Practices and Perceptions Among Surgical Oncologists in the Perioperative Care of Obese Cancer Patients
AbstractBackgroundObesity and cancer are two common diseases in the United States. Although there is an interaction of obesity and cancer, little is known about surgeon perceptions and practices in the care of obese cancer patients. We sought to characterize perceptions and practices of surgical oncologists regarding the perioperative care of obese patients being treated for cancer.MethodsA cross-sectional survey was designed, pilot tested, and utilized to assess perceptions and practices of surgeons treating cancer patients. Surgical oncologists were identified using a commercially available database, and Qualtrics® w...
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Resection of a Perirectal Leiomyosarcoma via a Posterior Transcoccygeal Approach
ConclusionThe Kraske approach allows for adequate resection, while avoiding the morbidity of the transabdominal approach, and allowing the patient to maintain a continent rectum. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Decreasing Use of Axillary Dissection in Node-Positive Breast Cancer Patients Treated with Neoadjuvant Chemotherapy
AbstractBackgroundNeoadjuvant chemotherapy (NAC) may downstage axillary disease in node-positive breast cancer. Several clinical trials have shown that sentinel lymph node (SLN) surgery after NAC is feasible for these patients. We sought to evaluate the use of SLN surgery and ALND in cN1 patients undergoing NAC.MethodsWe identified all patients with biopsy-proven cN1 breast cancer treated with NAC at our institution between January 2009 and December 2017. Approximated biologic subtype was determined by estrogen receptor (ER) and human epidermal growth factor receptor 2 (HER2) status. Cochran –Armitage trend and Chi s...
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

MelMART Trial: It ’s Now or Never
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Identification of microRNA Biomarkers of Response to Neoadjuvant Chemoradiotherapy in Esophageal Adenocarcinoma Using Next Generation Sequencing
ConclusionsmiRNA-ratio biomarkers identified using next generation sequencing can be used to predict disease free survival following neoadjuvant chemoradiotherapy and esophagectomy in patients with esophageal adenocarcinoma. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Risk Factors for Postoperative Chylothorax After Radical Subtotal Esophagectomy
ConclusionsThis study revealed that post-chemoradiotherapy and high intraoperative fluid balance are predictors of chylothorax after esophagectomy. The elucidation of clinicopathological factors that can predict the incidence of chylothorax will help to establish more effective perioperative management for esophageal cancer patients. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Tumor Size and Presence of Metastatic Disease at Diagnosis are Associated with Disease-Specific Survival in Parathyroid Carcinoma
The objectives of this study were to evaluate the trends in incidence and assess prognostic factors.MethodsA retrospective review of the SEER database between 1973 and 2014 was performed, identifying 520 patients with parathyroid carcinoma. Population-adjusted incidence rates were calculated in 4-year intervals. A Cochrane-Armitage test was performed to analyze changes in trend in incidence, tumor size, and extent of disease. Age, year of diagnosis, race, gender, extent of disease, surgical resection, treatment with radiation, tumor size, and lymph node status were assessed using Mantel-Cox log rank test. Multivariate anal...
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Intraoperative Nomograms, Based on One-Step Nucleic Acid Amplification, for Prediction of Non-sentinel Node Metastasis and Four or More Axillary Node Metastases in Breast Cancer Patients with Sentinel Node Metastasis
ConclusionsWe constructed intraoperative nomograms using OSNA for the prediction of NSLN metastasis and four or more ALN metastases. These nomograms are as accurate as the conventional postoperative nomograms and might be helpful for decision making regarding the indication for cALND or the choice of adjuvant chemotherapeutic regimens and radiation field. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Development of Patient-Derived Gastric Cancer Organoids from Endoscopic Biopsies and Surgical Tissues
ConclusionsOur study results demonstrate the feasibility of developing gastric cancer PDOs from EGD biopsies. These results also indicate that endoscopic-derived PDOs are accurate surrogates of the primary tumor and have the potential for drug sensitivity screening and personalized medicine applications. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Extracellular Vesicle RNA Sequencing Reveals Dramatic Transcriptomic Alterations Between Metastatic and Primary Osteosarcoma in a Liquid Biopsy Approach
ConclusionWe have demonstrated a liquid biopsy-based approach for tracking cancer transcriptomic alterations, which is a promising source of prognostic and therapeutic biomarkers for metastatic OS.Clinical Trial RegistrationNCT03108677. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Robotic Prophylactic Nipple-Sparing Mastectomy with Immediate Prosthetic Breast Reconstruction: A Prospective Study
ConclusionsPreliminary data attest to the feasibility, the reproducibility, and the safety of this approach. However, long-term data are needed to confirm the oncological safety and the esthetic stability of the result.Trial registration identifier NCT02673268. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Impact of a Surgical Sealing Patch on Lymphatic Drainage After Axillary Dissection for Breast Cancer: The SAKK 23/13 Multicenter Randomized Phase III Trial
ConclusionsTachoSil® reduced drainage after axillary dissection for breast cancer neither significantly nor relevantly. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

