Significance of Estrogen/Progesterone Receptor Expression in Metaplastic Breast Carcinoma
CONCLUSION: MBC is a rare breast neoplasm. MBC was found to be triple negative in most cases, but a significant percentage were HR (ER/PR) positive. Moreover, we found an association between HR status and various clinicopathological features, indicating that HR status is a significant predictor of MBC prognosis.PMID:38601434 | PMC:PMC11006451 | DOI:10.1155/2024/2540356 (Source: Disease Markers)
Source: Disease Markers - April 11, 2024 Category: Laboratory Medicine Authors: Atif Ali Hashmi Bakhtawar Allauddin Mallick Khushbakht Rashid Umair Arshad Malik Shamail Zia Fazail Zia Muhammad Irfan Source Type: research

Determination of Tumor Marker Screening for Lung Cancer Using ROC Curves
CONCLUSION: The five tumor markers-CEA, CA125, CY211, NSE, GRP-show promising results in screening healthy individuals and patients with lung cancer. However, only CEA, NSE, and GRP effectively differentiate patients with benign lung lesions from those with lung cancer. A single tumor marker has limited utility in detecting and screening for lung cancer and should be combined with other tumor markers. CEA + CA125 emerges as a superior tumor marker for distinguishing healthy individuals from those with lung cancer, whereas the CEA + NSE combination is more effective in identifying tumor markers in patients with benign lung ...
Source: Disease Markers - March 29, 2024 Category: Laboratory Medicine Authors: Xiaofeng Dou Jiachen Lu Yingying Yu Yaohui Yi Ling Zhou Source Type: research

Plasma microRNA-320c as a Potential Biomarker for the Severity of Knee Osteoarthritis and Regulates cAMP Responsive Element Binding Protein 5 (CREB5) in Chondrocytes
CONCLUSION: Our results indicate that plasma miR-320c may serve as a potential novel predictor of the severity of knee OA and that miR-320c may play an important role in the pathogenesis of OA through inhibiting the cAMP pathway by targeting CREB5.PMID:38549717 | PMC:PMC10973101 | DOI:10.1155/2024/9936295 (Source: Disease Markers)
Source: Disease Markers - March 29, 2024 Category: Laboratory Medicine Authors: Rongwei Zhou Like Zhao Qian Wang Yongjing Cheng Miao Song Cibo Huang Source Type: research

Determination of Tumor Marker Screening for Lung Cancer Using ROC Curves
CONCLUSION: The five tumor markers-CEA, CA125, CY211, NSE, GRP-show promising results in screening healthy individuals and patients with lung cancer. However, only CEA, NSE, and GRP effectively differentiate patients with benign lung lesions from those with lung cancer. A single tumor marker has limited utility in detecting and screening for lung cancer and should be combined with other tumor markers. CEA + CA125 emerges as a superior tumor marker for distinguishing healthy individuals from those with lung cancer, whereas the CEA + NSE combination is more effective in identifying tumor markers in patients with benign lung ...
Source: Disease Markers - March 29, 2024 Category: Laboratory Medicine Authors: Xiaofeng Dou Jiachen Lu Yingying Yu Yaohui Yi Ling Zhou Source Type: research

Plasma microRNA-320c as a Potential Biomarker for the Severity of Knee Osteoarthritis and Regulates cAMP Responsive Element Binding Protein 5 (CREB5) in Chondrocytes
CONCLUSION: Our results indicate that plasma miR-320c may serve as a potential novel predictor of the severity of knee OA and that miR-320c may play an important role in the pathogenesis of OA through inhibiting the cAMP pathway by targeting CREB5.PMID:38549717 | PMC:PMC10973101 | DOI:10.1155/2024/9936295 (Source: Disease Markers)
Source: Disease Markers - March 29, 2024 Category: Laboratory Medicine Authors: Rongwei Zhou Like Zhao Qian Wang Yongjing Cheng Miao Song Cibo Huang Source Type: research

