Neuroectodermal Rosettes in Immature Teratomas Are Not the Counterpart of Embryonal Tumours With Multilayered Rosettes
CONCLUSION: Genetic changes associated with IMT differ from those in ETMR, but LIN28A protein immunohistochemical expression, which is specific for ETMR, can be a biomarker for the immature neuroepithelial component in IMT.PMID:36039462 | DOI:10.21873/anticanres.15934 (Source: Cell Research)
Source: Cell Research - August 30, 2022 Category: Cytology Authors: Naomi Magarifuchi Yuichi Yamada Yoshihiro Oishi Kiyoko Kato Kenichi Taguchi Yoshinao Oda Source Type: research
Ovarian teratoid carcinosarcoma with a PIK3CA mutation: a case report and review of the literature
AbstractOvarian teratoid carcinosarcoma involves an epithelial tumor of the M üllerian duct and an immature neuroepithelium, which is a characteristic of immature teratomas. Here, we describe the case of a 60-year-old woman who underwent surgery for a stage IC3 ovarian malignancy. The tumor showed a variety of histological features, including clear cell carcinoma, immature t eratoma, and rhabdomyosarcoma, and a PIK3CA mutation was detected at the same locus in each. Two months after surgery and before the start of chemotherapy, multiple bone and liver metastases were found. Four courses of combination therapy with vincris...
Source: International Cancer Conference Journal - August 8, 2022 Category: Cancer & Oncology Source Type: research
Immature ovarian teratoma in childhood: Case report of successful management of a monster mass in a preschool girl
CONCLUSION: In spite of immature ovarian teratomas having aggressive behaviour and lethal outcome, a high degree of suspicion and timely management can translate into a very good eventual prognosis.PMID:35846860 | PMC:PMC9283807 | DOI:10.1016/j.amsu.2022.104147 (Source: Annals of Medicine)
Source: Annals of Medicine - July 18, 2022 Category: Internal Medicine Authors: Pradeep Kajal Namita Bhutani Kirti Saini Preeti Kadian Source Type: research
Unusual Variants of Teratoma Involving the Gynecologic Tract
We report herein 2 rare forms of gynecologic teratomas: 1 case of immature teratoma of the uterus and 1 case of a benign follicular hamartoma arising in association with mature cystic teratoma of the ovary. (Source: International Journal of Gynecological Pathology)
Source: International Journal of Gynecological Pathology - June 29, 2022 Category: Pathology Tags: Pathology of the Upper Tract: Original Articles Source Type: research
Growing Teratoma Syndrome in the Setting of Sarcoidosis: A Case Report and Literature Review
We report a case of a 38 year old with mixed mature and immature teratomas who developed new peritoneal masses after adjuvant chemotherapy despite a normalization of tumor markers. In addition to low FDG uptake observed in these peritoneal masses, a PET scan showed hypermetabolic lymphadenopathy and pulmonary and spleen lesions suggesting widespread metastases. Subsequent surgical resection confirmed a mixed pathology with GTS and sarcoidosis. We reviewed the current literature evidence of GTS and sarcoidosis as a benign cause of lymphadenopathy in cancer patients. We emphasize the importance of a tissue diagnosis before i...
Source: Current Oncology - June 23, 2022 Category: Cancer & Oncology Authors: Adel Shahnam Robyn Sayer Unine Herbst Raghwa Sharma Won-Hee Yoon Tim Dinihan Bo Gao Source Type: research
Growing Teratoma Syndrome in the Setting of Sarcoidosis: A Case Report and Literature Review
We report a case of a 38 year old with mixed mature and immature teratomas who developed new peritoneal masses after adjuvant chemotherapy despite a normalization of tumor markers. In addition to low FDG uptake observed in these peritoneal masses, a PET scan showed hypermetabolic lymphadenopathy and pulmonary and spleen lesions suggesting widespread metastases. Subsequent surgical resection confirmed a mixed pathology with GTS and sarcoidosis. We reviewed the current literature evidence of GTS and sarcoidosis as a benign cause of lymphadenopathy in cancer patients. We emphasize the importance of a tissue diagnosis before i...
Source: Current Oncology - June 23, 2022 Category: Cancer & Oncology Authors: Adel Shahnam Robyn Sayer Unine Herbst Raghwa Sharma Won-Hee Yoon Tim Dinihan Bo Gao Source Type: research
