Clinical Approach to Neuroendocrine Neoplasm Associated With Ovarian Teratoma
ConclusionsThe prognosis and clinical behavior of NETs associated with ovarian teratomas are good with long progression-free survival. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - November 30, 2021 Category: Endocrinology Source Type: research
Pediatric gynecology: ovarian teratomas in children
Conclusion: This research found several information deficits in the database of pediatric ovarian teratoma. This subject, overall, has not been fully researched especially with regards to, this cancer and patient population, which require further research. [Ethiop. J. Health Dev. 2021; 35(3):227-233]Keywords: Ovarian teratoma, Ovarian neoplasm, Gynecology, Pediatrics (Source: Ethiopian Journal of Health Development)
Source: Ethiopian Journal of Health Development - November 25, 2021 Category: African Health Authors: Pang Xinqin, Qiu Zihong , Xu Shucui Source Type: research
A Rare Case of Immature Sacrococcygeal Teratoma With Lymph Node Metastasis in a Neonate
This is the first report of an immature sacrococcygeal teratoma with inguinal lymph node metastasis, providing the histologic transformation of an immature teratoma in association with chemotherapy. Incomplete tumor resection with coccygectomy was performed, and the histopathologic diagnosis was a grade 3 immature teratoma. Following the initial surgery, the residual tumors enlarged and the tumors metastasized to the inguinal lymph node, demonstrating immature teratoma without yolk sac tumor components. Although the tumor markers normalized after chemotherapy, the residual tumors had enlarged significantly. Therefore, a co...
Source: Journal of Pediatric Hematology Oncology - October 30, 2021 Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research
Fetal Oropharyngeal Teratoma: A Case Report
AbstractOropharyngeal teratomas are extremely rare fetal tumors and originate from pluripotent stem cells. The tumor typically arises from the palato-pharyngeal region around the basishenoid. These tumors are heterogenous in nature. The reported case was diagnosed at 20 weeks gestation. Ultrasound revealed a heterogenous, lobulated facial mass protruded from the oral cavity without any hypervascularity or intracranial extension. There was no evidence of polyhydromnios. After counseling, the parents opted for termination of pregnancy. Histopathological examination from the exophytic mass was consistent with immature ...
Source: Journal of Fetal Medicine - October 8, 2021 Category: Perinatology & Neonatology Source Type: research
ASO Author Reflections: Ovarian Cystectomy for Apparent Early-Stage Pure Immature Ovarian Teratomas
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - September 24, 2021 Category: Cancer & Oncology Source Type: research
Mediastinal Germ Cell Tumors: A Review and Update on Pathologic, Clinical, and Molecular Features
Mediastinal germ cell tumors (MGCTs) are the most common extragonadal germ cell tumors (GCTs) and most often arise in the anterior mediastinum with a male predilection. MGCTs also have a predilection for patients with Klinefelter syndrome and possibly other genetic conditions. MGCTs, as GCTs at other extragonadal sites, are thought to arise from germ cells improperly retained during migration along the midline during embryogenesis. Similar to their counterparts in the testes, MGCTs are classified into seminomatous and nonseminomatous GCTs. Seminomatous MGCT represents pure seminoma, whereas nonseminomatous MGCTs encompass ...
Source: Advances in Anatomic Pathology - August 20, 2021 Category: Pathology Tags: Review Articles Source Type: research
SALL-4 and Beta-Catenin Expression in Sinonasal Teratocarcinosarcoma
AbstractSinonasal teratocarcinosarcoma (SNTCS) is a rare, aggressive malignancy that displays a heterogeneous combination of malignant blastema-like, epithelial and mesenchymal components. Its exact histogenesis is unknown with hypotheses ranging from true germ cell derivation to origin from pluripotent stem cells. However, despite this tumor ’s multiphenotypic histology, which includes frequent glandular, squamous, and neuroectodermal differentiation similar to adnexal germ cell tumors, SNTCS appears to have some differences from adnexal teratomas. For example, unlike adnexal teratomas, SNTCS has never been described as...
