Physical functional capacity assessment in children with chronic kidney disease: A cross sectional observational study
CONCLUSION: Muscle strength and functional capacity were most impaired in Indian children on hemodialysis and best preserved in KTR.PMID:38629745 | DOI:10.5414/CN111295 (Source: Clinical Nephrology)
Source: Clinical Nephrology - April 17, 2024 Category: Urology & Nephrology Authors: Himani Goswami Harda Shah Kinnari Vala Shahenaz Kapadia Bharat Tiwari Anshuman Saha Source Type: research
Isotopic evidence of autochthonous organic matter acting as a major sink of anthropogenic heavy metals in modern lacustrine sediments
Environ Pollut. 2024 Apr 15:123964. doi: 10.1016/j.envpol.2024.123964. Online ahead of print.ABSTRACTThe knowledge of major sources, sinks, and the burial fate of various pollutants added to modern aquatic ecosystems under changing environmental conditions is limited but crucial for our sustainability. In this context, the spatial distributions and causative factors of organic matter (OM) and heavy metal accumulations have been explored in modern lacustrine sediments of a large urbanized and protected wetland (ULB: Upper Lake Bhopal) in Central India. For this purpose, geochemical properties, in particular, stable isotopes...
Source: Environmental Pollution - April 17, 2024 Category: Environmental Health Authors: Nafees Ahmad Satinder Pal Singh Shivam Sahu Rohan Bhattacharyya Abhayanand Singh Maurya Nitish Kumar Rakesh Kumar Rout Gyana Ranjan Tripathy Source Type: research
A Dicopper(II)-Based Carbonic Anhydrase Model - Quantum-Chemical Evaluation of the Mechanistic Pathway
Angew Chem Int Ed Engl. 2024 Apr 17:e202319530. doi: 10.1002/anie.202319530. Online ahead of print.ABSTRACTThe cyanobacterium Prochloron didemni, an obligate symbiont of different species of colonial ascidians, occurring in the Pacific and Indian Oceans, produces a variety of cyclic peptides. These patellamide-type macrocycles lead to relatively stable dicopper(II) complexes that are extremely efficient carbonic anhydrase mimics, the most active model systems known so far. Importantly, it recently was shown that copper(II) is coordinated to patellamide derivatives in Prochloron cells. An interesting question therefore is, ...
Source: Angewandte Chemie - April 17, 2024 Category: Chemistry Authors: Peter Comba Gunasekaran Velmurugan Philipp Baur Source Type: research
Overview of U.S. COVID-19 vaccine safety surveillance systems
This report describes the U.S. government's COVID-19 vaccine safety monitoring systems and programs used by the Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the Department of Defense, the Department of Veterans Affairs, and the Indian Health Service. Using the adverse event of myocarditis following mRNA COVID-19 vaccination as a model, we demonstrate how the multiple, complementary monitoring systems worked to rapidly detect, assess, and verify a vaccine safety signal. In addition, longer-term follow-up was conducted to evaluate the recovery status of myocarditis cases following vaccin...
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Julianne Gee Tom T Shimabukuro John R Su David Shay Margaret Ryan Sridhar V Basavaraju Karen R Broder Matthew Clark C Buddy Creech Francesca Cunningham Kristin Goddard Harrison Guy Kathryn M Edwards Richard Forshee Tanya Hamburger Anne M Hause Nicola P Kl Source Type: research
Drug Repositioning: A Monetary Stratagem to Discover a New Application of Drugs
Curr Drug Discov Technol. 2024;21(1):e101023222023. doi: 10.2174/0115701638253929230922115127.ABSTRACTDrug repurposing, also referred to as drug repositioning or drug reprofiling, is a scientific approach to the detection of any new application for an already approved or investigational drug. It is a useful policy for the invention and development of new pharmacological or therapeutic applications of different drugs. The strategy has been known to offer numerous advantages over developing a completely novel drug for certain problems. Drug repurposing has numerous methodologies that can be categorized as target-oriented, dr...
Source: Current Drug Discovery Technologies - April 17, 2024 Category: Drugs & Pharmacology Authors: Ankur Rohilla Seema Rohilla Source Type: research
Purification and Characterization of Desferrioxamine B of Pseudomonas fluorescens and Its Application to Improve Oil Content, Nutrient Uptake, and Plant Growth in Peanuts
Microb Ecol. 2024 Apr 17;87(1):60. doi: 10.1007/s00248-024-02377-0.ABSTRACTMicroorganisms produce siderophores, which are low-molecular-weight iron chelators when iron availability is limited. The present analyzed the role of LNPF1 as multifarious PGPR for improving growth parameters and nutrient content in peanut and soil nutrients. Such multifarious PGPR strains can be used as effective bioinoculants for peanut farming. In this work, rhizosphere bacteria from Zea mays and Arachis hypogaea plants in the Salem area of Tamil Nadu, India, were isolated and tested for biochemical attributes and characteristics that stimulate ...
