Clinical implementation of magnetic resonance imaging simulation for radiation oncology planning: 5 year experience
This report details the clinical implementation of an MR simulation (MR-planning) program for external beam radiotherapy (... (Source: Radiation Oncology)
Source: Radiation Oncology - February 7, 2023 Category: Cancer & Oncology Authors: Daniel Moore-Palhares, Ling Ho, Lin Lu, Brige Chugh, Danny Vesprini, Irene Karam, Hany Soliman, Sean Symons, Eric Leung, Andrew Loblaw, Sten Myrehaug, Greg Stanisz, Arjun Sahgal and Gregory J. Czarnota Tags: Research Source Type: research

Radiosurgery of limited brain metastases from primary solid tumor: results of the randomized phase III trial (NCT02355613) comparing treatments executed with a specialized or a C-arm linac-based platform
Comparative prospective data regarding different radiosurgery (SRS) modalities for treating brain metastases (BMs) from solid tumors are not available. To investigate with a single institute phase III randomiz... (Source: Radiation Oncology)
Source: Radiation Oncology - February 7, 2023 Category: Cancer & Oncology Authors: Marta Scorsetti, Pierina Navarria, Luca Cozzi, Elena Clerici, Luisa Bellu, Davide Franceschini, Antonio Marco Marzo, Ciro Franzese, Valter Torri, Giacomo Reggiori, Francesca Lobefalo, Luca Raspagliesi, Luca Attuati, Federico Pessina, Andrea Franzini, Pier Tags: Research Source Type: research

Clinical utility of combined assessments of 4D volumetric perfusion CT, diffusion-weighted MRI and 18F-FDG PET-CT for the prediction of outcomes of head and neck squamous cell carcinoma treated with chemoradiotherapy
Multiparametric imaging has been seen as a route to improved prediction of chemoradiotherapy treatment outcomes. Four-dimensional volumetric perfusion CT (4D PCT) is useful for whole-organ perfusion measuremen... (Source: Radiation Oncology)
Source: Radiation Oncology - February 6, 2023 Category: Cancer & Oncology Authors: Hirokazu Tsuchiya, Munetaka Matoba, Yuka Nishino, Kiyotaka Ota, Mariko Doai, Hiroji Nagata and Hiroyuki Tuji Tags: Research Source Type: research

Dosimetric comparison of two dose expansion methods in intensity modulated radiotherapy for breast cancer
To explore the dosimetric difference between IMRT-VB plan based on the establishment of external expansion structure and virtual bolus (VB) and IMRT-SF based on the skin flash (SF) tool of the Eclipse treatmen... (Source: Radiation Oncology)
Source: Radiation Oncology - February 4, 2023 Category: Cancer & Oncology Authors: Ran Tang, Aimin Li, Yingjing Li, Guanhua Deng, Yufeng Wang, Qing Xiao, Luosheng Zhang and Yue Luo Tags: Research Source Type: research

Effects of whole-brain radiation therapy on the blood –brain barrier in immunocompetent and immunocompromised mouse models
Approximately 20% of all cancer patients will develop brain metastases in their lifespan. The standard of care for patients with multiple brain metastases is whole-brain radiation therapy, which disrupts the b... (Source: Radiation Oncology)
Source: Radiation Oncology - February 3, 2023 Category: Cancer & Oncology Authors: K. E. Blethen, S. A. Sprowls, T. A. Arsiwala, C. P. Wolford, D. M. Panchal, R. A. Fladeland, M. J. Glass, L. P. Dykstra, B. N. Kielkowski, J. R. Blackburn, C. J. Andrick and P. R. Lockman Tags: Research Source Type: research

A review of diffusion-weighted magnetic resonance imaging in head and neck cancer patients for treatment evaluation and prediction of radiation-induced xerostomia
The incidence of head and neck cancers (HNC) is rising worldwide especially with HPV-related oropharynx squamous cell carcinoma. The standard of care for the majority of patients with locally advanced pharynge... (Source: Radiation Oncology)
Source: Radiation Oncology - January 30, 2023 Category: Cancer & Oncology Authors: Tai Ermongkonchai, Richard Khor, Morikatsu Wada, Eddie Lau, Daniel Tao Xing and Sweet Ping Ng Tags: Review Source Type: research

Changes in the characteristics of patients treated for brain metastases with repeat stereotactic radiotherapy (SRT): a retrospective study of 184 patients
Brain metastases (BMs) are the leading cause of intracranial malignant neoplasms in adults. WHO, Karnofsky performance status (KPS), age, number of BMs, extracerebral progression (ECP), recursive partitioning ... (Source: Radiation Oncology)
Source: Radiation Oncology - January 30, 2023 Category: Cancer & Oncology Authors: L. Kuntz, C. Le F èvre, D. Jarnet, A. Keller, P. Meyer, A. Thiery, H. Cebula, G. Noel and D. Antoni Tags: Research Source Type: research

