Chemsex and risk of sexually transmitted infections: a perspective from India
Introduction Chemsex, also called as party and play or intensive sex partying, is the intentional use of psychoactive drugs before or during sex, mostly by gay and bisexual men having sex with men (GBMSM) to enable, enhance and prolong sexual interaction.1 The practice is now becoming increasingly common among heterosexual individuals too.1 Various chemsex drugs have been described (table 1), the principal three that are commonly used include mephedrone, gamma-hydroxybutyrate/gamma-butyrolactone (GHB/GBL) and crystallised methamphetamine.1 The injectable use of these substances for similar purpose is called as slamming or ...
Source: Sexually Transmitted Infections - April 18, 2024 Category: Sexual Medicine Authors: Juyal, D., Pal, S., Joshi, C., Dhawan, N., Rawre, J., Dhawan, B. Tags: Education Source Type: research
Serous cystic neoplasm of pancreas with surgical obstructive jaundice and double duct sign: Cystadenoma or cystadenocarcinoma?
(Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 18, 2024 Category: Gastroenterology Source Type: research
Evolution of Oral Contraceptive Pills
(Source: The Journal of Obstetrics and Gynecology of India)
Source: The Journal of Obstetrics and Gynecology of India - April 18, 2024 Category: OBGYN Source Type: research
ERJ Podcast April 2024: Allergic bronchopulmonary aspergillosis
As part of the April issue, the European Respiratory Journal presents the latest in its series of podcasts. Chief Editor James Chalmers interviews Ritesh Agarwal (Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India) about the revised International Society for Human and Animal Mycology ABPA working group clinical practice guidelines for diagnosing, classifying and treating allergic bronchopulmonary aspergillosis/mycoses. (Source: European Respiratory Journal)
Source: European Respiratory Journal - April 18, 2024 Category: Respiratory Medicine Tags: Podcast Source Type: research
The Promise of a Longer Lifetime
Modern hygiene has been described as the reaction against the old fatalistic creed that deaths inevitably occur at a constant rate. The study of vital statistics shows that there is no “iron law of mortality.” According to a report prepared for the National Conservation Commission fifteen years ago, statistics for India showed that the average duration of life there was less than twenty-five years. In Sweden it was over fifty years; in Massachusetts, forty-five years. The leng th of life is increasing wherever sanitary science and preventive medicine are applied. In India it is stationary. In Europe it doubled in three...
Source: JAMA - Journal of the American Medical Association - April 18, 2024 Category: General Medicine Source Type: research
Role of Imaging in Predicting the Deep Surgical Margin in Gingivobuccal Complex Cancers: A Pilot Study
AbstractCancers arising from the gingivobuccal complex are one of the most common types of cancer in the oral cavity and are associated with poor prognosis. Among the various prognostic factors, positive surgical margin is the most important one that can be controlled by the operating surgeon. The deep surgical margins for buccal mucosa cancers is normally assessed by palpating the skin for induration and skin pinchability. The present study evaluates the role of imaging in assessing the deep surgical margin and its efficacy for skin preservation in buccal mucosa/ gingivobuccal carcinomas. The patients of gingivobuccal com...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research
To Study the Pre Operative Indicators of Incudal Necrosis in Tubo-Tympanic Chronic Otitis Media
In this study, it was observed that the presence of granulations over the perforation margins, disease persisting for more than 10 years, moderate to moderately severe hearing loss appear to be significant reliable indicators of incudal necrosis in tubo-tympanic type of CSOM. All patients of tubo-tympanic type of CSOM should be assessed in detail so as to reach early diagnosis of ossicular erosion that helps in surgical decision making and preparedness regarding ossiculoplasty and patient consent. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research
The Combined Impact of Curcumin: Piperine and Sorafenib on microRNAs and Different Pathways in Breast Cancer Cells
This study suggests that the combination of sorafenib and curcumin: piperine can combat breast cancer by modulating several microRNAs and signaling pathways involved in the development and progression of breast cancer. (Source: Indian Journal of Clinical Biochemistry)
Source: Indian Journal of Clinical Biochemistry - April 18, 2024 Category: Biochemistry Source Type: research
Molecules, Vol. 29, Pages 1846: Sandalwood Oils of Different Origins Are Active In Vitro against Madurella mycetomatis, the Major Fungal Pathogen Responsible for Eumycetoma
i A. Khalid
In the search for new bioactive agents against the infectious pathogen responsible for the neglected tropical disease (NTD) mycetoma, we tested a collection of 27 essential oils (EOs) in vitro against Madurella mycetomatis, the primary pathogen responsible for the fungal form of mycetoma, termed eumycetoma. Among this series, the EO of Santalum album (Santalaceae), i.e., East Indian sandalwood oil, stood out prominently with the most potent inhibition in vitro. We, therefore, directed our research toward 15 EOs of Santalum species of different geographical origins, along with two samples of EOs from other p...
