Review of brachytherapy clinical trials: a cross-sectional analysis of ClinicalTrials.gov
Characterizing the landscape of clinical trials including brachytherapy can provide an overview of the current status and research trends which may guide further areas of investigation. (Source: Radiation Oncology)
Source: Radiation Oncology - February 13, 2024 Category: Cancer & Oncology Authors: David Chen, Rod Parsa, Kabir Chauhan, Jelena Lukovic, Kathy Han, Amandeep Taggar and Srinivas Raman Tags: Research Source Type: research
A 4D-CBCT correction network based on contrastive learning for dose calculation in lung cancer
This study aimed to present a deep-learning network called contrastive learning-based cycle generative adversarial networks (CLCGAN) to mitigate streak artifacts and correct the CT value in four-dimensional co... (Source: Radiation Oncology)
Source: Radiation Oncology - February 9, 2024 Category: Cancer & Oncology Authors: Nannan Cao, Ziyi Wang, Jiangyi Ding, Heng Zhang, Sai Zhang, Liugang Gao, Jiawei Sun, Kai Xie and Xinye Ni Tags: Research Source Type: research
Dosimetric evaluation of LINAC-based single-isocenter multi-target multi-fraction stereotactic radiosurgery with more than 20 targets: comparing MME, HyperArc, and RapidArc
To compare the dosimetric quality of three widely used techniques for LINAC-based single-isocenter multi-target multi-fraction stereotactic radiosurgery (fSRS) with more than 20 targets: dynamic conformal arc ... (Source: Radiation Oncology)
Source: Radiation Oncology - February 7, 2024 Category: Cancer & Oncology Authors: Hyunuk Jung, Jihyung Yoon, Olga Dona Lemus, Sean Tanny, Yuwei Zhou, Michael Milano, Kenneth Usuki, Sara Hardy and Dandan Zheng Tags: Research Source Type: research
Quantitative analysis of the impact of respiratory state on the heartbeat-induced movements of the heart and its substructures
This study seeks to examine the influence of the heartbeat on the position, volume, and shape of the heart and its substructures during various breathing states. The findings of this study will serve as a valu... (Source: Radiation Oncology)
Source: Radiation Oncology - February 5, 2024 Category: Cancer & Oncology Authors: Benzhe Liang, Guanzhong Gong, Ying Tong, Lizhen Wang, Ya Su, Huadong Wang, Zhenkai Li, Hongyu Yan, Xiaohong Zhang and Yong Yin Tags: Research Source Type: research
Toxicity of external beam accelerated partial-breast irradiation (APBI) in adjuvant therapy of early-stage breast cancer: prospective randomized study
Accelerated partial breast irradiation (APBI) is an alternative breast-conserving therapy approach where radiation is delivered in less time compared to whole breast irradiation (WBI), resulting in improved pa... (Source: Radiation Oncology)
Source: Radiation Oncology - February 3, 2024 Category: Cancer & Oncology Authors: Petr Burkon, Iveta Selingerova, Marek Slavik, Milos Holanek, Miroslav Vrzal, Oldrich Coufal, Katerina Polachova, Petr Muller, Pavel Slampa and Tomas Kazda Tags: Research Source Type: research
Combining a noble gas with radiotherapy: glutamate receptor antagonist xenon may act as a radiosensitizer in glioblastoma
Ionotropic glutamate receptors α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) and N-methyl-D-aspartate receptor (NMDAR) modulate proliferation, invasion and radioresistance in glioblast... (Source: Radiation Oncology)
Source: Radiation Oncology - January 30, 2024 Category: Cancer & Oncology Authors: Thomas B üttner, Marielena K. E. Maerevoet, Frank A. Giordano, Marlon R. Veldwijk, Carsten Herskind and Arne Mathias Ruder Tags: Research Source Type: research
Monte Carlo simulation of the Varian TrueBeam flattened-filtered beams using a surrogate geometry in PRIMO
Monte Carlo simulation of radiation transport for medical linear accelerators (linacs) requires accurate knowledge of the geometrical description of the linac head. Since the geometry of Varian TrueBeam machin... (Source: Radiation Oncology)
Source: Radiation Oncology - January 25, 2024 Category: Cancer & Oncology Authors: Miguel Rodriguez, Josep Sempau and Lorenzo Brualla Tags: Research Source Type: research
Generation of tissues outside the field of view (FOV) of radiation therapy simulation imaging based on machine learning and patient body outline (PBO)
It is not unusual to see some parts of tissues are excluded in the field of view of CT simulation images. A typical mitigation is to avoid beams entering the missing body parts at the cost of sub-optimal plann... (Source: Radiation Oncology)