G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells
The gene of the Epidermal growth factor receptor (EGFR) is one of the most frequently altered genes in glioblastoma (GBM), with deletions of exons 2 –7 (EGFRvIII) being amongst the most common genomic mutations. E... (Source: Radiation Oncology)
Source: Radiation Oncology - January 29, 2023 Category: Cancer & Oncology Authors: Meryem H. Cetin, Thorsten Rieckmann, Konstantin Hoffer, Britta Riepen, Sabrina Christiansen, Fruzsina Gatzemeier, Simon Feyerabend, Melanie Schoof, Ulrich Sch üller, Cordula Petersen, Martin Mynarek, Kai Rothkamm, Malte Kriegs and Nina Struve Tags: Research Source Type: research

Efficacy and toxicity of Iodine-125 seed implantation for lymph node recurrence secondary to esophageal cancer after radiotherapy: a multicenter retrospective study
This multicenter study aimed to explore the efficacy and toxicity of radioactive Iodine-125 seed implantation for lymph node recurrence in patients with esophageal cancer after external radiotherapy. (Source: Radiation Oncology)
Source: Radiation Oncology - January 26, 2023 Category: Cancer & Oncology Authors: Lirong Wu, Xinxin Zhao, Suqing Tian, Kaixian Zhang, Chuang He, Yong Feng, Jiawei Zhou, Wenjie Guo, Zhe Ji, Xia He, Guanglie Chen and Junjie Wang Tags: Research Source Type: research

Real world practice of postoperative radiotherapy for patients with completely resected pIIIA-N2 non-small cell lung cancer: a national survey of radiation oncologists in China
Results from Lung ART and PORT-C trials suggest that postoperative radiotherapy (PORT) cannot routinely be recommended as standard treatment in completely resected pIIIA-N2 NSCLC patients, but their effects on... (Source: Radiation Oncology)
Source: Radiation Oncology - January 25, 2023 Category: Cancer & Oncology Authors: Shujie Zhou, Yirui Zhai, Kaikai Zhao, Yu Men, Xiangjiao Meng and Zhouguang Hui Tags: Research Source Type: research

Observation of the delineation of the target volume of radiotherapy in adult-type diffuse gliomas after temozolomide-based chemoradiotherapy: analysis of recurrence patterns and predictive factors
Radiation therapy is the cornerstone of treatment for adult-type diffuse gliomas, but recurrences are inevitable. Our study assessed the prognosis and recurrence pattern of different radiotherapy volumes after... (Source: Radiation Oncology)
Source: Radiation Oncology - January 23, 2023 Category: Cancer & Oncology Authors: Hongbo Liu, Lu Zhang, Ye Tan, Yanxia Jiang and Haijun Lu Tags: Research Source Type: research

Proposed prognostic subgroups and facilitated clinical decision-making for additional locoregional radiotherapy in de novo metastatic nasopharyngeal carcinoma: a retrospective study based on recursive partitioning analysis
The high heterogeneity of de novo metastatic nasopharyngeal carcinoma (dmNPC) makes its prognosis and treatment challenging. We aimed to accurately stage dmNPC and assess the patterns of treatment strategies f... (Source: Radiation Oncology)
Source: Radiation Oncology - January 21, 2023 Category: Cancer & Oncology Authors: Yuyi Yao, Xuesong Sun, Huageng Huang, Zhao Wang, Xiaojie Fang, Meiting Chen, Zegeng Chen, Huawei Weng, Chengcheng Guo, Huangming Hong, He Huang and Tongyu Lin Tags: Research Source Type: research

Quality evaluation of guidelines for the diagnosis and treatment of radiation enteritis
To systematically evaluate the guidelines for the diagnosis and treatment of radioactive enteritis, compare their differences and reasons and provide some reference for updating them. (Source: Radiation Oncology)
Source: Radiation Oncology - January 20, 2023 Category: Cancer & Oncology Authors: Xiao-Feng Yang, Meng-Yao Zheng, Li-Ya An, Jin-Min Sun, Qian-Wen Hei, Yan-Hong Ji, Da-Li Sun and Hai-Yu He Tags: Review Source Type: research

The relationship between the radiation dose of pelvic-bone marrow and lymphocytic toxicity in concurrent chemoradiotherapy for cervical cancer
The purpose of this study is to verify the correlation between medium and low radiation doses of the pelvic-bone marrow and the incidence of lymphocytic toxicity during concurrent chemoradiotherapy for cervica... (Source: Radiation Oncology)
Source: Radiation Oncology - January 20, 2023 Category: Cancer & Oncology Authors: Bao-Zhong Zhang, Yang Li, Li-Ming Xu, Yan-Lan Chai, Chao Qu, Yuan-Jie Cao, Jing Wang, Hai-Ling Hou and Jiaqi Zhang Tags: Research Source Type: research

Monte Carlo dosimetry of the 60Co sources of a new GZP3 HDR afterloading system
The purpose of this work was to obtain the dosimetric parameters of the new GZP3 60Co high-dose-rate afterloading system launched by the Nuclear Power Institute of China, which is comprised of two different 60Co ... (Source: Radiation Oncology)
Source: Radiation Oncology - January 20, 2023 Category: Cancer & Oncology Authors: Junxiang Wu, Shengwei Kang, Pei Wang, Jie Li and Xianliang Wang Tags: Research Source Type: research