1 Versus 2-cm Excision Margins for pT2-pT4 Primary Cutaneous Melanoma (MelMarT): A Feasibility Study
We report the results of a pilot international study (MelMarT) comparing a 1 versus 2-cm surgical margin for patients with primary melan oma >  1 mm in BT.MethodsThis phase III, multicentre trial [NCT02385214] administered by the Australia& New Zealand Medical Trials Group (ANZMTG 03.12) randomised patients with a primary cutaneous melanoma  >  1 mm in BT to a 1 versus 2-cm wide excision margin to be performed with sentinel lymph node biopsy. Surgical closure technique was at the discretion of the treating surgeon. Patients’ QoL was measured (FACT-M questionnaire) at ba...
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Impact of Extent of Surgery on Tumor Recurrence and Survival for Papillary Thyroid Cancer Patients
ConclusionsWhile the quality of the data limit the strength of our conclusions, and while tumor characteristics, patient risk factors, and preferences should be considered, most data support that lobectomy and total thyroidectomy yield comparable oncologic outcomes for PTC measuring 1.0 –4.0 cm. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Cervical Esophageal Cancer Treatment Strategies: A Cohort Study Appraising the Debated Role of Surgery
ConclusionsDefinitive platinum-based CRT should be the treatment of choice for cervical esophageal cancer. Surgery has a role for patients with non-complete response as it adds significant survival benefit, with acceptable morbidity and mortality. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Long-Term Oncologic Outcomes Following Robotic Liver Resections for Primary Hepatobiliary Malignancies: A Multicenter Study
ConclusionsRLS can be performed for primary hepatobiliary malignancies with long-term oncologic outcomes comparable to published open and laparoscopic data. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Oncoplastic Surgery in Breast Cancer: Don ’t Forget the Boost!
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Screening Mammography: Getting to Version 2.0
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Editorial Comment to “Robotic-Assisted Surgery for Upper Tract Urothelial Carcinoma: A Comparative Survival Analysis”
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Joint Statement by the Surgery Journal Editors Group: Adopted by the Annals of Surgical Oncology
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 1, 2018 Category: Cancer & Oncology Source Type: research