Source: Molecules - April 18, 2024 Category: Chemistry Authors: Shereen O. Abd Algaffar Stephan Seegers Prabodh Satyal William N. Setzer Thomas J. Schmidt Sami A. Khalid Tags: Article Source Type: research
Association between Body Mass Index (BMI) and Waist Circumference with Leg Power in Cricketers
Cricket is one of the most well-known sports played in India. It not only comprises of aerobic activity but also includes complex-based movements like running, jumping, diving, catching, etc that depend on various individual factors such as height, weight, power, endurance, agility etc. (Source: Journal of Bodywork and Movement Therapies)
Source: Journal of Bodywork and Movement Therapies - April 18, 2024 Category: Physiotherapy Authors: Aishwarya Chorge, Titiksha Pol Source Type: research
IJERPH, Vol. 21, Pages 496: The Relationship between All-Cause Dementia and Acute Diabetes Complications among American Indian and Alaska Native Peoples
Conclusions: AI/AN diabetes patients with dementia suffered from considerably higher rates of acute diabetes complications than their counterparts without dementia. The clinical management of patients with comorbid diabetes and dementia is particularly challenging and may require individualized treatment approaches. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - April 18, 2024 Category: Environmental Health Authors: Xiaoyi Niu Jenny Chang Maria M. Corrada Ann Bullock Blythe Winchester Spero M. Manson Joan O ’Connell Luohua Jiang Tags: Article Source Type: research
Physical functional capacity assessment in children with chronic kidney disease: A cross sectional observational study
CONCLUSION: Muscle strength and functional capacity were most impaired in Indian children on hemodialysis and best preserved in KTR.PMID:38629745 | DOI:10.5414/CN111295 (Source: Clinical Nephrology)
Source: Clinical Nephrology - April 17, 2024 Category: Urology & Nephrology Authors: Himani Goswami Harda Shah Kinnari Vala Shahenaz Kapadia Bharat Tiwari Anshuman Saha Source Type: research
Drug Repositioning: A Monetary Stratagem to Discover a New Application of Drugs
Curr Drug Discov Technol. 2024;21(1):e101023222023. doi: 10.2174/0115701638253929230922115127.ABSTRACTDrug repurposing, also referred to as drug repositioning or drug reprofiling, is a scientific approach to the detection of any new application for an already approved or investigational drug. It is a useful policy for the invention and development of new pharmacological or therapeutic applications of different drugs. The strategy has been known to offer numerous advantages over developing a completely novel drug for certain problems. Drug repurposing has numerous methodologies that can be categorized as target-oriented, dr...
Source: Current Drug Discovery Technologies - April 17, 2024 Category: Drugs & Pharmacology Authors: Ankur Rohilla Seema Rohilla Source Type: research
Overview of U.S. COVID-19 vaccine safety surveillance systems
This report describes the U.S. government's COVID-19 vaccine safety monitoring systems and programs used by the Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the Department of Defense, the Department of Veterans Affairs, and the Indian Health Service. Using the adverse event of myocarditis following mRNA COVID-19 vaccination as a model, we demonstrate how the multiple, complementary monitoring systems worked to rapidly detect, assess, and verify a vaccine safety signal. In addition, longer-term follow-up was conducted to evaluate the recovery status of myocarditis cases following vaccin...
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Julianne Gee Tom T Shimabukuro John R Su David Shay Margaret Ryan Sridhar V Basavaraju Karen R Broder Matthew Clark C Buddy Creech Francesca Cunningham Kristin Goddard Harrison Guy Kathryn M Edwards Richard Forshee Tanya Hamburger Anne M Hause Nicola P Kl Source Type: research
Ecotourism or ecological concerns? Tracing the impact of economic policy uncertainty and natural resources on tourism-driven ecological footprints
This study applies a novel dynamic ARDL simulation approach for long-run and short-run analyses. The study also employs frequency-domain causality to check the causal relationship between the variables. The result reveals that tourism has a positive effect on the ecological footprint. Similarly, economic policy uncertainty has a positive and significant effect on the ecological footprint in India during the sample period. Additionally, natural resource rent shows a positive effect on the ecological footprint or deteriorating environmental quality in the short and long run in the sample period. However, renewable energy con...
Source: Environmental Science and Pollution Research International - April 17, 2024 Category: Environmental Health Authors: Malayaranjan Sahoo Patita Paban Mohanty Shreyasee Kaushik Muhummad Khairul Islam Lisma Rourt Source Type: research
