Quality assurance in a phase III, multicenter, randomized trial of POstmastectomy radioThErapy in Node posiTive breast cancer with or without Internal mAmmary nodaL irradiation (POTENTIAL): a planning benchmark case
To report the planning benchmark case results of the POTENTIAL trial —a multicenter, randomized, phase 3 trial—to evaluate the value of internal mammary nodal (IMN) irradiation for patients with high-risk breas... (Source: Radiation Oncology)
Source: Radiation Oncology - November 29, 2023 Category: Cancer & Oncology Authors: Yu-Chun Song, Zhi-Hui Hu, Xue-Na Yan, Hui Fang, Yu Tang, Hao Jing, Kuo Men, Na Zhang, Jun Zhang, Jing Jin, Qiu-Zi Zhong, Jun Ma, Wei-Fang Yang, Ya-Hua Zhong, Li-Hua Dong, Xiao-Hong Wang & hellip; Tags: Research Source Type: research

A prospective single-arm study on the relationship between dose-volume parameters of pelvic functional bone marrow and acute hematological toxicities during intensity-modulated radiotherapy with or without concurrent chemotherapy for uterine cervical/endometrial cancer
FLT-PET/CT can accurately identify and locate functional bone marrow (FBM) with hematopoietic capability, the FBM were divided into two levels as FBM1 (strongest hemopoietic ability region)and FBM2 (moderate hemo... (Source: Radiation Oncology)
Source: Radiation Oncology - November 27, 2023 Category: Cancer & Oncology Authors: Hongbo Chen, Qian Zhong, Yujie Liu, Jinyan Li, Wenjing Deng, Jie Wang, Shuquan Zhou, Zengrong Yu, Xianzhan Huang, Yuanqiong Huang, Bo Zhen, Jihong Wei, Weijian Zhang, Xiaohong Ruan and Lin Xiao Tags: Research Source Type: research

Pretreatment patient-specific quality assurance prediction based on 1D complexity metrics and 3D planning dose: classification, gamma passing rates, and DVH metrics
Highly modulated radiotherapy plans aim to achieve target conformality and spare organs at risk, but the high complexity of the plan may increase the uncertainty of treatment. Thus, patient-specific quality as... (Source: Radiation Oncology)
Source: Radiation Oncology - November 20, 2023 Category: Cancer & Oncology Authors: Liyuan Chen, Huanli Luo, Shi Li, Xia Tan, Bin Feng, Xin Yang, Ying Wang and Fu Jin Tags: Research Source Type: research

Proton therapy (PT) combined with concurrent chemotherapy for locally advanced non-small cell lung cancer with negative driver genes
To discuss the optimal treatment modality for inoperable locally advanced Non-Small Cell Lung Cancer patients with poor physical status, impaired cardio-pulmonary function, and negative driver genes, and provi... (Source: Radiation Oncology)
Source: Radiation Oncology - November 16, 2023 Category: Cancer & Oncology Authors: Yonglong Jin, Shosei Shimizu, Yinuo Li, Yuan Yao, Xiguang Liu, Hongzong Si, Hideyuki Sakurai and Wenjing Xiao Tags: Research Source Type: research

Failure patterns of locoregional recurrence after reducing target volumes in patients with nasopharyngeal carcinoma receiving adaptive replanning during intensity-modulated radiotherapy: a single-center experience in China
Previous researches have demonstrated that adaptive replanning during intensity-modulated radiation therapy (IMRT) could enhance the prognosis of patients with nasopharyngeal carcinoma (NPC). However, the deli... (Source: Radiation Oncology)
Source: Radiation Oncology - November 16, 2023 Category: Cancer & Oncology Authors: Xiate Zhou, Jian Zhu, Chao Zhou, Wei Wang, Weijun Ding, Meng Chen, Kuifei Chen, Shuling Li, Xiaofeng Chen and Haihua Yang Tags: Research Source Type: research

Evaluation of a novel CBCT conversion method implemented in a treatment planning system
To evaluate a novel CBCT conversion algorithm for dose calculation implemented in a research version of a treatment planning system (TPS). (Source: Radiation Oncology)
Source: Radiation Oncology - November 16, 2023 Category: Cancer & Oncology Authors: Wolfgang Lechner, D ávid Kanalas, Sarah Haupt, Lukas Zimmermann and Dietmar Georg Tags: Research Source Type: research

Use of focal radiotherapy boost for prostate cancer: radiation oncologists ’ perspectives and perceived barriers to implementation
In a recent phase III randomized control trial, delivering a focal radiotherapy (RT) boost to tumors visible on MRI was shown to improve disease-free survival and regional/distant metastasis-free survival for ... (Source: Radiation Oncology)
Source: Radiation Oncology - November 11, 2023 Category: Cancer & Oncology Authors: Allison Y. Zhong, Asona J. Lui, Matthew S. Katz, Alejandro Berlin, Sophia C. Kamran, Amar U. Kishan, Vedang Murthy, Himanshu Nagar, Daniel Seible, Bradley J. Stish, Alison C. Tree and Tyler M. Seibert Tags: Research Source Type: research