Techniques for Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Surgical Management of Lobular Carcinoma In Situ: Analysis of the National Cancer Database
This study aimed to investigate national practice patterns and factors associated with unilateral mastectomy.MethodsThe study used the National Cancer Database to identify women with a diagnosis of LCIS from 2004 to 2013. Descriptive statistics were used to describe surgical treatment, and multinomial logistic regression was used to identify temporal, patient, and facility-level factors associated with receipt of uni- and bilateral mastectomy.ResultsThe study identified 30,105 women with LCIS. Of these woman, 5.4% received no surgery, 84.8% had surgical excision, 4% underwent unilateral mastectomy, and 5.1% underwent bilat...
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Evaluation of the Relationship Between Flap Tension and Tissue Perfusion in Implant-Based Breast Reconstruction Using Laser-Assisted Indocyanine Green Angiography
ConclusionsIt was objectively proven that tissue perfusion deteriorates as the tension applied on the flap increases. On the basis of this finding, we can control the amount of inflation volume of the expander or remove the skin in the pre-ischaemic condition to reduce complications of implant-based breast reconstruction. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Cost Effectiveness of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Management of Colorectal Peritoneal Carcinomatosis
ConclusionThe findings show that CRS and HIPEC results in prolonged survival for selected patients with colorectal peritoneal carcinomatosis and a lower cost per life year attained than for the traditionally used palliative chemotherapy. It should logically be the preferred treatment of choice for selected patients with colorectal peritoneal metastasis. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Management of Mucinous Appendiceal Tumors
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Metastatic Melanoma to the Colon, Rectum, and Anus: A 50-Year Experience
ConclusionOur study provides insights into melanoma metastatic to the colon, rectum, and anus, which had an incidence of 0.3%. There are potentially long intervals between diagnosis of primary melanoma and large bowel metastasis. The most common symptom was rectal bleeding, although some patients were asymptomatic. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Neoadjuvant Chemotherapy Use in Breast Cancer is Greatest in Excellent Responders: Triple-Negative and HER2+ Subtypes
AbstractBackgroundWhile breast cancer has historically been treated with surgery followed by adjuvant chemotherapy (AC) and radiation when indicated, neoadjuvant chemotherapy (NAC) use is thought to be increasing; however, the trends of its use in various biological subtypes have not been evaluated. We sought to evaluate the trend of NAC use over time by biological subtype.MethodsWe identified all patients with invasive breast cancer who underwent curative intent surgery and were treated with chemotherapy from 2010 to 2015 from the National Cancer Database. An unadjusted analysis of trends in proportions over time was perf...
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Inhibition Mechanism of Acellular Dermal Matrix on Capsule Formation in Expander –Implant Breast Reconstruction After Postmastectomy Radiotherapy
ConclusionsUse of ADM reduced myofibroblasts, vascularity, fibroblasts, and EndoMT in capsule tissues. Moreover, ADM use decreased macrophages, a key regulator of tissue fibrosis, as well asTGF-β1 andPDGF-B expression. We hope that these results provide basic concepts important for prevention of capsular contracture. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Long-Term Outcome After Surgery for a Localized Retroperitoneal Soft Tissue Sarcoma in Elderly Patients: Results from a Retrospective, Single-Center Study
ConclusionsCurative surgery is feasible in selected elderly patients but with higher mortality and morbidity rates than in younger patients. It enables a prolonged survival. Future studies should focus on selection process to minimize postoperative mortality and morbidity. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Walking the Fine Line of Axillary Management in Mastectomy Patients
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Strategic Delay: Histology- and Biology-Driven Decision-Making in Recurrent Retroperitoneal Sarcoma
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Multicenter Study of Presentation, Management, and Postoperative and Long-Term Outcomes of Septegenerians and Octogenerians Undergoing Gastrectomy for Gastric Cancer
ConclusionThe data suggest that patients 70 –79 years of age show a risk of postoperative death comparable with that of younger subjects. However, patients older than 80 years should be carefully selected for surgical treatment due to the increased risk of postoperative mortality. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Minimally Invasive Surgery for Retroperitoneal Sarcoma: Just Because We Can Does Not Mean We Should
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Compliance with an Enhanced Recovery After a Surgery Program for Patients Undergoing Gastrectomy for Gastric Carcinoma: A Phase 2 Study
This study investigated compliance with the main elements of ERAS for patients undergoing gastrectomy for gastric carcinoma.MethodsThis phase 2 study enrolled 168 patients undergoing elective gastrectomy for gastric carcinoma. An ERAS program consisting of 18 main elements was implemented, and compliance with each element was evaluated (ClinicalTrials.gov, NCT01653496).ResultsDistal gastrectomy was performed for 142 patients (84.5%) and total gastrectomy for 26 patients (10.1%). Laparoscopic surgery was performed for 141 patients (86%). The postoperative morbidity rate was 9.5%, and the mortality rate was 0%. The rates of ...
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Comparison of Outcome of Esophagectomy Versus Nonsurgical Treatment for Resectable Esophageal Cancer with Clinical Complete Response to Neoadjuvant Therapy
ConclusionsWith improved diagnostic accuracy, nonsurgical treatment can be an option for patients estimated as cCR after treatment administered in a neoadjuvant setting. However, surgical resection is considered more appropriate because of residual tumor in some patients with cCR and because of superior DSS and RFS following esophagectomy compared with nonsurgical treatment. Future studies must focus on ameliorating late postoperative complications, such as respiratory failure and aspiration pneumonia. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Crystal Ball or Magic8 Ball? Reply Hazy, Try Again
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Heterogeneity in Outcomes of Pathologic T1-2N1 Breast Cancer After Mastectomy: Looking Beyond Locoregional Failure Rates
ConclusionsPatients with pT1-2pN1 represent a heterogeneous group with a wide range of LRF/DM rates. In particular, patients with pT1 tumors and 1  + LN, and patients with micrometastases, had low event rates. These groups would derive small absolute reductions in LRF and DM with addition of PMRT, underscoring the importance of patient selection for PMRT in pT1-2pN1 breast cancer. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Routine Axillary Ultrasound for Patients with T1 –T2 Breast Cancer Does Not Increase the Rate of Axillary Lymph Node Dissection Based on Predictive Modeling
DiscussionUse of AUS may help to tailor patient care without leading to overutilization of ALND, as long as neoadjuvant chemotherapy is administered when appropriate. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

