Triclonal Gammopathy in Multiple Myeloma with Bleeding Diathesis: A Case Report
ConclusionIn plasma cell dyscrasias and lymphoproliferative diseases, monoclonal gammopathies are often observed, while the biclonal variety is less frequent. However, tri clonal gammopathy having a combination of IgM Kappa, IgG Kappa, and IgA Lambda is extremely rare and their clinical significance is unknown. (Source: Indian Journal of Clinical Biochemistry)
Source: Indian Journal of Clinical Biochemistry - April 22, 2024 Category: Biochemistry Source Type: research
Microplastics and associated polycyclic aromatic hydrocarbons in surface water and sediment of the Bay of Bengal coastal area, India: sources, pathway and ecological risk
AbstractIn the aquatic environment around the world, microplastic contamination has been a common and ongoing issue. Particularly, the ability of microplastics to absorb persistent organic pollutants (POPs) and then transmit these POPs to aquatic creatures has attracted a lot of interest. A stereomicroscope was used to detect the size, shape, and color of the microplastics (MPs), and Fourier Transform Infrared (FTIR) spectroscopy was used to identify the polymer composition of the MPs. To address MP transit, destiny, and mitigation, a study of MP pollution coastal areas is required. In the current study, MP pollution in th...
Source: Environmental Geochemistry and Health - April 22, 2024 Category: Environmental Health Source Type: research
Tympanoplasty can be Concurrent with Adenoidectomy. Tube Factor Assessment
AbstractTo assess changes in middle ear pressures following adenotonsillectomies in children, and to evaluate the possibility of performing tympanoplasty at the same surgical time. Prospective study in which tube function was assessed using tympanometry on the first postoperative day and on the seventh postoperative day after adenotonsillectomies. A total of 39 children aged 6.8 ± 2.6 years were evaluated. On the first postoperative day, 79.5% presented with changes in middle ear pressure. On the seventh postoperative day, only 12.8% maintained this change. Tube dysfunction following adenotonsillectomy is transient a...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 22, 2024 Category: ENT & OMF Source Type: research
The Effect of Platelet-Rich Plasma on the Healing of Nasal Mucosa After Surgery of the Nose: A Randomized Clinical Trial
ConclusionOur study detects the potential hopeful effect of PRP on postoperative wound healing of nasal mucosa, dryness, and nasal crustations. According to these results, the application of PRP post-nasal surgery can be considered an effective method for maintaining post-nasal surgery Mucosa. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 22, 2024 Category: ENT & OMF Source Type: research
Short Report of Retained Radiopaque Marker in Gauze and Comparison of Ease of Dislodging and Breaking
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - April 22, 2024 Category: Cancer & Oncology Source Type: research
Burseraceae in the Latest Cretaceous of India: Sahniocarpon Chitaley & Patil
International Journal of Plant Sciences, Ahead of Print. (Source: International Journal of Plant Sciences)
Source: International Journal of Plant Sciences - April 22, 2024 Category: Biology Authors: Steven R. Manchester Dashrath K. Kapgate Walter S. Judd Source Type: research
The future of neurosurgery in India: challenges and opportunities for early career researchers
(Source: Neurosurgical Review)
Source: Neurosurgical Review - April 22, 2024 Category: Neurosurgery Source Type: research
Genes, Vol. 15, Pages 522: HLA-B and C Expression Contributes to COVID-19 Disease Severity within a South African Cohort
suran
Globally, SARS-CoV-2 has negatively impacted many lives and industries due to its rapid spread, severe outcomes, and the need for the implementation of lockdown strategies across the world. SARS-CoV-2 disease severity varies among different populations. Host genetics have been associated with various diseases, and their ability to alter disease susceptibility and severity. In addition, Human Leukocyte Antigen (HLA) expression levels and alleles vary significantly among ethnic groups, which might impact the host’s response to SARS-CoV-2. Our previous study highlighted that HLA-A might have an effect ...
Source: Genes - April 22, 2024 Category: Genetics & Stem Cells Authors: Lisa Naidoo Thilona Arumugam Veron Ramsuran Tags: Article Source Type: research
Exploring psychiatric patient restraints: Balancing safety, ethics, and patient rights in mental healthcare
Asian J Psychiatr. 2024 Apr 15;96:104051. doi: 10.1016/j.ajp.2024.104051. Online ahead of print.ABSTRACTRestraint, often linked with limiting an individual's freedom of movement, has become a focal point of extensive discussion and evaluation within the realm of mental healthcare. Striking a delicate balance between ensuring individual safety and minimizing reliance on restraint methods poses a significant challenge. In mental health inpatient settings, the prevalent forms of restraint encompass physical, chemical, environmental, and psychological methods. Paradoxically, the consequences of employing restraint can be sever...