Source: Head and Neck Pathology - June 9, 2021 Category: Pathology Source Type: research
Response to letter entitled: Re: Can we replace adjuvant chemotherapy with surveillance for stage IA-C immature ovarian teratomas of any grade? An international multicenter analysis
We have read with interest the letter to you from Dr Lockley and colleagues [1] published in response to our manuscript entitled ‘Can we replace adjuvant chemotherapy with surveillance for stage IA-C immature ovarian teratomas of any grade? an international multicenter analysis’ that supports surveillance rather than adjuvant chemotherapy in stage I immature teratomas (ITs). This paper was based on the evaluation of the o utcomes of 108 patients with pure ITs, as a result of an international collaboration [2]. (Source: European Journal of Cancer)
Source: European Journal of Cancer - June 8, 2021 Category: Cancer & Oncology Authors: Alice Bergamini, Naveed Sarwar, Gabriella Ferrandina, Giovanna Scarfone, Dee Short, Xianne Aguiar, Cristina Camnasio, Baljeet Kaur, Philip M. Savage, Gennaro Cormio, Adrian Lim, Sandro Pignata, Giorgia Mangili, Michael J. Seckl Tags: Author ’s reply Source Type: research
Response to the Letter to the Editor by Lockley et al. commenting on ‘Can we replace adjuvant chemotherapy with surveillance for stage IA-C immature ovarian teratomas of any grade? an international multicenter analysis’
We have read with interest the letter to you from Dr Lockley and colleagues [1] published in response to our manuscript entitled ‘Can we replace adjuvant chemotherapy with surveillance for stage IA-C immature ovarian teratomas of any grade? an international multicenter analysis’ that supports surveillance rather than adjuvant chemotherapy in stage I immature teratomas (ITs). This paper was based on the evaluation of the o utcomes of 108 patients with pure ITs, as a result of an international collaboration [2]. (Source: European Journal of Cancer)
Source: European Journal of Cancer - June 8, 2021 Category: Cancer & Oncology Authors: Alice Bergamini, Naveed Sarwar, Gabriella Ferrandina, Giovanna Scarfone, Dee Short, Xianne Aguiar, Cristina Camnasio, Baljeet Kaur, Philip M. Savage, Gennaro Cormio, Adrian Lim, Sandro Pignata, Giorgia Mangili, Michael J. Seckl Tags: Author ’s reply Source Type: research
Anti-N-Methyl-D-Aspartate Receptor Encephalitis Associated with Ovarian Teratoma in South China-Clinical Features, Treatment, Immunopathology, and Surgical Outcomes of 21 Cases
CONCLUSION: The disease is of high prevalence in autumn and winter. The central hypoventilation symptom and mature ovarian teratomas were associated with surgical outcome. NMDAR-positive neural tissue is not the only etiological factor of encephalitis. We speculate that encephalitis development in some patients may result from NMDAR expression in sebaceous glands and squamous epithelial tissues.PMID:34093900 | PMC:PMC8163540 | DOI:10.1155/2021/9990382 (Source: Disease Markers)
Source: Disease Markers - June 7, 2021 Category: Laboratory Medicine Authors: Huiyun Jiang Huixia Ye Yifeng Wang Yunhui Li Ying Wang Xiaomao Li Source Type: research
Re: ‘Can we replace adjuvant chemotherapy with surveillance for stage IA-C immature ovarian teratomas of any grade? An international multicenter analysis’
The article by Bergamini et al. [1] adds to the growing body of evidence supporting surveillance, rather than adjuvant chemotherapy, in the postoperative management of ovarian immature teratomas (IT). Postop surveillance is established for paediatric IT [2–5] yet international guidelines continue to recommend adjuvant chem otherapy for nearly all adults [6,7]. The authors highlight studies suggesting that postoperative surveillance may also be safe for adult patients [8], particularly in stage I disease [9], but rightly point out that clinical evidence is extremely sparse. (Source: European Journal of Cancer)
Source: European Journal of Cancer - June 4, 2021 Category: Cancer & Oncology Authors: Michelle Lockley, Sara Stoneham, Jonathan Shamash, Farzana Pashankar, Lindsay Frazier Tags: Letter to the Editor Source Type: research
Extragonadal teratomas in women and adolescent girls: A systematic review
CONCLUSIONS: While rare, EGTs should be considered when evaluating pelviabdominal masses with imaging characteristics consistent with teratomas. Confirmation is usually intraoperative and a laparoscopic approach is reasonable if there is good surgeon comfort and the size is about 5 cm.PMID:34022590 | DOI:10.1016/j.ejogrb.2021.05.005 (Source: Reproductive Biology)
Source: Reproductive Biology - May 22, 2021 Category: Reproduction Medicine Authors: Abhiram Kanneganti Poornima Bhadiraju Pearl Shuang Ye Tong Source Type: research