First clinical application of image-guided intraoperative electron radiation therapy with real time intraoperative dose calculation in recurrent rectal cancer: technical procedure
We report the first abdomino-pelvic application of an image-guided intraoperative el... (Source: Radiation Oncology)
Source: Radiation Oncology - November 10, 2023 Category: Cancer & Oncology Authors: Falk Roeder, Gerd Fastner, Christoph Fussl, Felix Sedlmayer, Markus Stana, Johannes Berchtold, Tarkan J äger, Jaroslav Presl, Philipp Schredl, Klaus Emmanuel, Daniela Colleselli, Gabriel Kotolacsi, Philipp Scherer, Philipp Steininger and Christoph Gaisbe Tags: Research Source Type: research

Noninvasive cardiac radioablation for ventricular tachycardia: dosimetric comparison between linear accelerator- and robotic CyberKnife-based radiosurgery systems
Few dosimetric comparisons have been published between linear accelerator (LA)-based systems and CyberKnife (CK)-based robotic radiosurgery systems for cardiac radio-ablation in ventricular tachycardia. This s... (Source: Radiation Oncology)
Source: Radiation Oncology - November 10, 2023 Category: Cancer & Oncology Authors: Ching-Yu Wang, Li-Ting Ho, Lian-Yu Lin, Hsing-Min Chan, Hung-Yi Chen, Tung-Lin Yu, Yu-Sen Huang, Sung-Hsin Kuo, Wen-Jeng Lee and Jenny Ling-Yu Chen Tags: Research Source Type: research

Dose escalation for stereotactic arrhythmia radioablation of recurrent ventricular tachyarrhythmia - a phase II clinical trial
Stereotactic arrhythmia radioablation (STAR) is delivered with a planning target volume (PTV) prescription dose of 25 Gy, mostly to the surrounding 75 –85% isodose line. This means that the average and maximum ... (Source: Radiation Oncology)
Source: Radiation Oncology - November 8, 2023 Category: Cancer & Oncology Authors: Boldizsar Kovacs, Michael Mayinger, Stefanie Ehrbar, Debra Fesslmeier, Maiwand Ahmadsei, Lorraine Sazgary, Robert Manka, Hatem Alkadhi, Frank Ruschitzka, Firat Duru, Alexandros Papachristofilou, Christian Sticherling, Slawomir Blamek, Krzysztof S. Go łba Tags: Study Protocol Source Type: research

Hypoxic tumor cell-derived small extracellular vesicle miR-152-3p promotes cervical cancer radioresistance through KLF15 protein
Radiotherapy is widely used in treating cervical cancer patients, however, radioresistance unavoidably occurs and seriously affects the treatment effect. It is well known that hypoxia plays an important role i... (Source: Radiation Oncology)
Source: Radiation Oncology - November 7, 2023 Category: Cancer & Oncology Authors: Junying Zhou, Ningjing Lei, Wanjia Tian, Ruixia Guo, Feng Gao, Hanlin Fu, Jing Zhang, Shiliang Dong, Mengyu Chen, Qian Ma, Yong Li and Lei Chang Tags: Research Source Type: research

Correction: Treatment outcomes of stereotactic body radiation therapy for primary and metastatic sarcoma of the spine
(Source: Radiation Oncology)
Source: Radiation Oncology - November 7, 2023 Category: Cancer & Oncology Authors: Eunji Kim, Mi-Sook Kim, Eun Kyung Paik, Ung-Kyu Chang and Chang-Bae Kong Tags: Correction Source Type: research

Comprehensive evaluation of similarity between synthetic and real CT images for nasopharyngeal carcinoma
Although magnetic resonance imaging (MRI)-to-computed tomography (CT) synthesis studies based on deep learning have significantly progressed, the similarity between synthetic CT (sCT) and real CT (rCT) has onl... (Source: Radiation Oncology)
Source: Radiation Oncology - November 7, 2023 Category: Cancer & Oncology Authors: Siqi Yuan, Xinyuan Chen, Yuxiang Liu, Ji Zhu, Kuo Men and Jianrong Dai Tags: Research Source Type: research

Comparison of adverse events in partial- or whole breast radiotherapy: investigation of cosmesis, toxicities and quality of life in a meta-analysis of randomized trials
Adjuvant whole breast radiotherapy and systemic therapy are part of the current evidence-based treatment protocols for early breast cancer, after breast-conserving surgery. Numerous randomized trials have inve... (Source: Radiation Oncology)
Source: Radiation Oncology - November 2, 2023 Category: Cancer & Oncology Authors: Jan Haussmann, Wilfried Budach, Stefanie Corradini, David Krug, Danny Jazmati, B álint Tamaskovics, Edwin Bölke, Alessia Pedotoa, Kai Kammers and Christiane Matuschek Tags: Research Source Type: research

Development of a novel delivery quality assurance system based on simultaneous verification of dose distribution and binary multi-leaf collimator opening in helical tomotherapy
Intensity-modulated radiation therapy (IMRT) requires delivery quality assurance (DQA) to ensure treatment accuracy and safety. Irradiation techniques such as helical tomotherapy (HT) have become increasingly ... (Source: Radiation Oncology)
Source: Radiation Oncology - November 2, 2023 Category: Cancer & Oncology Authors: Yuichi Tanaka, Masatoshi Hashimoto, Minoru Ishigami, Masahiro Nakano and Tomoyuki Hasegawa Tags: Research Source Type: research