IMPT of head and neck cancer: unsupervised machine learning treatment planning strategy for reducing radiation dermatitis
In this study, do... (Source: Radiation Oncology)
Source: Radiation Oncology - January 14, 2023 Category: Cancer & Oncology Authors: Noufal Manthala Padannayil, Dayananda Shamurailatpam Sharma, Sapna Nangia, Kartikeshwar C. Patro, Utpal Gaikwad and Nagarjuna Burela Tags: Research Source Type: research

Radiation-induced senescence: therapeutic opportunities
The limitation of cancer radiotherapy does not derive from an inability to ablate tumor, but rather to do so without excessively damaging critical tissues and organs and adversely affecting patient ’s quality o... (Source: Radiation Oncology)
Source: Radiation Oncology - January 13, 2023 Category: Cancer & Oncology Authors: Jae Ho Kim, Stephen L. Brown and Marcia N. Gordon Tags: Review Source Type: research

Geometric and dosimetric consequences of intra-fractional movement in single isocenter non-coplanar stereotactic radiosurgery
To investigate the geometric and dosimetric impacts of intra-fractional movement for patients with single or multiple brain metastasis treated using Varian Hyperarc ™ mono-isocentric radiosurgery. (Source: Radiation Oncology)
Source: Radiation Oncology - January 11, 2023 Category: Cancer & Oncology Authors: Nelson Tsz Cheong Fung, Wai Lung Wong, Michael Chi Hang Lee, Elki Sze Nga Cheung and Philip Yuguang Wu Tags: Research Source Type: research

Dosimetric quality of HyperArc in boost radiotherapy for single glioblastoma: comparison with CyberKnife and manual VMAT
Stereotactic radiotherapy (SRT) and hypo-fractionated radiotherapy are feasible treatment options for single glioblastoma multiforme when combined with conventional radiotherapy or delivered alone. HyperArc (H... (Source: Radiation Oncology)
Source: Radiation Oncology - January 10, 2023 Category: Cancer & Oncology Authors: Mingyuan Pan, Wenqian Xu, Lei Sun, Chaozhuang Wang, Shengnan Dong, Yun Guan, Jun Yang and Enmin Wang Tags: Research Source Type: research

Acute toxicities and cumulative dose to the brain of repeated sessions of stereotactic radiotherapy (SRT) for brain metastases: a retrospective study of 184 patients
Stereotactic radiation therapy (SRT) is a focal treatment for brain metastases (BMs); thus, 20 to 40% of patients will require salvage treatment after an initial SRT session, either because of local or distant... (Source: Radiation Oncology)
Source: Radiation Oncology - January 10, 2023 Category: Cancer & Oncology Authors: L. Kuntz, C. Le F èvre, D. Jarnet, A. Keller, P. Meyer, A. Thiery, H. Cebula, G. Noel and D. Antoni Tags: Research Source Type: research

Health-related quality of life and patient-reported symptoms after postoperative proton beam radiotherapy of cervical and endometrial cancer: 2-year results of the prospective phase II APROVE-trial
The APROVE-trial investigated the tolerability of postoperative proton beam therapy in women with cervical or endometrial cancer. The present analysis evaluated the secondary endpoints of health-related qualit... (Source: Radiation Oncology)
Source: Radiation Oncology - January 9, 2023 Category: Cancer & Oncology Authors: Eva Meixner, Antje Wark, Tobias Forster, Fabian Weykamp, Kristin Lang, Laila K önig, Katja Lindel, Jan Tobias Oelmann-Avendano, Johannes Krisam, Andreas Schneeweiss, Malte Ellerbrock, Thomas Mielke, Juliane Hörner-Rieber, Klaus Herfarth, Jürgen Debus a Tags: Research Source Type: research

CT ventilation image-guided helical Tomotherapy at sparing functional lungs for locally advanced lung cancer: analysis of dose-function metrics and the impact on pulmonary toxicity
CT ventilation image (CTVI)-guided radiotherapy that selectively avoids irradiating highly-functional lung regions has potential to reduce pulmonary toxicity. Considering Helical TomoTherapy (HT) has higher mo... (Source: Radiation Oncology)
Source: Radiation Oncology - January 9, 2023 Category: Cancer & Oncology Authors: Shuangshuang Li, Juan Liu, Shanbao Gao, Yicai Yin, Ling Zhang, Yongchao Han, Xishun Zhang, Yuanyuan Li, Jing Yan and Zhen Hou Tags: Research Source Type: research

Mesorectal motion evaluation in rectal cancer MR-guided radiotherapy: an exploratory study to quantify treatment margins
Mesorectal motion (MM) is a source of uncertainty during neoadjuvant chemoradiotherapy (nCRT) delivery for locally advanced rectal cancer (LARC). Previously published experiences using cone-beam computed tomog... (Source: Radiation Oncology)
Source: Radiation Oncology - January 6, 2023 Category: Cancer & Oncology Authors: Luca Boldrini, Giuditta Chiloiro, Davide Cusumano, Angela Romano, Lorenzo Placidi, Gabriele Turco, Marco Valerio Antonelli, Matteo Nardini, Matteo Galetto, Luca Indovina and Maria Antonietta Gambacorta Tags: Research Source Type: research

