Growing Teratoma Syndrome in the Setting of Sarcoidosis: A Case Report and Literature Review

We report a case of a 38 year old with mixed mature and immature teratomas who developed new peritoneal masses after adjuvant chemotherapy despite a normalization of tumor markers. In addition to low FDG uptake observed in these peritoneal masses, a PET scan showed hypermetabolic lymphadenopathy and pulmonary and spleen lesions suggesting widespread metastases. Subsequent surgical resection confirmed a mixed pathology with GTS and sarcoidosis. We reviewed the current literature evidence of GTS and sarcoidosis as a benign cause of lymphadenopathy in cancer patients. We emphasize the importance of a tissue diagnosis before instituting therapy for presumed cancer recurrence to avoid potentially fatal diagnostic traps and management errors. A multiple disciplinary team approach is imperative in managing patients with suspected recurrent immature teratomas.PMID:35735440 | DOI:10.3390/curroncol29060331

Source: Current Oncology - June 23, 2022 Category: Cancer & Oncology Authors: Adel Shahnam Robyn Sayer Unine Herbst Raghwa Sharma Won-Hee Yoon Tim Dinihan Bo Gao Source Type: research