RNA-Seq of Circulating Tumor Cells in Stage II –III Breast Cancer
ConclusionIt is feasible to use RNA-seq of CTCs in non-metastatic patients to discover novel tumor biology characteristics. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - July 2, 2018 Category: Cancer & Oncology Source Type: research

Postoperative Adjuvant Trans-Arterial Chemoembolization for Patients with Hepatocellular Carcinoma and Portal Vein Tumor Thrombus
ConclusionsIn patients with HCC and PVTT, PA-TACE was associated with a lower risk of death, particularly, among those with PVTT involving right/left or main portal vein, after excluding patients who were unsuitable for this procedure at 1  month after surgery. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - May 30, 2018 Category: Cancer & Oncology Source Type: research

Treatment of Isolated Peritoneal Recurrences in Patients with Colorectal Peritoneal Metastases Previously Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
This study aimed to evaluate the management of isolated peritoneal recurrence after primary CRS-HIPEC.MethodsIn two tertiary referral centers, all patients who underwent CRS-HIPEC for colorectal PC between 2004 and 2015 and who developed isolated peritoneal recurrences were retrospectively evaluated. Location, treatment of peritoneal recurrences, and curative or palliative treatment intent were reported, and univariable and multivariable Cox regression analysis and survival analyses were performed.ResultsOf 414 patients treated with CRS-HIPEC for colorectal PC, 106 patients (26%) developed isolated peritoneal recurrence. F...
Source: Annals of Surgical Oncology - May 30, 2018 Category: Cancer & Oncology Source Type: research

Rates of TP53 Mutation are Significantly Elevated in African American Patients with Gastric Cancer
ConclusionsSignificantly higher rates of TP53 mutations were identified among the African American patients with gastric adenocarcinoma. This is the first study to evaluate tumor genomic differences in a diverse population of patients with gastric adenocarcinoma. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - May 30, 2018 Category: Cancer & Oncology Source Type: research

Predictors of Residual Disease After Breast Conservation Surgery
AbstractIntroductionBreast-conserving therapy is the standard of care for early-stage breast cancer. In the era of multimodality therapy, the debate on the value of revision surgery for compromised margins continues, and high re-excision rates persist despite updated guidelines. Our study sought to identify the local re-excision rate for compromised margins after lumpectomy, and identify predictors of residual disease at re-excision.MethodsThis population-based retrospective cohort study included women with breast cancer who underwent a lumpectomy between 2009 and 2012 in Manitoba, with close ( ≤ 2 mm) or posi...
Source: Annals of Surgical Oncology - May 30, 2018 Category: Cancer & Oncology Source Type: research