Dosimetric comparison of deformable image registration and synthetic CT generation based on CBCT images for organs at risk in cervical cancer radiotherapy
Anatomical variations existing in cervical cancer radiotherapy treatment can be monitored by cone-beam computed tomography (CBCT) images. Deformable image registration (DIR) from planning CT (pCT) to CBCT imag... (Source: Radiation Oncology)
Source: Radiation Oncology - January 5, 2023 Category: Cancer & Oncology Authors: Yankui Chang, Yongguang Liang, Bo Yang, Jie Qiu, Xi Pei and Xie George Xu Tags: Research Source Type: research

Cochlear sparing in LINAC-based radiosurgery for vestibular schwannoma: a dosimetric comparison of dynamic conformal arc, IMRT and VMAT treatment plans
Stereotactic radiosurgery (SRS) is the preferred treatment for vestibular schwannoma (VS) in patients with preserved hearing and tumour diameter (Source: Radiation Oncology)
Source: Radiation Oncology - January 4, 2023 Category: Cancer & Oncology Authors: Jeremy Khong, Ramkumar Govindaraj, Daniel Ramm, Suzanne Edwards and Daniel Roos Tags: Research Source Type: research

Hyaluronic acid spacer in prostate cancer radiotherapy: dosimetric effects, spacer stability and long-term toxicity and PRO in a phase II study
Perirectal spacers may be beneficial to reduce rectal side effects from radiotherapy (RT). Here, we present the impact of a hyaluronic acid (HA) perirectal spacer on rectal dose as well as spacer stability, lo... (Source: Radiation Oncology)
Source: Radiation Oncology - January 2, 2023 Category: Cancer & Oncology Authors: Ulrika Bj öreland, Kristina Notstam, Per Fransson, Karin Söderkvist, Lars Beckman, Joakim Jonsson, Tufve Nyholm, Anders Widmark and Camilla Thellenberg Karlsson Tags: Research Source Type: research

Calibration and evaluation of the relative biological effectiveness for carbon-ion radiotherapy in a new relative to a clinically applied treatment planning system
The study objective was to validate the relative biological effectiveness (RBE) in RayStation for carbon-ion radiotherapy (CIRT) using the Syngo treatment planning system as reference. (Source: Radiation Oncology)
Source: Radiation Oncology - December 31, 2022 Category: Cancer & Oncology Authors: Weiwei Wang, Zhijie Huang, Wei Sun, Xufei Wang, Jingfang Zhao and Hao Shen Tags: Research Source Type: research

A review of radiomics and genomics applications in cancers: the way towards precision medicine
The application of radiogenomics in oncology has great prospects in precision medicine. Radiogenomics combines large volumes of radiomic features from medical digital images, genetic data from high-throughput ... (Source: Radiation Oncology)
Source: Radiation Oncology - December 30, 2022 Category: Cancer & Oncology Authors: Simin Li and Baosen Zhou Tags: Review Source Type: research

Safety and efficacy of paclitaxel plus carboplatin versus paclitaxel plus cisplatin in neoadjuvant chemoradiotherapy for patients with locally advanced esophageal carcinoma: a retrospective study
We evaluated and compared the efficacy and safety of chemotherapy with paclitaxel plus cisplatin (TP) or carboplatin (TC) in patients with locally advanced esophageal squamous cell carcinoma (LA-ESCC) who unde... (Source: Radiation Oncology)
Source: Radiation Oncology - December 30, 2022 Category: Cancer & Oncology Authors: Li Jiang, Jie Zhu, Xue Chen, Yi Wang, Lei Wu, Gang Wan, Yongtao Han, Xuefeng Leng, Lin Peng and Qifeng Wang Tags: Research Source Type: research

Feasibility of linac-based fractionated stereotactic radiotherapy and stereotactic radiosurgery for patients with up to ten brain metastases
Linac-based fractionated stereotactic radiotherapy (fSRT) and stereotactic radiosurgery (SRS) are increasingly being used to manage patients with multiple metastases. This retrospective cohort study aimed to c... (Source: Radiation Oncology)
Source: Radiation Oncology - December 28, 2022 Category: Cancer & Oncology Authors: Masanori Hirata, Kazuaki Yasui, Naofumi Oota, Hirofumi Ogawa, Tsuyoshi Onoe, Sayo Maki, Yusuke Ito, Kenji Hayashi, Hirofumi Asakura, Shigeyuki Murayama, Koichi Mitsuya, Shoichi Deguchi, Katsumasa Nakamura, Nakamasa Hayashi, Tetsuo Nishimura and Hideyuki H Tags: Research Source Type: research