Source: Microbial Ecology - April 17, 2024 Category: Microbiology Authors: S Nithyapriya Lalitha Sundaram Sakthi Uma Devi Eswaran Kahkashan Perveen Najla A Alshaikh R Z Sayyed Andrea Mastinu Source Type: research
Ecotourism or ecological concerns? Tracing the impact of economic policy uncertainty and natural resources on tourism-driven ecological footprints
This study applies a novel dynamic ARDL simulation approach for long-run and short-run analyses. The study also employs frequency-domain causality to check the causal relationship between the variables. The result reveals that tourism has a positive effect on the ecological footprint. Similarly, economic policy uncertainty has a positive and significant effect on the ecological footprint in India during the sample period. Additionally, natural resource rent shows a positive effect on the ecological footprint or deteriorating environmental quality in the short and long run in the sample period. However, renewable energy con...
Source: Environmental Science and Pollution Research International - April 17, 2024 Category: Environmental Health Authors: Malayaranjan Sahoo Patita Paban Mohanty Shreyasee Kaushik Muhummad Khairul Islam Lisma Rourt Source Type: research
A Dicopper(II)-Based Carbonic Anhydrase Model - Quantum-Chemical Evaluation of the Mechanistic Pathway
Angew Chem Int Ed Engl. 2024 Apr 17:e202319530. doi: 10.1002/anie.202319530. Online ahead of print.ABSTRACTThe cyanobacterium Prochloron didemni, an obligate symbiont of different species of colonial ascidians, occurring in the Pacific and Indian Oceans, produces a variety of cyclic peptides. These patellamide-type macrocycles lead to relatively stable dicopper(II) complexes that are extremely efficient carbonic anhydrase mimics, the most active model systems known so far. Importantly, it recently was shown that copper(II) is coordinated to patellamide derivatives in Prochloron cells. An interesting question therefore is, ...
Source: Angewandte Chemie - April 17, 2024 Category: Chemistry Authors: Peter Comba Gunasekaran Velmurugan Philipp Baur Source Type: research
Analysis of donor morbidity in 177 donor hepatectomies for living donor liver transplant: Experience from a high-volume centre in western India
ConclusionDonor safety (outcome) is determined by meticulous donor surgery and good-quality remnant.Graphical abstract (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 17, 2024 Category: Gastroenterology Source Type: research
Prediction of mortality from hepatitis A virus-related acute liver failure in children —Do we have the perfect prognostic model?
(Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 17, 2024 Category: Gastroenterology Source Type: research
Analyzing global research trends and focal points in the utilization of laser techniques for the treatment of urolithiasis from 1978 to 2022: visualization and bibliometric analysis
We examined 962 publications that met the specified criteria, 791 (82.22%) of which were original articles. The analysis of the retrieved publications indicated a consistent increase in research output from 1978 to 2022; a particularly noteworthy surge occurred after 2003. In particular, the U.S. claimed the leading position as the most productive co untry, contributing 211 articles (21.93%). However, India had the highest research productivity according to the adjustment index of 19.08. In the European region, 324 publications (33.68% of the total) originated from 25 countries. The Journal of Endourology contributed the m...
Source: Urolithiasis - April 17, 2024 Category: Urology & Nephrology Source Type: research
Mapping malaria vectors and insecticide resistance in a high-endemic district of Haryana, India: implications for vector control strategies
Achieving effective control and elimination of malaria in endemic regions necessitates a comprehensive understanding of local mosquito species responsible for malaria transmission and their susceptibility to i... (Source: Malaria Journal)
Source: Malaria Journal - April 17, 2024 Category: Infectious Diseases Authors: Gaurav Kumar, Sanjeev Gupta, Jaspreet Kaur, Shweta Pasi, Rajendra Baharia, Ajeet Kumar Mohanty, Pawan Goel, Amit Sharma and Manju Rahi Tags: Research Source Type: research
Analyzing global research trends and focal points in the utilization of laser techniques for the treatment of urolithiasis from 1978 to 2022: visualization and bibliometric analysis
We examined 962 publications that met the specified criteria, 791 (82.22%) of which were original articles. The analysis of the retrieved publications indicated a consistent increase in research output from 1978 to 2022; a particularly noteworthy surge occurred after 2003. In particular, the U.S. claimed the leading position as the most productive co untry, contributing 211 articles (21.93%). However, India had the highest research productivity according to the adjustment index of 19.08. In the European region, 324 publications (33.68% of the total) originated from 25 countries. The Journal of Endourology contributed the m...
Source: Urolithiasis - April 17, 2024 Category: Urology & Nephrology Source Type: research
The Impact of Post-Birth Timing on OAE Test Efficacy: An Observational Analysis of Neonatal Hearing Screening
This study evaluates the efficacy of OAE screenings within the first five days after birth to determine the most effective timing. An observational study involved 1,013 full-term neonates at a tertiary care centre. These neonates underwent Transient Evoked Otoacoustic Emissions (TEOAE) screenings daily from Day 1 to Day 5, following WHO and JCIH guidelines. The study assessed pass rates, false positives, and false negatives, with follow-up screenings at one and three months for neonates with initial ambiguous results. The study found that screening efficiency significantly increased, with Day 1 pass rates at 8% (81 neonate...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 17, 2024 Category: ENT & OMF Source Type: research
Prediction of deleterious non-synonymous SNPs of human MDC1 gene: an in silico approach
Volume 70, Issue 1, December 2024, Page 101-112 . (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - April 17, 2024 Category: Sexual Medicine Authors: Vaishnavee ThoteSusha DineshSameer SharmaDepartment of Bioinformatics, BioNome, Bengaluru, India Source Type: research