Salvage Abdominoperineal Resection for Squamous Cell Anal Cancer: A 30-Year Single-Institution Experience
ABSTRACTBackgroundFailure of chemoradiotherapy (CRT) for anal squamous cell carcinoma (SCC) results in persistent or recurrent anal SCC. Treatment with salvage abdominoperineal resection (APR) can potentially achieve cure. The aims of this study are to analyze oncological and surgical outcomes of our 30-year experience with salvage APR for anal SCC after failed CRT and identify prognostic factors for overall survival (OS).MethodsAll consecutive patients who underwent salvage APR between 1990 and 2016 for histologically confirmed persistent or recurrent anal SCC after failed CRT were retrospectively analyzed.ResultsForty-se...
Source: Annals of Surgical Oncology - May 30, 2018 Category: Cancer & Oncology Source Type: research

Will Palliative Care Ever Be Cool?
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - May 30, 2018 Category: Cancer & Oncology Source Type: research

Adjuvant Therapy in the Treatment of Melanoma
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - May 30, 2018 Category: Cancer & Oncology Source Type: research

Is the 8th Edition of the AJCC TNM Staging System Sufficiently Reasonable for All Patients with Noncardia Gastric Cancer? A 12,549-Patient International Database Study
ConclusionsThe 8th edition of the AJCC TNM classification shows better prognostic ability than the 7th edition in noncardia GC patients with  >  15 eLNs, but no improvement was found in patients with ≤ 15 eLNs; therefore, a novel prognostic model is proposed. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - May 30, 2018 Category: Cancer & Oncology Source Type: research

Stage- and Histologic Subtype-Dependent Frequency of Lymph Node Metastases in Patients with Epithelial Ovarian Cancer Undergoing Systematic Pelvic and Paraaortic Lymphadenectomy
ConclusionsThe risk of LN metastases in patients with EOC is dependent on stage and histological subtype. Patients with incidental finding of early mucinous or low-grade endometrioid EOC are at very low risk of retroperitoneal lymph node metastases. Reoperation for lymph node staging only should be discussed individually with caution. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - May 30, 2018 Category: Cancer & Oncology Source Type: research

FOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel for Neoadjuvant Treatment of Resectable and Borderline Resectable Pancreatic Head Adenocarcinoma
This study aimed to compare neoadjuvant FOLFIRINOX and G-nP in the treatment of resectable (R) and borderline resectable (BR) head PDA.MethodsA single-institution retrospective review of R and BR patients undergoing pancreaticoduodenectomy after NAT with FOLFIRINOX or G-nP was performed. Comparative analysis was performed using inverse-probability-weighted (IPW) estimators. The end points of the study were overall survival (OS) and an 80% reduction in CA19-9 with NAT.ResultsIn this study, 193 patients were analyzed, with 73 patients receiving FOLFIRINOX and 120 patients receiving G-nP. The median OS was 38.7  months f...
Source: Annals of Surgical Oncology - May 30, 2018 Category: Cancer & Oncology Source Type: research

Efficacy of Endoscopic Ultrasonography for Determining Clinical T Category for Esophageal Squamous Cell Carcinoma: Data From 1434 Surgical Cases
AbstractBackgroundThe efficacy of endoscopic ultrasonography (EUS) for determining T category is variable for esophageal squamous cell carcinoma (ESCC). We aimed to assess the efficacy of EUS in accurately identifying T category for ESCC based on the 8th AJCCCancer Staging Manual.MethodsA retrospective analysis was conducted using a prospectively collected ESCC database from January 2003 to December 2015, in which all patients underwent EUS examination followed by esophagectomy. The efficacy of EUS was evaluated by sensitivity, specificity, and accuracy compared with pathological T category as gold standard. Overall surviv...
Source: Annals of Surgical Oncology - May 30, 2018 Category: Cancer & Oncology Source Type: research