Source: Asian Journal of Psychiatry - April 21, 2024 Category: Psychiatry Authors: Fayaz Ahmad Paul Aasim Ur Rehman Ganie Danishwar Rasool Dar Priyanka Saikia Indrajeet Banerjee Source Type: research
Role of non-receptor tyrosine kinases in epilepsy: significance and potential as therapeutic targets
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - April 21, 2024 Category: Drugs & Pharmacology Authors: Ozasvi R. ShankerSonali KumarJyotirmoy BanerjeeManjari TripathiP. Sarat ChandraAparna Banerjee Dixita Dr. B.R. Ambedkar Centre for Biomedical Research (ACBR), University of Delhi, New Delhi, Indiab Department of Biophysics, All India Institute of Medical Source Type: research
Impact of Epley ’s Manoeuvre on Quality of Life in Patients with Posterior Semicircular Canal Benign Paroxysmal Positional Vertigo: A Pre- and Post-Treatment Analysis
This study assesses the effectiveness of Epley ’s manoeuvre in improving QoL in patients with PSC–BPPV. This prospective analytical study, conducted at a tertiary care centre from January 2021 to December 2022, included 93 adult patients diagnosed with PSC–BPPV via the Dix–Hallpike test. Participants were evaluated using the dizziness ha ndicap inventory (DHI) and visual vertigo analogue score (VAS) at baseline and on days 3, 10, and 30 post-treatments with Epley’s manoeuvre. Data analysis focused on changes in DHI and VAS scores to assess the impact of treatment. The cohort comprised 58.1% males and 41.9% female...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 21, 2024 Category: ENT & OMF Source Type: research
Exploring Micronutrient Dynamics in COVID-19 Severity and Mortality: Unraveling the Roles of Vitamin D, Calcium, Phosphorus, Magnesium and ALP
This study explores the impact of Vitamin D, calcium, phosphorus, magnesium, and alkaline phosphatase (ALP) on COVID-19 severity and mortality. The study involves 200 participants (100 COVID-19 patients, 100 controls), we meticulously analyzed micronutrient dynamics. Calcium, phosphorus, magnesium and ALP was measured spectrophotometrically. Vitamin D was measured using Chemiluminescent method. The study reveals that diminished levels of calcium, phosphorus, magnesium, and with elevated ALP, are significantly associated with COVID-19 cases. Whereas the Vitamin D levels in severe group was increased when compared to mild ca...
Source: Indian Journal of Clinical Biochemistry - April 21, 2024 Category: Biochemistry Source Type: research
Are Healthcare Professionals Adequately Trained for Safe Blood Transfusions? Targeted Training to Bridge Knowledge Gaps
ConclusionThis study demonstrates that the evaluation of knowledge should be carried out on a continuous manner in order to detect gaps in the professional sector and to ensure the effectiveness of training through well-targeted educational programs. (Source: Indian Journal of Hematology and Blood Transfusion)
Source: Indian Journal of Hematology and Blood Transfusion - April 20, 2024 Category: Hematology Source Type: research
Clinical Profile, Treatment and Outcome of Thrombotic Thrombocytopenia Purpura (TTP) in Rituximab Era- an Experience from Tertiary Care Centre from North India
AbstractThrombotic thrombocytopenic purpura (TTP) is a microangiopathic hemolytic anemia (MAHA) resulting from severe deficiency of ADAMTS13. TTP is an acute medical emergency which requires early treatment with therapeutic plasma exchange. With the early use of Rituximab along with PLEX, early response is achieved and relapse rate has gone down. There is lack of published data from India regarding treatment and outcome of TTP. We retrospectively analyzed our data of 21 patients of TTP including 4 patients who had TA-TMA. TTP patients were treated with TPE, pulse methylprednisolone and rituximab. After a median follow up o...
Source: Indian Journal of Hematology and Blood Transfusion - April 20, 2024 Category: Hematology Source Type: research
A Case Report of Therapeutic Plasma Exchange in Hypertriglyceridemia-Induced Pancreatitis
AbstractTo support the evidence of plasma exchange ’s ability to rapidly lower serum TG levels and provide upcoming research opportunities for evaluating the long-term effects of this treatment, we present the case of a 35-year-old female who was admitted for Hypertriglyceridemia-induced Pancreatitis (HTGP). She underwent Therapeutic Plasma Excha nge (TPE) using Spectra Optia Apheresis System on an emergency basis. The patient had a remarkable reduction of serum Triglycerides (TG) from 3953 to 291 mg/dl, which was life saving. On subsequent follow-up the serum TG levels remained constant post-TPE with conservative trea...
Source: Indian Journal of Hematology and Blood Transfusion - April 20, 2024 Category: Hematology Source Type: research