Determination of Tumor Marker Screening for Lung Cancer Using ROC Curves
CONCLUSION: The five tumor markers-CEA, CA125, CY211, NSE, GRP-show promising results in screening healthy individuals and patients with lung cancer. However, only CEA, NSE, and GRP effectively differentiate patients with benign lung lesions from those with lung cancer. A single tumor marker has limited utility in detecting and screening for lung cancer and should be combined with other tumor markers. CEA + CA125 emerges as a superior tumor marker for distinguishing healthy individuals from those with lung cancer, whereas the CEA + NSE combination is more effective in identifying tumor markers in patients with benign lung ...
Source: Disease Markers - March 29, 2024 Category: Laboratory Medicine Authors: Xiaofeng Dou Jiachen Lu Yingying Yu Yaohui Yi Ling Zhou Source Type: research

Plasma microRNA-320c as a Potential Biomarker for the Severity of Knee Osteoarthritis and Regulates cAMP Responsive Element Binding Protein 5 (CREB5) in Chondrocytes
CONCLUSION: Our results indicate that plasma miR-320c may serve as a potential novel predictor of the severity of knee OA and that miR-320c may play an important role in the pathogenesis of OA through inhibiting the cAMP pathway by targeting CREB5.PMID:38549717 | PMC:PMC10973101 | DOI:10.1155/2024/9936295 (Source: Disease Markers)
Source: Disease Markers - March 29, 2024 Category: Laboratory Medicine Authors: Rongwei Zhou Like Zhao Qian Wang Yongjing Cheng Miao Song Cibo Huang Source Type: research

Determination of Tumor Marker Screening for Lung Cancer Using ROC Curves
CONCLUSION: The five tumor markers-CEA, CA125, CY211, NSE, GRP-show promising results in screening healthy individuals and patients with lung cancer. However, only CEA, NSE, and GRP effectively differentiate patients with benign lung lesions from those with lung cancer. A single tumor marker has limited utility in detecting and screening for lung cancer and should be combined with other tumor markers. CEA + CA125 emerges as a superior tumor marker for distinguishing healthy individuals from those with lung cancer, whereas the CEA + NSE combination is more effective in identifying tumor markers in patients with benign lung ...
Source: Disease Markers - March 29, 2024 Category: Laboratory Medicine Authors: Xiaofeng Dou Jiachen Lu Yingying Yu Yaohui Yi Ling Zhou Source Type: research

Plasma microRNA-320c as a Potential Biomarker for the Severity of Knee Osteoarthritis and Regulates cAMP Responsive Element Binding Protein 5 (CREB5) in Chondrocytes
CONCLUSION: Our results indicate that plasma miR-320c may serve as a potential novel predictor of the severity of knee OA and that miR-320c may play an important role in the pathogenesis of OA through inhibiting the cAMP pathway by targeting CREB5.PMID:38549717 | PMC:PMC10973101 | DOI:10.1155/2024/9936295 (Source: Disease Markers)
Source: Disease Markers - March 29, 2024 Category: Laboratory Medicine Authors: Rongwei Zhou Like Zhao Qian Wang Yongjing Cheng Miao Song Cibo Huang Source Type: research

Determination of Tumor Marker Screening for Lung Cancer Using ROC Curves
CONCLUSION: The five tumor markers-CEA, CA125, CY211, NSE, GRP-show promising results in screening healthy individuals and patients with lung cancer. However, only CEA, NSE, and GRP effectively differentiate patients with benign lung lesions from those with lung cancer. A single tumor marker has limited utility in detecting and screening for lung cancer and should be combined with other tumor markers. CEA + CA125 emerges as a superior tumor marker for distinguishing healthy individuals from those with lung cancer, whereas the CEA + NSE combination is more effective in identifying tumor markers in patients with benign lung ...
Source: Disease Markers - March 29, 2024 Category: Laboratory Medicine Authors: Xiaofeng Dou Jiachen Lu Yingying Yu Yaohui Yi Ling Zhou Source Type: research

Plasma microRNA-320c as a Potential Biomarker for the Severity of Knee Osteoarthritis and Regulates cAMP Responsive Element Binding Protein 5 (CREB5) in Chondrocytes
CONCLUSION: Our results indicate that plasma miR-320c may serve as a potential novel predictor of the severity of knee OA and that miR-320c may play an important role in the pathogenesis of OA through inhibiting the cAMP pathway by targeting CREB5.PMID:38549717 | PMC:PMC10973101 | DOI:10.1155/2024/9936295 (Source: Disease Markers)
Source: Disease Markers - March 29, 2024 Category: Laboratory Medicine Authors: Rongwei Zhou Like Zhao Qian Wang Yongjing Cheng Miao Song Cibo Huang Source Type: research