guided radiotherapy (SGRT) and cone-beam computed tomography (CBCT) setup wa... (Source: Radiation Oncology)
Source: Radiation Oncology - February 13, 2024 Category: Cancer & Oncology Authors: M. Mankinen, T. Vir én, J. Seppälä and T. Koivumäki Tags: Research Source Type: research