Source: Radiation Oncology - January 25, 2024 Category: Cancer & Oncology Authors: Sunmi Kim, Lulin Yuan, Siyong Kim and Tae Suk Suh Tags: Research Source Type: research
Cone beam CT-based adaptive intensity modulated proton therapy assessment using automated planning for head-and-neck cancer
To assess the feasibility of CBCT-based adaptive intensity modulated proton therapy (IMPT) using automated planning for treatment of head and neck (HN) cancers. (Source: Radiation Oncology)
Source: Radiation Oncology - January 23, 2024 Category: Cancer & Oncology Authors: Yihang Xu, William Jin, Michael Butkus, Mariluz De Ornelas, Jonathan Cyriac, Matthew T. Studenski, Kyle Padgett, Garrett Simpson, Stuart Samuels, Michael Samuels and Nesrin Dogan Tags: Research Source Type: research
A PET/CT radiomics model for predicting distant metastasis in early-stage non –small cell lung cancer patients treated with stereotactic body radiotherapy: a multicentric study
This study ... (Source: Radiation Oncology)
Source: Radiation Oncology - January 22, 2024 Category: Cancer & Oncology Authors: Lu Yu, Zhen Zhang, HeQing Yi, Jin Wang, Junyi Li, Xiaofeng Wang, Hui Bai, Hong Ge, Xiaoli Zheng, Jianjiao Ni, Haoran Qi, Yong Guan, Wengui Xu, Zhengfei Zhu, Ligang Xing, Andre Dekker & hellip; Tags: Research Source Type: research
ALA-RDT in GBM: protocol of the phase I/II dose escalation trial of radiodynamic therapy with 5-Aminolevulinic acid in patients with recurrent glioblastoma
Despite improvements in surgical as well as adjuvant therapies over the last decades, the prognosis for patients with glioblastoma remains poor. Five-Aminolevulinic acid (5-ALA) induced porphyrins are already ... (Source: Radiation Oncology)
Source: Radiation Oncology - January 22, 2024 Category: Cancer & Oncology Authors: Niklas Benedikt Pepper, Hans Theodor Eich, Michael M üther, Michael Oertel, Stephan Rehn, Dorothee Cäcilia Spille and Walter Stummer Tags: Study Protocol Source Type: research
Development and validation of survival prognostic models for head and neck cancer patients using machine learning and dosiomics and CT radiomics features: a multicentric study
This study aimed to investigate the value of clinical, radiomic features extracted from gross tumor volumes (GTVs) delineated on CT images, dose distributions (Dosiomics), and fusion of CT and dose distributio... (Source: Radiation Oncology)
Source: Radiation Oncology - January 22, 2024 Category: Cancer & Oncology Authors: Zahra Mansouri, Yazdan Salimi, Mehdi Amini, Ghasem Hajianfar, Mehrdad Oveisi, Isaac Shiri and Habib Zaidi Tags: Research Source Type: research
Evolution of radiation-induced temporal lobe injury after intensity-modulated radiation therapy in nasopharyngeal carcinoma: a large cohort retrospective study
Previous studies have demonstrated conflicting findings regarding the initial MRI patterns of radiotherapy-induced temporal lobe injury (RTLI) and the evolution of different RTLI patterns. The aim of this stud... (Source: Radiation Oncology)
Source: Radiation Oncology - January 19, 2024 Category: Cancer & Oncology Authors: Jing Hou, Yun He, Handong Li, Zhaodong Ai, Qiang Lu, Biao Zeng, Chuanmiao Xie and Xiaoping Yu Tags: Research Source Type: research
Is radiotherapy necessary for upper rectal cancer underwent curative resection? A retrospective study of 363 patients
To investigate the impact of radiotherapy (RT) on recurrence and survival in patients with locally advanced upper rectal cancer underwent curative resection. (Source: Radiation Oncology)
Source: Radiation Oncology - January 18, 2024 Category: Cancer & Oncology Authors: Zhiwei Ma, Jumei Zhou, Ke Liu, Sisi Chen, Qinghui Wu, Lin Peng, Wei Zhao and Suyu Zhu Tags: Research Source Type: research
The radiation- and chemo-sensitizing capacity of diclofenac can be predicted by a decreased lactate metabolism and stress response
An enhanced aerobic glycolysis ( “Warburg effect”) associated with an increase in lactic acid in the tumor microenvironment contributes to tumor aggressiveness and resistance to radiation and chemotherapy. We i... (Source: Radiation Oncology)
Source: Radiation Oncology - January 16, 2024 Category: Cancer & Oncology Authors: Melissa Schwab, Ali Bashiri Dezfouli, Mohammad Khosravi, Bayan Alkotub, Lisa Bauer, Mohammad Javed Tahmasebi Birgani and Gabriele Multhoff Tags: Case Report Source Type: research
